TYR / All / All

Total number of chains: 3054
Active chains: 408
Total number of genes: 91
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 932 30.5% AF-Q6ZMQ8-K1A
DFGin BLBplus 516 16.9% 6DI1A
DFGin ABAminus 357 11.7% 8BXHA
DFGout BBAminus 317 10.4% 5HG8A
DFGin None 309 10.1% 8BA3A
DFGin BLAplus 234 7.7% 8KH8A
DFGout None 129 4.2% 3G0EA
DFGin BLBtrans 101 3.3% 6V66A
DFGin BLBminus 59 1.9% 5NKGA
DFGinter None 52 1.7% 1P4OA
None None 32 1.0% 8VB5A
DFGinter BABtrans 16 0.5% 7YC9A
All chains
No PyMOL session because the query has >1000 chains
Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_label DFG-Asp_rotamer_label ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR AATK LMTK1_HUMAN AF-Q6ZMQ8-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 117 - 405 0 None None Serine/threonine-protein kinase LMTK1
TYR AATK LMTK1_HUMAN AF-Q6ZMQ8-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 117 - 405 0 None None Serine/threonine-protein kinase LMTK1
TYR ABL1 ABL1_HUMAN 2G2IA 3.12 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa ADP ATPlike 229 - 502 0 None H396P Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2G2IB 3.12 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa ADP ATPlike 232 - 500 0 None H396P Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2HZ4A 2.8 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-in TYR APEdihe_iiiai APEdist_aaaa 4ST Allosteric 234 - 500 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2HZ4C 2.8 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 4ST Allosteric 234 - 500 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 7N9GB 2.2 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa STI, 1N1 Allosteric, Type1 233 - 498 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN AF-P00519-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 234 - 503 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN AF-P00519-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 234 - 503 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 6XR6A 999.0 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 229 - 515 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 4TWPA 2.4 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa AXI Type1 233 - 503 0 None T315I Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 4TWPB 2.4 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa AXI Type1 233 - 503 0 None T315I Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2V7AA 2.5 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 627 Type1 233 - 503 0 PTR393 T315I Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2V7AB 2.5 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 627 Type1 234 - 503 0 PTR393 T315I Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2HZ4B 2.8 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 4ST Type1 233 - 498 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2GQGA 2.4 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 1N1 Type1 229 - 500 0 PTR393 None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2F4JA 1.91 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa VX6 Type1 227 - 513 0 None H396P Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2GQGB 2.4 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 1N1 Type1.5_Back 229 - 499 0 PTR393 None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 8SSNB 2.86 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nnnai APEdist_aaaa AY7, SKI Allosteric, Type1 64 - 506 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 8SSNA 2.86 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nnnai APEdist_aaaa AY7, SKI Allosteric, Type1.5_Back 64 - 507 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2G1TA 1.8 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 232 - 502 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2G1TB 1.8 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 230 - 502 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2G1TC 1.8 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 232 - 507 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2G1TD 1.8 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 229 - 502 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 7W7XA 2.0 Inactive DFGinter‑BABtrans DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa 8DW Type1 232 - 500 0 PTR393 None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 7W7XB 2.0 Inactive DFGinter‑BABtrans DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa 8DW Type1 232 - 500 0 PTR393 None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 4XEYB 2.891 Inactive DFGinter‑BABtrans DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa 1N1 Type1 122 - 504 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 7N9GA 2.2 Inactive DFGinter‑None DFGAsp-rot-out in-out out-none TYR APEdihe_nniai APEdist_aaaa STI, 1N1 Allosteric, Type1 233 - 498 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 7N9GC 2.2 Inactive DFGinter‑None DFGAsp-rot-out in-none out-none TYR APEdihe_nniai APEdist_aaaa STI, 1N1 Allosteric, Type1 234 - 499 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2G2FA 2.7 Inactive DFGinter‑None DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 232 - 506 0 None H396P Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 6BL8A 2.5 Inactive DFGinter‑None DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa PVB Type1 233 - 502 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 6BL8B 2.5 Inactive DFGinter‑None DFGAsp-rot-out in-none out-in TYR APEdihe_iiiai APEdist_aaaa PVB Type1 233 - 504 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 8I7SA 1.946 Inactive DFGinter‑None DFGAsp-rot-out in-in out-in TYR APEdihe_iiiai APEdist_aaaa 6CI Type1 232 - 500 0 PTR393 None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 8I7SB 1.946 Inactive DFGinter‑None DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa 6CI Type1 232 - 500 0 PTR393 None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 8I7ZB 2.255 Inactive DFGinter‑None DFGAsp-rot-out in-in out-in TYR APEdihe_iiiai APEdist_aaaa 6CI Type1 232 - 500 0 PTR393 None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 7W7YA 2.2 Inactive DFGinter‑None DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa 8IW Type1 232 - 500 0 PTR393 None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 7W7YB 2.2 Inactive DFGinter‑None DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa 8IW Type1 232 - 500 0 PTR393 None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 8H7FA 2.45 Inactive DFGinter‑None DFGAsp-rot-out in-none out-in TYR APEdihe_iiiai APEdist_aaaa QEW Type1 232 - 500 0 PTR393 None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 8H7FB 2.45 Inactive DFGinter‑None DFGAsp-rot-out in-none out-in TYR APEdihe_iiiai APEdist_aaaa QEW Type1 233 - 500 0 PTR393 None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 8H7HA 2.278 Inactive DFGinter‑None DFGAsp-rot-out in-none out-in TYR APEdihe_iiiai APEdist_aaaa QH9 Type1 232 - 500 0 PTR393 None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 8H7HB 2.278 Inactive DFGinter‑None DFGAsp-rot-out in-none out-in TYR APEdihe_iiiai APEdist_aaaa QH9 Type1 232 - 500 0 PTR393 None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 4ZOGA 2.3 Inactive DFGinter‑None DFGAsp-rot-out out-out out-in TYR APEdihe_iiiai APEdist_aaaa VX6 Type1 233 - 501 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 7CC2A 2.723 Inactive DFGinter‑None DFGAsp-rot-out out-out out-in TYR APEdihe_iiiai APEdist_aaaa FVC Type1 233 - 501 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 7CC2B 2.723 Inactive DFGinter‑None DFGAsp-rot-out in-none out-in TYR APEdihe_iiiai APEdist_aaaa FVC Type1 232 - 501 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 7DT2A 2.3 Inactive DFGinter‑None DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa HJ9 Type1 233 - 500 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 7DT2B 2.3 Inactive DFGinter‑None DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa HJ9 Type1 233 - 500 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2G2HA 2.0 Inactive DFGinter‑None DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa P16 Type1 233 - 504 0 None H396P Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 4XEYA 2.891 Inactive DFGinter‑None DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa 1N1 Type1 231 - 503 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 8I7ZA 2.255 Inactive DFGinter‑None DFGAsp-rot-out in-none out-in TYR APEdihe_iiiai APEdist_aaaa 6CI, BAL Type1, Type1 232 - 499 0 PTR393 None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 4YC8A 2.9 Inactive DFGinter‑None DFGAsp-rot-out out-none out-in TYR APEdihe_iiiai APEdist_aaaa 4B7 Type1.5_Front 233 - 501 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 4YC8B 2.9 Inactive DFGinter‑None DFGAsp-rot-out out-none out-in TYR APEdihe_iiiai APEdist_aaaa 4B7 Type1.5_Front 233 - 502 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 9KS5A 2.2 Inactive DFGinter‑None DFGAsp-rot-out in-na out-in TYR APEdihe_iiiai APEdist_aaaa A1EG1 Type1.5_Front 233 - 500 0 PTR393 None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 9KS5B 2.2 Inactive DFGinter‑None DFGAsp-rot-out in-na out-in TYR APEdihe_iiiai APEdist_aaaa A1EG1 Type1.5_Front 233 - 500 0 PTR393 None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 6XRGA 999.0 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-out TYR APEdihe_oiiai APEdist_aaaa No_ligand No_ligand 229 - 515 0 None G250E,M290L,T389Y Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 3QRJA 1.82 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 919 Type2 234 - 496 0 None T315I Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 3QRJB 1.82 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 919 Type2 233 - 497 0 None T315I Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2HZ0A 2.1 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa GIN Type2 233 - 497 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2HZ0B 2.1 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa GIN Type2 228 - 497 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2HYYA 2.4 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa STI Type2 235 - 498 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2HYYB 2.4 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa STI Type2 233 - 498 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2HYYC 2.4 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa STI Type2 233 - 498 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2HYYD 2.4 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa STI Type2 233 - 498 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 3CS9A 2.21 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa NIL Type2 233 - 500 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 3CS9B 2.21 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa NIL Type2 233 - 500 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 3CS9C 2.21 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa NIL Type2 232 - 497 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 3CS9D 2.21 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa NIL Type2 233 - 500 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 3QRIA 2.1 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 919 Type2 229 - 498 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 3QRIB 2.1 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 919 Type2 232 - 498 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2HIWA 2.2 Inactive DFGout‑BBAminus DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa 7MP Type2 230 - 499 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2HIWB 2.2 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 7MP Type2 230 - 499 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2E2BA 2.2 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 406 Type2 229 - 502 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2E2BB 2.2 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-in TYR APEdihe_iiiai APEdist_aaaa 406 Type2 229 - 497 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 5HU9A 1.529 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-out TYR APEdihe_oiiai APEdist_aaaa 66K, 66K Type2, Allosteric 229 - 499 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 3PYYA 1.85 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa STI, 3YY Type2, Allosteric 232 - 500 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 3PYYB 1.85 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-in TYR APEdihe_iiiai APEdist_aaaa STI, 3YY Type2, Allosteric 233 - 510 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 6NPEA 2.15 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa STI, KWD Type2, Allosteric 232 - 500 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 6NPEB 2.15 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa STI, KWD Type2, Allosteric 233 - 511 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 6NPUA 2.33 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa STI, KWV Type2, Allosteric 232 - 500 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 6NPUB 2.33 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-in TYR APEdihe_iiiai APEdist_aaaa STI, KWV Type2, Allosteric 233 - 510 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 6NPVA 1.86 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa STI, KWP Type2, Allosteric 232 - 500 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 6NPVB 1.86 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-in TYR APEdihe_iiiai APEdist_aaaa STI, KWP Type2, Allosteric 233 - 510 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 3QRKA 2.3 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 9DP Type3 229 - 496 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2G2FB 2.7 Inactive DFGout‑None DFGAsp-rot-out in-in out-in TYR APEdihe_iiiai APEdist_aaaa AGS ATPlike 234 - 502 0 None H396P Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 6XR7A 999.0 Inactive DFGout‑None DFGAsp-rot-out in-in out-out TYR APEdihe_ooiai APEdist_aaaa No_ligand No_ligand 229 - 515 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 8I7TB 2.8 Inactive DFGout‑None DFGAsp-rot-out in-in out-in TYR APEdihe_iiiai APEdist_aaaa 6I5 Type1 232 - 500 0 PTR393 None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2HZIA 1.7 Inactive DFGout‑None DFGAsp-rot-out in-in out-in TYR APEdihe_iiiai APEdist_aaaa JIN Type1 233 - 500 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 4ZOGB 2.3 Inactive DFGout‑None DFGAsp-rot-out in-in out-in TYR APEdihe_iiiai APEdist_aaaa VX6 Type1 234 - 503 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 4WA9B 2.2 Inactive DFGout‑None DFGAsp-rot-out in-in out-in TYR APEdihe_iiiai APEdist_aaaa AXI Type1 246 - 508 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 3UE4A 2.424 Inactive DFGout‑None DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa DB8 Type1 233 - 502 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 3UE4B 2.424 Inactive DFGout‑None DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa DB8 Type1 233 - 502 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 8I7TA 2.8 Inactive DFGout‑None DFGAsp-rot-out in-in out-in TYR APEdihe_iiiai APEdist_aaaa 6I5 Type1.5_Back 232 - 500 0 PTR393 None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2HZIB 1.7 Inactive DFGout‑None DFGAsp-rot-out in-in out-in TYR APEdihe_iiiai APEdist_aaaa JIN Type1.5_Back 233 - 500 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2G2HB 2.0 Inactive DFGout‑None DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa P16 Type1.5_Back 233 - 504 0 None H396P Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2FO0A 2.27 Inactive DFGout‑None DFGAsp-rot-out in-in out-in TYR APEdihe_iiiai APEdist_aaaa P16 Type1.5_Back 46 - 511 0 SEP50 D363N Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 1OPLA 3.42 Inactive DFGout‑None DFGAsp-rot-out in-in out-in TYR APEdihe_iiiai APEdist_aaaa P16 Type1.5_Back 62 - 512 0 None K12R,D363N Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 1OPLB 3.42 Inactive DFGout‑None DFGAsp-rot-out in-in out-in TYR APEdihe_iiiai APEdist_aaaa P16 Type1.5_Back 121 - 499 0 None K12R,D363N Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 5MO4A 2.17 Inactive DFGout‑None DFGAsp-rot-in in-in none-out TYR APEdihe_nnoai APEdist_aaaa NIL, AY7 Type2, Allosteric 64 - 512 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 4WA9A 2.2 Inactive None‑None DFGAsp-rot-out none-none out-in TYR APEdihe_iiiai APEdist_aaaa AXI Type1 246 - 504 0 None None Tyrosine-protein kinase ABL1
TYR ABL2 ABL2_HUMAN AF-P42684-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 280 - 549 0 None None Tyrosine-protein kinase ABL2
TYR ABL2 ABL2_HUMAN AF-P42684-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 280 - 549 0 None None Tyrosine-protein kinase ABL2
TYR ABL2 ABL2_HUMAN 2XYNA 2.81 Inactive DFGin‑BLAminus DFGAsp-rot-out in-none in-in TYR APEdihe_iiiai APEdist_aaaa VX6 Type1 280 - 545 0 None None Tyrosine-protein kinase ABL2
TYR ABL2 ABL2_HUMAN 2XYNB 2.81 Inactive DFGin‑BLAminus DFGAsp-rot-out in-none in-in TYR APEdihe_iiiai APEdist_aaaa VX6, VX6, VX6 Type1, Allosteric, Allosteric 280 - 545 0 None None Tyrosine-protein kinase ABL2
TYR ABL2 ABL2_HUMAN 2XYNC 2.81 Inactive DFGin‑BLAminus DFGAsp-rot-out in-none in-in TYR APEdihe_iiiai APEdist_aaaa VX6, VX6, VX6 Type1, Allosteric, Allosteric 281 - 544 0 None None Tyrosine-protein kinase ABL2
TYR ABL2 ABL2_HUMAN 3HMIA 1.65 Inactive DFGinter‑None DFGAsp-rot-out in-in out-in TYR APEdihe_iiiai APEdist_aaaa DKI Type1 279 - 546 0 None None Tyrosine-protein kinase ABL2
TYR ABL2 ABL2_HUMAN 3GVUA 2.05 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-none TYR APEdihe_niiai APEdist_aaaa STI, STI Type2, Allosteric 279 - 546 0 None None Tyrosine-protein kinase ABL2
TYR ALK ALK_HUMAN 3LCTA 2.1 Inactive DFGin‑ABAminus DFGAsp-rot-in in-none out-out TYR APEdihe_oiiai APEdist_aaaa ADP ATPlike 1093 - 1400 0 None S1281G ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4TT7A 2.1 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in out-out TYR APEdihe_oiiai APEdist_aaaa COM, COM Allosteric, Allosteric 1095 - 1400 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 7JY4A 2.42 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out out-out TYR APEdihe_oiiai APEdist_aaaa W47, W47 Allosteric, Type1 1096 - 1399 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 2YHVA 1.9 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out out-out TYR APEdihe_oiiai APEdist_aaaa No_ligand No_ligand 1093 - 1401 0 None L1196M ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4ANLA 1.7 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out out-out TYR APEdihe_oiiai APEdist_aaaa No_ligand No_ligand 1094 - 1402 0 None G1269A ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4FNWA 1.75 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in out-out TYR APEdihe_oiiai APEdist_aaaa No_ligand No_ligand 1084 - 1405 0 None C1097S,F1174L ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4FNXA 1.7 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in out-out TYR APEdihe_oiiai APEdist_aaaa No_ligand No_ligand 1093 - 1404 0 None C1097S,R1275Q ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 6CDTA 1.8 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out out-out TYR APEdihe_oiiai APEdist_aaaa No_ligand No_ligand 1093 - 1400 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 2YJSA 1.9 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out out-out TYR APEdihe_oiiai APEdist_aaaa No_ligand No_ligand 1094 - 1402 0 None C1156Y ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 3L9PA 1.8 Inactive DFGin‑ABAminus DFGAsp-rot-in in-none out-out TYR APEdihe_oiiai APEdist_aaaa No_ligand No_ligand 1093 - 1400 0 None S1281G ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4ANSA 1.85 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out out-out TYR APEdihe_oiiai APEdist_aaaa VGH Type1 1093 - 1402 0 None L1196M,G1269A ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 2YFXA 1.7 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out out-out TYR APEdihe_oiiai APEdist_aaaa VGH Type1 1093 - 1401 0 None L1196M ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4CLJA 1.66 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in out-out TYR APEdihe_oiiai APEdist_aaaa 5P8 Type1 1094 - 1402 0 None L1196M ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4CD0A 2.23 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in out-out TYR APEdihe_oiiai APEdist_aaaa AWJ Type1 1094 - 1402 0 None L1196M ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4ANQA 1.76 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out out-out TYR APEdihe_oiiai APEdist_aaaa VGH Type1 1093 - 1402 0 None G1269A ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 5AA9A 1.93 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out out-out TYR APEdihe_oiiai APEdist_aaaa 5P8 Type1 1093 - 1402 0 None L1198F ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 5AAAA 1.73 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out out-out TYR APEdihe_oiiai APEdist_aaaa VGH Type1 1093 - 1401 0 None L1198F ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 5AA8A 1.86 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out out-out TYR APEdihe_oiiai APEdist_aaaa 5P8 Type1 1093 - 1402 0 None C1156Y,L1198F ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 5AABA 2.2 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out out-out TYR APEdihe_oiiai APEdist_aaaa VGH Type1 1093 - 1402 0 None C1156Y,L1198F ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 6MX8A 1.96 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in none-out TYR APEdihe_oiiai APEdist_aaaa 6GY Type1 1094 - 1400 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 2XB7A 2.5 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in none-out TYR APEdihe_oiiai APEdist_aaaa GUI Type1 1095 - 1401 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 2XBAA 1.95 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in out-out TYR APEdihe_oiiai APEdist_aaaa 571 Type1 1095 - 1402 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 5FTOA 2.22 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in out-out TYR APEdihe_oiiai APEdist_aaaa YMX Type1 1094 - 1401 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 5FTQA 1.7 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in out-out TYR APEdihe_oiiai APEdist_aaaa U4W Type1 1094 - 1401 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 8ARJA 1.645 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in out-out TYR APEdihe_oiiai APEdist_aaaa NRR Type1 1103 - 1399 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 6E0RA 2.303 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out out-none TYR APEdihe_niiai APEdist_aaaa HKJ Type1 1099 - 1399 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 6EBWA 2.455 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out out-none TYR APEdihe_nniai APEdist_aaaa J3Y Type1 1096 - 1399 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 7JYRA 2.32 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out out-out TYR APEdihe_oiiai APEdist_aaaa VTA Type1 1095 - 1399 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 7JYSA 2.22 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in out-out TYR APEdihe_oiiai APEdist_aaaa VTD Type1 1095 - 1399 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 7JYTA 2.0 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out out-out TYR APEdihe_oiiai APEdist_aaaa VRM Type1 1095 - 1399 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 2XP2A 1.9 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out out-none TYR APEdihe_niiai APEdist_aaaa VGH Type1 1093 - 1401 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4CCBA 2.03 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in out-none TYR APEdihe_niiai APEdist_aaaa OFG Type1 1093 - 1401 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4CCUA 2.0 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out out-out TYR APEdihe_oiiai APEdist_aaaa AWF Type1 1093 - 1402 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4CLIA 2.05 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out out-out TYR APEdihe_oiiai APEdist_aaaa 5P8 Type1 1093 - 1401 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4CMOA 2.05 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out out-out TYR APEdihe_oiiai APEdist_aaaa YPW Type1 1093 - 1402 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4CMTA 1.73 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in out-none TYR APEdihe_niiai APEdist_aaaa GWH Type1 1093 - 1401 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4CMUA 1.8 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out out-out TYR APEdihe_oiiai APEdist_aaaa IV7 Type1 1093 - 1401 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4CNHA 1.9 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out out-none TYR APEdihe_niiai APEdist_aaaa 3U9 Type1 1094 - 1402 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4CTBA 1.79 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in out-out TYR APEdihe_oiiai APEdist_aaaa KVC Type1 1093 - 1402 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4CTCA 2.03 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out out-out TYR APEdihe_oiiai APEdist_aaaa J99 Type1 1094 - 1402 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 5KZ0A 2.3 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out out-out TYR APEdihe_oiiai APEdist_aaaa 6YL Type1 1093 - 1401 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 7R7KA 1.831 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out out-out TYR APEdihe_oiiai APEdist_aaaa 25J Type1 1094 - 1400 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 7R7RA 1.935 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out out-out TYR APEdihe_oiiai APEdist_aaaa AWJ Type1 1093 - 1401 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4FNZA 2.6 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in none-out TYR APEdihe_oiiai APEdist_aaaa NZF Type1 1093 - 1402 0 None C1097S ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 5IUIA 1.88 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in out-out TYR APEdihe_oiiai APEdist_aaaa 45Q Type1 1089 - 1400 0 None C1097S ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4FODA 2.0 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in out-out TYR APEdihe_oiiai APEdist_aaaa 0UV Type1 1085 - 1405 0 None C1097S ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 3AOXA 1.75 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in out-out TYR APEdihe_oiiai APEdist_aaaa EMH Type1 1086 - 1401 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 5A9UA 1.6 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out out-out TYR APEdihe_oiiai APEdist_aaaa 5P8 Type1 1093 - 1402 0 None C1156Y ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 5AACA 1.7 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out out-out TYR APEdihe_oiiai APEdist_aaaa VGH Type1 1093 - 1402 0 None C1156Y ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 7BTTA 1.86 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in out-out TYR APEdihe_oiiai APEdist_aaaa F8R Type1 1093 - 1401 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4FOBA 1.9 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in out-out TYR APEdihe_oiiai APEdist_aaaa 0US Type1 1093 - 1402 0 None C1097S ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4FOCA 1.7 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in out-out TYR APEdihe_oiiai APEdist_aaaa 0UU Type1 1093 - 1402 0 None C1097S ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4Z55A 1.55 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in out-out TYR APEdihe_oiiai APEdist_aaaa 4LO Type1 1093 - 1399 0 None S1281G ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 3LCSA 1.95 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in out-out TYR APEdihe_oiiai APEdist_aaaa STU Type1 1096 - 1399 0 None S1281G ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4MKCA 2.01 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in out-out TYR APEdihe_oiiai APEdist_aaaa 4MK Type1 1093 - 1401 0 None S1281G ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 9GBEA 1.58 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in out-out TYR APEdihe_oiiai APEdist_aaaa A1IJ8 Type1 1086 - 1401 0 None L1196M,G1202R ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4CNHB 1.9 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in out-out TYR APEdihe_oiiai APEdist_aaaa 3U9, 3U9 Type1, Allosteric 1093 - 1401 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4JOAA 2.7 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out out-out TYR APEdihe_oiiai APEdist_aaaa 3DK Type1.5_Front 1107 - 1398 0 None S1281G ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN AF-Q9UM73-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 1108 - 1393 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN AF-Q9UM73-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 1108 - 1393 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 2YJRA 1.9 Inactive DFGin‑None DFGAsp-rot-out in-in none-out TYR APEdihe_oiiai APEdist_aaaa No_ligand No_ligand 1101 - 1402 0 None F1174L ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 6EDLA 2.799 Inactive DFGin‑None DFGAsp-rot-in in-in none-out TYR APEdihe_oiiai APEdist_aaaa J4M Type1 1093 - 1399 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 5IMXA 2.12 Inactive DFGin‑None DFGAsp-rot-in in-in out-out TYR APEdihe_oiiai APEdist_aaaa CZ4 Type1 1109 - 1400 0 None None ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4DCEA 2.03 Inactive DFGin‑None DFGAsp-rot-in in-in none-out TYR APEdihe_oiiai APEdist_aaaa 0JF Type1 1093 - 1402 0 None C1097S ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4DCEB 2.03 Inactive DFGin‑None DFGAsp-rot-in in-in none-out TYR APEdihe_oiiai APEdist_aaaa 0JF Type1 1094 - 1402 0 None C1097S ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 5IUGA 1.93 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-out TYR APEdihe_oiiai APEdist_aaaa 729 Type2 1093 - 1404 0 None C1097S ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 5IUHA 2.1 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-out TYR APEdihe_oiiai APEdist_aaaa 34Y Type2 1093 - 1404 0 None C1097S ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4FNYA 2.45 Inactive DFGout‑None DFGAsp-rot-in in-in none-out TYR APEdihe_oiiai APEdist_aaaa I3K Type2 1103 - 1404 0 None C1097S,R1275Q ALK tyrosine kinase receptor
TYR AXL UFO_HUMAN AF-P30530-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 528 - 813 0 None None Tyrosine-protein kinase receptor UFO
TYR AXL UFO_HUMAN AF-P30530-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 528 - 813 0 None None Tyrosine-protein kinase receptor UFO
TYR AXL UFO_HUMAN 5U6BB 2.84 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa 7YS Type1 514 - 811 0 None None Tyrosine-protein kinase receptor UFO
TYR AXL UFO_HUMAN 5U6BD 2.84 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 7YS Type1 514 - 811 0 None None Tyrosine-protein kinase receptor UFO
TYR AXL UFO_HUMAN 5U6BA 2.84 Inactive DFGin‑None DFGAsp-rot-in out-out out-none TYR APEdihe_nnnai APEdist_aaaa 7YS Type1 521 - 813 0 None None Tyrosine-protein kinase receptor UFO
TYR AXL UFO_HUMAN 5U6BC 2.84 Inactive DFGin‑None DFGAsp-rot-in out-out out-none TYR APEdihe_nnnai APEdist_aaaa 7YS Type1 521 - 813 0 None None Tyrosine-protein kinase receptor UFO
TYR BLK BLK_HUMAN AF-P51451-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 233 - 500 0 None None Tyrosine-protein kinase Blk
TYR BLK BLK_HUMAN AF-P51451-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 233 - 500 0 None None Tyrosine-protein kinase Blk
TYR BMX BMX_HUMAN AF-P51813-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 409 - 675 0 None None Cytoplasmic tyrosine-protein kinase BMX
TYR BMX BMX_HUMAN AF-P51813-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 409 - 675 0 None None Cytoplasmic tyrosine-protein kinase BMX
TYR BMX BMX_HUMAN 8X2AA 1.3 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa LTJ Type1 411 - 671 0 None None Cytoplasmic tyrosine-protein kinase BMX
TYR BMX BMX_HUMAN 3SXRA 2.4 Inactive DFGinter‑BABtrans DFGAsp-rot-out out-out in-in TYR APEdihe_iiiai APEdist_aaaa 1N1 Type1 411 - 671 0 None Q432K,Q611M,D617T,Q620E Cytoplasmic tyrosine-protein kinase BMX
TYR BMX BMX_HUMAN 3SXRB 2.4 Inactive DFGinter‑BABtrans DFGAsp-rot-out out-out in-in TYR APEdihe_iiiai APEdist_aaaa 1N1 Type1 411 - 671 0 None Q432K,Q611M,D617T,Q620E Cytoplasmic tyrosine-protein kinase BMX
TYR BMX BMX_HUMAN 3SXSA 1.89 Inactive DFGinter‑BABtrans DFGAsp-rot-out out-out in-in TYR APEdihe_iiiai APEdist_aaaa PP2 Type1 411 - 671 0 None Q432K,Q611M,D617T,Q620E Cytoplasmic tyrosine-protein kinase BMX
TYR BMX BMX_HUMAN 6I99A 2.001 Inactive DFGinter‑BABtrans DFGAsp-rot-out out-out in-in TYR APEdihe_iiiai APEdist_aaaa H88 Type1 411 - 671 0 None Q432K,Q611M,D617T,Q620E Cytoplasmic tyrosine-protein kinase BMX
TYR BMX BMX_HUMAN 6I99B 2.001 Inactive DFGinter‑BABtrans DFGAsp-rot-out out-out in-in TYR APEdihe_iiiai APEdist_aaaa H88 Type1 411 - 671 0 None Q432K,Q611M,D617T,Q620E Cytoplasmic tyrosine-protein kinase BMX
TYR BTK BTK_HUMAN AF-Q06187-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 394 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN AF-Q06187-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 394 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 1K2PA 2.1 Inactive DFGin‑BLAplus DFGAsp-rot-out out-out in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 397 - 654 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 3K54A 1.94 Inactive DFGin‑BLAplus DFGAsp-rot-out in-out none-none TYR APEdihe_nniai APEdist_aaaa 1N1 Type1 392 - 658 0 None Y551E Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 3PIZA 2.21 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nniai APEdist_aaaa 03C Type1 391 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 3PJ1A 2.0 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nniai APEdist_aaaa LHL, LHL Type1, Allosteric 391 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 1K2PB 2.1 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out in-out TYR APEdihe_iioao APEdist_aaaa No_ligand No_ligand 397 - 654 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 8YVVA 2.25 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-out TYR APEdihe_oiiai APEdist_aaaa No_ligand No_ligand 394 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 8YVVB 2.25 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nnnai APEdist_aaaa No_ligand No_ligand 395 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 3P08A 2.3 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa No_ligand No_ligand 394 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 3P08B 2.3 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa No_ligand No_ligand 395 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6W8IA 3.8 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-none TYR APEdihe_niiai APEdist_aaaa No_ligand No_ligand 393 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6W8IB 3.8 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa No_ligand No_ligand 395 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 4NWMA 2.03 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-out TYR APEdihe_oiiai APEdist_aaaa 2P5 Type1 396 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 4NWMB 2.03 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-out TYR APEdihe_oiiai APEdist_aaaa 2P5 Type1 396 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6AUBA 1.65 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa BXM Type1 395 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6S90A 1.82 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa L0Z Type1 395 - 656 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6S90B 1.82 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa L0Z Type1 395 - 656 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5BPYA 2.31 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 4UQ Type1 396 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5BPYB 2.31 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-out TYR APEdihe_nooai APEdist_aaaa 4UQ Type1 396 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5JRSA 1.97 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 6MV Type1 396 - 656 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5JRSB 1.97 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-out TYR APEdihe_nooai APEdist_aaaa 6MV Type1 396 - 655 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5T18A 1.5 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 73T Type1 396 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7KXNA 1.34 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa X9P Type1 394 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7KXOA 1.94 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa X9S Type1 395 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7LTYA 1.69 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa YD7 Type1 393 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7LTZA 1.53 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa YDA Type1 394 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7KXLA 1.84 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa X9J Type1 392 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5ZZ4A 2.9 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-out TYR APEdihe_oiiai APEdist_aaaa 9M3 Type1 395 - 655 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5ZZ4B 2.9 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 9M3 Type1 393 - 655 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5ZZ4C 2.9 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-out TYR APEdihe_oiiai APEdist_aaaa 9M3 Type1 394 - 655 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5ZZ4D 2.9 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-out TYR APEdihe_oiiai APEdist_aaaa 9M3 Type1 393 - 655 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5ZZ4E 2.9 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 9M3 Type1 394 - 655 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5ZZ4F 2.9 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-out TYR APEdihe_oiiai APEdist_aaaa 9M3 Type1 393 - 655 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6O8IA 1.42 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa LTJ Type1 391 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7N4QA 1.5 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 0B9 Type1 392 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7N4RA 1.62 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa 0BG Type1 393 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7N4SA 2.05 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 0B0 Type1 394 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 4RX5A 1.356 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 3YO Type1 394 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5KUPA 1.389 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 6XL Type1 394 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5VGOA 1.621 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 9B1 Type1 394 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7KXQA 1.38 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa X9Y Type1 390 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 3OCSA 1.8 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-out TYR APEdihe_oiiai APEdist_aaaa 746 Type1 395 - 656 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 4OTFA 1.95 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 2VL Type1 396 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 4ZLYA 1.65 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 4RU Type1 389 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 4ZLZA 2.0 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 4RV Type1 389 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 8GC7A 1.9 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa YXJ Type1 389 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 8U2DA 1.95 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa UQX Type1 389 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 8U2EA 1.9 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa UP9 Type1 389 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5U9DA 1.33 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 83P Type1 389 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5VFIA 1.59 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 9AJ Type1 389 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6DI0A 1.3 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa GJG Type1 389 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6DI1A 1.1 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa GJD Type1 389 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6DI9A 1.25 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-none TYR APEdihe_niiai APEdist_aaaa GJJ Type1 392 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6NFHA 1.4 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa KLM Type1 389 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7KXMA 1.33 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa X9M Type1 389 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7KXPA 1.83 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa X9V Type1 389 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 3PIXA 1.85 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa 027 Type1 391 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5J87A 1.59 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa N42 Type1 396 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5J87B 1.59 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa N42 Type1 385 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5J87C 1.59 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa N42 Type1 396 - 656 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5J87D 1.59 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa N42 Type1 396 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6TFPA 2.0 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa N6Z Type1 393 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6TFPB 2.0 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa N6Z Type1 385 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6TFPC 2.0 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-out TYR APEdihe_oiiai APEdist_aaaa N6Z Type1 394 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6TFPD 2.0 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-out TYR APEdihe_oiiai APEdist_aaaa N6Z Type1 392 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6TFPE 2.0 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-out TYR APEdihe_oiiai APEdist_aaaa N6Z Type1 394 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5P9FA 1.71 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 2VL Type1 394 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5P9GA 1.75 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 7G6 Type1 394 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5P9HA 1.95 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-out TYR APEdihe_oiiai APEdist_aaaa 7G7 Type1 395 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5P9KA 1.28 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 7G8 Type1 389 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5P9LA 1.25 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-none TYR APEdihe_niiai APEdist_aaaa 7G9 Type1 392 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6AUAA 1.66 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa BXJ Type1 394 - 656 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6NZMA 1.72 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-out TYR APEdihe_oiiai APEdist_aaaa L9S Type1 395 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6NZMD 1.72 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-out TYR APEdihe_oiiai APEdist_aaaa L9S Type1 395 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5BQ0A 1.57 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa 4US Type1 389 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 8FLHA 1.55 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa Y8H Type1 392 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 8FLVA 1.3 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa ZB9 Type1 393 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 8TU3A 1.7 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa UEO Type1 394 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 8TU4A 1.6 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa V72 Type1 394 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 8TU5A 2.1 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-none TYR APEdihe_nniai APEdist_aaaa V7I Type1 395 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 4Z3VA 1.6 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 4L6 Type1 389 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7N5OA 1.25 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 0BQ Type1 389 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7N5RA 1.55 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 0UW Type1 389 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7N5XA 1.6 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 0GW Type1 389 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7N5YA 1.85 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 0CI Type1 389 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6BIKA 1.901 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-out TYR APEdihe_oiiai APEdist_aaaa DTJ Type1 395 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6BKEA 1.95 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-out TYR APEdihe_oiiai APEdist_aaaa DVJ Type1 395 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6BKHA 1.792 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-out TYR APEdihe_oiiai APEdist_aaaa DVD Type1 396 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6BLNA 1.3 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-out TYR APEdihe_oiiai APEdist_aaaa DY4 Type1 395 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6XE4A 1.6 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa V1G Type1 395 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6VXQA 1.4 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa RQS Type1 392 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6W06A 1.55 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa S5M Type1 393 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6W07A 1.51 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa S9A Type1 393 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 8FLGA 2.2 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa Y8C Type1 395 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 4OT5A 1.55 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 481 Type1 396 - 658 0 None M489A,R492A,E624A,K625A Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 4OT6A 2.05 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 2V1 Type1 394 - 658 0 None M489A,R492A,E624A,K625A Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 4OTQA 1.55 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 2V2 Type1 396 - 658 0 None M489A,R492A,E624A,K625A Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 4OTRA 1.95 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 2V3 Type1 396 - 658 0 None M489A,R492A,E624A,K625A Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 4RFYA 1.7 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 3OU Type1 396 - 658 0 None M489A,R492A,E624A,K625A Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 4RFZA 1.17 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 3OV Type1 396 - 658 0 None M489A,R492A,E624A,K625A Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 4RG0A 2.5 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 3P0 Type1 396 - 658 0 None M489A,R492A,E624A,K625A Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6EP9A 2.01 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa BNB Type1 396 - 658 0 None M489A,R492A,E624A,K625A Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6HRPA 1.12 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa GMQ Type1 396 - 658 0 None M489A,R492A,E624A,K625A Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6HRTA 1.36 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa GMW Type1 396 - 658 0 None M489A,R492A,E624A,K625A Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 8GC8A 1.75 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none none-none TYR APEdihe_niiai APEdist_aaaa YXJ Type1 392 - 658 0 None L528W Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 8EJBA 1.58 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa WKC, PD Type1, Allosteric 389 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6X3NA 1.95 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_niiai APEdist_aaaa ULV, 5WE Type1, Allosteric 392 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6BKWA 1.499 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa DXM, FPZ Type1, Type1 393 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6J6MA 1.25 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa BA0 Type1.5_Back 393 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7R61A 1.52 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 2IJ Type1.5_Back 390 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6DI3A 2.0 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa GJA Type1.5_Back 393 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6DI5A 1.42 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa GJ7 Type1.5_Back 389 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6N9PA 2.23 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa KHD Type1.5_Back 389 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6OMUA 1.41 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa MZJ Type1.5_Back 389 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7L5OA 1.21 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa R1L Type1.5_Back 389 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7L5PA 2.14 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa R1L Type1.5_Back 392 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7L5PB 2.14 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa R1L Type1.5_Back 393 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7R60A 1.94 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 2IE Type1.5_Back 389 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 8E2MA 1.904 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa UB6 Type1.5_Back 389 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6W7OA 2.17 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa TL7 Type1.5_Back 396 - 656 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6W7OB 2.17 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa TL7 Type1.5_Back 396 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6W8IC 3.8 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa TKY Type1.5_Back 395 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 8DSOB 2.334 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-out TYR APEdihe_iooai APEdist_aaaa TOO Type1.5_Back 392 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 4YHFA 2.2 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-out TYR APEdihe_oiiai APEdist_aaaa 4C9 Type1.5_Back 391 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 4YHFB 2.2 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 4C9 Type1.5_Back 390 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5P9IA 1.11 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 1E8 Type1.5_Back 389 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5P9JA 1.08 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 8E8 Type1.5_Back 394 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5P9MA 1.41 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 7GB Type1.5_Back 389 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 3GENA 1.6 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa B43 Type1.5_Back 392 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6E4FA 1.15 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa HRA Type1.5_Back 389 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5FBOA 1.894 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-out TYR APEdihe_oiiai APEdist_aaaa 5WH, 5WE Type1.5_Back, Allosteric 392 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 8FLNA 1.334 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa Y7W, BTB Type1.5_Front, Allosteric 395 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5FBNC 1.8 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 5WF, 5WE Type1.5_Front, Allosteric 395 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6X3OA 1.9 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa ULY, 5WE Type1.5_Front, Allosteric 395 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6X3OB 1.9 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa ULY, 5WE Type1.5_Front, Allosteric 393 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 8FLLA 1.498 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-out TYR APEdihe_oiiai APEdist_aaaa Y7W, BTB Type1.5_Front, Allosteric 395 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5FBND 1.8 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa 5WF, 5WE, 5WE, 5WE Type1.5_Front, Allosteric, Allosteric, Allosteric 394 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6X3PA 1.34 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa UM4, UM4, BTB Type1.5_Front, Allosteric, Type1 394 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 3PIYA 2.55 Inactive DFGin‑None DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 585 Type1 391 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 3PJ2A 1.75 Inactive DFGin‑None DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa 04K Type1.5_Back 391 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5XYZA 2.64 Inactive DFGinter‑BABtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa GYL Type1 394 - 656 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5XYZB 2.64 Inactive DFGinter‑BABtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa GYL Type1 394 - 656 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7YC9A 1.4 Inactive DFGinter‑BABtrans DFGAsp-rot-out out-out out-in TYR APEdihe_iiiai APEdist_aaaa IS4 Type1 395 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 3OCTA 1.95 Inactive DFGinter‑BABtrans DFGAsp-rot-out in-out out-none TYR APEdihe_nniai APEdist_aaaa 1N1 Type1 394 - 656 0 None V555R Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6NFIA 2.41 Inactive DFGinter‑None DFGAsp-rot-out out-out none-none TYR APEdihe_niiai APEdist_aaaa KLP Type1 392 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 3PJ3A 1.85 Inactive None‑None DFGAsp-rot-out in-in none-none TYR APEdihe_nniai APEdist_aaaa 04L Type1 391 - 659 0 None None Tyrosine-protein kinase BTK
TYR CSF1R CSF1R_HUMAN AF-P07333-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 574 - 920 0 None None Macrophage colony-stimulating factor 1 receptor
TYR CSF1R CSF1R_HUMAN AF-P07333-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 574 - 920 0 None None Macrophage colony-stimulating factor 1 receptor
TYR CSF1R CSF1R_HUMAN 3LCDA 2.5 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa BDY Type1 558 - 913 0 None None Macrophage colony-stimulating factor 1 receptor
TYR CSF1R CSF1R_HUMAN 8CGCA 1.925 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa LMR, UIK Allosteric, Type1 547 - 919 0 None None Macrophage colony-stimulating factor 1 receptor
TYR CSF1R CSF1R_HUMAN 3BEAA 2.02 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa IXH Type1 547 - 921 0 None A933L Macrophage colony-stimulating factor 1 receptor
TYR CSF1R CSF1R_HUMAN 2I1MA 1.8 Inactive DFGout‑BBAminus DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa 5CN Type1 547 - 921 0 None None Macrophage colony-stimulating factor 1 receptor
TYR CSF1R CSF1R_HUMAN 8JOTA 1.69 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa UKI Type1 543 - 914 0 None C667T,C830S,C907T Macrophage colony-stimulating factor 1 receptor
TYR CSF1R CSF1R_HUMAN 8W1LA 2.26 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa A1AE3 Type1 563 - 914 0 None None Macrophage colony-stimulating factor 1 receptor
TYR CSF1R CSF1R_HUMAN 2I0VA 2.8 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 6C3 Type1 544 - 916 0 None None Macrophage colony-stimulating factor 1 receptor
TYR CSF1R CSF1R_HUMAN 2I0YA 1.9 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 5CN Type1 548 - 916 0 None None Macrophage colony-stimulating factor 1 receptor
TYR CSF1R CSF1R_HUMAN 3KRJA 2.1 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa KRJ Type1 544 - 914 0 None S686S Macrophage colony-stimulating factor 1 receptor
TYR CSF1R CSF1R_HUMAN 3KRLA 2.4 Inactive DFGout‑BBAminus DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa KRL Type1 545 - 912 0 None S686S Macrophage colony-stimulating factor 1 receptor
TYR CSF1R CSF1R_HUMAN 7TNHA 2.7 Inactive DFGout‑BBAminus DFGAsp-rot-in in-none out-in TYR APEdihe_iiiai APEdist_aaaa I9W Type1 445 - 912 0 None None Macrophage colony-stimulating factor 1 receptor
TYR CSF1R CSF1R_HUMAN 6T2WA 1.7 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa M9T Type1 547 - 916 0 None None Macrophage colony-stimulating factor 1 receptor
TYR CSF1R CSF1R_HUMAN 3DPKA 1.95 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-none TYR APEdihe_niiai APEdist_aaaa 8C5 Type1.5_Back 548 - 912 0 None None Macrophage colony-stimulating factor 1 receptor
TYR CSF1R CSF1R_HUMAN 4HW7A 2.9 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 64M Type2 566 - 914 0 None C667T,C830S,C907T Macrophage colony-stimulating factor 1 receptor
TYR CSF1R CSF1R_HUMAN 4R7HA 2.8 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa P31 Type2 544 - 915 0 None C667T,C830S,C907T Macrophage colony-stimulating factor 1 receptor
TYR CSF1R CSF1R_HUMAN 4R7IA 2.75 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa STI Type2 567 - 914 0 None C667T,C830S,C907T Macrophage colony-stimulating factor 1 receptor
TYR CSF1R CSF1R_HUMAN 6N33A 2.25 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 622 Type2 566 - 915 0 None C667T,C830S,C907T Macrophage colony-stimulating factor 1 receptor
TYR CSF1R CSF1R_HUMAN 7MFCA 2.8 Inactive DFGout‑BBAminus DFGAsp-rot-in in-none out-in TYR APEdihe_iiiai APEdist_aaaa Z6V Type2 567 - 913 0 None C667T,C830S,C907T Macrophage colony-stimulating factor 1 receptor
TYR CSF1R CSF1R_HUMAN 6WXJA 2.62 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-none TYR APEdihe_nniai APEdist_aaaa UF4 Type2 559 - 917 0 None None Macrophage colony-stimulating factor 1 receptor
TYR CSF1R CSF1R_HUMAN 3LCOA 3.4 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-none TYR APEdihe_niiai APEdist_aaaa LC0 Type2 551 - 915 0 None None Macrophage colony-stimulating factor 1 receptor
TYR CSF1R CSF1R_HUMAN 6IG8A 1.8 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa A7O Type2 550 - 916 0 None S688A Macrophage colony-stimulating factor 1 receptor
TYR CSF1R CSF1R_HUMAN 2OGVA 2.7 Inactive DFGout‑None DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 543 - 918 0 None None Macrophage colony-stimulating factor 1 receptor
TYR CSK CSK_HUMAN 3D7UA 4.111 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa No_ligand No_ligand 188 - 450 0 None None Tyrosine-protein kinase CSK
TYR CSK CSK_HUMAN 3D7UC 4.111 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa No_ligand No_ligand 188 - 450 0 None None Tyrosine-protein kinase CSK
TYR CSK CSK_HUMAN AF-P41240-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 187 - 450 0 None None Tyrosine-protein kinase CSK
TYR CSK CSK_HUMAN AF-P41240-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 187 - 450 0 None None Tyrosine-protein kinase CSK
TYR CSK CSK_HUMAN 3D7TA 2.899 Inactive DFGin‑None DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa STU Type1 188 - 450 0 None K361A,K362A Tyrosine-protein kinase CSK
TYR CSK CSK_HUMAN 1BYGA 2.4 Inactive DFGinter‑BABtrans DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa STU Type1 187 - 448 0 None None Tyrosine-protein kinase CSK
TYR DDR1 DDR1_HUMAN AF-Q08345-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 602 - 913 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN AF-Q08345-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 602 - 913 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 6Y23A 2.58 Inactive DFGinter‑None DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 574 - 907 0 None Y569F,Y586F Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 6Y23B 2.58 Inactive DFGinter‑None DFGAsp-rot-out in-out out-none TYR APEdihe_niiai APEdist_aaaa No_ligand No_ligand 574 - 910 0 None Y569F,Y586F Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 6Y23C 2.58 Inactive DFGinter‑None DFGAsp-rot-out in-out out-none TYR APEdihe_niiai APEdist_aaaa No_ligand No_ligand 574 - 911 0 None Y569F,Y586F Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 6BRJA 2.231 Inactive DFGinter‑None DFGAsp-rot-out in-in out-in TYR APEdihe_iiiai APEdist_aaaa VX6 Type1 605 - 913 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 6BSDA 2.606 Inactive DFGinter‑None DFGAsp-rot-out in-in out-in TYR APEdihe_iiiai APEdist_aaaa 1N1 Type1 604 - 912 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 5SAUA 1.8 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 1IF Type2 604 - 912 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 5SAVA 1.76 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 1IJ Type2 602 - 909 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 5SAWA 1.601 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 1IM Type2 603 - 907 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 5SAXA 1.902 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 1IM Type2 601 - 913 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 5SAYA 2.19 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 1IJ Type2 602 - 907 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 5SAYB 2.19 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 1IJ Type2 602 - 911 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 5SAZA 1.8 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 1IW Type2 603 - 913 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 5SB0A 1.97 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 1IZ Type2 604 - 913 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 5SB1A 1.53 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 1JI Type2 604 - 913 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 6FEWA 1.44 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa D6W Type2 603 - 911 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 6FEXA 1.291 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa D6Z Type2 602 - 908 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 6FILA 1.73 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa D6W Type2 604 - 912 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 6FINA 1.67 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa DJQ Type2 603 - 911 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 6FIOA 1.99 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa DJH Type2 598 - 912 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 6FIQA 1.79 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-out TYR APEdihe_oiiai APEdist_aaaa DJW Type2 601 - 913 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 3ZOSB 1.92 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 0LI Type2 601 - 913 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 4BKJA 1.7 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa STI Type2 601 - 913 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 4BKJB 1.7 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa STI Type2 601 - 913 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 4CKRA 2.2 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-none TYR APEdihe_niiai APEdist_aaaa DI1 Type2 601 - 913 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 6GWRA 2.07 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa FEW Type2 601 - 912 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 6GWRB 2.07 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa FEW Type2 602 - 908 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 6HP9A 1.96 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa GKB Type2 601 - 909 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 6HP9B 1.96 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa GKB Type2 603 - 909 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 7BCMA 2.3 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa TBK Type2 604 - 909 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 7BCMB 2.3 Inactive DFGout‑BBAminus DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa TBK Type2 604 - 911 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 7BE6A 1.871 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa TJW Type2 601 - 912 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 5BVNA 2.21 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 4VD Type2 604 - 911 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 5BVOA 1.98 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 4VE Type2 604 - 911 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 5FDPA 2.25 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 5WR Type2 604 - 912 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 5FDXA 2.65 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 5X1 Type2 604 - 909 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 5FDXB 2.65 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 5X1 Type2 605 - 907 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 3ZOSA 1.92 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 0LI, 0LI Type2, Allosteric 602 - 913 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 7FEHA 1.61 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 3UI Type3 603 - 912 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 5BVWA 1.94 Inactive DFGout‑None DFGAsp-rot-out in-in none-in TYR APEdihe_iiiai APEdist_aaaa 1N1 Type1 604 - 911 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 5SB2A 1.6 Inactive DFGout‑None DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 1K2 Type2 603 - 912 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 5BVKA 2.29 Inactive DFGout‑None DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 4VC Type3 604 - 911 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR2 DDR2_HUMAN AF-Q16832-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 555 - 855 0 None None Discoidin domain-containing receptor 2
TYR DDR2 DDR2_HUMAN AF-Q16832-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 555 - 855 0 None None Discoidin domain-containing receptor 2
TYR DDR2 DDR2_HUMAN 6FERD 2.87 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa D6Q Type1 553 - 851 0 None None Discoidin domain-containing receptor 2
TYR DDR2 DDR2_HUMAN 6FERI 2.87 Inactive DFGout‑BBAminus DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa D6Q Type1 555 - 851 0 None None Discoidin domain-containing receptor 2
TYR DDR2 DDR2_HUMAN 6FERA 2.87 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa D6Q Type2 553 - 851 0 None None Discoidin domain-containing receptor 2
TYR DDR2 DDR2_HUMAN 6FERB 2.87 Inactive DFGout‑BBAminus DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa D6Q Type2 553 - 851 0 None None Discoidin domain-containing receptor 2
TYR DDR2 DDR2_HUMAN 6FERC 2.87 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa D6Q Type2 553 - 851 0 None None Discoidin domain-containing receptor 2
TYR DDR2 DDR2_HUMAN 6FERE 2.87 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa D6Q Type2 553 - 851 0 None None Discoidin domain-containing receptor 2
TYR DDR2 DDR2_HUMAN 6FERF 2.87 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa D6Q Type2 553 - 851 0 None None Discoidin domain-containing receptor 2
TYR DDR2 DDR2_HUMAN 6FERG 2.87 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa D6Q Type2 553 - 851 0 None None Discoidin domain-containing receptor 2
TYR DDR2 DDR2_HUMAN 6FERH 2.87 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa D6Q Type2 553 - 851 0 None None Discoidin domain-containing receptor 2
TYR DDR2 DDR2_HUMAN 6FERJ 2.87 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa D6Q Type2 553 - 851 0 None None Discoidin domain-containing receptor 2
TYR DDR2 DDR2_HUMAN 6FERK 2.87 Inactive DFGout‑BBAminus DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa D6Q Type2 555 - 851 0 None None Discoidin domain-containing receptor 2
TYR DDR2 DDR2_HUMAN 6FERL 2.87 Inactive DFGout‑BBAminus DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa D6Q Type2 554 - 851 0 None None Discoidin domain-containing receptor 2
TYR DDR2 DDR2_HUMAN 7AYMA 2.12 Inactive DFGout‑BBAminus DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa 4VD Type2 558 - 849 0 None K826E,L847R Discoidin domain-containing receptor 2
TYR EGFR EGFR_HUMAN 3IKAA 2.9 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 0UN Type1 696 - 1020 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7ER2A 2.662 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa JAU Type1 697 - 1018 0 None T790M,C797S Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9XU9A 2.84 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1E1C Type1 696 - 1020 0 None T790M,C797S,L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8KFQA 3.22 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa VUZ Type1 697 - 1018 0 None T790M,L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4LL0A 4.0 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out in-none TYR APEdihe_nniai APEdist_aaaa YUN Type1 697 - 1017 0 None T790M,L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4LL0B 4.0 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out in-none TYR APEdihe_nniai APEdist_aaaa YUN Type1 698 - 1017 0 None T790M,L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3VJNA 2.34 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-in TYR APEdihe_iiiai APEdist_aaaa ANP ATPlike 697 - 1018 0 None G719S,T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8DSWA 2.39 Inactive DFGin‑BLAminus DFGAsp-rot-in none-none in-none TYR APEdihe_nniai APEdist_aaaa ANP ATPlike 696 - 1017 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2ITXA 2.98 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa ANP ATPlike 697 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3VJOA 2.64 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-in TYR APEdihe_iiiai APEdist_aaaa ANP ATPlike 696 - 1018 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2ITNA 2.47 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa ANP ATPlike 696 - 1019 0 None G719S Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2ITVA 2.47 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa ANP ATPlike 696 - 1019 0 None L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8HV4A 2.2 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa PE5, MWU Allosteric, Type1 696 - 1020 0 None E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8HV6A 2.2 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa PE5, N86 Allosteric, Type1 696 - 1020 0 None E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8HV7A 2.69 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa PE5, N8O Allosteric, Type1 696 - 1019 0 None E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8HV8A 2.4 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa PE5, N99 Allosteric, Type1 696 - 1019 0 None C797S,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8HV9A 2.5 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa PE5, N9L Allosteric, Type1 696 - 1019 0 None E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9BY6A 2.551 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa PDO, Q6K Allosteric, Type1 698 - 1009 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8HV1A 2.4 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa PE5, N6N Allosteric, Type1 696 - 1019 0 None E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8HV3A 2.4 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa PE5, MWU Allosteric, Type1 696 - 1020 0 None E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8HV5A 2.2 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa PE5, N7C Allosteric, Type1 696 - 1019 0 None E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9BY4A 2.307 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa PDO, Q6K, PDO, PDO Allosteric, Type1, Allosteric, Type1 696 - 1010 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2JITA 3.1 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 696 - 1016 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3UG1A 2.75 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 697 - 1018 0 None G719S,T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN AF-P00533-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 704 - 978 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN AF-P00533-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 704 - 978 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2J5EA 3.1 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa No_ligand No_ligand 696 - 1020 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2GS2A 2.8 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 696 - 1018 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2GS6A 2.6 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 696 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4WRGA 1.9 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-none TYR APEdihe_niiai APEdist_aaaa No_ligand No_ligand 696 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7SI1A 1.6 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 695 - 1020 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4TKSA 3.202 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 697 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 1M14A 2.6 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-out TYR APEdihe_oiiai APEdist_aaaa No_ligand No_ligand 696 - 1020 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2EB2A 2.5 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 696 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4R3PA 2.905 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 696 - 1018 0 None L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4R3RA 3.25 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 696 - 1018 0 None L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5CZHA 2.8 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 696 - 1018 0 None L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5CZIA 2.6 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 696 - 1018 0 None L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9U8CE 3.5 Inactive DFGin‑BLAminus DFGAsp-rot-in in-none in-out TYR APEdihe_oooao APEdist_aaaa No_ligand No_ligand 696 - 982 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8H7XA 3.404 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 6GY Type1 697 - 1019 0 None T790M,C797S Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5XGNA 3.0 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 85X Type1 697 - 1020 0 None T790M,C797S Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6JRXA 2.201 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 9JO Type1 696 - 1017 0 None T790M,C797S Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5J9YA 2.8 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 6HL Type1 697 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8EMEB 3.32 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out none-none TYR APEdihe_nnnai APEdist_aaaa ZNL Type1 702 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5J9ZA 2.5 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_nniai APEdist_aaaa 6HJ Type1 696 - 1020 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7A6IA 2.4 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-out TYR APEdihe_oiiai APEdist_aaaa R1W Type1 703 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2KA 3.201 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 0UN Type1 696 - 1020 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2JIUA 3.05 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-in TYR APEdihe_iiiai APEdist_aaaa AEE Type1 696 - 1016 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5FEQA 3.4 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_iioao APEdist_aaaa 5XH Type1 697 - 1017 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4G5PA 3.17 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 0WN Type1 696 - 1016 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5GMPA 2.797 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_nniai APEdist_aaaa F62 Type1 696 - 1019 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5GTZA 2.999 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_nioao APEdist_aaaa 81C Type1 697 - 1020 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5XDKA 2.346 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 8JC Type1 696 - 1018 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6JX4A 2.531 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa YY3 Type1 696 - 1018 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4WD5A 3.3 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-in TYR APEdihe_iiiai APEdist_aaaa 3LH Type1 694 - 1021 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5Y9TA 3.25 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 8RC Type1 697 - 1020 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3UG2A 2.5 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-in TYR APEdihe_iiiai APEdist_aaaa IRE Type1 697 - 1018 0 None G719S,T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7VRAA 2.41 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa I0A Type1 696 - 1018 0 None T790M,C797S Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7VREA 2.507 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa 7VH Type1 696 - 1018 0 None T790M,C797S Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6S89A 2.701 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa L0Q Type1 697 - 1017 0 None T790M,C797S,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6S8AA 2.6 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa L0N Type1 697 - 1018 0 None T790M,C797S,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7ZYMA 2.5 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 6GY Type1 696 - 1020 0 None T790M,C797S,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7ZYNA 2.3 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 0UN Type1 697 - 1018 0 None T790M,C797S,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7ZYPA 2.8 Inactive DFGin‑BLAminus DFGAsp-rot-out in-none in-in TYR APEdihe_iiiai APEdist_aaaa R25 Type1 695 - 1019 0 None T790M,C797S,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9JQ1A 3.02 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1ECU Type1 697 - 1020 0 None T790M,C797S,L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7OXBA 2.56 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 35Z Type1 696 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9KLWA 2.67 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa A1L53 Type1 696 - 1019 0 None T790M,L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9S3XA 2.423 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-in TYR APEdihe_iiiai APEdist_aaaa A1JLU Type1 696 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8WD4A 2.55 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa W7W Type1 696 - 1019 0 None T790M,C797S,L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6LUBA 2.315 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa EUX Type1 696 - 1018 0 None T790M,C797S,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6LUDA 2.05 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa YY3 Type1 696 - 1018 0 None T790M,C797S,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9D3VA 2.32 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_ooiai APEdist_aaaa A1A5V Type1 696 - 1019 0 None C797S,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9D3WA 2.53 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1A5L Type1 696 - 1017 0 None C797S,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8HVAA 2.77 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa N9R Type1 696 - 1020 0 None E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6JZ0A 2.86 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa CKO Type1 696 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2ITWA 2.88 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-in TYR APEdihe_iiiai APEdist_aaaa ITQ Type1 696 - 1018 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2ITYA 3.42 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_nniai APEdist_aaaa IRE Type1 697 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2J5FA 3.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa DJK Type1 696 - 1020 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2J6MA 3.1 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa AEE Type1 697 - 1020 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6VH4A 2.8 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa QQM Type1 696 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6VHNA 2.4 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa QQJ Type1 696 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6VHPA 3.6 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa QP1 Type1 696 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8G63A 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa YXT Type1 696 - 1017 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9DM8A 2.13 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa A1A6K Type1 696 - 1017 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9MSRA 1.93 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_nniai APEdist_aaaa A1BRC Type1 697 - 1017 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9MSSA 2.09 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1BYO Type1 697 - 1017 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9MSTA 2.57 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1BYN Type1 696 - 1017 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9NGPA 2.4 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa A1BX7 Type1 698 - 1018 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9NHWA 2.73 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa A1BYD Type1 698 - 1017 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9NISA 2.23 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa A1BYK Type1 696 - 1016 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9NJ7A 2.53 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa A1BYL Type1 698 - 1017 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9NJNA 2.24 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa A1BYS Type1 698 - 1017 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9NM0A 2.59 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa VO7 Type1 697 - 1018 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9OS6A 2.75 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa A1CEA Type1 697 - 1017 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9OU9A 2.1 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_nniai APEdist_aaaa A1CEL Type1 697 - 1017 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9PMZA 2.33 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_nniai APEdist_aaaa A1CI6 Type1 696 - 1017 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9Q0SA 2.46 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_niiai APEdist_aaaa A1CNG Type1 696 - 1017 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9H42A 2.601 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1IR8 Type1 696 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9H46A 3.163 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa A1ISA Type1 696 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9H47A 2.991 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1IR9 Type1 696 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7UKVA 2.4 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa ZRT Type1 696 - 1018 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5FEDA 2.651 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 5X4 Type1 697 - 1017 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7T4IA 2.61 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa R28 Type1 697 - 1017 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4JQ7A 2.73 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa KJQ Type1 696 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4JQ8A 2.83 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa KJ8 Type1 696 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4JR3A 2.7 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa KJR Type1 696 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4JRVA 2.8 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa KJV Type1 696 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4LI5A 2.64 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 1WY Type1 696 - 1020 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4I23A 2.8 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 1C9 Type1 695 - 1018 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5UGBA 2.53 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 8BM Type1 695 - 1018 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7AEIA 2.65 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa R85 Type1 697 - 1018 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8PNZA 2.51 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-in TYR APEdihe_iiiai APEdist_aaaa 2I0 Type1 695 - 1018 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9FZRA 1.991 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1IHC Type1 696 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9FZSA 2.121 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1IHD Type1 696 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5JEBA 3.298 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oioao APEdist_aaaa 6JS Type1 699 - 999 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4WKQA 1.85 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa IRE Type1 696 - 1020 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4ZAUA 2.8 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa YY3 Type1 698 - 1017 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8SC7A 1.984 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa D0D Type1 696 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9KL4A 2.32 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1L53 Type1 696 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5CAVA 2.73 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 4ZQ Type1 697 - 1020 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5EM8A 2.8 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 5Q4 Type1 696 - 1018 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7KXZA 2.4 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa XA4 Type1 696 - 1017 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7U99A 2.5 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa M0R Type1 695 - 1018 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7U9AA 2.6 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_niiai APEdist_aaaa M19 Type1 695 - 1018 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8F1HA 2.8 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa X9H Type1 697 - 1018 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8F1XA 2.3 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa R28 Type1 696 - 1018 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8F1YA 2.75 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa R2E Type1 696 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8TJLA 2.7 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa HZ6 Type1 696 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8HV2A 2.8 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa MWU Type1 697 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 1M17A 2.6 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa AQ4 Type1 696 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7B85A 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa R28 Type1 697 - 1020 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9GHRA 2.1 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1ILN Type1 697 - 1020 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9GHSA 2.6 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1ILJ Type1 697 - 1020 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9GHTA 2.6 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa XA4 Type1 697 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9GHUA 2.25 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1ILK Type1 697 - 1020 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9GHVA 2.5 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1ILI Type1 697 - 1018 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7AEMA 2.65 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 6GY Type1 695 - 1018 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2ITOA 3.25 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_nniai APEdist_aaaa IRE Type1 696 - 1019 0 None G719S Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2ITPA 2.74 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa AEE Type1 697 - 1018 0 None G719S Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2ITQA 2.68 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa ITQ Type1 697 - 1018 0 None G719S Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6S9BA 3.25 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa L1H Type1 697 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6S9CA 2.73 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa L1K Type1 696 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6S9DA 2.67 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa L3Z Type1 696 - 1017 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8HY7A 2.91 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-none TYR APEdihe_nniai APEdist_aaaa NSO Type1 696 - 1019 0 None E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4RJ4A 2.78 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 3QW Type1 697 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4RJ7A 2.55 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 3R1 Type1 697 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4RJ8A 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 3QS Type1 697 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5C8KA 3.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 4YV Type1 697 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5C8MA 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 4YW Type1 697 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5C8NA 2.401 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 4YX Type1 696 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5CALA 2.7 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 4Z8 Type1 697 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5CANA 2.8 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 4ZB Type1 696 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5CAOA 2.6 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa 4ZG Type1 697 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5CAPA 2.4 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 4ZH Type1 697 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5EM7A 2.81 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 5Q4 Type1 696 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5HCXA 2.6 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 60B Type1 696 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5HCZA 2.62 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 60E Type1 696 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5HIBA 2.85 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 63M Type1 696 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6JRKA 2.796 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-none TYR APEdihe_nniai APEdist_aaaa C6O Type1 696 - 1018 0 None E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2ITTA 2.73 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa AEE Type1 697 - 1019 0 None L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2ITUA 2.8 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-none TYR APEdihe_nniai APEdist_aaaa ITQ Type1 696 - 1019 0 None L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2ITZA 2.8 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-none TYR APEdihe_nniai APEdist_aaaa IRE Type1 697 - 1020 0 None L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X26A 2.951 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 7XO Type1 697 - 1020 0 None L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X27A 2.952 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 7XR Type1 697 - 1020 0 None L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X28A 2.952 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 7XU Type1 697 - 1020 0 None L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5XDLA 2.7 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa 8JC Type1 696 - 1018 0 None L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6JWLA 2.551 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa YY3 Type1 696 - 1020 0 None L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4LQMA 2.5 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa DJK Type1 697 - 1019 0 None L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7LGSA 3.1 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa Q6K Type1 702 - 984 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7LGSB 3.1 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa Q6K Type1 702 - 984 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7LGSC 3.1 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa Q6K Type1 701 - 984 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7LGSD 3.1 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa Q6K Type1 701 - 984 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7T4JA 2.2 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa R28 Type1 701 - 984 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7T4JB 2.2 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa R28 Type1 701 - 984 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8PO0A 2.523 Inactive DFGin‑BLAminus DFGAsp-rot-in in-none in-out TYR APEdihe_oiiai APEdist_aaaa 2I6 Type1 695 - 1018 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4LRMA 3.526 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa YUN Type1 696 - 999 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4LRMB 3.526 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa YUN Type1 695 - 984 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4LRMC 3.526 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa YUN Type1 694 - 983 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4LRMD 3.526 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa YUN Type1 696 - 981 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4LRME 3.526 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa YUN Type1 697 - 983 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9U8CA 3.5 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-out TYR APEdihe_oiiai APEdist_aaaa A1L8T Type1 696 - 989 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9U8CB 3.5 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1L8T Type1 696 - 986 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9U8CC 3.5 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-in TYR APEdihe_iiiai APEdist_aaaa A1L8T Type1 696 - 980 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9U8CD 3.5 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa A1L8T Type1 696 - 987 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6JX0A 2.53 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa YY3, YY3 Type1, Allosteric 701 - 989 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4G5JA 2.8 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 0WN, 0WM, 0WM Type1, Allosteric, Allosteric 696 - 1016 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8D73A 2.17 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa QCR Type1.5_Back 703 - 1011 0 None T790M,L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8D73B 2.17 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa QCR Type1.5_Back 704 - 1012 0 None T790M,L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8D76A 2.4 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa QFO Type1.5_Back 703 - 1014 0 None T790M,L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8D76B 2.4 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa QFO Type1.5_Back 702 - 1014 0 None T790M,L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6D8EA 2.537 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa FZP Type1.5_Back 696 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9GL9A 2.147 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1IMT Type1.5_Back 696 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9FRDA 2.06 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1IEZ Type1.5_Back 696 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9GI9A 3.12 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1ILZ Type1.5_Back 696 - 1018 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8F1ZA 2.4 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa X9B Type1.5_Back 695 - 1018 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9QXNAAA 2.142 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1JBI Type1.5_Back 696 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4RJ5A 3.1 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa 3QY Type1.5_Back 697 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5CAQA 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 4ZJ Type1.5_Back 697 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5CASA 2.1 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 4ZQ Type1.5_Back 696 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5CAUA 2.25 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 4ZR Type1.5_Back 696 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5HCYA 2.46 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 60D Type1.5_Back 696 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5HICA 2.6 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 63N Type1.5_Back 697 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4R5SA 3.001 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-out TYR APEdihe_nnoao APEdist_aaaa FI3 Type1.5_Back 697 - 1018 0 None L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9DF2A 2.5 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1IMS Type1.5_Back 701 - 1004 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9DF3A 1.68 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1IMS Type1.5_Back 701 - 1022 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9DF4A 1.78 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1A4E Type1.5_Back 701 - 1019 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9FQPA 2.495 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1IEZ Type1.5_Back 701 - 1020 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9FQSA 1.783 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1IE0 Type1.5_Back 701 - 1019 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9GL7A 1.878 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1IMS Type1.5_Back 702 - 1019 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9GL8A 1.632 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1IMT Type1.5_Back 701 - 1021 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3W2OA 2.35 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-in TYR APEdihe_iiiai APEdist_aaaa 03P Type1.5_Front 698 - 1017 0 None T790M,L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3W2PA 2.05 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-in TYR APEdihe_iiiai APEdist_aaaa W2P Type1.5_Front 698 - 1018 0 None T790M,L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3W2QA 2.2 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-in TYR APEdihe_iiiai APEdist_aaaa HKI Type1.5_Front 698 - 1017 0 None T790M,L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2EB3A 2.84 Inactive DFGin‑BLAplus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa ANP ATPlike 696 - 1018 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5EDPA 2.9 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_niiai APEdist_aaaa No_ligand No_ligand 697 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5XGMA 2.952 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_niiai APEdist_aaaa 85X Type1 696 - 1019 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6JRJA 2.943 Inactive DFGin‑BLAplus DFGAsp-rot-in in-out in-none TYR APEdihe_nnnai APEdist_aaaa C6O Type1 696 - 1018 0 None T790M,C797S,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5Y25A 3.102 Inactive DFGin‑BLAplus DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa 8LU Type1 698 - 1017 0 None T790M,L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5EDRA 2.6 Inactive DFGin‑BLAplus DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa 5N4 Type1 697 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5EM5A 2.65 Inactive DFGin‑BLAplus DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa 5Q2 Type1 697 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6TFUB 2.0 Inactive DFGin‑BLAplus DFGAsp-rot-out out-none none-none TYR APEdihe_nniai APEdist_aaaa N7K Type1.5_Back 700 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5EDQA 2.8 Inactive DFGin‑BLAplus DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa 5N3 Type1.5_Back 697 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8A27A 1.07 Inactive DFGin‑BLAplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa KY9 Type3 701 - 985 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8A2AA 1.43 Inactive DFGin‑BLAplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa KY9 Type3 700 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXIC 3.0 Inactive DFGin‑BLBminus DFGAsp-rot-in out-out none-none TYR APEdihe_nniai APEdist_aaaa 8BS Type1 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4RJ6A 2.7 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 3R0 Type1 697 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5EM6A 2.78 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 5Q3 Type1.5_Back 697 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8A2DA 1.11 Inactive DFGin‑BLBminus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa KXY Type3 701 - 1021 0 None L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6P1LB 2.8 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa ANP ATPlike 702 - 1008 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WAKA 2.4 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa ANP ATPlike 702 - 1013 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WAKD 2.4 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa ANP ATPlike 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8FV3A 2.1 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa ANP ATPlike 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8FV4C 2.2 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa ANP ATPlike 702 - 1013 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8TO3B 2.49 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa ANP ATPlike 702 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8TO4B 2.99 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa ANP ATPlike 702 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4ZSED 1.97 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa ANP ATPlike 701 - 1015 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5D41B 2.31 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa ANP ATPlike 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2AD 1.85 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa ANP ATPlike 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXKB 3.1 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa ANP ATPlike 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXMC 2.192 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa ANP ATPlike 702 - 1006 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5CNOB 1.55 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa ANP ATPlike 698 - 1015 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5CNNA 1.9 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa ANP ATPlike 699 - 1014 0 None I706Q Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6P1DB 2.4 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa ANP, NQ1 ATPlike, Type3 702 - 1013 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6P1LA 2.8 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa ANP, 9LL ATPlike, Type3 701 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6P1LC 2.8 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa ANP, 9LL ATPlike, Type3 702 - 1005 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6P1LD 2.8 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa ANP, 9LL ATPlike, Type3 702 - 1015 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6P8QA 1.9 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa ANP, O57 ATPlike, Type3 699 - 1019 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6P8QB 1.9 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa AMP, O57 ATPlike, Type3 698 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6P8QC 1.9 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-in TYR APEdihe_iiiai APEdist_aaaa AMP, O57 ATPlike, Type3 699 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6P8QD 1.9 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa AMP, O57 ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6XL4D 2.06 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa ANP, NQ1 ATPlike, Type3 700 - 1013 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8TO4C 2.99 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa ANP, IXR ATPlike, Type3 702 - 1013 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8TO4D 2.99 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa ANP, IXR ATPlike, Type3 702 - 1005 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5D41A 2.31 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa ANP, 57N ATPlike, Type3 698 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6DUKA 2.2 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa ANP, JBJ ATPlike, Type3 701 - 1006 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6DUKB 2.2 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa ANP, JBJ ATPlike, Type3 699 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6DUKC 2.2 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa ANP, JBJ ATPlike, Type3 699 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6DUKD 2.2 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa ANP, JBJ ATPlike, Type3 701 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6DUKE 2.2 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa ANP, JBJ ATPlike, Type3 698 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6DUKF 2.2 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa ANP, JBJ ATPlike, Type3 701 - 1009 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXKD 3.1 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa ANP, JBJ ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXMD 2.192 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa ANP, 9LL ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXPA 2.16 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa ANP, JBJ ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXPB 2.16 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa ANP, JBJ ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXPD 2.16 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa ANP, JBJ ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXPF 2.16 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa ANP, JBJ ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXQB 1.83 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa ANP, VNS ATPlike, Type3 701 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXQD 1.83 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa ANP, VNS ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7LTXA 2.3 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa ANP, YFA ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7LTXB 2.3 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa ANP, YFA ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7LTXC 2.3 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa ANP, YFA ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7LTXD 2.3 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa ANP, YFA ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8GB4A 2.59 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa ANP, YW5 ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8GB4B 2.59 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nnnai APEdist_aaaa ANP, YW5 ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8GB4C 2.59 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa ANP, YW5 ATPlike, Type3 700 - 1012 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8GB4D 2.59 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nnnai APEdist_aaaa ANP, YW5 ATPlike, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7K1IA 3.202 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa ANP, VNS ATPlike, Type3 700 - 1007 0 None L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WXNA 1.76 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa No_ligand No_ligand 699 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7UKWA 2.6 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa No_ligand No_ligand 702 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7TVDA 2.96 Inactive DFGin‑BLBplus DFGAsp-rot-out in-out none-none TYR APEdihe_nniai APEdist_aaaa No_ligand No_ligand 698 - 1009 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5ZTOA 2.649 Inactive DFGin‑BLBplus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa 9JO Type1 697 - 1017 0 None T790M,C797S Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V66D 1.79 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa QP1 Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6KA 2.2 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa QQJ Type1 700 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6KC 2.2 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa QQJ Type1 700 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6KD 2.2 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa QQJ Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6KF 2.2 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa QQJ Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6KG 2.2 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa QQJ Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6OC 2.1 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa QQM Type1 701 - 1011 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6OD 2.1 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa QQM Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6OE 2.1 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa QQM Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6OH 2.1 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa QQM Type1 700 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V5NA 2.4 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa QP7 Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V5PA 2.3 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa QP4 Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXLB 2.4 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa VO7 Type1 700 - 1005 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXLC 2.4 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa VO7 Type1 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXLD 2.4 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nnnai APEdist_aaaa VO7 Type1 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7KY0A 3.1 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-none TYR APEdihe_nniai APEdist_aaaa XA4 Type1 701 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6TFYA 1.7 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_niiai APEdist_aaaa N7Z Type1 699 - 982 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7A6JB 2.0 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa R2E Type1 699 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7ZYQA 2.1 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-none TYR APEdihe_nniai APEdist_aaaa V58 Type1 700 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5FEEA 2.7 Inactive DFGin‑BLBplus DFGAsp-rot-in in-in in-out TYR APEdihe_iioao APEdist_aaaa 5X4 Type1 697 - 1018 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5GTYA 3.14 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa 816 Type1 700 - 1014 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5GTYC 3.14 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nnnai APEdist_aaaa 816 Type1 700 - 1013 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5GTYF 3.14 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-none TYR APEdihe_nniai APEdist_aaaa 816 Type1 700 - 1013 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6XL4A 2.06 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa Q6K, NQ1 Type1, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXKA 3.1 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa 8BS, JBJ Type1, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXKC 3.1 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa 8BS, JBJ Type1, Type3 701 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXKE 3.1 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa 8BS, JBJ Type1, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXKF 3.1 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa 8BS, JBJ Type1, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXMB 2.192 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa YY3, 9LL Type1, Type3 701 - 1012 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXWA 2.5 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa YY3, VNS Type1, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXWB 2.5 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nnnai APEdist_aaaa YY3, VNS Type1, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXWC 2.5 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa YY3, VNS Type1, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXWD 2.5 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa YY3, VNS Type1, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8GK5A 2.3 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa Q6K, YW5 Type1, Type3 701 - 1011 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8GK5B 2.3 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa Q6K, YW5 Type1, Type3 700 - 1008 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8GK5C 2.3 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa Q6K, YW5 Type1, Type3 700 - 1008 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8GK5D 2.3 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_niiai APEdist_aaaa Q6K, YW5 Type1, Type3 700 - 1008 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6Z4BA 2.5 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-none TYR APEdihe_niiai APEdist_aaaa Q6K, 9LL Type1, Type3 700 - 982 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6Z4BB 2.5 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa Q6K, 9LL Type1, Type3 699 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6Z4DB 2.0 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none none-none TYR APEdihe_niiai APEdist_aaaa 8BS, 57N Type1, Type3 700 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5GNKA 1.796 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa 80U Type1.5_Back 697 - 985 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WA2A 2.4 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa TOV Type1.5_Back 699 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WA2B 2.4 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa TOV Type1.5_Back 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WA2C 2.4 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa TOV Type1.5_Back 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WA2D 2.4 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa TOV Type1.5_Back 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8FV3C 2.1 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa YA6 Type1.5_Back 701 - 1009 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8FV4D 2.2 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa YAA Type1.5_Back 701 - 1005 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6TFUA 2.0 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa N7K Type1.5_Back 700 - 982 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6TFVA 1.5 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none none-none TYR APEdihe_niiai APEdist_aaaa N7Q Type1.5_Back 700 - 985 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6TFVB 1.5 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_niiai APEdist_aaaa N7Q Type1.5_Back 698 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6TFWA 2.0 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa N7W Type1.5_Back 700 - 982 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6TFWB 2.0 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa N7W Type1.5_Back 700 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6TFYB 1.7 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa N7Z Type1.5_Back 699 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6TFZA 1.8 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none none-none TYR APEdihe_niiai APEdist_aaaa N7B Type1.5_Back 701 - 982 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6TFZB 1.8 Inactive DFGin‑BLBplus DFGAsp-rot-in out-none out-none TYR APEdihe_nniai APEdist_aaaa N7B Type1.5_Back 700 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6TG0A 1.5 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out none-none TYR APEdihe_nniai APEdist_aaaa N78 Type1.5_Back 700 - 985 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6TG0B 1.5 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-none TYR APEdihe_niiai APEdist_aaaa N78 Type1.5_Back 698 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6TG1A 1.6 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa N82 Type1.5_Back 699 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6TG1B 1.6 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none none-none TYR APEdihe_nniai APEdist_aaaa N82 Type1.5_Back 698 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2JIVB 3.5 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_ooiai APEdist_aaaa HKI Type1.5_Back 699 - 982 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5GTYB 3.14 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa 816 Type1.5_Back 700 - 1014 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5GTYD 3.14 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa 816 Type1.5_Back 701 - 1014 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5GTYE 3.14 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-none TYR APEdihe_niiai APEdist_aaaa 816 Type1.5_Back 701 - 1014 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5GTYG 3.14 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa 816 Type1.5_Back 699 - 1014 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5GTYH 3.14 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa 816 Type1.5_Back 700 - 1016 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3W2RA 2.05 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-none TYR APEdihe_nniai APEdist_aaaa W2R Type1.5_Back 698 - 1017 0 None T790M,L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2RGPA 2.0 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-none TYR APEdihe_nniai APEdist_aaaa HYZ Type1.5_Back 702 - 1016 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3BELA 2.3 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-none TYR APEdihe_nniai APEdist_aaaa POX Type1.5_Back 702 - 1015 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8PO4A 1.621 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa 26X Type1.5_Back 700 - 1014 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3LZBA 2.7 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_niiai APEdist_aaaa ITI Type1.5_Back 703 - 983 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3LZBB 2.7 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_niiai APEdist_aaaa ITI Type1.5_Back 703 - 983 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3LZBC 2.7 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_niiai APEdist_aaaa ITI Type1.5_Back 704 - 983 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3LZBD 2.7 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_niiai APEdist_aaaa ITI Type1.5_Back 703 - 983 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3POZA 1.5 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-none TYR APEdihe_niiai APEdist_aaaa 03P Type1.5_Back 701 - 1017 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3W2SA 1.9 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa W2R Type1.5_Back 701 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3W32A 1.8 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa W32 Type1.5_Back 701 - 1017 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3W33A 1.7 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa W19 Type1.5_Back 701 - 1018 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 1XKKA 2.4 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_nnoai APEdist_aaaa FMM Type1.5_Back 702 - 1018 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8PO1A 2.11 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa 2EI Type1.5_Back 699 - 984 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8PO2A 2.28 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa 26X Type1.5_Back 705 - 984 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8PO2B 2.28 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa 26X Type1.5_Back 702 - 984 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9EWSA 2.435 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa A1H7N Type1.5_Back 703 - 984 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9EWTA 3.019 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa A1H7O Type1.5_Back 703 - 984 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9EWTB 3.019 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa A1H7O Type1.5_Back 703 - 984 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9GC4A 2.415 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa A1IZ7 Type1.5_Back 703 - 984 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9GC4B 2.415 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa A1IZ7 Type1.5_Back 703 - 984 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9HBOA 2.45 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-none TYR APEdihe_niiai APEdist_aaaa A1IUK Type1.5_Back 702 - 986 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9HBOB 2.45 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-in TYR APEdihe_iiiai APEdist_aaaa A1IUK Type1.5_Back 702 - 985 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WAKC 2.4 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_niiai APEdist_aaaa TQA Type1.5_Front 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WXNC 1.76 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa UEJ Type1.5_Front 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WXND 1.76 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa UEJ Type1.5_Front 702 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8TO3A 2.49 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa IXC Type1.5_Front 702 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7LG8B 2.93 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_niiai APEdist_aaaa VNS, 8RC Type1.5_Front, Type1 702 - 1002 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5ZWJA 2.9 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none none-none TYR APEdihe_nniai APEdist_aaaa 9LL Type3 702 - 985 0 None T790M,C797S,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8A2BA 1.69 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa KY9 Type3 702 - 990 0 None L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6P1DC 2.4 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa NQ1, ANP Type3, ATPlike 702 - 1006 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6P1DD 2.4 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa NQ1, ANP Type3, ATPlike 701 - 1008 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXQA 1.83 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa VNS, ANP Type3, ATPlike 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXQC 1.83 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa VNS, ANP Type3, ATPlike 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6XL4B 2.06 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa NQ1, Q6K Type3, Type1 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXPC 2.16 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa JBJ, YY3 Type3, Type1 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXPE 2.16 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa JBJ, YY3 Type3, Type1 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7LG8A 2.93 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa VNS, 8RC Type3, Type1 702 - 1006 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7LG8C 2.93 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa VNS, 8RC Type3, Type1 703 - 1004 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7LG8D 2.93 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa VNS, 8RC Type3, Type1 702 - 1003 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7A2AA 1.9 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa 57N, 7G9 Type3, Type1 700 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7A2AB 1.9 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa 57N, 7G9 Type3, Type1 699 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7K1HA 2.602 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa VNS, YY3 Type3, Type1 701 - 1007 0 None L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7K1HB 2.602 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa VNS, YY3 Type3, Type1 701 - 1008 0 None L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7K1HC 2.602 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa VNS, YY3 Type3, Type1 701 - 1007 0 None L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7K1HD 2.602 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa VNS, YY3 Type3, Type1 701 - 1007 0 None L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7K1HE 2.602 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa VNS, YY3 Type3, Type1 703 - 1007 0 None L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7K1HF 2.602 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa VNS, YY3 Type3, Type1 701 - 1007 0 None L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6P1DA 2.4 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa ANP ATPlike 700 - 1021 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WAKB 2.4 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa ANP ATPlike 701 - 1020 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WXNB 1.76 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa ANP ATPlike 701 - 1021 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8FV3B 2.1 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa ANP ATPlike 701 - 1021 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8FV3D 2.1 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa ANP ATPlike 701 - 1008 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8FV4A 2.2 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa ANP ATPlike 701 - 1013 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8TO3C 2.49 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa ANP ATPlike 702 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8TO3D 2.49 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa ANP ATPlike 702 - 1008 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8TO4A 2.99 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa ANP ATPlike 701 - 1021 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4ZSEA 1.97 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa ANP ATPlike 699 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4ZSEB 1.97 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa ANP ATPlike 698 - 1022 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4ZSEC 1.97 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa ANP ATPlike 700 - 1013 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXMA 2.192 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa ANP ATPlike 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8PO4B 1.621 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa ATP ATPlike 700 - 1014 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2GS7A 2.6 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa ANP ATPlike 703 - 1012 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2GS7B 2.6 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa ANP ATPlike 701 - 1016 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3GT8A 2.955 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nnnai APEdist_aaaa ANP ATPlike 700 - 1014 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3GT8B 2.955 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nnnai APEdist_aaaa ANP ATPlike 701 - 1007 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3GT8C 2.955 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa ANP ATPlike 699 - 1007 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3GT8D 2.955 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nnnai APEdist_aaaa ANP ATPlike 701 - 1010 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5CNOA 1.55 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa ANP ATPlike 700 - 1015 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5CNNB 1.9 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa ANP ATPlike 700 - 1014 0 None I706Q Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6XL4C 2.06 Inactive DFGin‑BLBtrans DFGAsp-rot-in out-out out-none TYR APEdihe_niiai APEdist_aaaa No_ligand No_ligand 700 - 1011 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7UKWD 2.6 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa No_ligand No_ligand 702 - 1012 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8FV4B 2.2 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa No_ligand No_ligand 702 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2RFDA 3.6 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa No_ligand No_ligand 703 - 1018 0 None K823E Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2RFDB 3.6 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 703 - 1018 0 None K823E Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2RFEA 2.9 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa No_ligand No_ligand 702 - 1002 0 None K823E Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2RFEB 2.9 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa No_ligand No_ligand 703 - 1012 0 None K823E Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2RFEC 2.9 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa No_ligand No_ligand 702 - 983 0 None K823E Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2RFED 2.9 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa No_ligand No_ligand 703 - 1018 0 None K823E Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V66A 1.79 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa QP1 Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V66B 1.79 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa QP1 Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V66C 1.79 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa QP1 Type1 701 - 1012 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6KB 2.2 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nnnai APEdist_aaaa QQJ Type1 700 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6KE 2.2 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa QQJ Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6KH 2.2 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa QQJ Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6OA 2.1 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa QQM Type1 701 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6OB 2.1 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa QQM Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6OF 2.1 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa QQM Type1 701 - 1012 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6OG 2.1 Inactive DFGin‑BLBtrans DFGAsp-rot-in out-out out-none TYR APEdihe_nniai APEdist_aaaa QQM Type1 701 - 1009 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V5NB 2.4 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa QP7 Type1 700 - 1008 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V5NC 2.4 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa QP7 Type1 701 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V5ND 2.4 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa QP7 Type1 701 - 1008 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V5PB 2.3 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa QP4 Type1 701 - 1012 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V5PC 2.3 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa QP4 Type1 701 - 1008 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V5PD 2.3 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa QP4 Type1 701 - 1008 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7UKWB 2.6 Inactive DFGin‑BLBtrans DFGAsp-rot-in out-out none-none TYR APEdihe_nniai APEdist_aaaa ZRT Type1 702 - 1010 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7UKWC 2.6 Inactive DFGin‑BLBtrans DFGAsp-rot-in out-out out-none TYR APEdihe_nniai APEdist_aaaa ZRT Type1 700 - 1005 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2AC 1.85 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa 7XO Type1 700 - 1015 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2CA 2.05 Inactive DFGin‑BLBtrans DFGAsp-rot-in out-out out-none TYR APEdihe_niiai APEdist_aaaa 7XR Type1 700 - 1015 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2CB 2.05 Inactive DFGin‑BLBtrans DFGAsp-rot-in out-out out-none TYR APEdihe_niiai APEdist_aaaa 7XR Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2FA 2.2 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa 7XU Type1 700 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2FB 2.2 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 7XU Type1 699 - 1010 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2FC 2.2 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa 7XU Type1 700 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2FD 2.2 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa 7XU Type1 697 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXIA 3.0 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa 8BS Type1 700 - 1006 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXID 3.0 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa 8BS Type1 702 - 1006 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXLA 2.4 Inactive DFGin‑BLBtrans DFGAsp-rot-in out-out out-none TYR APEdihe_nniai APEdist_aaaa VO7 Type1 701 - 1013 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7KY0B 3.1 Inactive DFGin‑BLBtrans DFGAsp-rot-in out-out out-none TYR APEdihe_nniai APEdist_aaaa XA4 Type1 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7KY0D 3.1 Inactive DFGin‑BLBtrans DFGAsp-rot-in out-out out-none TYR APEdihe_nniai APEdist_aaaa XA4 Type1 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7U98B 3.42 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa M1O Type1 701 - 1005 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7U98C 3.42 Inactive DFGin‑BLBtrans DFGAsp-rot-in out-out out-none TYR APEdihe_nniai APEdist_aaaa M1O Type1 702 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7U98D 3.42 Inactive DFGin‑BLBtrans DFGAsp-rot-in out-out none-none TYR APEdihe_nniai APEdist_aaaa M1O Type1 701 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8F1WA 3.2 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa R2E Type1 701 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8F1WB 3.2 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa R2E Type1 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8F1WC 3.2 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa R2E Type1 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8F1WD 3.2 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa R2E Type1 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6Z4DA 2.0 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa 8BS Type1 701 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7A6JA 2.0 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa R2E Type1 699 - 982 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7A6KA 2.0 Inactive DFGin‑BLBtrans DFGAsp-rot-in out-out out-none TYR APEdihe_niiai APEdist_aaaa R28 Type1 700 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7A6KB 2.0 Inactive DFGin‑BLBtrans DFGAsp-rot-none out-none none-none TYR APEdihe_niiai APEdist_aaaa R28 Type1 700 - 982 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7A6KC 2.0 Inactive DFGin‑BLBtrans DFGAsp-rot-none out-none none-none TYR APEdihe_niiai APEdist_aaaa R28 Type1 700 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7A6KD 2.0 Inactive DFGin‑BLBtrans DFGAsp-rot-none out-out none-none TYR APEdihe_nniai APEdist_aaaa R28 Type1 702 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4I24A 1.8 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa 1C9 Type1 700 - 1014 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4I24B 1.8 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 1C9 Type1 700 - 1014 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5YU9A 1.95 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa 1E8 Type1 700 - 1017 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5YU9B 1.95 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa 1E8 Type1 699 - 1011 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5YU9C 1.95 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa 1E8 Type1 697 - 1021 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5YU9D 1.95 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa 1E8 Type1 700 - 1012 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4I22A 1.71 Inactive DFGin‑BLBtrans DFGAsp-rot-in out-out out-none TYR APEdihe_nniai APEdist_aaaa IRE Type1 700 - 1014 0 None T790M,L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9GC6A 1.901 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa A1IZ9 Type1 698 - 1014 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9GC6B 1.901 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nnnai APEdist_aaaa A1IZ9 Type1 698 - 1014 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9GDVA 2.218 Inactive DFGin‑BLBtrans DFGAsp-rot-in out-none out-none TYR APEdihe_nniai APEdist_aaaa Q6K Type1 702 - 985 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9GDVB 2.218 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-none none-none TYR APEdihe_nniai APEdist_aaaa Q6K Type1 702 - 985 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4HJOA 2.75 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-in TYR APEdihe_iiiai APEdist_aaaa AQ4 Type1 703 - 984 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6JXTA 2.307 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-in TYR APEdihe_iiiai APEdist_aaaa YY3 Type1 697 - 984 0 None E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2AB 1.85 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 7XO, ANP Type1, ATPlike 700 - 1022 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2AA 1.85 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa 7XO, ANP Type1, Allosteric 700 - 1011 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9GC5A 1.909 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa A1IZ8 Type1.5_Back 699 - 1012 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9GC5B 1.909 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa A1IZ8 Type1.5_Back 699 - 1012 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8PO3A 2.13 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa 2II Type1.5_Front 706 - 1001 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4RIWB 3.1 Inactive DFGin‑None DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa ADP ATPlike 688 - 984 0 None V948R,F997A,L1001A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4RIWD 3.1 Inactive DFGin‑None DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa ADP ATPlike 688 - 984 0 None V948R,F997A,L1001A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4RIXB 3.1 Inactive DFGin‑None DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa ADP ATPlike 688 - 984 0 None V948R,F997A,L1001A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4RIXD 3.1 Inactive DFGin‑None DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa ADP ATPlike 688 - 984 0 None V948R,F997A,L1001A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4RIYB 2.981 Inactive DFGin‑None DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa ADP ATPlike 688 - 984 0 None V948R,F997A,L1001A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4RIYD 2.981 Inactive DFGin‑None DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa ADP ATPlike 688 - 984 0 None V948R,F997A,L1001A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8EMEA 3.32 Inactive DFGin‑None DFGAsp-rot-out out-out none-none TYR APEdihe_nnnan APEdist_aaaa No_ligand No_ligand 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3GOPA 2.8 Inactive DFGin‑None DFGAsp-rot-out in-na none-none TYR APEdihe_nniai APEdist_aaaa No_ligand No_ligand 676 - 1018 0 None K745M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXIB 3.0 Inactive DFGin‑None DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa 8BS Type1 702 - 1004 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7KY0C 3.1 Inactive DFGin‑None DFGAsp-rot-in out-out out-none TYR APEdihe_nniai APEdist_aaaa XA4 Type1 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7U98A 3.42 Inactive DFGin‑None DFGAsp-rot-out out-out out-none TYR APEdihe_nnnai APEdist_aaaa M1O Type1 701 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7ZYQB 2.1 Inactive DFGin‑None DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa V58 Type1 700 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2JIVA 3.5 Inactive DFGin‑None DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa HKI Type1.5_Back 700 - 984 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8H7XB 3.404 Inactive DFGinter‑None DFGAsp-rot-out in-in out-none TYR APEdihe_nniai APEdist_aaaa No_ligand No_ligand 697 - 1018 0 None T790M,C797S Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5XGNB 3.0 Inactive DFGinter‑None DFGAsp-rot-out in-in out-out TYR APEdihe_oiiai APEdist_aaaa No_ligand No_ligand 697 - 1019 0 None T790M,C797S Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2JITB 3.1 Inactive DFGinter‑None DFGAsp-rot-out in-in out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 697 - 1018 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2JIUB 3.05 Inactive DFGinter‑None DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 695 - 1004 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4G5PB 3.17 Inactive DFGinter‑None DFGAsp-rot-out in-in out-none TYR APEdihe_niiai APEdist_aaaa No_ligand No_ligand 697 - 1018 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3IKAB 2.9 Inactive DFGinter‑None DFGAsp-rot-out in-in out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 697 - 1017 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4WD5B 3.3 Inactive DFGinter‑None DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 697 - 1016 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9U91A 3.2 Inactive DFGinter‑None DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa A1EOG Type1 703 - 983 0 None T790M,C797S,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5UWDA 3.06 Inactive DFGinter‑None DFGAsp-rot-in out-out out-none TYR APEdihe_niiai APEdist_aaaa 8OV Type1 702 - 984 0 None T790M,L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2RF9A 3.5 Inactive DFGout‑BBAminus DFGAsp-rot-in out-none in-out TYR APEdihe_ooiai APEdist_aaaa No_ligand No_ligand 699 - 983 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4ZJVA 2.7 Inactive DFGout‑BBAminus DFGAsp-rot-in out-out in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 703 - 985 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4ZJVB 2.7 Inactive DFGout‑BBAminus DFGAsp-rot-in out-out in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 703 - 982 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5HG5A 1.52 Inactive DFGout‑BBAminus DFGAsp-rot-in out-out in-in TYR APEdihe_iiiai APEdist_aaaa 633 Type1 700 - 1001 0 None T790M,L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5HG7A 1.85 Inactive DFGout‑BBAminus DFGAsp-rot-in out-out in-in TYR APEdihe_iiiai APEdist_aaaa 630 Type1 702 - 984 0 None T790M,L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5HG8A 1.42 Inactive DFGout‑BBAminus DFGAsp-rot-in out-out in-in TYR APEdihe_iiiai APEdist_aaaa 634 Type1 700 - 999 0 None T790M,L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5HG9A 2.15 Inactive DFGout‑BBAminus DFGAsp-rot-in out-out in-in TYR APEdihe_iiiai APEdist_aaaa 63A Type1 702 - 985 0 None T790M,L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5U8LA 1.6 Inactive DFGout‑BBAminus DFGAsp-rot-in out-out in-in TYR APEdihe_iiiai APEdist_aaaa O44 Type1 702 - 990 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5UG8A 1.46 Inactive DFGout‑BBAminus DFGAsp-rot-in out-out in-in TYR APEdihe_iiiai APEdist_aaaa 8BP Type1 702 - 985 0 None T790M,L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5UG9A 1.33 Inactive DFGout‑BBAminus DFGAsp-rot-in out-out in-in TYR APEdihe_iiiai APEdist_aaaa 8AM Type1 702 - 985 0 None T790M,L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5UGAA 1.82 Inactive DFGout‑BBAminus DFGAsp-rot-in out-out in-in TYR APEdihe_iiiai APEdist_aaaa 8BM Type1 703 - 985 0 None T790M,L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5UGCA 1.58 Inactive DFGout‑BBAminus DFGAsp-rot-in out-out in-in TYR APEdihe_iiiai APEdist_aaaa 8BS Type1 702 - 985 0 None T790M,L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4I1ZA 3.0 Inactive DFGout‑None DFGAsp-rot-in out-out in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 701 - 987 0 None T790M,L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4I21A 3.37 Inactive DFGout‑None DFGAsp-rot-in out-out in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 703 - 1019 0 None T790M,L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4I21B 3.37 Inactive DFGout‑None DFGAsp-rot-in out-out in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 703 - 1020 0 None T790M,L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2RF9B 3.5 Inactive DFGout‑None DFGAsp-rot-in out-none in-out TYR APEdihe_ioiai APEdist_aaaa No_ligand No_ligand 701 - 985 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4I20A 3.34 Inactive DFGout‑None DFGAsp-rot-in out-out in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 701 - 987 0 None L858R,V948R Epidermal growth factor receptor
TYR EPHA1 EPHA1_HUMAN AF-P21709-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 616 - 890 0 None None Ephrin type-A receptor 1
TYR EPHA1 EPHA1_HUMAN AF-P21709-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 616 - 890 0 None None Ephrin type-A receptor 1
TYR EPHA2 EPHA2_HUMAN 4TRLA 2.452 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 599 - 875 0 PTR772 None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 7KJBA 2.8 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 591 - 965 0 None S897E,S901E Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5NK0A 1.597 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa 91E Type1 602 - 894 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5NK8A 1.761 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa 90Z Type1 605 - 894 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 6FNHA 1.379 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa DXK Type1 602 - 889 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 6FNHB 1.379 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in out-none TYR APEdihe_niiai APEdist_aaaa DXK Type1 602 - 882 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5NK3A 1.586 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 92Q Type1.5_Back 601 - 888 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 8QQYA 1.8 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in out-none TYR APEdihe_niiai APEdist_aaaa WT3 Type1.5_Back 605 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5I9VA 1.458 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa AGS ATPlike 605 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 1MQBA 2.3 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out none-none TYR APEdihe_niiai APEdist_aaaa ANP ATPlike 605 - 887 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 1MQBB 2.3 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa ANP ATPlike 602 - 883 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 7KJAB 1.75 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa ACP ATPlike 590 - 965 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN AF-P29317-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 605 - 881 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN AF-P29317-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 605 - 881 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 4P2KA 1.499 Inactive DFGin‑BLAminus DFGAsp-rot-out in-out in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 600 - 876 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5I9UA 1.889 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_nniai APEdist_aaaa No_ligand No_ligand 601 - 894 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5EK7A 1.901 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 586 - 875 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5EK7B 1.901 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 586 - 875 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5IA0A 1.948 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa A5B Type1 604 - 889 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5NKAA 1.377 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_niiai APEdist_aaaa 91H Type1 605 - 895 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 6FNHC 1.379 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa DXK Type1 600 - 890 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 8BINA 1.5 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in out-in TYR APEdihe_iiiai APEdist_aaaa QRR Type1 605 - 887 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 8BIOA 1.6 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in out-in TYR APEdihe_iiiai APEdist_aaaa QRD Type1.5_Back 605 - 894 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5I9WA 1.359 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa ANP ATPlike 605 - 895 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 7KJCA 2.3 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in out-none TYR APEdihe_niiai APEdist_aaaa ACP ATPlike 590 - 976 0 None S901E Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 7KJCB 2.3 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa ACP ATPlike 590 - 965 0 None S901E Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 7KJAA 1.75 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa ACP ATPlike 590 - 976 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5I9XA 1.427 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa DB8 Type1 604 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5I9YA 1.228 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in out-none TYR APEdihe_nnnai APEdist_aaaa 1N1 Type1 600 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5I9ZA 1.698 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in out-none TYR APEdihe_nniai APEdist_aaaa 627 Type1 604 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5IA0B 1.948 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in out-none TYR APEdihe_nniai APEdist_aaaa A5B Type1 600 - 882 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5IA0C 1.948 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa A5B Type1 600 - 890 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5IA3A 1.788 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in out-none TYR APEdihe_nniai APEdist_aaaa P17 Type1 602 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5NJZA 1.768 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa 8ZH Type1 604 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5NK1A 1.548 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 90N Type1 604 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5NK2A 1.649 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 8ZZ Type1 598 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5NK4A 1.45 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 90E Type1 601 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5NK5A 1.329 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 90K Type1 605 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5NK6A 1.267 Inactive DFGin‑BLBminus DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa 90W Type1 605 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5NK7A 1.889 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 8ZZ Type1 604 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5NK9A 1.588 Inactive DFGin‑BLBminus DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa 912 Type1 605 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5NKBA 1.5 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 8ZT Type1 605 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5NKCA 1.448 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in out-none TYR APEdihe_niiai APEdist_aaaa 90T Type1 601 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5NKDA 1.408 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 91K Type1 600 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5NKEA 1.39 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 90B Type1 605 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5NKFA 1.099 Inactive DFGin‑BLBminus DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa 8ZN Type1 605 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5NKGA 1.1 Inactive DFGin‑BLBminus DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa 8ZK Type1 605 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5NKHA 1.29 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 8ZQ Type1 601 - 895 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5NKIA 1.675 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa 8ZW Type1 604 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 8BK0A 1.7 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in out-none TYR APEdihe_nniai APEdist_aaaa QJI Type1 605 - 887 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5IA2A 1.619 Inactive DFGin‑BLBminus DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa L66 Type1.5_Back 598 - 888 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 4PDOA 2.104 Inactive DFGin‑None DFGAsp-rot-in in-out none-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 590 - 875 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 4PDOB 2.104 Inactive DFGin‑None DFGAsp-rot-in in-out none-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 590 - 875 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5IA1A 2.036 Inactive DFGin‑None DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa ZZL Type1 605 - 888 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 8XPVA 1.55 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa 4Z5 Type2 604 - 895 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 6FNFA 1.556 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa DXH Type2 606 - 894 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 6FNGA 1.038 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-none TYR APEdihe_niiai APEdist_aaaa DWT Type2 599 - 897 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 6HESA 1.128 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa G0H Type2 599 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 6HETA 1.208 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa G0Q Type2 605 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 6HEUA 1.719 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa G0N Type2 600 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 6HEVA 1.28 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa G0K Type2 600 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 6HEWA 1.268 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-in TYR APEdihe_iiiai APEdist_aaaa G0E Type2 605 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 6HEXA 1.413 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa G02 Type2 605 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 6HEYA 1.367 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-none TYR APEdihe_niiai APEdist_aaaa FZW Type2 600 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 6Q7BA 1.009 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-in TYR APEdihe_iiiai APEdist_aaaa HO5 Type2 599 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 6Q7CA 1.049 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-in TYR APEdihe_iiiai APEdist_aaaa HOK Type2 599 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 6Q7DA 0.978 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa HOT Type2 600 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 6Q7EA 1.059 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa HMW Type2 601 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 6Q7GA 1.047 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa HO8 Type2 601 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 8BM8A 1.68 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa QT1 Type2 605 - 895 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 8BOCA 1.9 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa QUF Type2 605 - 888 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 8BODA 1.5 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa QTX Type2 605 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 8BOGA 1.47 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa QUU Type2 600 - 895 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 8BOHA 1.42 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa R0T Type2 604 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 8BOIA 1.63 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa R0O Type2 604 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 8BOKA 2.02 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa R0X Type2 605 - 890 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 8BOMA 1.12 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa QU6 Type2 605 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5IA4A 1.797 Inactive DFGout‑None DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa 88Z Type2 605 - 877 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5IA5A 1.776 Inactive DFGout‑None DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa GV0 Type2 605 - 880 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 6Q7FA 1.204 Inactive DFGout‑None DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa HNZ Type2 605 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 8BOFA 1.82 Inactive DFGout‑None DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa R3L Type2 605 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA3 EPHA3_HUMAN 2QOCA 1.25 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-none TYR APEdihe_niiai APEdist_aaaa ANP ATPlike 613 - 906 0 None None Ephrin type-A receptor 3
TYR EPHA3 EPHA3_HUMAN 3FXXA 1.7 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-in TYR APEdihe_iiiai APEdist_aaaa ANP ATPlike 606 - 904 0 None A608T Ephrin type-A receptor 3
TYR EPHA3 EPHA3_HUMAN 2QO7A 1.605 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out none-none TYR APEdihe_nnnai APEdist_aaaa ANP ATPlike 595 - 904 0 PTR701 None Ephrin type-A receptor 3
TYR EPHA3 EPHA3_HUMAN 2QO9A 1.55 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-out TYR APEdihe_noiai APEdist_aaaa ANP ATPlike 608 - 904 0 None None Ephrin type-A receptor 3
TYR EPHA3 EPHA3_HUMAN 2QOQA 1.6 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_niiai APEdist_aaaa ANP ATPlike 595 - 906 0 PTR701 None Ephrin type-A receptor 3
TYR EPHA3 EPHA3_HUMAN AF-P29320-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 613 - 888 0 None None Ephrin type-A receptor 3
TYR EPHA3 EPHA3_HUMAN AF-P29320-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 613 - 888 0 None None Ephrin type-A receptor 3
TYR EPHA3 EPHA3_HUMAN 2QOBA 1.65 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-none TYR APEdihe_niiai APEdist_aaaa No_ligand No_ligand 609 - 906 0 PTR701 None Ephrin type-A receptor 3
TYR EPHA3 EPHA3_HUMAN 3FY2A 1.8 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 607 - 904 0 None A608T Ephrin type-A receptor 3
TYR EPHA3 EPHA3_HUMAN 2GSFA 1.77 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa No_ligand No_ligand 595 - 904 0 None A608T Ephrin type-A receptor 3
TYR EPHA3 EPHA3_HUMAN 2QO2A 1.6 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in none-out TYR APEdihe_nnnao APEdist_aaaa No_ligand No_ligand 595 - 904 0 None None Ephrin type-A receptor 3
TYR EPHA3 EPHA3_HUMAN 2QOKA 1.2 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa No_ligand No_ligand 595 - 904 0 None Y596F,Y602F,S768A Ephrin type-A receptor 3
TYR EPHA3 EPHA3_HUMAN 2QONA 1.79 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-none TYR APEdihe_nniai APEdist_aaaa No_ligand No_ligand 595 - 905 0 PTR701 Y596F,Y602F,Y742A Ephrin type-A receptor 3
TYR EPHA3 EPHA3_HUMAN 4GK3A 1.898 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa L87 Type1 609 - 903 0 None None Ephrin type-A receptor 3
TYR EPHA3 EPHA3_HUMAN 4P5QA 1.35 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa Q0B Type1 609 - 904 0 None None Ephrin type-A receptor 3
TYR EPHA3 EPHA3_HUMAN 4TWOA 2.047 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa 37W Type1 609 - 906 0 None None Ephrin type-A receptor 3
TYR EPHA3 EPHA3_HUMAN 4G2FA 1.699 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa C07 Type1.5_Back 609 - 903 0 None None Ephrin type-A receptor 3
TYR EPHA3 EPHA3_HUMAN 4GK2A 2.195 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa L66 Type1.5_Back 609 - 903 0 None None Ephrin type-A receptor 3
TYR EPHA3 EPHA3_HUMAN 4GK4A 2.1 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa L90 Type1.5_Back 609 - 903 0 None None Ephrin type-A receptor 3
TYR EPHA3 EPHA3_HUMAN 6IN0A 1.501 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-none TYR APEdihe_nniai APEdist_aaaa O4B, O4B Type3, Allosteric 613 - 903 0 None None Ephrin type-A receptor 3
TYR EPHA3 EPHA3_HUMAN 2QOOA 1.25 Inactive DFGin‑None DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa No_ligand No_ligand 595 - 904 0 None Y596F,Y602F,Y742F Ephrin type-A receptor 3
TYR EPHA3 EPHA3_HUMAN 2QOFA 1.2 Inactive DFGin‑None DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa No_ligand No_ligand 595 - 906 0 None Y596F Ephrin type-A receptor 3
TYR EPHA3 EPHA3_HUMAN 2QODA 1.15 Inactive DFGin‑None DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa No_ligand No_ligand 595 - 904 0 None Y602F Ephrin type-A receptor 3
TYR EPHA3 EPHA3_HUMAN 2QOIA 1.25 Inactive DFGin‑None DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa No_ligand No_ligand 595 - 904 0 None Y596F,Y602F Ephrin type-A receptor 3
TYR EPHA3 EPHA3_HUMAN 2QOLA 1.07 Inactive DFGin‑None DFGAsp-rot-in in-in none-none TYR APEdihe_nnnan APEdist_aaaa No_ligand No_ligand 595 - 904 0 None Y596F,Y602F,S768G Ephrin type-A receptor 3
TYR EPHA3 EPHA3_HUMAN 4P4CA 1.599 Inactive DFGin‑None DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa 25Q Type1 613 - 904 0 None None Ephrin type-A receptor 3
TYR EPHA3 EPHA3_HUMAN 3DZQA 1.75 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa IFC Type2 609 - 904 0 None None Ephrin type-A receptor 3
TYR EPHA3 EPHA3_HUMAN 4P5ZA 2.002 Inactive DFGout‑None DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa Q7M Type2 609 - 903 0 None None Ephrin type-A receptor 3
TYR EPHA3 EPHA3_HUMAN 4TWNA 1.706 Inactive DFGout‑None DFGAsp-rot-in in-in out-none TYR APEdihe_niiai APEdist_aaaa B96 Type2 609 - 904 0 None None Ephrin type-A receptor 3
TYR EPHA4 EPHA4_HUMAN AF-P54764-K1A -1.0 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 613 - 888 0 None None Ephrin type-A receptor 4
TYR EPHA4 EPHA4_HUMAN AF-P54764-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 613 - 888 0 None None Ephrin type-A receptor 4
TYR EPHA5 EPHA5_HUMAN AF-P54756-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 667 - 942 0 None None Ephrin type-A receptor 5
TYR EPHA5 EPHA5_HUMAN AF-P54756-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 667 - 942 0 None None Ephrin type-A receptor 5
TYR EPHA5 EPHA5_HUMAN 2R2PA 2.4 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa No_ligand No_ligand 662 - 939 0 None None Ephrin type-A receptor 5
TYR EPHA6 EPHA6_HUMAN AF-Q9UF33-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 623 - 940 0 None None Ephrin type-A receptor 6
TYR EPHA6 EPHA6_HUMAN AF-Q9UF33-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 623 - 940 0 None None Ephrin type-A receptor 6
TYR EPHA7 EPHA7_HUMAN 7EEDA 3.05 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa No_ligand No_ligand 607 - 899 0 None D751H Ephrin type-A receptor 7
TYR EPHA7 EPHA7_HUMAN 2REIA 1.6 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa No_ligand No_ligand 607 - 899 0 None None Ephrin type-A receptor 7
TYR EPHA7 EPHA7_HUMAN 7EECA 3.1 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa No_ligand No_ligand 607 - 899 0 None G656R Ephrin type-A receptor 7
TYR EPHA7 EPHA7_HUMAN AF-Q15375-K1A -1.0 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 625 - 900 0 None None Ephrin type-A receptor 7
TYR EPHA7 EPHA7_HUMAN AF-Q15375-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 625 - 900 0 None None Ephrin type-A receptor 7
TYR EPHA7 EPHA7_HUMAN 7EEFA 2.6 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in none-out TYR APEdihe_oiiai APEdist_aaaa No_ligand No_ligand 606 - 899 0 None G656E Ephrin type-A receptor 7
TYR EPHA7 EPHA7_HUMAN 3DKOA 2.0 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa IHZ Type2 607 - 899 0 None None Ephrin type-A receptor 7
TYR EPHA8 EPHA8_HUMAN AF-P29322-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 627 - 902 0 None None Ephrin type-A receptor 8
TYR EPHA8 EPHA8_HUMAN AF-P29322-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 627 - 902 0 None None Ephrin type-A receptor 8
TYR EPHA8 EPHA8_HUMAN 3KULA 2.15 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa No_ligand No_ligand 627 - 900 0 None None Ephrin type-A receptor 8
TYR EPHA8 EPHA8_HUMAN 3KULB 2.15 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 627 - 899 0 PTR793 None Ephrin type-A receptor 8
TYR EPHB1 EPHB1_HUMAN AF-P54762-K1A -1.0 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 611 - 888 0 None None Ephrin type-B receptor 1
TYR EPHB1 EPHB1_HUMAN AF-P54762-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 611 - 888 0 None None Ephrin type-B receptor 1
TYR EPHB1 EPHB1_HUMAN 3ZFXA 2.5 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 611 - 893 0 None None Ephrin type-B receptor 1
TYR EPHB1 EPHB1_HUMAN 3ZFXB 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnan APEdist_aaaa No_ligand No_ligand 611 - 892 0 None None Ephrin type-B receptor 1
TYR EPHB1 EPHB1_HUMAN 3ZFXC 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-none in-none TYR APEdihe_nnnai APEdist_aaaa No_ligand No_ligand 614 - 892 0 None None Ephrin type-B receptor 1
TYR EPHB1 EPHB1_HUMAN 3ZFXD 2.5 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 611 - 893 0 None None Ephrin type-B receptor 1
TYR EPHB1 EPHB1_HUMAN 3ZFXE 2.5 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 611 - 893 0 None None Ephrin type-B receptor 1
TYR EPHB1 EPHB1_HUMAN 3ZFXF 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-none in-none TYR APEdihe_nnnan APEdist_aaaa No_ligand No_ligand 612 - 893 0 None None Ephrin type-B receptor 1
TYR EPHB1 EPHB1_HUMAN 3ZFXG 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnan APEdist_aaaa No_ligand No_ligand 611 - 892 0 None None Ephrin type-B receptor 1
TYR EPHB1 EPHB1_HUMAN 3ZFXH 2.5 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 611 - 892 0 None None Ephrin type-B receptor 1
TYR EPHB1 EPHB1_HUMAN 3ZFXI 2.5 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_iioai APEdist_aaaa No_ligand No_ligand 611 - 891 0 None None Ephrin type-B receptor 1
TYR EPHB1 EPHB1_HUMAN 5MJAB 2.14 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 7O3 Type1 609 - 890 0 PTR647,PTR778 None Ephrin type-B receptor 1
TYR EPHB1 EPHB1_HUMAN 5MJBB 2.23 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 7O3 Type1 608 - 890 0 PTR647,PTR778 None Ephrin type-B receptor 1
TYR EPHB1 EPHB1_HUMAN 5MJAA 2.14 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa 7O3 Type1.5_Back 609 - 892 0 PTR647,PTR778 None Ephrin type-B receptor 1
TYR EPHB1 EPHB1_HUMAN 5MJBA 2.23 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 7O3 Type1.5_Back 608 - 891 0 PTR647,PTR778 None Ephrin type-B receptor 1
TYR EPHB1 EPHB1_HUMAN 7KPMA 1.608 Inactive DFGin‑None DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa ADP ATPlike 611 - 888 0 PTR647 None Ephrin type-B receptor 1
TYR EPHB1 EPHB1_HUMAN 7KPLA 2.705 Inactive DFGin‑None DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa No_ligand No_ligand 611 - 888 0 PTR647 None Ephrin type-B receptor 1
TYR EPHB1 EPHB1_HUMAN 6UMWA 1.982 Inactive DFGin‑None DFGAsp-rot-in in-out none-none TYR APEdihe_nniai APEdist_aaaa CTC Type1.5_Back 611 - 889 0 PTR647 None Ephrin type-B receptor 1
TYR EPHB2 EPHB2_HUMAN AF-P29323-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 613 - 890 0 None None Ephrin type-B receptor 2
TYR EPHB2 EPHB2_HUMAN AF-P29323-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 613 - 890 0 None None Ephrin type-B receptor 2
TYR EPHB2 EPHB2_HUMAN 3ZFMA 2.27 Inactive DFGin‑None DFGAsp-rot-in in-none none-none TYR APEdihe_nnnai APEdist_aaaa No_ligand No_ligand 615 - 894 0 None None Ephrin type-B receptor 2
TYR EPHB3 EPHB3_HUMAN AF-P54753-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 625 - 902 0 None None Ephrin type-B receptor 3
TYR EPHB3 EPHB3_HUMAN AF-P54753-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 625 - 902 0 None None Ephrin type-B receptor 3
TYR EPHB3 EPHB3_HUMAN 3ZFYA 2.2 Inactive DFGin‑None DFGAsp-rot-in in-out none-none TYR APEdihe_niiai APEdist_aaaa No_ligand No_ligand 632 - 905 0 None None Ephrin type-B receptor 3
TYR EPHB3 EPHB3_HUMAN 3ZFYB 2.2 Inactive DFGin‑None DFGAsp-rot-in in-none none-none TYR APEdihe_niiai APEdist_aaaa No_ligand No_ligand 631 - 905 0 None None Ephrin type-B receptor 3
TYR EPHB3 EPHB3_HUMAN 5L6OA 1.88 Inactive DFGin‑None DFGAsp-rot-in in-in none-in TYR APEdihe_iiiai APEdist_aaaa 6P6 Type1 632 - 905 0 None A899P Ephrin type-B receptor 3
TYR EPHB3 EPHB3_HUMAN 5L6PA 2.26 Inactive DFGin‑None DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa 6P8 Type1 632 - 905 0 None A899P Ephrin type-B receptor 3
TYR EPHB4 EPHB4_HUMAN 6FNLA 1.269 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_niiai APEdist_aaaa No_ligand No_ligand 607 - 888 0 None Y774E,A803V,V870I Ephrin type-B receptor 4
TYR EPHB4 EPHB4_HUMAN AF-P54760-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 607 - 884 0 None None Ephrin type-B receptor 4
TYR EPHB4 EPHB4_HUMAN AF-P54760-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 607 - 884 0 None None Ephrin type-B receptor 4
TYR EPHB4 EPHB4_HUMAN 3ZEWA 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa STU Type1 609 - 888 0 PTR774 None Ephrin type-B receptor 4
TYR EPHB4 EPHB4_HUMAN 3ZEWB 2.5 None DFGin‑BLAminus DFGAsp-rot-in in-none none-none TYR APEdihe_nniai APEdist_aaaa STU Type1 609 - 887 0 PTR774 None Ephrin type-B receptor 4
TYR EPHB4 EPHB4_HUMAN 6FNKA 1.049 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa DXK Type1 604 - 889 0 None Y774E,A803V,V870I Ephrin type-B receptor 4
TYR EPHB4 EPHB4_HUMAN 6FNMA 1.157 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 1N1 Type1 608 - 889 0 None Y774E,A803V,V870I Ephrin type-B receptor 4
TYR EPHB4 EPHB4_HUMAN 4AW5A 2.33 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa 30K Type1 607 - 888 0 None None Ephrin type-B receptor 4
TYR EPHB4 EPHB4_HUMAN 2VWXA 1.65 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 7X4 Type1 608 - 888 0 None Y774E Ephrin type-B receptor 4
TYR EPHB4 EPHB4_HUMAN 2VWYA 1.65 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 7X5 Type1 608 - 888 0 None Y774E Ephrin type-B receptor 4
TYR EPHB4 EPHB4_HUMAN 2VWZA 1.65 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 7X6 Type1 608 - 888 0 None Y774E Ephrin type-B receptor 4
TYR EPHB4 EPHB4_HUMAN 2VX0A 2.1 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 7X7 Type1 608 - 888 0 None Y774E Ephrin type-B receptor 4
TYR EPHB4 EPHB4_HUMAN 2VX1A 1.65 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 7X8 Type1 608 - 888 0 None Y774E Ephrin type-B receptor 4
TYR EPHB4 EPHB4_HUMAN 2X9FA 1.75 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa X9F Type1 608 - 888 0 None Y774E Ephrin type-B receptor 4
TYR EPHB4 EPHB4_HUMAN 4BB4A 1.65 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 32W Type1 606 - 888 0 None Y774E Ephrin type-B receptor 4
TYR EPHB4 EPHB4_HUMAN 2XVDA 1.7 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa AS6 Type1.5_Back 607 - 888 0 None Y774E Ephrin type-B receptor 4
TYR EPHB4 EPHB4_HUMAN 2YN8A 2.11 Inactive DFGin‑None DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa STU Type1 608 - 888 0 None Y774E,A803V,V870I Ephrin type-B receptor 4
TYR EPHB4 EPHB4_HUMAN 2YN8B 2.11 Inactive DFGin‑None DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa STU Type1 606 - 888 0 None Y774E,A803V,V870I Ephrin type-B receptor 4
TYR EPHB4 EPHB4_HUMAN 2VWUA 2.0 Inactive DFGin‑None DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa 7X1 Type1 609 - 887 0 None Y774E Ephrin type-B receptor 4
TYR EPHB4 EPHB4_HUMAN 2VWVA 1.9 Inactive DFGin‑None DFGAsp-rot-in in-in none-none TYR APEdihe_niiai APEdist_aaaa 7X3 Type1 606 - 885 0 None Y774E Ephrin type-B receptor 4
TYR EPHB4 EPHB4_HUMAN 2VWWA 1.9 Inactive DFGin‑None DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa 7X2 Type1 609 - 887 0 None Y774E Ephrin type-B receptor 4
TYR EPHB4 EPHB4_HUMAN 6FNIA 1.468 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-none TYR APEdihe_nniai APEdist_aaaa DXH Type2 607 - 889 0 None Y774E,A803V,V870I Ephrin type-B receptor 4
TYR EPHB4 EPHB4_HUMAN 6FNJA 1.239 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-out TYR APEdihe_nnoai APEdist_aaaa DWT Type2 607 - 888 0 None Y774E,A803V,V870I Ephrin type-B receptor 4
TYR EPHB4 EPHB4_HUMAN 6FNJB 1.239 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-out TYR APEdihe_nnoai APEdist_aaaa DWT Type2 607 - 888 0 None Y774E,A803V,V870I Ephrin type-B receptor 4
TYR ERBB2 ERBB2_HUMAN AF-P04626-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 712 - 986 0 None None Receptor tyrosine-protein kinase erbB-2
TYR ERBB2 ERBB2_HUMAN AF-P04626-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 712 - 986 0 None None Receptor tyrosine-protein kinase erbB-2
TYR ERBB2 ERBB2_HUMAN 3RCDB 3.21 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out none-none TYR APEdihe_nniai APEdist_aaaa No_ligand No_ligand 713 - 1010 0 None None Receptor tyrosine-protein kinase erbB-2
TYR ERBB2 ERBB2_HUMAN 3RCDD 3.21 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out none-none TYR APEdihe_nniai APEdist_aaaa No_ligand No_ligand 713 - 1010 0 None None Receptor tyrosine-protein kinase erbB-2
TYR ERBB2 ERBB2_HUMAN 7PCDA 1.77 Inactive DFGin‑BLBminus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa 70I Type1.5_Back 710 - 991 0 None None Receptor tyrosine-protein kinase erbB-2
TYR ERBB2 ERBB2_HUMAN 7JXHA 3.27 Inactive DFGin‑BLBminus DFGAsp-rot-in out-out out-none TYR APEdihe_nniai APEdist_aaaa VOY Type1.5_Back 706 - 992 0 None None Receptor tyrosine-protein kinase erbB-2
TYR ERBB2 ERBB2_HUMAN 7JXHE 3.27 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-none TYR APEdihe_nnnai APEdist_aaaa VOY Type1.5_Back 709 - 992 0 None None Receptor tyrosine-protein kinase erbB-2
TYR ERBB2 ERBB2_HUMAN 7JXHB 3.27 Inactive DFGin‑None DFGAsp-rot-in out-out none-out TYR APEdihe_oiiai APEdist_aaaa VOY Type1.5_Back 707 - 996 0 None None Receptor tyrosine-protein kinase erbB-2
TYR ERBB2 ERBB2_HUMAN 7JXHC 3.27 Inactive DFGin‑None DFGAsp-rot-in out-out in-out TYR APEdihe_oiiai APEdist_aaaa VOY Type1.5_Back 707 - 992 0 None None Receptor tyrosine-protein kinase erbB-2
TYR ERBB2 ERBB2_HUMAN 7JXHD 3.27 Inactive DFGin‑None DFGAsp-rot-in out-out in-none TYR APEdihe_niiai APEdist_aaaa VOY Type1.5_Back 707 - 992 0 None None Receptor tyrosine-protein kinase erbB-2
TYR ERBB2 ERBB2_HUMAN 7JXHF 3.27 Inactive DFGin‑None DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa VOY Type1.5_Back 713 - 991 0 None None Receptor tyrosine-protein kinase erbB-2
TYR ERBB2 ERBB2_HUMAN 7JXHG 3.27 Inactive DFGin‑None DFGAsp-rot-in out-out in-none TYR APEdihe_nniai APEdist_aaaa VOY Type1.5_Back 706 - 992 0 None None Receptor tyrosine-protein kinase erbB-2
TYR ERBB2 ERBB2_HUMAN 7JXHH 3.27 Inactive DFGin‑None DFGAsp-rot-in out-out in-out TYR APEdihe_oiiai APEdist_aaaa VOY Type1.5_Back 707 - 992 0 None None Receptor tyrosine-protein kinase erbB-2
TYR ERBB2 ERBB2_HUMAN 3PP0A 2.25 Inactive DFGin‑None DFGAsp-rot-in out-out in-in TYR APEdihe_iiiai APEdist_aaaa 03Q Type1.5_Back 706 - 993 0 None M706A,Q711L,M712L Receptor tyrosine-protein kinase erbB-2
TYR ERBB2 ERBB2_HUMAN 3PP0B 2.25 Inactive DFGin‑None DFGAsp-rot-in out-out in-out TYR APEdihe_oiiai APEdist_aaaa 03Q Type1.5_Back 706 - 1009 0 None M706A,Q711L,M712L Receptor tyrosine-protein kinase erbB-2
TYR ERBB2 ERBB2_HUMAN 3RCDA 3.21 Inactive DFGin‑None DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa 03P Type1.5_Back 713 - 1022 0 None None Receptor tyrosine-protein kinase erbB-2
TYR ERBB2 ERBB2_HUMAN 3RCDC 3.21 Inactive DFGin‑None DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa 03P Type1.5_Back 713 - 1022 0 None None Receptor tyrosine-protein kinase erbB-2
TYR ERBB2 ERBB2_HUMAN 8U8XA 1.69 Inactive DFGout‑None DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa W9N Type1 712 - 1024 0 None None Receptor tyrosine-protein kinase erbB-2
TYR ERBB2 ERBB2_HUMAN 8VB5A 1.48 Inactive None‑None DFGAsp-rot-out out-out out-in TYR APEdihe_iiiai APEdist_aaaa A1AAC Type1 706 - 990 0 None None Receptor tyrosine-protein kinase erbB-2
TYR ERBB3 ERBB3_HUMAN 3KEXA 2.797 Pseudo DFGin‑BLBplus DFGAsp-rot-out out-na out-out TYR APEdihe_nnoai APEdist_aaaa ANP ATPlike 698 - 994 0 None None Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 3KEXB 2.797 Pseudo DFGin‑BLBplus DFGAsp-rot-out out-na out-out TYR APEdihe_nnoai APEdist_aaaa ANP ATPlike 698 - 988 0 None None Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 4RIWA 3.1 Pseudo DFGin‑BLBplus DFGAsp-rot-out out-na out-none TYR APEdihe_nnnai APEdist_aaaa ANP ATPlike 699 - 979 0 None None Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 4RIWC 3.1 Pseudo DFGin‑BLBplus DFGAsp-rot-out out-na out-out TYR APEdihe_oioai APEdist_aaaa ANP ATPlike 699 - 979 0 None None Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 3LMGA 2.8 Pseudo DFGin‑BLBplus DFGAsp-rot-out out-na out-out TYR APEdihe_nnoai APEdist_aaaa ANP ATPlike 699 - 978 0 None None Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 3LMGB 2.8 Pseudo DFGin‑BLBplus DFGAsp-rot-out out-na out-none TYR APEdihe_nnnai APEdist_aaaa ANP ATPlike 699 - 978 0 None None Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 4RIYA 2.981 Pseudo DFGin‑BLBplus DFGAsp-rot-out out-na out-none TYR APEdihe_nnnai APEdist_aaaa ANP ATPlike 699 - 979 0 None E928G Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 4RIYC 2.981 Pseudo DFGin‑BLBplus DFGAsp-rot-out out-na out-out TYR APEdihe_oioai APEdist_aaaa ANP ATPlike 699 - 979 0 None E928G Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 4RIXA 3.1 Pseudo DFGin‑BLBplus DFGAsp-rot-out out-na out-none TYR APEdihe_nnnai APEdist_aaaa ANP ATPlike 699 - 979 0 None Q809R Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 4RIXC 3.1 Pseudo DFGin‑BLBplus DFGAsp-rot-out out-na out-out TYR APEdihe_oioai APEdist_aaaa ANP ATPlike 699 - 979 0 None Q809R Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 6OP9A 2.501 Pseudo DFGin‑BLBplus DFGAsp-rot-in out-na out-out TYR APEdihe_oiiai APEdist_aaaa DB8 Type1 699 - 979 0 None None Receptor tyrosine-protein kinase erbB-3
TYR ERBB4 ERBB4_HUMAN AF-Q15303-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 710 - 984 0 None None Receptor tyrosine-protein kinase erbB-4
TYR ERBB4 ERBB4_HUMAN AF-Q15303-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 710 - 984 0 None None Receptor tyrosine-protein kinase erbB-4
TYR ERBB4 ERBB4_HUMAN 3BCEA 2.5 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa No_ligand No_ligand 703 - 991 0 None None Receptor tyrosine-protein kinase erbB-4
TYR ERBB4 ERBB4_HUMAN 3BCEB 2.5 Inactive DFGin‑BLAminus DFGAsp-rot-out in-out in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 703 - 993 0 None None Receptor tyrosine-protein kinase erbB-4
TYR ERBB4 ERBB4_HUMAN 3BCEC 2.5 Inactive DFGin‑BLAminus DFGAsp-rot-out in-out in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 703 - 990 0 None None Receptor tyrosine-protein kinase erbB-4
TYR ERBB4 ERBB4_HUMAN 3BBWA 4.0 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nnnai APEdist_aaaa No_ligand No_ligand 708 - 991 0 None None Receptor tyrosine-protein kinase erbB-4
TYR ERBB4 ERBB4_HUMAN 3BBWB 4.0 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nnnai APEdist_aaaa No_ligand No_ligand 708 - 998 0 None None Receptor tyrosine-protein kinase erbB-4
TYR ERBB4 ERBB4_HUMAN 2R4BA 2.4 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-out TYR APEdihe_oiiai APEdist_aaaa GW7 Type1.5_Back 694 - 991 0 None None Receptor tyrosine-protein kinase erbB-4
TYR ERBB4 ERBB4_HUMAN 2R4BB 2.4 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-out TYR APEdihe_oiiai APEdist_aaaa GW7 Type1.5_Back 694 - 991 0 None None Receptor tyrosine-protein kinase erbB-4
TYR ERBB4 ERBB4_HUMAN 3BBTB 2.8 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nnnai APEdist_aaaa FMM Type1.5_Back 708 - 998 0 None None Receptor tyrosine-protein kinase erbB-4
TYR ERBB4 ERBB4_HUMAN 3BBTD 2.8 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nnnai APEdist_aaaa FMM Type1.5_Back 709 - 988 0 None None Receptor tyrosine-protein kinase erbB-4
TYR FER FER_HUMAN AF-P16591-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 555 - 822 0 None None Tyrosine-protein kinase Fer
TYR FER FER_HUMAN AF-P16591-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 555 - 822 0 None None Tyrosine-protein kinase Fer
TYR FES FES_HUMAN AF-P07332-K1A -1.0 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa No_ligand No_ligand 553 - 822 0 None None Tyrosine-protein kinase Fes/Fps
TYR FES FES_HUMAN AF-P07332-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 553 - 822 0 None None Tyrosine-protein kinase Fes/Fps
TYR FES FES_HUMAN 6JMFA 2.0 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa 9FC Type1 450 - 821 0 None None Tyrosine-protein kinase Fes/Fps
TYR FES FES_HUMAN 3BKBA 1.78 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa STU Type1 449 - 821 0 None None Tyrosine-protein kinase Fes/Fps
TYR FES FES_HUMAN 4E93A 1.84 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa GUI Type1 448 - 822 0 None None Tyrosine-protein kinase Fes/Fps
TYR FES FES_HUMAN 8XKPA 2.05 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa A1LWS Type1 450 - 821 0 None None Tyrosine-protein kinase Fes/Fps
TYR FES FES_HUMAN 3CBLA 1.75 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa STU, STU, STU Type1, Allosteric, Allosteric 448 - 821 0 None None Tyrosine-protein kinase Fes/Fps
TYR FES FES_HUMAN 3CD3A 1.98 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa STU, STU, STU Type1, Allosteric, Allosteric 448 - 821 0 PTR713 None Tyrosine-protein kinase Fes/Fps
TYR FGFR1 FGFR1_HUMAN 3GQIA 2.5 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa ACP ATPlike 464 - 770 0 PTR653,PTR654,PTR766 C488A,Y583F,C584S,Y585F Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 3KXXB 3.2 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 460 - 764 0 None C488A,R577E,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 3KXXC 3.2 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 458 - 762 0 None C488A,R577E,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 3KXXD 3.2 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 458 - 762 0 None C488A,R577E,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5FLFA 2.58 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa No_ligand No_ligand 460 - 762 0 None R675G Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5FLFB 2.58 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa No_ligand No_ligand 460 - 764 0 None R675G Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5FLFC 2.58 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa No_ligand No_ligand 464 - 763 0 None R675G Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5FLFD 2.58 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa No_ligand No_ligand 465 - 763 0 None R675G Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN AF-P11362-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 470 - 764 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN AF-P11362-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 470 - 764 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4RWIA 2.292 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa No_ligand No_ligand 460 - 764 0 None C488A,V561M,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4RWIB 2.292 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa No_ligand No_ligand 461 - 763 0 None C488A,V561M,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 1FGKA 2.0 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa No_ligand No_ligand 464 - 762 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 1FGKB 2.0 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa No_ligand No_ligand 461 - 761 0 None C488A Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4UWYA 2.305 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa No_ligand No_ligand 462 - 762 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4UWYB 2.305 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_nnoai APEdist_aaaa No_ligand No_ligand 459 - 762 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 3KY2A 2.7 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa No_ligand No_ligand 458 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 3KY2B 2.7 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa No_ligand No_ligand 460 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4RWLA 2.193 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa No_ligand No_ligand 465 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5FLFE 2.58 Inactive DFGin‑BLAplus DFGAsp-rot-out in-out none-out TYR APEdihe_iooai APEdist_aaaa No_ligand No_ligand 466 - 761 0 None R675G Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5AM7A 1.957 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 38O Type1 458 - 764 0 None V561M Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5AM7B 1.957 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 38O Type1 458 - 762 0 None V561M Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4RWKA 2.982 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 66T Type1 458 - 764 0 None C488A,V561M,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4ZSAA 2.0 Inactive DFGin‑BLAplus DFGAsp-rot-in in-in out-out TYR APEdihe_iioai APEdist_aaaa 4UT Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4ZSAB 2.0 Inactive DFGin‑BLAplus DFGAsp-rot-in in-in none-out TYR APEdihe_iioai APEdist_aaaa 4UT Type1 462 - 761 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5Z0SA 2.45 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 960 Type1 464 - 762 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5Z0SB 2.45 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 960 Type1 464 - 761 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6ITJA 1.994 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa AXU Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6ITJB 1.994 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa AXU Type1 459 - 761 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 9CD5A 2.939 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa A1AV2 Type1 465 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 9CD5B 2.939 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa A1AV2 Type1 460 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4F63A 2.55 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 0S7 Type1 464 - 762 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4F63B 2.55 Inactive DFGin‑BLAplus DFGAsp-rot-out in-none none-out TYR APEdihe_iioai APEdist_aaaa 0S7 Type1 461 - 761 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4F64A 2.05 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 0S8 Type1 464 - 762 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4F64B 2.05 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa 0S8 Type1 461 - 761 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4NKAA 2.19 Inactive DFGin‑BLAplus DFGAsp-rot-out in-none none-out TYR APEdihe_iioai APEdist_aaaa 2K7 Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4NKSA 2.5 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa 2M2 Type1 465 - 762 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4NKSB 2.5 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa 2M2 Type1 461 - 761 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4UWBA 2.31 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa JVT Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4UWBB 2.31 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa JVT Type1 459 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4UWCA 1.96 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 4Y0 Type1 465 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4UWCB 1.96 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 4Y0 Type1 459 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5O49A 1.91 Inactive DFGin‑BLAplus DFGAsp-rot-out in-out out-out TYR APEdihe_iioai APEdist_aaaa 9K5 Type1 464 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5O49B 1.91 Inactive DFGin‑BLAplus DFGAsp-rot-none in-out none-out TYR APEdihe_iioai APEdist_aaaa 9K5 Type1 460 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5O4AA 2.01 Inactive DFGin‑BLAplus DFGAsp-rot-out in-out out-out TYR APEdihe_iioai APEdist_aaaa 9K8 Type1 464 - 764 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5O4AB 2.01 Inactive DFGin‑BLAplus DFGAsp-rot-out in-out none-out TYR APEdihe_iioai APEdist_aaaa 9K8 Type1 460 - 763 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 7OZBAAA 1.71 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 47I Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 7OZBBBB 1.71 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 47I Type1 460 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 7OZDAAA 1.82 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa 42I Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 7OZDBBB 1.82 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa 42I Type1 460 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 7OZFAAA 1.82 Inactive DFGin‑BLAplus DFGAsp-rot-in in-in none-out TYR APEdihe_iioai APEdist_aaaa 466 Type1 465 - 765 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 7OZFBBB 1.82 Inactive DFGin‑BLAplus DFGAsp-rot-in in-in none-out TYR APEdihe_iioai APEdist_aaaa 466 Type1 460 - 763 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 1AGWA 2.4 Inactive DFGin‑BLAplus DFGAsp-rot-out in-out out-out TYR APEdihe_iioai APEdist_aaaa SU2 Type1 464 - 762 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 1AGWB 2.4 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa SU2 Type1 461 - 761 0 None C488A Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 1FGIA 2.5 Inactive DFGin‑BLAplus DFGAsp-rot-out in-out out-out TYR APEdihe_iioai APEdist_aaaa SU1 Type1 464 - 762 0 None C488A Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 1FGIB 2.5 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa SU1 Type1 461 - 761 0 None C488A Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5AM6A 1.96 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 38O Type1 458 - 765 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5AM6B 1.96 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 38O Type1 458 - 762 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5UQ0A 2.3 Inactive DFGin‑BLAplus DFGAsp-rot-out in-none none-out TYR APEdihe_nnoai APEdist_aaaa WP1 Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5UQ0B 2.3 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_nnoai APEdist_aaaa WP1 Type1 463 - 762 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 3JS2A 2.2 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa VM1 Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 3JS2B 2.2 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa VM1 Type1 459 - 762 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 3GQLC 2.8 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-none TYR APEdihe_nnnai APEdist_aaaa GQL Type1 463 - 766 0 None C488A Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 8JMZA 1.988 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa UKI Type1 460 - 765 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 8JMZB 1.988 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa UKI Type1 458 - 763 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 9U7GA 1.66 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa A1EOH Type1 458 - 764 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 9U7GB 1.66 Inactive DFGin‑BLAplus DFGAsp-rot-out in-out none-out TYR APEdihe_nnoai APEdist_aaaa A1EOH Type1 458 - 763 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 9UHCA 1.88 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa A1EPE Type1 458 - 764 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 9UHCB 1.88 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa A1EPE Type1 458 - 763 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 9UHIA 1.76 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa A1EPF Type1 458 - 764 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 9UHIB 1.76 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa A1EPF Type1 458 - 763 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 9VLJA 1.81 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa A1ESP Type1 458 - 764 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 9VLJB 1.81 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa A1ESP Type1 458 - 763 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5A46A 2.63 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 38O Type1 464 - 766 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5A46B 2.63 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 38O Type1 458 - 766 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4RWKB 2.982 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa 66T Type1.5_Back 459 - 763 0 None C488A,V561M,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 3C4FA 2.07 Inactive DFGin‑BLAplus DFGAsp-rot-out in-out out-out TYR APEdihe_iioai APEdist_aaaa C4F Type1.5_Back 464 - 765 0 None C488A Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 3C4FB 2.07 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa C4F Type1.5_Back 464 - 765 0 None C488A Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 3RHXA 2.01 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 3RH Type1.5_Back 464 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 3RHXB 2.01 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa 3RH Type1.5_Back 461 - 761 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5A4CA 2.09 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa XOJ Type1.5_Back 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5A4CB 2.09 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa XOJ Type1.5_Back 461 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4NK9B 2.57 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa 2K5 Type1.5_Back 460 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4V05A 2.57 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 66T Type1.5_Back 464 - 765 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4V05B 2.57 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa 66T Type1.5_Back 459 - 764 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5EW8A 1.63 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 5SF Type1.5_Back 464 - 765 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5EW8B 1.63 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 5SF Type1.5_Back 461 - 765 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 2FGIA 2.5 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa PD1 Type1.5_Back 464 - 762 0 None L457V,C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 2FGIB 2.5 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa PD1 Type1.5_Back 461 - 761 0 None L457V,C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5B7VA 2.15 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa LWJ Type1.5_Back 464 - 763 0 None L457V,C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4WUNA 1.65 Inactive DFGin‑BLAplus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa 66T Type1.5_Back 465 - 765 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4WUNB 1.65 Inactive DFGin‑BLAplus DFGAsp-rot-in in-in none-out TYR APEdihe_nnoai APEdist_aaaa 66T Type1.5_Back 461 - 762 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5UR1A 2.2 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa YY9 Type1.5_Back 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6C18A 2.3 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa YY5 Type1.5_Back 465 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6C19A 2.12 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_nnoai APEdist_aaaa YY7 Type1.5_Back 464 - 765 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6C19B 2.12 Inactive DFGin‑BLAplus DFGAsp-rot-in in-in none-out TYR APEdihe_nnoai APEdist_aaaa YY7 Type1.5_Back 464 - 762 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6C1BA 2.0 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa YY4 Type1.5_Back 465 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6C1BB 2.0 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_nnoai APEdist_aaaa YY4 Type1.5_Back 463 - 762 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6C1CA 2.15 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa YY6 Type1.5_Back 465 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6C1CB 2.15 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_nnoai APEdist_aaaa YY6 Type1.5_Back 463 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6C1OA 2.29 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_nnoai APEdist_aaaa MK9 Type1.5_Back 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6C1OB 2.29 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa MK9 Type1.5_Back 464 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6MZQA 2.0 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa TZ0 Type1.5_Back 464 - 765 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6MZQB 2.0 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa TZ0 Type1.5_Back 462 - 761 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4RWJA 2.489 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 66T Type1.5_Back 458 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4RWJB 2.489 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa 66T Type1.5_Back 459 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 3GQLA 2.8 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_oooai APEdist_aaaa GQL Type1.5_Back 463 - 774 0 None C488A Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 3TT0A 2.8 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 07J Type1.5_Back 461 - 765 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 3TT0B 2.8 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_nnnao APEdist_aaaa 07J Type1.5_Back 459 - 763 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 8Y22A 2.792 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa A1LW9 Type1.5_Back 459 - 762 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 8Y22B 2.792 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa A1LW9 Type1.5_Back 463 - 765 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6NVLA 2.7 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa XL6 Type1.5_Back 463 - 765 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6NVLB 2.7 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa XL6 Type1.5_Back 461 - 761 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6NVLC 2.7 Inactive DFGin‑BLAplus DFGAsp-rot-none in-in none-none TYR APEdihe_nnnai APEdist_aaaa XL6 Type1.5_Back 465 - 761 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6NVLD 2.7 Inactive DFGin‑BLAplus DFGAsp-rot-out in-none none-out TYR APEdihe_iioai APEdist_aaaa XL6 Type1.5_Back 471 - 762 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 7WCLA 2.495 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 8ZF Type1.5_Back 459 - 764 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 7WCLB 2.495 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa 8ZF Type1.5_Back 458 - 763 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 8XLOA 2.36 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa A1LVQ Type1.5_Back 462 - 764 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 8XLOB 2.36 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa A1LVQ Type1.5_Back 458 - 763 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 8XZ7B 1.75 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa A1LWW Type1.5_Back 461 - 765 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6MZWA 2.2 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa TZ0 Type1.5_Back 464 - 765 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5VNDA 2.2 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 9ES Type1.5_Back 463 - 765 0 None C488A,Y563C,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5VNDB 2.2 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 9ES Type1.5_Back 460 - 765 0 None C488A,Y563C,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6P68A 2.9 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa O1Y Type1.5_Back 462 - 763 0 None C488A,Y563C Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6P68B 2.9 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa O1Y Type1.5_Back 462 - 763 0 None C488A,Y563C Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6P68C 2.9 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa O1Y Type1.5_Back 463 - 763 0 None C488A,Y563C Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6P69A 2.2 Inactive DFGin‑BLAplus DFGAsp-rot-in in-in out-out TYR APEdihe_iioai APEdist_aaaa O21 Type1.5_Back 462 - 765 0 None C488A,Y563C Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6P69B 2.2 Inactive DFGin‑BLAplus DFGAsp-rot-in in-in out-out TYR APEdihe_iioai APEdist_aaaa O21 Type1.5_Back 461 - 762 0 None C488A,Y563C Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 3KXXA 3.2 Inactive DFGin‑BLBminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa No_ligand No_ligand 461 - 765 0 None C488A,R577E,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 8JQIB 4.1 Inactive DFGin‑BLBplus DFGAsp-rot-out in-in out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 463 - 769 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 8YKIA 2.79 Inactive DFGin‑BLBplus DFGAsp-rot-out in-in none-out TYR APEdihe_nnoai APEdist_aaaa A1LY1 Type1 464 - 762 0 None C488A Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 8YKIB 2.79 Inactive DFGin‑BLBplus DFGAsp-rot-out in-in none-out TYR APEdihe_nnoai APEdist_aaaa A1LY1 Type1 461 - 761 0 None C488A Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 3GQLB 2.8 Inactive DFGin‑BLBplus DFGAsp-rot-out in-in out-none TYR APEdihe_nnnai APEdist_aaaa GQL Type1 463 - 765 0 None C488A Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 8XZ7A 1.75 Inactive DFGin‑BLBplus DFGAsp-rot-in in-in none-out TYR APEdihe_iioai APEdist_aaaa A1LWW Type1 458 - 765 0 None C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5ZV2A 2.86 Inactive DFGin‑BLBplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa LEV Type1.5_Back 463 - 762 0 None C488A Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5ZV2B 2.86 Inactive DFGin‑BLBplus DFGAsp-rot-out in-in none-out TYR APEdihe_nioai APEdist_aaaa LEV Type1.5_Back 461 - 764 0 None C488A Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4NK9A 2.57 Inactive DFGin‑BLBplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa 2K5 Type1.5_Back 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5B7VB 2.15 Inactive DFGin‑BLBplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa LWJ Type1.5_Back 462 - 762 0 None L457V,C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5UR1B 2.2 Inactive DFGin‑BLBplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa YY9 Type1.5_Back 464 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4RWLB 2.193 Inactive DFGin‑BLBplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa 3ZC Type1.5_Back 458 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4F65A 2.26 Inactive DFGin‑None DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa 0S9 Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4NKAB 2.19 Inactive DFGin‑None DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa 2K7 Type1 458 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4F65B 2.26 Inactive DFGin‑None DFGAsp-rot-in in-in none-out TYR APEdihe_iioai APEdist_aaaa 0S9 Type1.5_Back 460 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6C18B 2.3 Inactive DFGin‑None DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa YY5 Type1.5_Back 466 - 762 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 6MZWB 2.2 Inactive DFGin‑None DFGAsp-rot-none in-in none-none TYR APEdihe_nnnai APEdist_aaaa TZ0 Type1.5_Back 463 - 762 0 None None Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4V04B 2.12 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-out TYR APEdihe_iioai APEdist_aaaa 0LI Type2 458 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4V01A 2.33 Inactive DFGout‑None DFGAsp-rot-in in-in none-out TYR APEdihe_iioai APEdist_aaaa 0LI Type2 465 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4V01B 2.33 Inactive DFGout‑None DFGAsp-rot-in in-in none-out TYR APEdihe_iioai APEdist_aaaa 0LI Type2 461 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 4V04A 2.12 Inactive DFGout‑None DFGAsp-rot-in in-in none-out TYR APEdihe_iioai APEdist_aaaa 0LI Type2 463 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR2 FGFR2_HUMAN 2PWLA 2.4 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa ACP ATPlike 467 - 764 0 None C491A,N549H Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 2PWLB 2.4 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa ACP ATPlike 468 - 765 0 None C491A,N549H Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 5UGLA 1.861 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa ANP ATPlike 468 - 764 0 None D650V Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 5UGLB 1.861 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa ANP ATPlike 467 - 764 0 None D650V Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J96B 2.297 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-out TYR APEdihe_oiiai APEdist_aaaa ACP ATPlike 462 - 766 0 None C491A,K659M Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J98B 2.307 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa ACP ATPlike 461 - 764 0 None C491A,K659Q Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 2PVFA 1.8 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa ACP ATPlike 467 - 765 0 PTR586,PTR656,PTR657 C491A Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 3CLYA 2.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa ACP ATPlike 468 - 772 0 PTR656,PTR657 C491A Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J99A 1.847 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa ACP ATPlike 466 - 764 0 None C491A,K659T Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J99B 1.847 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa ACP ATPlike 467 - 764 0 None C491A,K659T Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J99C 1.847 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa ACP ATPlike 467 - 764 0 None C491A,K659T Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J99D 1.847 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa ACP ATPlike 465 - 764 0 None C491A,K659T Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 2PVYA 2.2 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa ACP ATPlike 467 - 764 0 None C491A,K659N Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 2PVYB 2.2 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa ACP ATPlike 462 - 764 0 None C491A,K659N Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 2PVYC 2.2 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa ACP ATPlike 462 - 764 0 None C491A,K659N Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 2PVYD 2.2 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa ACP ATPlike 467 - 764 0 None C491A,K659N Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J95A 2.377 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa ACP ATPlike 467 - 764 0 None C491A,K659N Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J95B 2.377 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa ACP ATPlike 468 - 764 0 None C491A,K659N Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J95C 2.377 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa ACP ATPlike 468 - 764 0 None C491A,K659N Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J95D 2.377 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa ACP ATPlike 467 - 764 0 None C491A,K659N Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 2PZ5A 2.4 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa ACP ATPlike 468 - 766 0 None C491A,N549T Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 2PZ5B 2.4 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa ACP ATPlike 468 - 766 0 None C491A,N549T Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J97A 2.548 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa ACP ATPlike 468 - 764 0 None C491A,K659E Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J97B 2.548 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa ACP ATPlike 468 - 764 0 None C491A,K659E Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J97C 2.548 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa ACP ATPlike 467 - 764 0 None C491A,K659E Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J97D 2.548 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa ACP ATPlike 466 - 764 0 None C491A,K659E Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 2PZPA 2.4 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa ACP ATPlike 468 - 766 0 None C491A,K526E Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 2PZPB 2.4 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa ACP ATPlike 468 - 766 0 None C491A,K526E Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 2PZRA 3.0 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa ACP ATPlike 468 - 765 0 None C491A,K641R Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 2PZRB 3.0 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa ACP ATPlike 467 - 766 0 None C491A,K641R Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 5UHNA 2.909 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa ACP ATPlike 469 - 764 0 None N549H,E565A Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 5UHNB 2.909 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa ACP ATPlike 469 - 764 0 None N549H,E565A Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 5UGXA 2.349 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa ACP ATPlike 468 - 764 0 None C491A,E565A Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 5UGXB 2.349 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa ACP ATPlike 468 - 764 0 None C491A,E565A Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 5UI0B 2.05 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa ACP ATPlike 462 - 765 0 None C491A,E565A Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 2Q0BA 2.9 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa ACP ATPlike 468 - 765 0 None C491A,E565A Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 2Q0BB 2.9 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa ACP ATPlike 468 - 766 0 None C491A,E565A Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 2PY3A 2.3 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa ACP ATPlike 468 - 766 0 None C491A,E565G Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 2PY3B 2.3 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa ACP ATPlike 468 - 766 0 None C491A,E565G Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 5EG3A 2.606 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa ACP ATPlike 466 - 774 0 PTR769 Y466F,C491A,E565A,Y586L,Y588P,Y656F,Y657F,K659E Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 6V6QA 2.46 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa ACP ATPlike 466 - 765 0 PTR656 Y466F,Y561F,Y566F,Y575F,Y586F,Y588F,Y608F,Y616F,Y657F,Y733F Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 6V6QB 2.46 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa ACP ATPlike 467 - 766 0 PTR656 Y466F,Y561F,Y566F,Y575F,Y586F,Y588F,Y608F,Y616F,Y657F,Y733F Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 6V6QD 2.46 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa ACP ATPlike 467 - 765 0 PTR656 Y466F,Y561F,Y566F,Y575F,Y586F,Y588F,Y608F,Y616F,Y657F,Y733F Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8SWEA 2.24 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa GSH, WXQ Allosteric, Type1 468 - 765 0 None None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J96A 2.297 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa No_ligand No_ligand 461 - 766 0 None C491A,K659M Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 4J98A 2.307 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa No_ligand No_ligand 461 - 764 0 None C491A,K659Q Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN AF-P21802-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 473 - 767 0 None None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN AF-P21802-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 473 - 767 0 None None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 1GJOA 2.4 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa No_ligand No_ligand 467 - 764 0 None None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 5UI0A 2.05 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa No_ligand No_ligand 461 - 766 0 None C491A,E565A Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 2PSQA 2.4 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa No_ligand No_ligand 468 - 765 0 None None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 2PSQB 2.4 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa No_ligand No_ligand 467 - 766 0 None None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 3B2TA 1.8 Inactive DFGin‑BLAminus DFGAsp-rot-out in-out in-out TYR APEdihe_oiiai APEdist_aaaa M33 Type1 464 - 768 0 None A628T,E767Q Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 3B2TB 1.8 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa M33 Type1 458 - 764 0 None A628T,E767Q Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 7OZYAAA 2.28 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 47I Type1 467 - 762 0 None None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 7OZYBBB 2.28 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 47I Type1 467 - 762 0 None None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 9U7EA 2.2 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa A1EOH Type1 467 - 763 0 None None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 9U7EB 2.2 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa A1EOH Type1 467 - 763 0 None None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 9U7SA 1.99 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa A1EOJ Type1 467 - 764 0 None None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 9U7SB 1.99 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa A1EOJ Type1 467 - 763 0 None None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8H75A 3.75 Inactive DFGin‑BLAminus DFGAsp-rot-out in-out in-in TYR APEdihe_iiiai APEdist_aaaa KX0 Type1 467 - 765 0 PTR656 None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8H75B 3.75 Inactive DFGin‑BLAminus DFGAsp-rot-out in-out in-out TYR APEdihe_oiiai APEdist_aaaa KX0 Type1 467 - 764 0 PTR656 None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8H75C 3.75 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in out-out TYR APEdihe_oiiai APEdist_aaaa KX0 Type1 467 - 763 0 PTR656 None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8H75D 3.75 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-out TYR APEdihe_oiiai APEdist_aaaa KX0 Type1 467 - 764 0 PTR656 None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 6LVKA 2.29 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa EVC Type1 468 - 766 0 PTR561 None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 6LVKB 2.29 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa EVC Type1 468 - 765 0 PTR561 None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 6LVLA 2.98 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa EVL Type1 468 - 766 0 None None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 6LVLB 2.98 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa EVL Type1 468 - 765 0 None None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 3RI1B 2.1 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 3RH Type1 468 - 766 0 None None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 1OECA 2.4 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa AA2 Type1 467 - 765 0 None None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8SWEB 2.24 Inactive DFGin‑BLAminus DFGAsp-rot-out in-out in-out TYR APEdihe_oiiai APEdist_aaaa WXQ Type1 468 - 767 0 None None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 7KIAA 2.22 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa WFD Type1 467 - 764 0 None V564F Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 7KIAB 2.22 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa WFD Type1 467 - 767 0 None V564F Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 7KIEA 2.47 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa WF7 Type1 466 - 766 0 None V564F Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 7KIEB 2.47 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa WF7 Type1 466 - 767 0 None V564F Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8W3BA 2.23 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa TZ0 Type1.5_Back 467 - 764 0 None D650V Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8W3BB 2.23 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa TZ0 Type1.5_Back 467 - 764 0 None D650V Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8W3BC 2.23 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa TZ0 Type1.5_Back 467 - 764 0 None D650V Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8W3BD 2.23 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa TZ0 Type1.5_Back 465 - 764 0 None D650V Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8W3DA 2.04 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa TZ0 Type1.5_Back 467 - 764 0 None N549K,D650V Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8W3DB 2.04 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa TZ0 Type1.5_Back 463 - 764 0 None N549K,D650V Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8W3DC 2.04 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa TZ0 Type1.5_Back 467 - 766 0 None N549K,D650V Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8W3DD 2.04 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa TZ0 Type1.5_Back 463 - 765 0 None N549K,D650V Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 6AGXA 2.95 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-in TYR APEdihe_iiiai APEdist_aaaa 9WX Type1.5_Back 467 - 764 0 PTR586,PTR588,PTR656,PTR657 A628T Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 6AGXB 2.95 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-out TYR APEdihe_oiiai APEdist_aaaa 9WX Type1.5_Back 467 - 764 0 PTR586,PTR588,PTR656,PTR657 A628T Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 6AGXC 2.95 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-in TYR APEdihe_iiiai APEdist_aaaa 9WX Type1.5_Back 467 - 764 0 PTR586,PTR588,PTR656,PTR657 A628T Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 6AGXD 2.95 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-out TYR APEdihe_oiiai APEdist_aaaa 9WX Type1.5_Back 467 - 764 0 PTR586,PTR588,PTR656,PTR657 A628T Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 3RI1A 2.1 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 3RH Type1.5_Back 468 - 765 0 None None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8W38A 2.6 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa TZ0 Type1.5_Back 467 - 764 0 None N549D,D650V Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8W38B 2.6 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa TZ0 Type1.5_Back 467 - 764 0 None N549D,D650V Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8W38C 2.6 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa TZ0 Type1.5_Back 465 - 764 0 None N549D,D650V Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8W38D 2.6 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa TZ0 Type1.5_Back 467 - 764 0 None N549D,D650V Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8E1XA 2.68 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa U9P Type1 468 - 762 0 PTR561,PTR586 None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8E1XB 2.68 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa U9P Type1 467 - 765 0 PTR561,PTR586 None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 9VLMA 2.26 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa A1ESP Type1 465 - 763 0 None None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 9VLMB 2.26 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-none TYR APEdihe_nniai APEdist_aaaa A1ESP Type1 465 - 763 0 None None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8STGA 3.79 Inactive DFGin‑BLAplus DFGAsp-rot-out in-out none-none TYR APEdihe_niiai APEdist_aaaa WCJ Type1 461 - 764 0 None None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 9U3NA 3.25 Inactive DFGin‑BLAplus DFGAsp-rot-out in-out none-in TYR APEdihe_iiiai APEdist_aaaa A1ENT Type1 461 - 764 0 None V564F Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8W2XA 2.98 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa A1AFR Type1.5_Back 458 - 765 0 None None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8W2XB 2.98 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa A1AFR Type1.5_Back 458 - 765 0 None None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8U1FA 3.33 Inactive DFGin‑BLAplus DFGAsp-rot-out in-out none-none TYR APEdihe_niiai APEdist_aaaa UIM Type1.5_Back 460 - 764 0 None None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 6V6QC 2.46 Inactive DFGin‑BLBminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa ACP ATPlike 467 - 766 0 PTR656 Y466F,Y561F,Y566F,Y575F,Y586F,Y588F,Y608F,Y616F,Y657F,Y733F Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8U1FB 3.33 Inactive DFGin‑None DFGAsp-rot-out in-out none-none TYR APEdihe_nniai APEdist_aaaa UIM Type1.5_Back 472 - 765 0 None None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8STGB 3.79 Inactive DFGin‑None DFGAsp-rot-in in-out none-out TYR APEdihe_oiiai APEdist_aaaa WCJ Type1.5_Back 472 - 765 0 None None Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 9U3NB 3.25 Inactive DFGin‑None DFGAsp-rot-out in-in none-in TYR APEdihe_iiiai APEdist_aaaa A1ENT Type1.5_Back 470 - 764 0 None V564F Fibroblast growth factor receptor 2
TYR FGFR3 FGFR3_HUMAN 4K33A 2.341 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa ACP ATPlike 459 - 755 0 None C482A,C582S,K650E Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN AF-P22607-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 464 - 758 0 None None Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN AF-P22607-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 464 - 758 0 None None Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 9KFUA 1.4 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa A1L5T Type1 448 - 756 0 None None Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 6LVMA 2.53 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa EVR Type1.5_Back 472 - 755 0 PTR577,PTR647,PTR648 None Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 7DHLA 2.57 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa H6X Type1.5_Back 472 - 755 0 PTR577,PTR647,PTR648 None Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 8UDUB 1.737 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa WIQ Type1.5_Front 459 - 755 0 None P572S,P573G Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 6PNXA 2.199 Inactive DFGin‑BLAplus DFGAsp-rot-out in-out out-out TYR APEdihe_oiiai APEdist_aaaa ACP ATPlike 456 - 757 0 None C482A,C582S,R669E Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 6PNXB 2.199 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_oiiai APEdist_aaaa ACP ATPlike 455 - 756 0 None C482A,C582S,R669E Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 8UDTA 2.829 Inactive DFGin‑BLAplus DFGAsp-rot-out in-out out-out TYR APEdihe_nnoai APEdist_aaaa MLT, MLT, WGF Allosteric, Allosteric, Type1.5_Front 457 - 756 0 None P572S,P573G Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 9VM9A 2.65 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa A1ESW Type1 456 - 756 0 None None Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 9VM9B 2.65 Inactive DFGin‑BLAplus DFGAsp-rot-out in-out out-out TYR APEdihe_iioai APEdist_aaaa A1ESW Type1 457 - 755 0 None None Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 9VM9C 2.65 Inactive DFGin‑BLAplus DFGAsp-rot-out in-out out-out TYR APEdihe_iioai APEdist_aaaa A1ESW Type1 462 - 756 0 None None Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 9VM9D 2.65 Inactive DFGin‑BLAplus DFGAsp-rot-out in-none out-out TYR APEdihe_iioai APEdist_aaaa A1ESW Type1 459 - 756 0 None None Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 9VMBA 1.97 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa A1ESX Type1 456 - 756 0 None None Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 9VMBB 1.97 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa A1ESX Type1 456 - 756 0 None None Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 9VMBC 1.97 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa A1ESX Type1 457 - 756 0 None None Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 9VMBD 1.97 Inactive DFGin‑BLAplus DFGAsp-rot-out in-out out-out TYR APEdihe_iioai APEdist_aaaa A1ESX Type1 462 - 756 0 None None Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 9D1XA 1.6 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa A1A6M Type1 461 - 754 0 None P572S,P573G Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 9CD7A 2.53 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_nnoai APEdist_aaaa A1AV2 Type1 451 - 755 0 None C482A,C582S,K650E Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 9CD7B 2.53 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_nnoai APEdist_aaaa A1AV2 Type1 458 - 755 0 None C482A,C582S,K650E Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 9CD7C 2.53 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_nnoai APEdist_aaaa A1AV2 Type1 458 - 755 0 None C482A,C582S,K650E Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 8UDVA 2.348 Inactive DFGin‑BLAplus DFGAsp-rot-in in-in out-out TYR APEdihe_iioai APEdist_aaaa WIQ Type1.5_Back 458 - 755 0 None V555M Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 8UDVB 2.348 Inactive DFGin‑BLAplus DFGAsp-rot-in in-in out-out TYR APEdihe_iioai APEdist_aaaa WIQ Type1.5_Back 455 - 755 0 None V555M Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 8UDVC 2.348 Inactive DFGin‑BLAplus DFGAsp-rot-in in-in none-out TYR APEdihe_nnoai APEdist_aaaa WIQ Type1.5_Back 458 - 755 0 None V555M Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 8UDTB 2.829 Inactive DFGin‑BLAplus DFGAsp-rot-out in-out out-out TYR APEdihe_nooai APEdist_aaaa WGF Type1.5_Front 457 - 754 0 None P572S,P573G Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 8UDTC 2.829 Inactive DFGin‑BLAplus DFGAsp-rot-out in-out out-out TYR APEdihe_nooai APEdist_aaaa WGF Type1.5_Front 457 - 756 0 None P572S,P573G Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 8UDUA 1.737 Inactive DFGin‑BLBplus DFGAsp-rot-in in-in none-in TYR APEdihe_iiiai APEdist_aaaa WIQ Type1.5_Back 460 - 756 0 None P572S,P573G Fibroblast growth factor receptor 3
TYR FGFR4 FGFR4_HUMAN AF-P22455-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 459 - 753 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN AF-P22455-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 459 - 753 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 4QQJA 1.682 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa No_ligand No_ligand 454 - 752 0 None C477A,V550L,R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 4QQTA 1.501 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa No_ligand No_ligand 454 - 750 0 None C477A,R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 4TYGA 2.4 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 447 - 751 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 7WCXA 2.175 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 90F Type1 453 - 752 0 None C477A,R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 7YBXA 2.233 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa IH7 Type1 453 - 752 0 None V550M,R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 7WCWA 2.317 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 90F Type1 453 - 752 0 None C477A,R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 7YBPA 2.243 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa IH7 Type1 453 - 752 0 None V550L,R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 8KH8A 1.49 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa VVW Type1 453 - 751 0 None C477A,V550L,R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 6JPJA 2.638 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa FGF Type1 454 - 752 0 None C477A,R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 9K0IA 2.236 Inactive DFGin‑BLAplus DFGAsp-rot-out in-out out-out TYR APEdihe_iioai APEdist_aaaa A1EEW Type1 453 - 752 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 9K0JA 2.068 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa A1EEX Type1 453 - 752 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 8W5CA 2.3 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nniai APEdist_aaaa VZO Type1 453 - 752 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 8W5CB 2.3 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nniai APEdist_aaaa VZO Type1 453 - 752 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 7VJLA 2.9 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa 7IF Type1 454 - 753 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 7VJLB 2.9 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa 7IF Type1 453 - 753 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 6YI8A 2.13 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_niiai APEdist_aaaa FGF Type1 453 - 753 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 6YI8B 2.13 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nniai APEdist_aaaa FGF Type1 451 - 752 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 5NUDA 2.5 Inactive DFGin‑BLAplus DFGAsp-rot-out in-none none-none TYR APEdihe_niiai APEdist_aaaa 99K Type1 453 - 753 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 4TYIA 3.4 Inactive DFGin‑BLAplus DFGAsp-rot-out in-out out-none TYR APEdihe_nniai APEdist_aaaa 38O Type1 447 - 750 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 7WCTA 2.106 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 90F Type1 453 - 752 0 None R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 7YBOA 2.307 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa IH7 Type1 453 - 752 0 None R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 7YC1A 2.535 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa IIQ Type1 453 - 752 0 None R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 7YC3A 1.987 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa IIW Type1 453 - 752 0 None R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 8KH6A 1.62 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa VVI Type1 454 - 750 0 None R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 8KH7A 1.52 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa VVW Type1 454 - 751 0 None R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 6IUOA 2.3 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_nnoai APEdist_aaaa AWX Type1 445 - 750 0 None R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 6IUPA 2.0 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa AX0 Type1 452 - 750 0 None R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 4XCUA 1.71 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 40M Type1.5_Back 453 - 751 0 None L449M Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 6NVGA 1.99 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa XL8 Type1.5_Back 453 - 751 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 6NVHA 1.9 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-none TYR APEdihe_nniai APEdist_aaaa XL6 Type1.5_Back 453 - 750 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 6NVIA 2.117 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-none TYR APEdihe_nniai APEdist_aaaa XL7 Type1.5_Back 453 - 750 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 6NVJA 2.3 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa XL5 Type1.5_Back 453 - 751 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 6NVKA 2.3 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa XL9 Type1.5_Back 453 - 750 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 6V9CA 1.9 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa QS7 Type1.5_Back 453 - 751 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 7DTZA 2.01 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa HHL Type1.5_Back 453 - 751 0 None C477A,R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 6JPEA 1.601 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa BYU Type1.5_Back 452 - 751 0 None C477A,R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 5NWZB 2.37 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_niiai APEdist_aaaa 9CT Type1.5_Back 454 - 752 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 7F3MA 2.289 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa GX3 Type1.5_Back 453 - 753 0 None R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 7V29A 1.983 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 5JR Type1.5_Back 454 - 750 0 None R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 7V29B 1.983 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 5JR Type1.5_Back 454 - 750 0 None R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 8XLQA 1.95 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa A1LVQ Type1.5_Back 453 - 751 0 None R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 4QQCA 2.4 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_nnoai APEdist_aaaa 37O Type1.5_Back 445 - 750 0 None R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 8KH9A 1.42 Inactive DFGin‑BLBplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa VVW Type1 454 - 752 0 None C477A,V550M,R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 5NWZA 2.37 Inactive DFGin‑BLBplus DFGAsp-rot-out in-out none-none TYR APEdihe_nniai APEdist_aaaa 9CT Type1.5_Back 454 - 752 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 4TYEA 2.8 Inactive DFGin‑None DFGAsp-rot-in in-in out-none TYR APEdihe_nniai APEdist_aaaa No_ligand No_ligand 451 - 753 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 5XFJA 3.25 Inactive DFGin‑None DFGAsp-rot-out in-out none-none TYR APEdihe_nniai APEdist_aaaa 6LF Type1 453 - 750 0 None V550M Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 5XFFA 2.7 Inactive DFGin‑None DFGAsp-rot-out in-in none-none TYR APEdihe_nniai APEdist_aaaa 6LF Type1 453 - 750 0 None V550L Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 5JKGA 2.352 Inactive DFGin‑None DFGAsp-rot-out in-in none-none TYR APEdihe_nniai APEdist_aaaa 6LF Type1 453 - 750 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 4QQ5A 2.203 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-out TYR APEdihe_nnoai APEdist_aaaa 37O Type1.5_Back 445 - 750 0 None V550L,R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 4R6VA 2.353 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa FI3 Type1.5_Back 445 - 750 0 None V550L,R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 4UXQA 1.85 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-out TYR APEdihe_iioai APEdist_aaaa 0LI Type2 452 - 750 0 None C477A Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 4TYJA 2.45 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-none TYR APEdihe_nniai APEdist_aaaa 0LI Type2 447 - 753 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 4QRCA 1.901 Inactive DFGout‑None DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 0LI Type2 454 - 750 0 None C477A,R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 5NUDB 2.5 Inactive None‑None DFGAsp-rot-none in-in none-none TYR APEdihe_niiai APEdist_aaaa 99K Type1 449 - 750 0 None None Fibroblast growth factor receptor 4
TYR FGR FGR_HUMAN AF-P09769-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 255 - 522 0 None None Tyrosine-protein kinase Fgr
TYR FGR FGR_HUMAN AF-P09769-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 255 - 522 0 None None Tyrosine-protein kinase Fgr
TYR FGR FGR_HUMAN 7UY0A 2.55 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-in TYR APEdihe_iiiai APEdist_aaaa VSE Type1.5_Back 80 - 527 0 PTR523 Q524E,P525E,G526I,D527P Tyrosine-protein kinase Fgr
TYR FGR FGR_HUMAN 7UY0B 2.55 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-in TYR APEdihe_iiiai APEdist_aaaa VSE Type1.5_Back 80 - 527 0 PTR523 Q524E,P525E,G526I,D527P Tyrosine-protein kinase Fgr
TYR FGR FGR_HUMAN 7UY3A 2.99 Inactive DFGout‑None DFGAsp-rot-in in-in out-none TYR APEdihe_nniai APEdist_aaaa OJL Type2 135 - 527 0 PTR523 Q524E,P525E,G526I,D527P Tyrosine-protein kinase Fgr
TYR FLT1 VGFR1_HUMAN AF-P17948-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 819 - 1164 0 None None Vascular endothelial growth factor receptor 1
TYR FLT1 VGFR1_HUMAN AF-P17948-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 819 - 1164 0 None None Vascular endothelial growth factor receptor 1
TYR FLT1 VGFR1_HUMAN 3HNGA 2.7 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 8ST Type2 803 - 1158 0 None None Vascular endothelial growth factor receptor 1
TYR FLT3 FLT3_HUMAN AF-P36888-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 602 - 953 0 None None Receptor-type tyrosine-protein kinase FLT3
TYR FLT3 FLT3_HUMAN AF-P36888-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 602 - 953 0 None None Receptor-type tyrosine-protein kinase FLT3
TYR FLT3 FLT3_HUMAN 4XUFA 3.2 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa P30 Type2 600 - 947 0 None None Receptor-type tyrosine-protein kinase FLT3
TYR FLT3 FLT3_HUMAN 4XUFB 3.2 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa P30 Type2 600 - 946 0 None None Receptor-type tyrosine-protein kinase FLT3
TYR FLT3 FLT3_HUMAN 4RT7A 3.1 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa P30 Type2 599 - 950 0 None None Receptor-type tyrosine-protein kinase FLT3
TYR FLT3 FLT3_HUMAN 1RJBA 2.1 Inactive DFGout‑None DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 572 - 947 0 None None Receptor-type tyrosine-protein kinase FLT3
TYR FLT3 FLT3_HUMAN 6JQRA 2.2 Inactive DFGout‑None DFGAsp-rot-in in-in none-in TYR APEdihe_iiiai APEdist_aaaa C6F Type1 571 - 951 0 None None Receptor-type tyrosine-protein kinase FLT3
TYR FLT3 FLT3_HUMAN 8XB1A 2.85 Inactive DFGout‑None DFGAsp-rot-in in-in none-in TYR APEdihe_iiiai APEdist_aaaa ZX3 Type1 573 - 950 0 None None Receptor-type tyrosine-protein kinase FLT3
TYR FLT3 FLT3_HUMAN 5X02A 2.401 Inactive DFGout‑None DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa F6M Type1 573 - 947 0 None None Receptor-type tyrosine-protein kinase FLT3
TYR FLT3 FLT3_HUMAN 6IL3A 2.5 Inactive DFGout‑None DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa A9R Type1 569 - 947 0 None None Receptor-type tyrosine-protein kinase FLT3
TYR FLT4 VGFR3_HUMAN AF-P35916-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 837 - 1179 0 None None Vascular endothelial growth factor receptor 3
TYR FLT4 VGFR3_HUMAN AF-P35916-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 837 - 1179 0 None None Vascular endothelial growth factor receptor 3
TYR FRK FRK_HUMAN AF-P42685-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 226 - 497 0 None None Tyrosine-protein kinase FRK
TYR FRK FRK_HUMAN AF-P42685-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 226 - 497 0 None None Tyrosine-protein kinase FRK
TYR FYN FYN_HUMAN AF-P06241-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 263 - 530 0 None None Tyrosine-protein kinase Fyn
TYR FYN FYN_HUMAN AF-P06241-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 263 - 530 0 None None Tyrosine-protein kinase Fyn
TYR FYN FYN_HUMAN 2DQ7X 2.8 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa STU Type1 261 - 523 0 PTR420 None Tyrosine-protein kinase Fyn
TYR HCK HCK_HUMAN 1AD5A 2.6 Inactive DFGin‑BLAminus DFGAsp-rot-out out-out out-out TYR APEdihe_iioai APEdist_aaaa ANP ATPlike 79 - 526 0 PTR522 None Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 1AD5B 2.6 Inactive DFGin‑BLAminus DFGAsp-rot-out out-out out-out TYR APEdihe_iioai APEdist_aaaa ANP ATPlike 79 - 526 0 PTR522 None Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN AF-P08631-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 254 - 521 0 None None Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN AF-P08631-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 254 - 521 0 None None Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 2HCKA 3.0 Inactive DFGin‑BLAminus DFGAsp-rot-out out-out out-out TYR APEdihe_oioai APEdist_aaaa QUE Type1 79 - 526 0 PTR522 None Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 2HCKB 3.0 Inactive DFGin‑BLAminus DFGAsp-rot-out out-out out-out TYR APEdihe_oioao APEdist_aaaa QUE Type1 79 - 526 0 PTR522 None Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 2HK5A 2.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 1BM Type1.5_Back 247 - 514 0 None None Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 5ZJ6A 1.696 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa VSE Type1 248 - 518 0 None None Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 1QCFA 2.0 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa PP1 Type1 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 3VS2A 2.609 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nnnai APEdist_aaaa VSB Type1 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 3VS5A 2.851 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nnnai APEdist_aaaa VSG Type1 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 3VS5B 2.851 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nnnai APEdist_aaaa VSG Type1 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 3VS7B 3.001 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nnnai APEdist_aaaa KS1 Type1 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 4LUDA 2.85 Inactive DFGin‑BLBplus DFGAsp-rot-none out-out out-none TYR APEdihe_nnnai APEdist_aaaa SK8 Type1 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 4LUDB 2.85 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nnnai APEdist_aaaa SK8 Type1 81 - 524 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 5H0GA 1.8 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa OOU Type1 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 5ZJ6B 1.696 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa VSE Type1.5_Back 249 - 518 0 None None Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 9BYJA 1.8 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa VSE Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 3VRYA 2.481 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa B43 Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 3VRYB 2.481 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa B43 Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 3VS3A 2.17 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa VSE Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 3VS3B 2.17 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_niiai APEdist_aaaa VSE Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 3VS4A 2.747 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa VSF Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 3VS4B 2.747 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa VSF Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 3VS6A 2.373 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa VSH Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 3VS6B 2.373 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa VSH Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 4LUEA 3.04 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nnnai APEdist_aaaa VSE Type1.5_Back 81 - 525 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 4LUEB 3.04 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nnnai APEdist_aaaa VSE Type1.5_Back 81 - 525 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 5H09A 1.945 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa OOO Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 5H0BA 1.651 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa OOQ Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 5H0EA 2.1 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa OOS Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 5H0HA 1.72 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa OOV Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 2C0IB 2.3 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nnnai APEdist_aaaa L1G Type1 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 2C0OB 2.85 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nnnai APEdist_aaaa L2G Type1 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 2C0IA 2.3 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nnnai APEdist_aaaa L1G Type1.5_Front 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 2C0OA 2.85 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nnnai APEdist_aaaa L2G Type1.5_Front 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 2C0TA 2.15 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nnnai APEdist_aaaa L3G Type1.5_Front 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 2C0TB 2.15 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nnnai APEdist_aaaa L3G Type1.5_Front 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 3VRZA 2.218 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nnnai APEdist_aaaa VRZ Type1.5_Front 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 3VRZB 2.218 Inactive DFGin‑BLBtrans DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa VRZ Type1.5_Front 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 3VS0A 2.934 Inactive DFGin‑None DFGAsp-rot-out out-out out-none TYR APEdihe_nnnai APEdist_aaaa VS0 Type1 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 3VS0B 2.934 Inactive DFGin‑None DFGAsp-rot-out out-out out-none TYR APEdihe_nnnai APEdist_aaaa VS0 Type1 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 3VS1B 2.464 Inactive DFGin‑None DFGAsp-rot-out out-out out-none TYR APEdihe_nnnai APEdist_aaaa VSA Type1 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 3VS2B 2.609 Inactive DFGin‑None DFGAsp-rot-out out-out out-none TYR APEdihe_nnnai APEdist_aaaa VSB Type1 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 3VS7A 3.001 Inactive DFGin‑None DFGAsp-rot-out out-out out-none TYR APEdihe_nnnai APEdist_aaaa KS1 Type1 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 3VS1A 2.464 Inactive DFGin‑None DFGAsp-rot-out out-out out-none TYR APEdihe_nnnai APEdist_aaaa VSA Type1.5_Back 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR IGF1R IGF1R_HUMAN 1K3AA 2.1 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out in-in TYR APEdihe_iiiai APEdist_aaaa ACP ATPlike 988 - 1286 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 2ZM3A 2.5 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out in-out TYR APEdihe_oiiai APEdist_aaaa 575 Type1 981 - 1285 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 2ZM3B 2.5 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out in-out TYR APEdihe_oiiai APEdist_aaaa 575 Type1 981 - 1285 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 2ZM3C 2.5 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out in-out TYR APEdihe_oiiai APEdist_aaaa 575 Type1 981 - 1285 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 2ZM3D 2.5 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out in-out TYR APEdihe_oiiai APEdist_aaaa 575 Type1 981 - 1285 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3LVPA 3.0 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out in-in TYR APEdihe_iiiai APEdist_aaaa PDR Type1 989 - 1286 0 None None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3LVPB 3.0 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out in-in TYR APEdihe_iiiai APEdist_aaaa PDR Type1 986 - 1285 0 None None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3LVPC 3.0 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out in-out TYR APEdihe_oiiai APEdist_aaaa PDR Type1 987 - 1286 0 None None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3F5PA 2.9 Inactive DFGin‑ABAminus DFGAsp-rot-in out-out in-out TYR APEdihe_oiiai APEdist_aaaa 741 Type1.5_Front 981 - 1286 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3F5PB 2.9 Inactive DFGin‑ABAminus DFGAsp-rot-in out-out in-out TYR APEdihe_oiiai APEdist_aaaa 741 Type1.5_Front 981 - 1286 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3F5PC 2.9 Inactive DFGin‑ABAminus DFGAsp-rot-in out-out in-out TYR APEdihe_oiiai APEdist_aaaa 741 Type1.5_Front 981 - 1286 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3F5PD 2.9 Inactive DFGin‑ABAminus DFGAsp-rot-in out-out in-out TYR APEdihe_oiiai APEdist_aaaa 741 Type1.5_Front 981 - 1286 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3F5PE 2.9 Inactive DFGin‑ABAminus DFGAsp-rot-in out-out in-out TYR APEdihe_oiiai APEdist_aaaa 741 Type1.5_Front 981 - 1285 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3F5PF 2.9 Inactive DFGin‑ABAminus DFGAsp-rot-in out-out in-out TYR APEdihe_oiiai APEdist_aaaa 741 Type1.5_Front 981 - 1285 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3F5PG 2.9 Inactive DFGin‑ABAminus DFGAsp-rot-in out-out in-out TYR APEdihe_oiiai APEdist_aaaa 741 Type1.5_Front 981 - 1285 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3F5PH 2.9 Inactive DFGin‑ABAminus DFGAsp-rot-in out-out in-out TYR APEdihe_oiiai APEdist_aaaa 741 Type1.5_Front 981 - 1286 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3F5PI 2.9 Inactive DFGin‑ABAminus DFGAsp-rot-in out-out in-out TYR APEdihe_oiiai APEdist_aaaa 741 Type1.5_Front 981 - 1285 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3F5PJ 2.9 Inactive DFGin‑ABAminus DFGAsp-rot-in out-out in-out TYR APEdihe_oiiai APEdist_aaaa 741 Type1.5_Front 981 - 1285 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3F5PK 2.9 Inactive DFGin‑ABAminus DFGAsp-rot-in out-out in-out TYR APEdihe_oiiai APEdist_aaaa 741 Type1.5_Front 981 - 1285 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3F5PL 2.9 Inactive DFGin‑ABAminus DFGAsp-rot-in out-out in-out TYR APEdihe_oiiai APEdist_aaaa 741 Type1.5_Front 981 - 1285 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3F5PM 2.9 Inactive DFGin‑ABAminus DFGAsp-rot-in out-out in-out TYR APEdihe_oiiai APEdist_aaaa 741 Type1.5_Front 981 - 1285 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3F5PR 2.9 Inactive DFGin‑ABAminus DFGAsp-rot-in out-out in-out TYR APEdihe_oiiai APEdist_aaaa 741 Type1.5_Front 981 - 1285 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3F5PS 2.9 Inactive DFGin‑ABAminus DFGAsp-rot-in out-out in-out TYR APEdihe_oiiai APEdist_aaaa 741 Type1.5_Front 981 - 1286 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3F5PT 2.9 Inactive DFGin‑ABAminus DFGAsp-rot-in out-out in-out TYR APEdihe_oiiai APEdist_aaaa 741 Type1.5_Front 981 - 1286 0 PTR1161,PTR1165,PTR1166 None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN AF-P08069-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 991 - 1276 0 None None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN AF-P08069-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 991 - 1276 0 None None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3QQUC 2.9 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 01P Type1 989 - 1285 0 None None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3LVPD 3.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa PDR Type1 986 - 1285 0 None None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3QQUA 2.9 Inactive DFGin‑BLBminus DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa 01P Type1 991 - 1285 0 None None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 1JQHA 2.1 Inactive DFGin‑None DFGAsp-rot-out in-out none-in TYR APEdihe_iiiai APEdist_aaaa ANP ATPlike 984 - 1286 0 None E979G,Y980S Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 1JQHB 2.1 Inactive DFGin‑None DFGAsp-rot-out in-out none-in TYR APEdihe_iiiai APEdist_aaaa ANP ATPlike 984 - 1286 0 None E979G,Y980S Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 1JQHC 2.1 Inactive DFGin‑None DFGAsp-rot-out in-out none-in TYR APEdihe_iiiai APEdist_aaaa ANP ATPlike 984 - 1286 0 None E979G,Y980S Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3QQUB 2.9 Inactive DFGin‑None DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa 01P Type1 988 - 1286 0 None None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3QQUD 2.9 Inactive DFGin‑None DFGAsp-rot-in in-out out-out TYR APEdihe_oiiai APEdist_aaaa 01P Type1 989 - 1285 0 None None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 4D2RA 2.1 Inactive DFGin‑None DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa DYK Type1 985 - 1286 0 None None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3NW5A 2.14 Inactive DFGin‑None DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa LGX Type1 985 - 1286 0 None None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3NW6A 2.2 Inactive DFGin‑None DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa LGW Type1 986 - 1286 0 None None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3NW7A 2.11 Inactive DFGin‑None DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa LGV Type1 987 - 1286 0 None None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 5FXQA 2.3 Inactive DFGin‑None DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa GD5 Type1 980 - 1286 0 None None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 5FXRA 2.4 Inactive DFGin‑None DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa 8LN Type1 980 - 1283 0 None None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3I81A 2.08 Inactive DFGin‑None DFGAsp-rot-in out-out out-none TYR APEdihe_niiai APEdist_aaaa EBI Type1 985 - 1286 0 None None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 5FXSA 1.9 Inactive DFGin‑None DFGAsp-rot-in out-none out-in TYR APEdihe_iiiai APEdist_aaaa OZN Type1 980 - 1286 0 None None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3D94A 2.3 Inactive DFGin‑None DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa D94 Type1.5_Front 986 - 1285 0 None None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 8PYIAAA 3.06 Inactive DFGin‑None DFGAsp-rot-in out-out out-none TYR APEdihe_niiai APEdist_aaaa IER Type1.5_Front 986 - 1286 0 None None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 8PYIBBB 3.06 Inactive DFGin‑None DFGAsp-rot-in out-out out-none TYR APEdihe_niiai APEdist_aaaa IER Type1.5_Front 986 - 1285 0 None None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 8PYICCC 3.06 Inactive DFGin‑None DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa IER Type1.5_Front 987 - 1285 0 None None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 8PYIDDD 3.06 Inactive DFGin‑None DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa IER Type1.5_Front 987 - 1285 0 None None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 8PYIEEE 3.06 Inactive DFGin‑None DFGAsp-rot-in out-out out-none TYR APEdihe_niiai APEdist_aaaa IER Type1.5_Front 987 - 1285 0 None None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 8PYIFFF 3.06 Inactive DFGin‑None DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa IER Type1.5_Front 987 - 1285 0 None None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 8PYIGGG 3.06 Inactive DFGin‑None DFGAsp-rot-in out-out out-none TYR APEdihe_niiai APEdist_aaaa IER Type1.5_Front 987 - 1285 0 None None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 8PYIHHH 3.06 Inactive DFGin‑None DFGAsp-rot-in out-out out-none TYR APEdihe_niiai APEdist_aaaa IER Type1.5_Front 987 - 1285 0 None None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 5HZNA 2.2 Inactive DFGin‑None DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa 66A Type1.5_Front 983 - 1286 0 None E1097A,E1099A Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 5HZNB 2.2 Inactive DFGin‑None DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa 66A Type1.5_Front 983 - 1286 0 None E1097A,E1099A Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 5HZNC 2.2 Inactive DFGin‑None DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa 66A Type1.5_Front 983 - 1286 0 None E1097A,E1099A Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 5HZND 2.2 Inactive DFGin‑None DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa 66A Type1.5_Front 983 - 1286 0 None E1097A,E1099A Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 5HZNE 2.2 Inactive DFGin‑None DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa 66A Type1.5_Front 983 - 1286 0 None E1097A,E1099A Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 5HZNF 2.2 Inactive DFGin‑None DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa 66A Type1.5_Front 983 - 1286 0 None E1097A,E1099A Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 5HZNG 2.2 Inactive DFGin‑None DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa 66A Type1.5_Front 983 - 1286 0 None E1097A,E1099A Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 5HZNH 2.2 Inactive DFGin‑None DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa 66A Type1.5_Front 983 - 1285 0 None E1097A,E1099A Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 1M7NA 2.7 Inactive DFGinter‑None DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 982 - 1286 0 None None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 1M7NB 2.7 Inactive DFGinter‑None DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 982 - 1286 0 None None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 1P4OA 1.5 Inactive DFGinter‑None DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 978 - 1285 0 None E1097A,E1099A Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 1P4OB 1.5 Inactive DFGinter‑None DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 977 - 1290 0 None E1097A,E1099A Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3LW0A 1.79 Inactive DFGout‑BBAminus DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa CCX, CCX Type3, Allosteric 983 - 1286 0 None E1097A,E1099A Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3LW0B 1.79 Inactive DFGout‑BBAminus DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa CCX, CCX Type3, Allosteric 983 - 1286 0 None E1097A,E1099A Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3LW0C 1.79 Inactive DFGout‑BBAminus DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa CCX, CCX Type3, Allosteric 983 - 1286 0 None E1097A,E1099A Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3O23A 2.1 Inactive DFGout‑None DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa MQY Type2 991 - 1283 0 None Y987F Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 8PYJAAA 2.702 Inactive DFGout‑None DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa IEA Type2 986 - 1270 0 None None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 8PYKAAA 2.23 Inactive DFGout‑None DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa IC2 Type2 986 - 1270 0 None None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 8PYLAAA 2.93 Inactive DFGout‑None DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa IE0 Type2 986 - 1270 0 None None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 8PYMAAA 2.652 Inactive DFGout‑None DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa IED Type2 984 - 1270 0 None None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 8PYNAAA 1.71 Inactive DFGout‑None DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa ICV Type2 986 - 1270 0 None None Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3LW0D 1.79 Inactive DFGout‑None DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa CCX, CCX Type3, Allosteric 983 - 1286 0 None E1097A,E1099A Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 2OJ9A 2.0 Inactive None‑None DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa BMI Type1 984 - 1286 0 None None Insulin-like growth factor 1 receptor
TYR INSR INSR_HUMAN 2AUHA 3.2 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 1011 - 1310 0 PTR1185,PTR1189,PTR1190 C1008S Insulin receptor
TYR INSR INSR_HUMAN 2B4SB 2.3 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 1014 - 1310 0 PTR1185,PTR1189,PTR1190 C1008S Insulin receptor
TYR INSR INSR_HUMAN 2B4SD 2.3 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 1014 - 1310 0 PTR1185,PTR1189,PTR1190 C1008S Insulin receptor
TYR INSR INSR_HUMAN 3BU6A 1.95 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 1014 - 1310 0 PTR1185,PTR1189,PTR1190 C1008S Insulin receptor
TYR INSR INSR_HUMAN 1IR3A 1.9 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-in TYR APEdihe_iiiai APEdist_aaaa ANP ATPlike 1008 - 1310 0 PTR1185,PTR1189,PTR1190 C1008S,Y1011F Insulin receptor
TYR INSR INSR_HUMAN 3BU5A 2.1 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa ATP ATPlike 1014 - 1310 0 PTR1185,PTR1189,PTR1190 C1008S Insulin receptor
TYR INSR INSR_HUMAN 4XLVA 2.3 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa ACP ATPlike 1001 - 1310 0 PTR999,PTR1185,PTR1189,PTR1190 Y992F,C1008S Insulin receptor
TYR INSR INSR_HUMAN AF-P06213-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 1015 - 1300 0 None None Insulin receptor
TYR INSR INSR_HUMAN AF-P06213-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 1015 - 1300 0 None None Insulin receptor
TYR INSR INSR_HUMAN 1GAGA 2.7 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 1008 - 1310 0 PTR1185,PTR1189,PTR1190 C1008S,Y1011F Insulin receptor
TYR INSR INSR_HUMAN 1RQQA 2.6 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 1014 - 1310 0 PTR1185,PTR1189,PTR1190 C1008S Insulin receptor
TYR INSR INSR_HUMAN 1RQQB 2.6 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 1014 - 1310 0 PTR1185,PTR1189,PTR1190 C1008S Insulin receptor
TYR INSR INSR_HUMAN 3BU3A 1.65 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 1014 - 1310 0 PTR1185,PTR1189,PTR1190 C1008S Insulin receptor
TYR INSR INSR_HUMAN 2Z8CA 3.25 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-in TYR APEdihe_iiiai APEdist_aaaa S91 Type1 1011 - 1310 0 PTR1185,PTR1189,PTR1190 C1008S,Y1011F Insulin receptor
TYR INSR INSR_HUMAN 1I44A 2.4 Inactive DFGin‑None DFGAsp-rot-out in-out none-out TYR APEdihe_nnoai APEdist_aaaa ACP ATPlike 1013 - 1310 0 None C1008S,Y1011F,D1188A Insulin receptor
TYR INSR INSR_HUMAN 1P14A 1.9 Inactive DFGin‑None DFGAsp-rot-out in-out none-none TYR APEdihe_nnnai APEdist_aaaa No_ligand No_ligand 1005 - 1310 0 None C1008S,D1159N Insulin receptor
TYR INSR INSR_HUMAN 4IBMA 1.8 Inactive DFGin‑None DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa IR1 Type1 1009 - 1309 0 None K1278N Insulin receptor
TYR INSR INSR_HUMAN 4IBMB 1.8 Inactive DFGin‑None DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa IR1 Type1 1014 - 1310 0 None K1278N Insulin receptor
TYR INSR INSR_HUMAN 5E1SA 2.264 Inactive DFGin‑None DFGAsp-rot-out in-out none-none TYR APEdihe_nniai APEdist_aaaa 5JA Type1 1010 - 1310 0 None None Insulin receptor
TYR INSR INSR_HUMAN 3EKKA 2.1 Inactive DFGin‑None DFGAsp-rot-out in-out none-none TYR APEdihe_niiai APEdist_aaaa GS2 Type1 1007 - 1309 0 None C1008S,D1159N Insulin receptor
TYR INSR INSR_HUMAN 3EKNA 2.2 Inactive DFGin‑None DFGAsp-rot-out in-out out-out TYR APEdihe_oiiai APEdist_aaaa GS3 Type1 1011 - 1310 0 None C1008S,D1159N Insulin receptor
TYR INSR INSR_HUMAN 5HHWA 1.79 Inactive DFGin‑None DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa 60O Type1.5_Front 1005 - 1310 0 None C1008S,D1159N Insulin receptor
TYR INSR INSR_HUMAN 1IRKA 2.1 Inactive DFGout‑BBAminus DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 1008 - 1310 0 None None Insulin receptor
TYR INSR INSR_HUMAN 3ETAA 2.6 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 351 Type2 1017 - 1310 0 None None Insulin receptor
TYR INSR INSR_HUMAN 3ETAB 2.6 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 351 Type2 1017 - 1310 0 None None Insulin receptor
TYR INSR INSR_HUMAN 8DWNA 2.15 Inactive None‑None DFGAsp-rot-none in-out none-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 1014 - 1310 0 PTR1185,PTR1189 C1008S,Y1011F Insulin receptor
TYR INSRR INSRR_HUMAN AF-P14616-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 971 - 1256 0 None None Insulin receptor-related protein
TYR INSRR INSRR_HUMAN AF-P14616-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 971 - 1256 0 None None Insulin receptor-related protein
TYR ITK ITK_HUMAN AF-Q08881-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 355 - 620 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN AF-Q08881-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 355 - 620 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 3QGYB 2.1 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa L7O Type1 357 - 616 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 3MIYB 1.67 Inactive DFGin‑BLAplus DFGAsp-rot-out in-out none-none TYR APEdihe_nnnai APEdist_aaaa B49 Type1 357 - 619 0 None C477S,E614A,E617A Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4MF1A 2.113 Inactive DFGin‑BLAplus DFGAsp-rot-out in-out none-none TYR APEdihe_nnnai APEdist_aaaa 29Y Type1 357 - 619 0 None C477S,E614A,E617A Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4MF1B 2.113 Inactive DFGin‑BLAplus DFGAsp-rot-out in-out out-none TYR APEdihe_nniai APEdist_aaaa 29Y Type1 357 - 619 0 None C477S,E614A,E617A Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4RFMA 2.1 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out out-none TYR APEdihe_nniai APEdist_aaaa 3P6 Type1 357 - 618 0 None C477S,E614A,E617A Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4KIOA 2.18 Inactive DFGin‑BLAplus DFGAsp-rot-out out-out none-none TYR APEdihe_nnnai APEdist_aaaa G5K Type1 357 - 619 0 None Y512E Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4KIOB 2.18 Inactive DFGin‑BLAplus DFGAsp-rot-out out-out none-none TYR APEdihe_nnnai APEdist_aaaa G5K Type1 357 - 619 0 None Y512E Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4KIOD 2.18 Inactive DFGin‑BLAplus DFGAsp-rot-out out-out none-none TYR APEdihe_nnnai APEdist_aaaa G6K Type1 357 - 618 0 None Y512E Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4L7SA 2.03 Inactive DFGin‑BLAplus DFGAsp-rot-out in-out none-none TYR APEdihe_nnnai APEdist_aaaa G7K Type1 357 - 620 0 None Y512E Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4L7SB 2.03 Inactive DFGin‑BLAplus DFGAsp-rot-out in-out none-none TYR APEdihe_nnnai APEdist_aaaa G7K Type1 357 - 620 0 None Y512E Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4MF0A 2.67 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out none-none TYR APEdihe_nnnai APEdist_aaaa 29Z Type1 357 - 619 0 None Y512E Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4PP9A 2.58 Inactive DFGin‑BLAplus DFGAsp-rot-out in-out none-none TYR APEdihe_nnnai APEdist_aaaa 2VT Type1 357 - 619 0 None Y512E Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4PP9B 2.58 Inactive DFGin‑BLAplus DFGAsp-rot-out in-out none-none TYR APEdihe_nnnai APEdist_aaaa 2VT Type1 357 - 619 0 None Y512E Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4QD6A 2.45 Inactive DFGin‑BLAplus DFGAsp-rot-out out-out none-none TYR APEdihe_nnnai APEdist_aaaa 30T Type1 357 - 619 0 None Y512E Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 3QGWA 2.1 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out none-none TYR APEdihe_nniai APEdist_aaaa PQC Type1 358 - 618 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 3QGYA 2.1 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out none-none TYR APEdihe_nnnai APEdist_aaaa PQC Type1 357 - 618 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 3V5JA 2.59 Inactive DFGin‑BLAplus DFGAsp-rot-out out-none none-none TYR APEdihe_nnnai APEdist_aaaa 0F2 Type1 357 - 618 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 3V5LA 1.86 Inactive DFGin‑BLAplus DFGAsp-rot-out out-none none-none TYR APEdihe_nnnai APEdist_aaaa 0G1 Type1 357 - 616 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 3V5LB 1.86 Inactive DFGin‑BLAplus DFGAsp-rot-out out-out none-none TYR APEdihe_nnnai APEdist_aaaa 0G1 Type1 357 - 619 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 3V5LC 1.86 Inactive DFGin‑BLAplus DFGAsp-rot-out in-out none-out TYR APEdihe_nnoai APEdist_aaaa 0G1 Type1 357 - 616 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 3V5LD 1.86 Inactive DFGin‑BLAplus DFGAsp-rot-out out-out none-out TYR APEdihe_nnoai APEdist_aaaa 0G1 Type1 357 - 619 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 3V8TA 2.0 Inactive DFGin‑BLAplus DFGAsp-rot-out out-out none-none TYR APEdihe_nnnai APEdist_aaaa 477 Type1 357 - 618 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 3V8TB 2.0 Inactive DFGin‑BLAplus DFGAsp-rot-out out-none none-none TYR APEdihe_nnnai APEdist_aaaa 477 Type1 357 - 619 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 3V8WA 2.27 Inactive DFGin‑BLAplus DFGAsp-rot-out out-none none-none TYR APEdihe_nnnai APEdist_aaaa 0G2 Type1 357 - 619 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 3V8WB 2.27 Inactive DFGin‑BLAplus DFGAsp-rot-out out-none none-none TYR APEdihe_nnnai APEdist_aaaa 0G2 Type1 357 - 619 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4KIOC 2.18 Inactive DFGin‑BLAplus DFGAsp-rot-out out-out none-out TYR APEdihe_nnoai APEdist_aaaa G6K, G5K Type1, Type1 357 - 620 0 None Y512E Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 1SNXA 3.2 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nnnai APEdist_aaaa No_ligand No_ligand 357 - 619 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 1SNXB 3.2 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nnnai APEdist_aaaa No_ligand No_ligand 357 - 619 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 3MJ2A 1.9 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa MJG Type1 357 - 615 0 None C477S,E614A,E617A Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4PPAA 2.67 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nnnai APEdist_aaaa 2VU Type1 357 - 619 0 None Y512E Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4PPAB 2.67 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nnnai APEdist_aaaa 2VU Type1 357 - 619 0 None Y512E Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4PPBA 2.82 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nnnai APEdist_aaaa 2VV Type1 357 - 619 0 None Y512E Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4PPBB 2.82 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nnnai APEdist_aaaa 2VV Type1 357 - 619 0 None Y512E Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4QD6B 2.45 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nnnai APEdist_aaaa 30T Type1 357 - 619 0 None Y512E Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 1SM2A 2.3 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nnnai APEdist_aaaa STU Type1 357 - 619 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 1SNUA 2.5 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nnnai APEdist_aaaa STU Type1 357 - 619 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4HCTA 1.48 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 18R Type1 354 - 618 0 None K596R Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4HCUA 1.43 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 13L Type1 356 - 618 0 None K596R Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4HCVA 1.48 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 13J Type1 356 - 618 0 None K596R Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 9NWXA 1.348 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa A1B66 Type1 355 - 618 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 3T9TA 1.65 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa IAQ Type1 356 - 618 0 None F435T,K596R Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4M0YA 1.7 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa M0Y, M0Y Type1, Type3 356 - 618 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4M14A 1.55 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa QWS, QWS Type1, Type3 355 - 617 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4M12A 2.15 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 1YZ Type3 355 - 618 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4M13A 1.85 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 1E0 Type3 355 - 618 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4M15A 1.52 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa QWS, ADP Type3, ATPlike 355 - 617 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4M0ZA 2.0 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa M0Z, M0Z Type3, Type1 355 - 618 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 3MIYA 1.67 Inactive DFGin‑None DFGAsp-rot-out in-out none-none TYR APEdihe_nnnai APEdist_aaaa B49 Type1 357 - 619 0 None C477S,E614A,E617A Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 3MJ1A 1.72 Inactive DFGin‑None DFGAsp-rot-out out-out none-none TYR APEdihe_nnnai APEdist_aaaa 614 Type1 357 - 615 0 None C477S,E614A,E617A Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4PQNA 1.71 Inactive DFGin‑None DFGAsp-rot-out in-out none-none TYR APEdihe_nniai APEdist_aaaa 2W6 Type1 357 - 615 0 None C477S,E614A,E617A Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4MF0B 2.67 Inactive DFGin‑None DFGAsp-rot-in out-out none-none TYR APEdihe_nnnai APEdist_aaaa 29Z Type1 357 - 619 0 None Y512E Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4PPCA 2.95 Inactive DFGin‑None DFGAsp-rot-out out-out none-none TYR APEdihe_nnnai APEdist_aaaa 2VW Type1 357 - 619 0 None Y512E Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4PPCB 2.95 Inactive DFGin‑None DFGAsp-rot-out out-out none-none TYR APEdihe_nnnai APEdist_aaaa 2VW Type1 357 - 619 0 None Y512E Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 3QGWB 2.1 Inactive DFGin‑None DFGAsp-rot-out in-out none-none TYR APEdihe_nnnai APEdist_aaaa L7A Type1 358 - 616 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 1SM2B 2.3 Inactive DFGin‑None DFGAsp-rot-in out-out none-none TYR APEdihe_nnnai APEdist_aaaa STU Type1 358 - 617 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 1SNUB 2.5 Inactive DFGin‑None DFGAsp-rot-out out-out none-none TYR APEdihe_nnnai APEdist_aaaa STU Type1 358 - 617 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 3V5JB 2.59 Inactive DFGin‑None DFGAsp-rot-out out-none none-none TYR APEdihe_nnnai APEdist_aaaa 0F2 Type1 357 - 620 0 None None Tyrosine-protein kinase ITK/TSK
TYR JAK1-2 JAK1_HUMAN 5KHWA 2.47 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa ADP ATPlike 867 - 1153 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4E4LE 2.0 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa No_ligand No_ligand 864 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 3EYGA 1.9 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa MI1 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 3EYHA 2.0 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa IZA Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 5E1EB 2.3 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 5JG Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6AAHA 1.83 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 9T6 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6AAHB 1.83 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 9T6 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6TPEA 2.87 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa NTW Type1 864 - 1153 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6TPEB 2.87 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa NTW Type1 864 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6TPFA 2.31 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa NTQ Type1 864 - 1153 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6TPFB 2.31 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa NTQ Type1 865 - 1153 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6GGHA 1.7 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa EYQ Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6GGHB 1.7 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa EYQ Type1 863 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6ELRA 1.8 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa BFK Type1 854 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6ELRB 1.8 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa BFK Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6SM8B 1.85 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa LKT Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6SMBA 2.04 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa LKQ Type1 863 - 1153 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6SMBB 2.04 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa LKQ Type1 863 - 1153 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4E4LA 2.0 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 0NH Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4E4LB 2.0 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 0NH Type1 864 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4E4LD 2.0 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 0NH Type1 864 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4E4NA 1.9 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 0NL Type1 854 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4E4NB 1.9 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 0NL Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4E5WA 1.86 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 0NT Type1 854 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4E5WB 1.86 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 0NT Type1 865 - 1153 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4EHZA 2.174 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa JAK Type1 858 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4EHZB 2.174 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa JAK Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4EHZC 2.174 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa JAK Type1 866 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4EHZD 2.174 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa JAK Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4EI4A 2.22 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 0Q2 Type1 854 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4EI4B 2.22 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 0Q2 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4FK6A 2.2 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 0UJ Type1 863 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4FK6B 2.2 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 0UJ Type1 864 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4I5CA 2.1 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa C5I Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4I5CB 2.1 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa C5I Type1 854 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4IVBA 1.9 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 1J5 Type1 854 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4IVBB 1.9 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 1J5 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4IVCA 2.35 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 1J6 Type1 854 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4IVCB 2.35 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 1J6 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4IVDA 1.93 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 15T Type1 854 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4IVDB 1.93 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 15T Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4K6ZA 2.73 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 1Q3 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4K77A 2.4 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 1Q4 Type1 864 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4K77B 2.4 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 1Q4 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 5HX8A 2.2 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 66P Type1 855 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 5HX8B 2.2 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 66P Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 5WO4A 1.84 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa B7V Type1 854 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 5WO4B 1.84 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa B7V Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6HZUA 2.2 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa GYQ Type1 854 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6HZUB 2.2 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa GYQ Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6N77A 1.64 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa KEJ Type1 866 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6N77B 1.64 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa KEJ Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6N78A 1.83 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa KEP Type1 866 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6N79A 2.27 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa KES Type1 866 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6N7BA 1.81 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa KEY Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6N7CA 1.69 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa KF1 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6N7CB 1.69 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa KF1 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6N7DA 1.78 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa KF4 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6RSBA 1.8 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa KGZ Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6RSBB 1.8 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa KGZ Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6RSCA 1.85 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa KH5 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6RSCB 1.85 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa KH5 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6RSDA 1.76 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa KH8 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6RSDB 1.76 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa KH8 Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6RSEA 1.8 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa KHH Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6RSEB 1.8 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa KHH Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6RSHA 1.71 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa KHE Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6RSHB 1.71 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa KHE Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6SM8A 1.85 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa LKT Type1 854 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 8S85A 1.75 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa A1H5R Type1 854 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 8S85B 1.75 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa A1H5R Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6N7AA 1.33 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa KEV Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6N7AB 1.33 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa KEV Type1 854 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 5KHXA 2.4 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 6TE Type1 867 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6BBUA 2.08 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa D7D Type1 867 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6DBNA 2.48 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa G4J Type1 867 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6W8LA 2.11 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa R4S Type1 867 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6C7YA 2.499 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa ADP ATPlike 869 - 1153 0 PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 5KHWB 2.47 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa ADP ATPlike 867 - 1153 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN AF-P23458-K2A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 867 - 1154 0 None None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN AF-P23458-K4A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 867 - 1154 0 None None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 5E1EA 2.3 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 5JG Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-1 JAK1_HUMAN 4L01A 1.9 Pseudo DFGin‑None DFGAsp-rot-out in-na out-out TYR APEdihe_oooao APEdist_aaaa No_ligand No_ligand 565 - 850 0 None V658F Tyrosine-protein kinase JAK1
TYR JAK1-1 JAK1_HUMAN 4L01B 1.9 Pseudo DFGin‑None DFGAsp-rot-out in-na out-out TYR APEdihe_oooao APEdist_aaaa No_ligand No_ligand 565 - 849 0 None V658F Tyrosine-protein kinase JAK1
TYR JAK1-1 JAK1_HUMAN 4L00A 1.8 Pseudo DFGin‑None DFGAsp-rot-out in-na out-out TYR APEdihe_oooao APEdist_aaaa No_ligand No_ligand 564 - 850 0 None None Tyrosine-protein kinase JAK1
TYR JAK1-1 JAK1_HUMAN 4L00B 1.8 Pseudo DFGin‑None DFGAsp-rot-out in-na out-out TYR APEdihe_oooao APEdist_aaaa No_ligand No_ligand 565 - 850 0 None None Tyrosine-protein kinase JAK1
TYR JAK2-2 JAK2_HUMAN 5HEZA 2.66 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oioao APEdist_aaaa 1M3, 1M3 Allosteric, Type1 842 - 1132 0 PTR1007,PTR1008 P1057A Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5HEZB 2.66 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oioao APEdist_aaaa 1M3, 1M3 Allosteric, Type1 842 - 1132 0 PTR1007,PTR1008 P1057A Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5HEZD 2.66 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oioao APEdist_aaaa 1M3, 1M3 Allosteric, Type1 842 - 1132 0 PTR1007,PTR1008 P1057A Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 7UYWA 2.51 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa OV0 Type1 842 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6BBVA 1.8 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa D7D Type1 843 - 1131 0 None None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6X8EA 1.75 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa UWP Type1 843 - 1130 0 PTR1007,PTR1008 M1073S,F1076T Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6X8EB 1.75 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa UWP Type1 843 - 1132 0 PTR1007,PTR1008 M1073S,F1076T Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 7LL5A 1.5 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa Y5G Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 2B7AA 2.0 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa IZA Type1 843 - 1132 0 PTR1007,PTR1008 N1129Q Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 2B7AB 2.0 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa IZA Type1 840 - 1132 0 PTR1007,PTR1008 N1129Q Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3FUPA 2.4 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa MI1 Type1 843 - 1132 0 PTR1007,PTR1008 N1129Q Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3FUPB 2.4 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa MI1 Type1 840 - 1132 0 PTR1007,PTR1008 N1129Q Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4P7EA 2.4 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 2HB Type1 843 - 1132 0 PTR1007,PTR1008 N1129Q Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4P7EB 2.4 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 2HB Type1 840 - 1132 0 PTR1007,PTR1008 N1129Q Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3E62A 1.922 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 5B1 Type1 839 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3E63A 1.9 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 5B2 Type1 840 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3E64A 1.8 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 5B3 Type1 839 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3KRRA 1.8 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa DQX Type1 840 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3LPBA 2.0 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa NVB Type1 842 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3LPBB 2.0 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa NVB Type1 840 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5TQ6A 2.06 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa 7GV Type1 843 - 1132 0 PTR1007,PTR1008 M1073S,F1076T Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5TQ6B 2.06 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 7GV Type1 843 - 1130 0 PTR1007,PTR1008 M1073S,F1076T Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5TQ7A 2.1 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa 7GT Type1 841 - 1132 0 PTR1007,PTR1008 M1073S,F1076T,I1126V Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5TQ7B 2.1 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 7GT Type1 843 - 1132 0 PTR1007,PTR1008 M1073S,F1076T,I1126V Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 7LL4A 1.31 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa Y5D Type1 839 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 7REEA 1.38 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 4LY Type1 839 - 1130 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4D0WA 1.77 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa VVQ Type1 839 - 1130 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4D0XA 1.82 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 953 Type1 839 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5AEPA 1.95 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa QUP Type1 840 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3TJCA 2.4 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 0TP Type1 843 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3TJCB 2.4 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 0TP Type1 840 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3TJDA 2.9 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 6TP Type1 843 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3TJDB 2.9 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 6TP Type1 840 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4HGEA 2.3 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 15V Type1 843 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4HGEB 2.3 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 15V Type1 839 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4IVAA 1.5 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 1J5 Type1 841 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4JI9A 2.4 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 1M3 Type1 843 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4JI9B 2.4 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 1M3 Type1 839 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3Q32A 2.5 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa J2I Type1 840 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3Q32B 2.5 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_ooiai APEdist_aaaa J2I Type1 839 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5CF8A 1.8 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 50V Type1 842 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5CF8B 1.8 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 50V Type1 839 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4AQCA 1.9 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 88A Type1 842 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4AQCB 1.9 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 88A Type1 836 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4F08A 2.82 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 1RS Type1 843 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4F08B 2.82 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 1RS Type1 843 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4F09A 2.4 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa JAK Type1 843 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4GFMA 2.3 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 0X2 Type1 840 - 1130 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3RVGA 2.498 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 17P Type1 841 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VGLA 1.9 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa RXT Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VGLB 1.9 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa RXT Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VGLC 1.9 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa RXT Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VGLD 1.9 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa RXT Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VN8A 1.9 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 3JW Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VN8B 1.9 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 3JW Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNBA 2.19 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa R6P Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNBB 2.19 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa R6P Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNCA 2.3 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa R6V Type1 840 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNCB 2.3 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa R6V Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNEA 2.32 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 2TA Type1 840 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNEB 2.32 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 2TA Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNFA 2.06 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa R6S Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNFB 2.06 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa R6S Type1 841 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNGA 2.5 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa R6M Type1 841 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNGB 2.5 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_ioiai APEdist_aaaa R6M Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNHA 2.4 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa XZS Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNHB 2.4 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa XZS Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNIA 2.1 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa R61 Type1 842 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNIB 2.1 Inactive DFGin‑ABAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa R61 Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNJA 1.9 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa R5S Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNJB 1.9 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa R5S Type1 842 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNKA 2.0 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa RXT Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNKB 2.0 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa RXT Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNKC 2.0 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa RXT Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNKD 2.0 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa RXT Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNLA 2.4 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 5W2 Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNLB 2.4 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 5W2 Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNLC 2.4 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 5W2 Type1 842 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNLD 2.4 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 5W2 Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNMA 2.2 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa R5Y Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNMB 2.2 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa R5Y Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VS3A 2.0 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa R6V Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VS3B 2.0 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa R6V Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VSNA 2.5 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa RG4 Type1 840 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VSNB 2.5 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa RG4 Type1 842 - 1132 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VSNC 2.5 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa RG4 Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VSND 2.5 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa RG4 Type1 843 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6WTNA 1.83 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa RXT Type1 843 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6WTOA 1.74 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 3JW Type1 843 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6WTPA 2.5 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa U8P Type1 844 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6WTQA 1.8 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa U8J Type1 849 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 8G6ZA 2.45 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa YSI Type1 843 - 1131 0 PTR1007 M1073S,F1076T Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 8G6ZB 2.45 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa YSI Type1 843 - 1131 0 PTR1007 M1073S,F1076T Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 8G8OA 2.2 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa YT0 Type1 842 - 1130 0 PTR1007,PTR1008 M1073S,F1076T Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 8G8OB 2.2 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa YT0 Type1 843 - 1130 0 PTR1007,PTR1008 M1073S,F1076T Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 8G8XA 1.97 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa YT8 Type1 842 - 1130 0 PTR1007,PTR1008 M1073S,F1076T Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 8G8XB 1.97 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa YT8 Type1 842 - 1130 0 PTR1007,PTR1008 M1073S,F1076T Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3IO7A 2.6 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 1P5 Type1 842 - 1130 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3IOKA 2.1 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 1P6 Type1 842 - 1130 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 8BX9A 1.4 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa S59 Type1 840 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 8BX9B 1.4 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa S59 Type1 840 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 8BXCA 1.9 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa S4R Type1 840 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 8BXCB 1.9 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa S4R Type1 840 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 8BXHA 1.3 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa C87 Type1 840 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 8BPVA 1.7 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 6T3 Type1 840 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 8BPWA 1.8 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 2V9 Type1 840 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 8BPWB 1.8 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 2V9 Type1 840 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4ZIMA 2.65 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 4OK Type1 842 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4ZIMB 2.65 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 4OK Type1 839 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5CF4A 2.38 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 50Y Type1 843 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5CF4B 2.38 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 50Y Type1 839 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5CF5A 2.45 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 50W Type1 842 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5CF5B 2.45 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 50W Type1 839 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5CF6A 2.5 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 50O Type1 842 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5CF6B 2.5 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 50O Type1 839 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4E6DA 2.22 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 0NU Type1 840 - 1132 0 PTR1007,PTR1008 Q853R,Y931F,D939E Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4E6DB 2.22 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 0NU Type1 840 - 1132 0 PTR1007,PTR1008 Q853R,Y931F,D939E Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4E6QA 1.948 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 0NV Type1 835 - 1132 0 PTR1007,PTR1008 Q853R,Y931F,D939E Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4E6QB 1.948 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 0NV Type1 835 - 1132 0 PTR1007,PTR1008 Q853R,Y931F,D939E Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 2XA4A 2.04 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa AZ5 Type1 843 - 1130 0 PTR1007,PTR1008 K943A,K945A Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 2XA4B 2.04 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa AZ5 Type1 843 - 1131 0 PTR1007,PTR1008 K943A,K945A Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3ZMMA 2.51 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa F9J Type1 844 - 1130 0 PTR1007,PTR1008 K943A,K945A Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3ZMMB 2.51 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa F9J Type1 843 - 1131 0 PTR1007,PTR1008 K943A,K945A Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4C61A 2.45 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa LMM Type1 844 - 1130 0 PTR1007,PTR1008 K943A,K945A Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4C61B 2.45 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa LMM Type1 843 - 1131 0 PTR1007,PTR1008 K943A,K945A Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4C62A 2.75 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa XWW Type1 844 - 1130 0 PTR1007,PTR1008 K943A,K945A Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4C62B 2.75 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa XWW Type1 843 - 1131 0 PTR1007,PTR1008 K943A,K945A Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5HEZC 2.66 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oioao APEdist_aaaa 1M3, 1M3 Type1, Allosteric 842 - 1132 0 PTR1007,PTR1008 P1057A Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN AF-O60674-K2A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 841 - 1132 0 None None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN AF-O60674-K4A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 841 - 1132 0 None None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 2W1IB 2.6 Inactive DFGin‑BLAminus DFGAsp-rot-out in-out in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 843 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4YTCA 2.16 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 4HW Type1 842 - 1130 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4YTFA 1.78 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 4HZ Type1 842 - 1130 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4YTHA 2.04 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 467 Type1 842 - 1130 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4YTIA 2.52 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa VJK Type1 842 - 1130 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4D1SA 1.66 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa BJG Type1 842 - 1130 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4JIAA 1.85 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 1K3 Type1 833 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4E4MA 2.25 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 0NH Type1 835 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4E4MB 2.25 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 0NH Type1 835 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4E4MD 2.25 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 0NH Type1 835 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4E4ME 2.25 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 0NH Type1 835 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4GMYA 2.403 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 0X5 Type1 833 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 8BX6A 1.5 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa S5I Type1 840 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5USYA 2.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa SKE Type1 840 - 1130 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5USYB 2.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa SKE Type1 840 - 1130 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6DRWA 2.303 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-none TYR APEdihe_nniai APEdist_aaaa SKE Type1 840 - 1131 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 8BM2A 1.5 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa QQC Type1 840 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 8BM2B 1.5 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa QQC Type1 840 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5WEVA 1.854 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 9ZS Type1 833 - 1130 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 2W1IA 2.6 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa L0I Type1 843 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6TPDA 1.99 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa QZ8 Type1 842 - 1130 0 None None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5L3AA 1.98 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 6DP Type1 841 - 1130 0 None Y1007F,Y1008F Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6AAJA 2.37 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 9T6 Type1 843 - 1130 0 PTR1007,PTR1008 K943A,K945A Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6AAJB 2.37 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 9T6 Type1 843 - 1131 0 PTR1007,PTR1008 K943A,K945A Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4BBEA 1.9 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 3O4 Type1 841 - 1128 0 None D976N Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4BBEB 1.9 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 3O4 Type1 841 - 1128 0 None D976N Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4BBEC 1.9 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 3O4 Type1 841 - 1128 0 None D976N Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4BBED 1.9 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 3O4 Type1 841 - 1128 0 None D976N Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4BBFA 2.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa O19 Type1 841 - 1128 0 None D976N Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4BBFB 2.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa O19 Type1 841 - 1128 0 None D976N Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4BBFC 2.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa O19 Type1 841 - 1128 0 None D976N Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4BBFD 2.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa O19 Type1 841 - 1128 0 None D976N Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5TQ4A 2.3 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 7GY Type1.5_Back 841 - 1132 0 PTR1007,PTR1008 M1073S,F1076T Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5TQ5A 2.3 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 7GX Type1.5_Back 841 - 1131 0 None M1073S,F1076T Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5TQ8A 1.59 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 7GS Type1.5_Back 841 - 1131 0 None M1073S,F1076T Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 7Q7IA 1.78 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 9I8 Type1.5_Back 840 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 7Q7KA 1.61 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 9I5 Type1.5_Back 840 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 7Q7LA 1.97 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 9I2 Type1.5_Back 843 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 7Q7WA 1.85 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 9HR Type1.5_Back 840 - 1131 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3JY9A 2.1 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa JZH Type1.5_Back 842 - 1130 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3KCKA 2.2 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 3KC Type1.5_Back 842 - 1130 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 5I4NA 1.54 Pseudo DFGin‑None DFGAsp-rot-out out-na out-out TYR APEdihe_oooao APEdist_aaaa ATP ATPlike 537 - 809 0 None E596A,V617F,W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 4FVRA 2.0 Pseudo DFGin‑None DFGAsp-rot-out out-na out-out TYR APEdihe_oooao APEdist_aaaa ATP ATPlike 536 - 809 0 None V617F,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 4FVQA 1.75 Pseudo DFGin‑None DFGAsp-rot-out out-na out-out TYR APEdihe_oooao APEdist_aaaa ATP ATPlike 536 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8C08A 2.2 Pseudo DFGin‑None DFGAsp-rot-out in-na out-out TYR APEdihe_oooao APEdist_aaaa ATP ATPlike 537 - 810 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8C08B 2.2 Pseudo DFGin‑None DFGAsp-rot-out out-na out-out TYR APEdihe_oooao APEdist_aaaa ATP ATPlike 536 - 810 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8BA4B 2.1 Pseudo DFGin‑None DFGAsp-rot-out out-na out-out TYR APEdihe_oooao APEdist_aaaa No_ligand No_ligand 536 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 4FVPA 2.01 Pseudo DFGin‑None DFGAsp-rot-out out-na out-out TYR APEdihe_oooao APEdist_aaaa No_ligand No_ligand 536 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8C09A 1.9 Pseudo DFGin‑None DFGAsp-rot-out out-na out-out TYR APEdihe_oooao APEdist_aaaa No_ligand No_ligand 538 - 809 0 None I559F,W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 6G3CA 1.6 Pseudo DFGin‑None DFGAsp-rot-out in-na out-out TYR APEdihe_oooao APEdist_aaaa EKT Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 6G3CB 1.6 Pseudo DFGin‑None DFGAsp-rot-out in-na out-out TYR APEdihe_oooao APEdist_aaaa EKT Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 6D2IA 3.192 Pseudo DFGin‑None DFGAsp-rot-out in-na out-out TYR APEdihe_oooao APEdist_aaaa 35R Type1 536 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 6D2IB 3.192 Pseudo DFGin‑None DFGAsp-rot-out in-na out-out TYR APEdihe_oooao APEdist_aaaa 35R Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8B8NA 2.0 Pseudo DFGin‑None DFGAsp-rot-out out-na out-out TYR APEdihe_oooao APEdist_aaaa AQG Type1 536 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8B8UA 1.5 Pseudo DFGin‑None DFGAsp-rot-out in-na out-out TYR APEdihe_oooao APEdist_aaaa T7I Type1 536 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8B8UB 1.5 Pseudo DFGin‑None DFGAsp-rot-out in-na out-out TYR APEdihe_oooao APEdist_aaaa T7I Type1 538 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8BA2A 1.5 Pseudo DFGin‑None DFGAsp-rot-out out-na out-out TYR APEdihe_oooao APEdist_aaaa Q9X Type1 536 - 810 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8BA4A 2.1 Pseudo DFGin‑None DFGAsp-rot-out in-na out-out TYR APEdihe_oooao APEdist_aaaa Q8U Type1 536 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 7F7WA 1.83 Pseudo DFGin‑None DFGAsp-rot-out out-na out-out TYR APEdihe_oooao APEdist_aaaa 36H Type1 536 - 810 0 None None Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 7F7WB 1.83 Pseudo DFGin‑None DFGAsp-rot-out out-na out-out TYR APEdihe_oooao APEdist_aaaa 36H Type1 536 - 810 0 None None Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8B99A 1.6 Pseudo DFGin‑None DFGAsp-rot-out out-na out-out TYR APEdihe_oooao APEdist_aaaa SKE Type1 536 - 809 0 None W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8B9EA 1.5 Pseudo DFGin‑None DFGAsp-rot-out out-na out-out TYR APEdihe_oooao APEdist_aaaa Q7F Type1 536 - 809 0 None W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8BABA 1.55 Pseudo DFGin‑None DFGAsp-rot-out out-na out-out TYR APEdihe_oooao APEdist_aaaa Q8N Type1 536 - 809 0 None W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8BAKA 1.65 Pseudo DFGin‑None DFGAsp-rot-out out-na out-out TYR APEdihe_oooao APEdist_aaaa AD5 Type1 536 - 809 0 None W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8C0AA 1.7 Pseudo DFGin‑None DFGAsp-rot-out in-na out-out TYR APEdihe_oooao APEdist_aaaa T7I Type1 536 - 809 0 None W659A,R683S,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8C0AB 1.7 Pseudo DFGin‑None DFGAsp-rot-out in-na out-out TYR APEdihe_oooao APEdist_aaaa T7I Type1 536 - 808 0 None W659A,R683S,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 5WIJA 2.04 Pseudo DFGin‑None DFGAsp-rot-out in-na out-out TYR APEdihe_oooao APEdist_aaaa AQG Type1 536 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 5WIKB 2.6 Pseudo DFGin‑None DFGAsp-rot-out out-na out-out TYR APEdihe_oooao APEdist_aaaa 584 Type1 536 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 5WILA 2.2 Pseudo DFGin‑None DFGAsp-rot-out out-na out-out TYR APEdihe_oooao APEdist_aaaa YDJ Type1 536 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 5WIMA 2.55 Pseudo DFGin‑None DFGAsp-rot-out out-na out-out TYR APEdihe_oooao APEdist_aaaa 35R Type1 536 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 5WINA 2.38 Pseudo DFGin‑None DFGAsp-rot-out out-na out-out TYR APEdihe_oooao APEdist_aaaa SKE Type1 536 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 5USZA 2.103 Pseudo DFGin‑None DFGAsp-rot-out in-na out-out TYR APEdihe_oooao APEdist_aaaa SKE Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 5UT0A 2.102 Pseudo DFGin‑None DFGAsp-rot-out in-na out-out TYR APEdihe_oooao APEdist_aaaa 35R Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 5UT1A 1.95 Pseudo DFGin‑None DFGAsp-rot-out in-na out-out TYR APEdihe_oooao APEdist_aaaa 7DZ Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 5UT2A 1.75 Pseudo DFGin‑None DFGAsp-rot-out in-na out-out TYR APEdihe_oooao APEdist_aaaa 3YT Type1 536 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 5UT3A 1.501 Pseudo DFGin‑None DFGAsp-rot-out in-na out-out TYR APEdihe_oooao APEdist_aaaa IK1 Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 5UT4A 2.0 Pseudo DFGin‑None DFGAsp-rot-out in-na out-out TYR APEdihe_oooao APEdist_aaaa DQX Type1 537 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 5UT5A 1.9 Pseudo DFGin‑None DFGAsp-rot-out in-na out-out TYR APEdihe_oooao APEdist_aaaa 2HB Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 5UT6A 1.645 Pseudo DFGin‑None DFGAsp-rot-out in-na out-out TYR APEdihe_oooao APEdist_aaaa 8MY Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 6BRWA 2.031 Pseudo DFGin‑None DFGAsp-rot-out in-na out-out TYR APEdihe_oooao APEdist_aaaa 5BS Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 6BS0A 1.541 Pseudo DFGin‑None DFGAsp-rot-out in-na out-out TYR APEdihe_oooao APEdist_aaaa E4V Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 6BSSA 2.1 Pseudo DFGin‑None DFGAsp-rot-out in-na out-out TYR APEdihe_oooao APEdist_aaaa 4SP Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 6M9HA 1.79 Pseudo DFGin‑None DFGAsp-rot-out in-na out-out TYR APEdihe_oooao APEdist_aaaa J9D Type1 536 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 6OAVA 1.939 Pseudo DFGin‑None DFGAsp-rot-out in-na out-out TYR APEdihe_oooao APEdist_aaaa M3A Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 6OBBA 1.904 Pseudo DFGin‑None DFGAsp-rot-out out-na out-out TYR APEdihe_oooao APEdist_aaaa M3Y Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 6OBFA 1.71 Pseudo DFGin‑None DFGAsp-rot-out out-na out-out TYR APEdihe_oooao APEdist_aaaa M4G Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 6OBLA 2.061 Pseudo DFGin‑None DFGAsp-rot-out out-na out-out TYR APEdihe_oooao APEdist_aaaa M4P Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 6OCCA 2.03 Pseudo DFGin‑None DFGAsp-rot-out out-na out-out TYR APEdihe_oooao APEdist_aaaa M57 Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 6XJKA 2.024 Pseudo DFGin‑None DFGAsp-rot-out out-na out-out TYR APEdihe_oooao APEdist_aaaa V4D Type1 539 - 807 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 7JYOA 2.161 Pseudo DFGin‑None DFGAsp-rot-out in-na out-out TYR APEdihe_oooao APEdist_aaaa VPS Type1 539 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 7JYQA 1.859 Pseudo DFGin‑None DFGAsp-rot-out out-na out-out TYR APEdihe_oooao APEdist_aaaa VPJ Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 7SZWA 1.906 Pseudo DFGin‑None DFGAsp-rot-out out-na out-out TYR APEdihe_oooao APEdist_aaaa DVY Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 7T0PA 2.04 Pseudo DFGin‑None DFGAsp-rot-out out-na out-out TYR APEdihe_oooao APEdist_aaaa E3W Type1 536 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 7T0PB 2.04 Pseudo DFGin‑None DFGAsp-rot-out out-na out-out TYR APEdihe_oooao APEdist_aaaa E3W Type1 536 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 7T1TA 2.08 Pseudo DFGin‑None DFGAsp-rot-out out-na out-out TYR APEdihe_oooao APEdist_aaaa E8I Type1 536 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8B9HA 1.5 Pseudo DFGin‑None DFGAsp-rot-out out-na out-out TYR APEdihe_oooao APEdist_aaaa Q7F Type1 536 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8BA3A 1.4 Pseudo DFGin‑None DFGAsp-rot-out out-na out-out TYR APEdihe_oooao APEdist_aaaa Q8U Type1 536 - 812 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8EX0A 1.85 Pseudo DFGin‑None DFGAsp-rot-out in-na out-out TYR APEdihe_oooao APEdist_aaaa AQG Type1 536 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8EX1A 1.5 Pseudo DFGin‑None DFGAsp-rot-out in-na out-out TYR APEdihe_oooao APEdist_aaaa AD5 Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8EX2A 1.9 Pseudo DFGin‑None DFGAsp-rot-out in-na out-out TYR APEdihe_oooao APEdist_aaaa Q2Q Type1 536 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 9ND5A 2.4 Pseudo DFGin‑None DFGAsp-rot-out out-na out-out TYR APEdihe_oooao APEdist_aaaa A1BXA Type1 536 - 809 0 None None Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 9ND3A 1.62 Pseudo DFGin‑None DFGAsp-rot-out out-na out-out TYR APEdihe_oooao APEdist_aaaa A1BW6 Type1 536 - 808 0 None None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5TQ3A 2.69 Inactive DFGin‑None DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 7GZ Type1.5_Back 843 - 1132 0 PTR1007,PTR1008 M1073S,F1076T,I1126V Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5TQ3B 2.69 Inactive DFGin‑None DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 7GZ Type1.5_Back 843 - 1132 0 PTR1007,PTR1008 M1073S,F1076T,I1126V Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 7RN6A 1.5 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-out TYR APEdihe_nioai APEdist_aaaa 046 Type2 839 - 1130 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3UGCA 1.34 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-out TYR APEdihe_oioai APEdist_aaaa 046 Type2 843 - 1129 0 None Y1007F,Y1008F Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 7TEUA 1.45 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-out TYR APEdihe_oioai APEdist_aaaa I6C Type2 843 - 1131 0 None Y1007F,Y1008F Tyrosine-protein kinase JAK2
TYR JAK3-2 JAK3_HUMAN 7C3NA 1.98 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa FHX Type1 814 - 1102 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 3LXKA 2.0 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa MI1 Type1 815 - 1098 0 None C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN AF-P52333-K2A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 814 - 1105 0 None None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN AF-P52333-K4A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 814 - 1105 0 None None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 6HZVA 2.46 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa GYW Type1 815 - 1098 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 6HZVB 2.46 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa GYW Type1 815 - 1099 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 6HZVC 2.46 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa GYW Type1 815 - 1098 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 6HZVD 2.46 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa GYW Type1 815 - 1098 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 5W86A 2.61 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 9YV Type1 814 - 1098 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 5W86B 2.61 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 9YV Type1 816 - 1098 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 5W86C 2.61 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa 9YV Type1 814 - 1099 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 5W86D 2.61 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 9YV Type1 814 - 1099 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 6AAKA 2.67 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 9T6 Type1 815 - 1098 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 6AAKB 2.67 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 9T6 Type1 815 - 1100 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 6AAKC 2.67 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 9T6 Type1 814 - 1099 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 6AAKD 2.67 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 9T6 Type1 814 - 1098 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 3ZC6A 2.42 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_noiai APEdist_aaaa VFC Type1 814 - 1100 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 3ZC6B 2.42 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa VFC Type1 813 - 1100 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 3ZC6C 2.42 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa VFC Type1 814 - 1100 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 3ZC6D 2.42 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa VFC Type1 814 - 1100 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 3ZEPA 2.35 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 1NX Type1 814 - 1098 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 3ZEPB 2.35 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 1NX Type1 814 - 1100 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 3ZEPC 2.35 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa 1NX Type1 814 - 1100 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 3ZEPD 2.35 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 1NX Type1 814 - 1099 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 7UYVA 2.15 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa OV5 Type1 814 - 1100 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 7UYVB 2.15 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa OV5 Type1 814 - 1100 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 7UYVC 2.15 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa OV5 Type1 812 - 1100 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 7UYVD 2.15 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa OV5 Type1 814 - 1100 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 4RIOA 2.69 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 3QX Type1 815 - 1099 0 None C811S,C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 5VO6A 2.65 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa 9J4 Type1 815 - 1099 0 None C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 5WFJA 2.48 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 9Z4 Type1 817 - 1099 0 None C811S,C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 6NY4A 2.33 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa Z3A Type1 815 - 1099 0 None C811S,C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 4HVDA 1.85 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 933 Type1 815 - 1101 0 None C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 4HVGA 2.75 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 19Q Type1 814 - 1103 0 None C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 4HVHA 2.3 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 19R Type1 814 - 1102 0 None C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 4HVIA 2.4 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 19S Type1 815 - 1101 0 None C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 4I6QA 1.85 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 1DT Type1 815 - 1102 0 None C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 4QT1A 2.4 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 3C9 Type1 814 - 1102 0 None C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 3PJCA 2.2 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa PJC Type1 815 - 1104 0 None None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 5TOZA 1.98 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 7H4 Type1 815 - 1100 0 None None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 5TTSA 2.34 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 7KU Type1 814 - 1100 0 None C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 5TTUA 1.72 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 7KV Type1 815 - 1099 0 None C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 5TTVA 1.93 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 7KX Type1 814 - 1100 0 None C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 6DA4A 2.9 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa G4V Type1 815 - 1099 0 None C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 6DB3A 1.97 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa G54 Type1 814 - 1100 0 None C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 6DB4A 1.662 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa G4Y Type1 814 - 1100 0 None C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 6DUDA 1.66 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa HB4 Type1 814 - 1100 0 None C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 7Q6HAAA 1.749 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 934 Type1 814 - 1100 0 None None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 3LXLA 1.74 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa IZA Type1 814 - 1098 0 None C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 4V0GB 3.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa G9B Type1 816 - 1098 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 4V0GA 3.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa G9B Type1 817 - 1098 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 1YVJA 2.55 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 4ST Type1 814 - 1103 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 4Z16A 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa 4LH Type1 814 - 1103 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 4Z16B 2.9 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 4LH Type1 814 - 1103 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 4Z16C 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa 4LH Type1 814 - 1103 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 4Z16D 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa 4LH Type1 814 - 1103 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 4QPSA 1.8 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa 37Q Type1 814 - 1100 0 None D949A,C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 4QPSC 1.8 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 37Q Type1 814 - 1102 0 None D949A,C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 5LWMA 1.55 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 79T Type1 814 - 1103 0 None None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 6GL9A 1.7 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa F3W Type1 812 - 1103 0 None None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 6GL9B 1.7 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa F3W Type1 813 - 1103 0 None None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 6GLAA 1.92 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa F4B Type1 813 - 1103 0 None None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 6GLAB 1.92 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa F4B Type1 813 - 1103 0 None None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 6GLBA 2.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa F48 Type1 813 - 1103 0 None None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 6GLBB 2.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa F48 Type1 813 - 1103 0 None None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 7APFA 1.95 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa RQZ Type1 814 - 1103 0 None None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 7APFB 1.95 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa RQZ Type1 814 - 1103 0 None None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 7APGA 2.4 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa RQT Type1 813 - 1103 0 None None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 7APGB 2.4 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa RQT Type1 814 - 1103 0 None None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 7APGC 2.4 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa RQT Type1 812 - 1103 0 None None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 7APGD 2.4 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa RQT Type1 815 - 1103 0 None None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 9R5ZA 1.8 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa A1JJU Type1 822 - 1101 0 None None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 9R5ZB 1.8 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa A1JJU Type1 816 - 1101 0 None None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 5LWNA 1.6 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 79R, 79S Type1, Type1 814 - 1103 0 None None Tyrosine-protein kinase JAK3
TYR KDR VGFR2_HUMAN AF-P35968-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 826 - 1170 0 None None Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN AF-P35968-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 826 - 1170 0 None None Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3CJGA 2.25 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_nnnao APEdist_aaaa KIM Type1 816 - 1168 0 None None Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 2P2HA 1.95 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_nooai APEdist_aaaa 994 Type1 815 - 1172 0 PTR1054,PTR1059 C817A,V916T,E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3WZDA 1.57 Inactive DFGin‑BLBplus DFGAsp-rot-out in-in none-out TYR APEdihe_nnoai APEdist_aaaa LEV Type1 820 - 1167 0 None T940V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3B8RA 2.7 Inactive DFGin‑BLBplus DFGAsp-rot-out in-in none-out TYR APEdihe_nnoai APEdist_aaaa 887 Type1 818 - 1171 0 PTR1054,PTR1059 C817A,V916T,E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3B8RB 2.7 Inactive DFGin‑BLBplus DFGAsp-rot-out in-in none-out TYR APEdihe_nnoai APEdist_aaaa 887 Type1 821 - 1166 0 PTR1054,PTR1059 C817A,V916T,E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 1VR2A 2.4 Inactive DFGin‑None DFGAsp-rot-in in-in none-out TYR APEdihe_iioai APEdist_aaaa No_ligand No_ligand 820 - 1168 0 PTR1059 E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 1Y6AA 2.1 Inactive DFGinter‑None DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa AAZ Type1 820 - 1167 0 None None Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 1Y6BA 2.1 Inactive DFGinter‑None DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa AAX Type1 819 - 1168 0 None None Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 4AG8A 1.95 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa AXI Type1 816 - 1168 0 None E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 4AGDA 2.81 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa B49 Type1 802 - 1169 0 None E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3CPBB 2.7 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-out TYR APEdihe_nnoai APEdist_aaaa C92 Type1 820 - 1165 0 PTR1054,PTR1059 C817A,V916T,E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 2XIRA 1.5 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 00J Type1.5_Back 816 - 1168 0 None E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 4AGCA 2.0 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa AXI Type1.5_Back 801 - 1169 0 None E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3WZEA 1.9 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa BAX Type2 815 - 1167 0 None T940V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 2OH4A 2.05 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-out TYR APEdihe_iioai APEdist_aaaa GIG Type2 816 - 1171 0 PTR1054,PTR1059 None Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 2P2IA 2.4 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa 608 Type2 817 - 1172 0 PTR1054,PTR1059 C817A,E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3EFLA 2.2 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa 706 Type2 817 - 1171 0 PTR1054,PTR1059 C817A,E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3EFLB 2.2 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-out TYR APEdihe_nnoai APEdist_aaaa 706 Type2 821 - 1165 0 PTR1054,PTR1059 C817A,E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 5EW3A 2.5 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa 5T2 Type2 821 - 1168 0 None None Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 5EW3B 2.5 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa 5T2 Type2 820 - 1165 0 None None Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 6GQOA 1.87 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa F82 Type2 811 - 1168 0 None None Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 6GQPA 2.09 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa F88 Type2 821 - 1168 0 None None Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 6GQQA 1.52 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa F8B Type2 813 - 1167 0 None None Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 6XVJA 1.78 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa O35 Type2 813 - 1167 0 None E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 6XVKA 1.99 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa O3E Type2 821 - 1168 0 None E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 4ASDA 2.03 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa BAX Type2 807 - 1168 0 None E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 4ASEA 1.83 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa AV9 Type2 807 - 1169 0 None E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3VHEA 1.55 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 42Q Type2 811 - 1169 0 None None Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3VHKA 2.49 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa BPK Type2 814 - 1168 0 None None Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 2QU5A 2.95 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-out TYR APEdihe_oooai APEdist_aaaa 276 Type2 816 - 1170 0 PTR1054,PTR1059 C817A,V916T,E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 2QU6A 2.1 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa 857 Type2 817 - 1171 0 PTR1054,PTR1059 C817A,V916T,E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 2RL5A 2.65 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-out TYR APEdihe_oooai APEdist_aaaa 2RL Type2 815 - 1171 0 PTR1054,PTR1059 C817A,V916T,E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3B8QB 2.75 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-out TYR APEdihe_nnoai APEdist_aaaa 900 Type2 820 - 1166 0 PTR1054,PTR1059 C817A,V916T,E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3BE2A 1.75 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa RAJ Type2 815 - 1171 0 PTR1054,PTR1059 C817A,V916T,E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3CP9A 2.5 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-out TYR APEdihe_nnoai APEdist_aaaa C19 Type2 817 - 1171 0 PTR1054,PTR1059 C817A,V916T,E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3CP9B 2.5 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-out TYR APEdihe_nnoai APEdist_aaaa C19 Type2 819 - 1165 0 PTR1054,PTR1059 C817A,V916T,E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3CPCB 2.4 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-out TYR APEdihe_nnoai APEdist_aaaa C52 Type2 820 - 1165 0 PTR1054,PTR1059 C817A,V916T,E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3DTWB 2.9 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-out TYR APEdihe_nooai APEdist_aaaa A96 Type2 820 - 1166 0 PTR1054,PTR1059 C817A,V916T,E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3EWHA 1.6 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-none TYR APEdihe_nniai APEdist_aaaa K11 Type2 815 - 1171 0 None C817A,V916T,E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3U6JA 2.15 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 03X Type2 815 - 1171 0 None V916T,E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3C7QA 2.1 Inactive DFGout‑None DFGAsp-rot-in in-in none-out TYR APEdihe_iioai APEdist_aaaa XIN Type1 819 - 1171 0 PTR1054,PTR1059 None Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 2P2IB 2.4 Inactive DFGout‑None DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa 608 Type1 820 - 1168 0 PTR1054,PTR1059 C817A,E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3VNTA 1.64 Inactive DFGout‑None DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 0JA Type2 812 - 1168 0 None None Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3VO3A 1.52 Inactive DFGout‑None DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 0KF Type2 812 - 1168 0 None None Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 2QU6B 2.1 Inactive DFGout‑None DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa 857 Type2 822 - 1165 0 PTR1054,PTR1059 C817A,V916T,E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3B8QA 2.75 Inactive DFGout‑None DFGAsp-rot-in in-in none-out TYR APEdihe_nnoai APEdist_aaaa 900 Type2 818 - 1171 0 PTR1054,PTR1059 C817A,V916T,E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3CPBA 2.7 Inactive DFGout‑None DFGAsp-rot-in in-in none-out TYR APEdihe_nnoai APEdist_aaaa C92 Type2 819 - 1171 0 PTR1054,PTR1059 C817A,V916T,E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3CPCA 2.4 Inactive DFGout‑None DFGAsp-rot-in in-out none-out TYR APEdihe_nnoai APEdist_aaaa C52 Type2 820 - 1171 0 PTR1054,PTR1059 C817A,V916T,E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3DTWA 2.9 Inactive DFGout‑None DFGAsp-rot-in in-in none-out TYR APEdihe_nnoai APEdist_aaaa A96 Type2 818 - 1171 0 PTR1054,PTR1059 C817A,V916T,E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3CJFA 2.15 Inactive None‑None DFGAsp-rot-out in-out in-none TYR APEdihe_nnnai APEdist_aaaa SAV Type1 817 - 1168 0 None None Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 1YWNA 1.71 Inactive None‑None DFGAsp-rot-in in-in none-out TYR APEdihe_iioai APEdist_aaaa LIF Type1 820 - 1171 0 PTR1054,PTR1059 E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3VIDA 2.3 Inactive None‑None DFGAsp-rot-in in-in none-out TYR APEdihe_iioai APEdist_aaaa 4TT Type1 813 - 1168 0 None None Vascular endothelial growth factor receptor 2
TYR KIT KIT_HUMAN 1PKGA 2.9 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-out TYR APEdihe_oiiai APEdist_aaaa ADP ATPlike 567 - 927 0 PTR568,PTR570 None Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 1PKGB 2.9 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa ADP ATPlike 566 - 929 0 PTR568,PTR570 None Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN AF-P10721-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 581 - 934 0 None None Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN AF-P10721-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 581 - 934 0 None None Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 7KHJA 2.8 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa WEG Type1 566 - 931 0 None None Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 7KHJB 2.8 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa WEG Type1 571 - 930 0 None None Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 7KHKA 2.34 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa WEJ Type1 566 - 931 0 None None Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8PQGA 2.4 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 9JI Type1 566 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,T670I,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8PQGC 2.4 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 9JI Type1 565 - 932 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,T670I,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8PQ9A 1.7 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 9JI Type1 566 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8PQ9C 1.7 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 9JI Type1 565 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8PQAA 1.65 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 98A Type1 566 - 930 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8PQAC 1.65 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 98A Type1 566 - 932 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8PQBA 1.87 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa 9XO Type1 567 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8PQCA 1.77 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 9OO Type1 566 - 932 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8PQCB 1.77 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 9OO Type1 566 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8PQDA 1.5 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 9VV Type1 566 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8PQDB 1.5 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 9VV Type1 566 - 932 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8PQEB 2.0 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa 9WU Type1 566 - 930 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8PQFA 1.9 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 9KI Type1 566 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8PQFC 1.9 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 9KI Type1 566 - 932 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8S19A 2.3 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa STU Type1 566 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8S19B 2.3 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa STU Type1 566 - 930 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8S1AA 1.85 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 6T2 Type1 565 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8S1AB 1.85 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 6T2 Type1 566 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 7KHKB 2.34 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa WEJ Type1.5_Back 567 - 929 0 None None Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8S13A 2.0 Inactive DFGout‑BBAminus DFGAsp-rot-in in-none out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 554 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8S14A 1.5 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa B49 Type1 554 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8S15A 2.4 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa XIN Type1 554 - 929 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 3G0FA 2.6 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa B49 Type1 566 - 930 0 None D816H Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 3G0FB 2.6 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa B49 Type1 564 - 930 0 None D816H Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 7ZW8A 2.119 Inactive DFGout‑BBAminus DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa K3R Type1 554 - 932 0 None None Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6KLAA 2.109 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa DJX Type1 554 - 931 0 None None Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 4HVSA 1.9 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 647 Type2 551 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,I690H,C691S,K693D,Q694T,E695S,I756S,L762N,V825D,C844S,L890S,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 7KHGA 2.15 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa P31 Type2 547 - 931 0 None None Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8S16A 1.85 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa STI Type2 566 - 932 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8S16B 1.85 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa STI Type2 578 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8S17A 2.2 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 0LI Type2 567 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8S17B 2.2 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 0LI Type2 578 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8S18A 2.1 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa A1H4U Type2 568 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8S18B 2.1 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa A1H4U Type2 578 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6GQJA 2.33 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa F82 Type2 567 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6GQJB 2.33 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa F82 Type2 572 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6GQKA 2.31 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa F88 Type2 567 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6GQKB 2.31 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa F88 Type2 572 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6GQLA 2.01 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa F8B Type2 568 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6GQLB 2.01 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa F8B Type2 577 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6GQMA 2.0 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa F8H Type2 569 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6GQMB 2.0 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa F8H Type2 577 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6XV9A 3.38 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa O35 Type2 566 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6XV9B 3.38 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa O35 Type2 572 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6XVAA 2.3 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa O2K Type2 569 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6XVAB 2.3 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa O2K Type2 577 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6XVBA 2.15 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa O2H Type2 569 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6XVBB 2.15 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa O2H Type2 577 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6HH1A 2.25 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-in TYR APEdihe_iiiai APEdist_aaaa G4E Type2 565 - 929 0 None None Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6MOBA 1.8 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa JWY Type2 567 - 930 0 None None Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 1T46A 1.6 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa STI Type2 565 - 933 0 None None Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 4U0IA 2.0 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 0LI Type2 565 - 933 0 None None Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 7ZY6A 3.09 Inactive DFGout‑BBAminus DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa KCI Type2 557 - 932 0 None None Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6ITTA 2.103 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa AWO Type2 563 - 932 0 None None Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6ITTB 2.103 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa AWO Type2 566 - 932 0 None None Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6ITVA 1.881 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa AWO Type2 569 - 935 0 PTR570 None Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8S1BB 2.0 Inactive DFGout‑BBAminus DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa K3R, K3R, K3R Type2, Allosteric, Allosteric 565 - 930 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 1T45A 1.9 Inactive DFGout‑None DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 547 - 935 0 None None Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 3G0EA 1.6 Inactive DFGout‑None DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa B49 Type1 544 - 931 0 None None Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8S1BA 2.0 Inactive DFGout‑None DFGAsp-rot-in in-in none-in TYR APEdihe_iiiai APEdist_aaaa K3R Type2 565 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8PQEA 2.0 Inactive None‑None DFGAsp-rot-out in-in none-none TYR APEdihe_niiai APEdist_aaaa 9WU Type1 566 - 930 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR LCK LCK_HUMAN 1QPCA 1.6 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa ANP ATPlike 231 - 502 0 PTR394 None Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN AF-P06239-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 237 - 504 0 None None Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN AF-P06239-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 237 - 504 0 None None Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN 3LCKA 1.7 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 231 - 501 0 PTR394 None Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN 2OF2A 2.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 547 Type1 231 - 501 0 None None Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN 2OF4A 2.7 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 979 Type1 231 - 501 0 None None Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN 3BYOA 2.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa AM9 Type1 231 - 501 0 PTR394 None Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN 2OFUA 2.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 1N9 Type1 229 - 501 0 PTR394 None Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN 1QPEA 2.0 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa PP2 Type1 231 - 501 0 PTR394 None Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN 1QPJA 2.2 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa STU Type1 236 - 501 0 PTR394 None Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN 2ZM1A 2.1 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa KSF Type1 231 - 501 0 PTR394 None Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN 2ZM4A 2.7 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa KSM Type1 231 - 501 0 PTR394 None Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN 2ZYBA 2.55 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa KSL Type1 231 - 501 0 PTR394 None Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN 3AC1A 1.99 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa KZI Type1 231 - 502 0 PTR394 None Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN 3AC2A 2.1 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa KSE Type1 231 - 502 0 PTR394 None Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN 3AC3A 2.55 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa KSH Type1 231 - 502 0 PTR394 None Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN 3AC4A 2.7 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa KZL Type1 231 - 502 0 PTR394 None Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN 3AC5A 2.5 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa KZM Type1 231 - 502 0 PTR394 None Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN 3AC8A 2.3 Inactive DFGin‑BLAminus DFGAsp-rot-out in-out in-in TYR APEdihe_iiiai APEdist_aaaa KSK Type1 231 - 501 0 PTR394 None Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN 3ACJA 2.2 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa KSS Type1 231 - 502 0 PTR394 None Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN 3ACKA 2.6 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa KSR Type1 231 - 502 0 PTR394 None Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN 3AD4A 2.2 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa KBM Type1 231 - 502 0 PTR394 None Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN 3AD5A 2.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 5PB Type1 230 - 502 0 PTR394 None Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN 3AD6A 2.15 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa KSC Type1 230 - 502 0 PTR394 None Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN 3KXZA 2.37 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 925 Type1 238 - 501 0 PTR394 None Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN 1QPDA 2.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa STU Type1 231 - 502 0 PTR394 None Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN 3BYMA 2.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa AM0 Type1.5_Back 230 - 501 0 PTR394 None Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN 3KMMA 2.8 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa LHL Type1.5_Back 231 - 501 0 PTR394 Y505F Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN 3B2WA 2.3 Inactive DFGin‑BLBminus DFGAsp-rot-out in-in out-out TYR APEdihe_oiiai APEdist_aaaa 9NH Type1 238 - 500 0 None None Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN 3MPMA 1.95 Inactive DFGin‑BLBplus DFGAsp-rot-out in-in out-out TYR APEdihe_nnoai APEdist_aaaa 5LK Type1 238 - 498 0 None D364N Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN 4C3FA 1.72 Inactive DFGin‑BLBplus DFGAsp-rot-out in-in out-none TYR APEdihe_nniai APEdist_aaaa 7KW Type1 238 - 498 0 None D364N Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN 6PDJA 1.81 Inactive DFGout‑BBAminus DFGAsp-rot-in out-none in-in TYR APEdihe_iiiai APEdist_aaaa ODJ Type1.5_Front 225 - 500 0 PTR394 None Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN 2OG8A 2.3 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa 1N8 Type2 237 - 499 0 None None Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN 2OG8B 2.3 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa 1N8 Type2 237 - 499 0 None None Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN 3BYSA 2.2 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-out TYR APEdihe_nnnao APEdist_aaaa AM5 Type2 230 - 501 0 None None Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN 3BYUA 2.3 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-out TYR APEdihe_nioao APEdist_aaaa AM6 Type2 231 - 501 0 None None Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN 2PL0A 2.8 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa STI Type2 231 - 498 0 None None Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN 2OFVA 2.0 Inactive DFGout‑None DFGAsp-rot-in in-in none-none TYR APEdihe_nnnan APEdist_aaaa 242 Type2 232 - 498 0 None None Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN 2OFVB 2.0 Inactive DFGout‑None DFGAsp-rot-in in-in out-none TYR APEdihe_nnnai APEdist_aaaa 242 Type2 232 - 498 0 None None Tyrosine-protein kinase Lck
TYR LMTK2 LMTK2_HUMAN AF-Q8IWU2-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-na in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 129 - 417 0 None None Serine/threonine-protein kinase LMTK2
TYR LMTK2 LMTK2_HUMAN AF-Q8IWU2-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-na in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 129 - 417 0 None None Serine/threonine-protein kinase LMTK2
TYR LMTK3 LMTK3_HUMAN AF-Q96Q04-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 125 - 418 0 None None Serine/threonine-protein kinase LMTK3
TYR LMTK3 LMTK3_HUMAN AF-Q96Q04-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 125 - 418 0 None None Serine/threonine-protein kinase LMTK3
TYR LMTK3 LMTK3_HUMAN 6SEQA 2.1 Inactive DFGout‑BBAminus DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 130 - 413 0 None None Serine/threonine-protein kinase LMTK3
TYR LTK LTK_HUMAN AF-P29376-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 502 - 787 0 None None Leukocyte tyrosine kinase receptor
TYR LTK LTK_HUMAN AF-P29376-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 502 - 787 0 None None Leukocyte tyrosine kinase receptor
TYR LYN LYN_HUMAN 5XY1A 2.7 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa 8H0 Type1.5_Back 239 - 502 0 None None Tyrosine-protein kinase Lyn
TYR LYN LYN_HUMAN AF-P07948-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 239 - 507 0 None None Tyrosine-protein kinase Lyn
TYR LYN LYN_HUMAN AF-P07948-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 239 - 507 0 None None Tyrosine-protein kinase Lyn
TYR LYN LYN_HUMAN 3A4OX 3.0 Inactive DFGin‑None DFGAsp-rot-in in-in in-out TYR APEdihe_ooiai APEdist_aaaa STU Type1 238 - 505 0 None None Tyrosine-protein kinase Lyn
TYR MATK MATK_HUMAN AF-P42679-K1A -1.0 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa No_ligand No_ligand 227 - 488 0 None None Megakaryocyte-associated tyrosine-protein kinase
TYR MATK MATK_HUMAN AF-P42679-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 227 - 488 0 None None Megakaryocyte-associated tyrosine-protein kinase
TYR MERTK MERTK_HUMAN AF-Q12866-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 579 - 864 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN AF-Q12866-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 579 - 864 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 7AAZA 1.855 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-out TYR APEdihe_oiiai APEdist_aaaa R6K Type1.5_Front 574 - 863 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 9BHIA 2.07 Inactive DFGin‑BLAminus DFGAsp-rot-in out-out in-out TYR APEdihe_oiiai APEdist_aaaa A1APF Type1.5_Front 578 - 864 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 9BHJA 2.294 Inactive DFGin‑BLAminus DFGAsp-rot-out out-out in-out TYR APEdihe_oiiai APEdist_aaaa A1APG Type1.5_Front 578 - 862 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 9BHKA 2.106 Inactive DFGin‑BLAminus DFGAsp-rot-out out-out in-out TYR APEdihe_oiiai APEdist_aaaa A1APH Type1.5_Front 578 - 862 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 7M5ZB 3.06 Inactive DFGin‑BLAplus DFGAsp-rot-in out-out none-none TYR APEdihe_nnnai APEdist_aaaa YR7 Type1 574 - 862 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 7AVYA 2.31 Inactive DFGin‑BLBminus DFGAsp-rot-in out-out none-none TYR APEdihe_nnnai APEdist_aaaa S4E Type1 576 - 863 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 7AW2A 2.1 Inactive DFGin‑BLBminus DFGAsp-rot-in out-out none-none TYR APEdihe_nnnai APEdist_aaaa S4W Type1.5_Front 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 7OLSA 1.89 Inactive DFGin‑BLBminus DFGAsp-rot-out out-out none-none TYR APEdihe_nnnai APEdist_aaaa VJZ Type1.5_Front 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 7OLVA 2.13 Inactive DFGin‑BLBminus DFGAsp-rot-out out-out none-none TYR APEdihe_nnnai APEdist_aaaa VK2 Type1.5_Front 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 7OLXA 1.98 Inactive DFGin‑BLBminus DFGAsp-rot-in out-out none-none TYR APEdihe_nnnai APEdist_aaaa VK5 Type1.5_Front 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 2P0CA 2.4 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none none-none TYR APEdihe_nnnai APEdist_aaaa ANP ATPlike 575 - 861 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 2P0CB 2.4 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none none-none TYR APEdihe_nnnai APEdist_aaaa ANP ATPlike 575 - 861 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 3BRBA 1.9 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa ADP ATPlike 575 - 861 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 3BRBB 1.9 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nnnai APEdist_aaaa ADP ATPlike 575 - 863 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 7CQEA 2.69 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nnnai APEdist_aaaa YDJ Type1 578 - 861 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 7CQEC 2.69 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nnnai APEdist_aaaa YDJ Type1 578 - 861 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 7DXLA 3.146 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-out TYR APEdihe_nnoai APEdist_aaaa E56 Type1 575 - 863 0 None I650M Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 7DXLB 3.146 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nnnai APEdist_aaaa E56 Type1 575 - 863 0 None I650M Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 3BPRA 2.8 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nnnai APEdist_aaaa OLP Type1 575 - 863 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 3BPRB 2.8 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nnnai APEdist_aaaa OLP Type1 576 - 863 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 3BPRC 2.8 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nnnai APEdist_aaaa OLP Type1 575 - 863 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 3BPRD 2.8 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nnnai APEdist_aaaa OLP Type1 575 - 863 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 4M3QB 2.718 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out none-none TYR APEdihe_nnnai APEdist_aaaa 24K Type1 577 - 861 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 4MHAA 2.59 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out none-none TYR APEdihe_nnnai APEdist_aaaa 4MH Type1 580 - 863 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 5K0KA 2.545 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out none-none TYR APEdihe_nnnai APEdist_aaaa 6Q1 Type1 577 - 863 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 5K0XA 2.231 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out none-none TYR APEdihe_nnnai APEdist_aaaa K0X Type1 576 - 863 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 6MEPA 2.893 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out none-none TYR APEdihe_nnnai APEdist_aaaa 9VS Type1.5_Back 576 - 863 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 7AVXA 2.44 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa S4K Type1.5_Front 577 - 862 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 5TD2B 2.68 Inactive DFGin‑None DFGAsp-rot-in out-out none-none TYR APEdihe_nnnai APEdist_aaaa No_ligand No_ligand 577 - 861 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 4MH7B 2.51 Inactive DFGin‑None DFGAsp-rot-in out-out none-none TYR APEdihe_nnnai APEdist_aaaa No_ligand No_ligand 577 - 862 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 5TC0B 2.24 Inactive DFGin‑None DFGAsp-rot-in out-out none-none TYR APEdihe_nnnai APEdist_aaaa No_ligand No_ligand 578 - 861 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 7AB0A 1.74 Inactive DFGin‑None DFGAsp-rot-in out-out none-none TYR APEdihe_nnnai APEdist_aaaa No_ligand No_ligand 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 5TD2A 2.68 Inactive DFGin‑None DFGAsp-rot-in none-none none-none TYR APEdihe_nnnai APEdist_aaaa 7AE Type1 577 - 861 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 7OAMB 2.65 Inactive DFGin‑None DFGAsp-rot-out none-none none-none TYR APEdihe_nniai APEdist_aaaa V6H Type1 576 - 862 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 3TCPA 2.69 Inactive DFGin‑None DFGAsp-rot-in out-out none-none TYR APEdihe_nnnai APEdist_aaaa CKJ Type1 577 - 863 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 3TCPB 2.69 Inactive DFGin‑None DFGAsp-rot-in out-none none-none TYR APEdihe_nniai APEdist_aaaa CKJ Type1 576 - 861 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 4M3QA 2.718 Inactive DFGin‑None DFGAsp-rot-out none-none none-none TYR APEdihe_nnnai APEdist_aaaa 24K Type1 578 - 861 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 4MH7A 2.51 Inactive DFGin‑None DFGAsp-rot-in none-none none-none TYR APEdihe_nnnai APEdist_aaaa MH7 Type1 577 - 861 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 4MHAB 2.59 Inactive DFGin‑None DFGAsp-rot-in none-none none-none TYR APEdihe_nnnai APEdist_aaaa 4MH Type1 577 - 862 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 5K0KB 2.545 Inactive DFGin‑None DFGAsp-rot-out out-out none-none TYR APEdihe_nnnai APEdist_aaaa 6Q1 Type1 577 - 862 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 5TC0A 2.24 Inactive DFGin‑None DFGAsp-rot-in none-none none-none TYR APEdihe_nniai APEdist_aaaa 79Y Type1 578 - 861 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 5U6CA 2.1 Inactive DFGin‑None DFGAsp-rot-in out-out none-none TYR APEdihe_nnnai APEdist_aaaa 7YS Type1 572 - 864 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 5U6CB 2.1 Inactive DFGin‑None DFGAsp-rot-in out-out none-none TYR APEdihe_nniai APEdist_aaaa 7YS Type1 575 - 862 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 7AB1A 1.93 Inactive DFGin‑None DFGAsp-rot-out out-out none-none TYR APEdihe_nnnai APEdist_aaaa C6F Type1 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 7AB2A 1.78 Inactive DFGin‑None DFGAsp-rot-in out-out none-none TYR APEdihe_nnnai APEdist_aaaa R6N Type1 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 7AVZA 2.04 Inactive DFGin‑None DFGAsp-rot-in out-out none-none TYR APEdihe_nnnai APEdist_aaaa S4N Type1 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 7AW0A 1.893 Inactive DFGin‑None DFGAsp-rot-out out-out none-none TYR APEdihe_nnnai APEdist_aaaa S4Q Type1 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 7AW3A 1.99 Inactive DFGin‑None DFGAsp-rot-in out-out none-none TYR APEdihe_nnnai APEdist_aaaa S4Z Type1 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 7M5ZA 3.06 Inactive DFGin‑None DFGAsp-rot-in in-out none-none TYR APEdihe_nnnai APEdist_aaaa YR7 Type1 577 - 862 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 6MEPB 2.893 Inactive DFGin‑None DFGAsp-rot-out out-out none-none TYR APEdihe_nnnai APEdist_aaaa 9VS Type1.5_Back 578 - 862 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 9KS9B 2.8 Inactive DFGout‑BBAminus DFGAsp-rot-in out-none none-none TYR APEdihe_nnnai APEdist_aaaa A1L6L Type1 577 - 863 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 7XHYA 2.16 Inactive DFGout‑BBAminus DFGAsp-rot-in out-out none-none TYR APEdihe_nnnai APEdist_aaaa E0X Type1 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 7AAYA 1.87 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-out TYR APEdihe_nnoai APEdist_aaaa L1X Type2 571 - 862 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 9KRYB 2.25 Inactive DFGout‑BBAminus DFGAsp-rot-in out-none none-none TYR APEdihe_nnnai APEdist_aaaa A1L6J Type2 580 - 863 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 7AW4A 1.98 Inactive DFGout‑BBAminus DFGAsp-rot-in out-out none-none TYR APEdihe_nnnai APEdist_aaaa S5E Type3 576 - 862 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 7AW4B 1.98 Inactive DFGout‑BBAminus DFGAsp-rot-in out-out none-none TYR APEdihe_nnnai APEdist_aaaa S5E Type3 574 - 862 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 7AVXB 2.44 Inactive DFGout‑None DFGAsp-rot-out out-out none-none TYR APEdihe_nnnai APEdist_aaaa S4K Type1 577 - 862 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 9KRZA 2.6 Inactive DFGout‑None DFGAsp-rot-in out-none none-none TYR APEdihe_nnnai APEdist_aaaa A1L6K Type1.5_Front 577 - 864 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 9KRZB 2.6 Inactive DFGout‑None DFGAsp-rot-in out-none none-none TYR APEdihe_nnnai APEdist_aaaa A1L6K Type1.5_Front 575 - 863 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 9KRYA 2.25 Inactive DFGout‑None DFGAsp-rot-in out-out none-none TYR APEdihe_nnnai APEdist_aaaa A1L6J Type2 580 - 863 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 9KS9A 2.8 Inactive DFGout‑None DFGAsp-rot-in out-out none-none TYR APEdihe_nnnai APEdist_aaaa A1L6L Type2 576 - 862 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 7AAXA 1.762 Inactive DFGout‑None DFGAsp-rot-in out-out none-none TYR APEdihe_nnnai APEdist_aaaa R6H Type2 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 7AW1A 1.98 Inactive DFGout‑None DFGAsp-rot-in out-out none-none TYR APEdihe_nnnai APEdist_aaaa S4T Type2 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 7OAMA 2.65 Inactive None‑None DFGAsp-rot-out out-none none-none TYR APEdihe_nniai APEdist_aaaa No_ligand No_ligand 575 - 863 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 5K0XB 2.231 Inactive None‑None DFGAsp-rot-in out-out none-none TYR APEdihe_nnnai APEdist_aaaa K0X Type1 575 - 863 0 None None Tyrosine-protein kinase Mer
TYR MET MET_HUMAN 4IWDA 1.99 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa AME, 1JC Allosteric, Type1 1048 - 1348 0 PTR1234,PTR1235 None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3Q6WA 1.75 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa Q6W Type1 1050 - 1348 0 PTR1234,PTR1235 None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3R7OA 2.3 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa M61 Type1 1048 - 1348 0 PTR1234,PTR1235 None Hepatocyte growth factor receptor
TYR MET MET_HUMAN AF-P08581-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 1068 - 1347 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN AF-P08581-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 1068 - 1347 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3Q6UA 1.6 Inactive DFGin‑BLBminus DFGAsp-rot-out in-out none-none TYR APEdihe_nniai APEdist_aaaa AME Allosteric 1048 - 1348 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3DKCA 1.52 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa ATP ATPlike 1051 - 1360 0 None Y1194F,Y1234F,Y1235D Hepatocyte growth factor receptor
TYR MET MET_HUMAN 2G15A 2.15 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 1046 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 1R1WA 1.8 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-none TYR APEdihe_nniai APEdist_aaaa No_ligand No_ligand 1050 - 1360 0 None Y1194F,Y1234F,Y1235D,L1272L Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8AU3A 2.26 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-out TYR APEdihe_nnoai APEdist_aaaa 3E8 Type1 1052 - 1349 0 None Y1234E,Y1235E Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8AU3B 2.26 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-out TYR APEdihe_nnoai APEdist_aaaa 3E8 Type1 1056 - 1349 0 None Y1234E,Y1235E Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8AU5A 2.72 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa 3E8 Type1 1067 - 1346 0 None F1200I Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8AW1A 2.14 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-none TYR APEdihe_niiai APEdist_aaaa 3E8 Type1 1066 - 1345 0 None Y1235D Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8AW1B 2.14 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa 3E8 Type1 1064 - 1345 0 None Y1235D Hepatocyte growth factor receptor
TYR MET MET_HUMAN 9SZJA 2.289 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa A1JRF Type1 1070 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 4KNBA 2.4 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa 1RU Type1 1064 - 1344 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 4KNBB 2.4 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-none TYR APEdihe_nniai APEdist_aaaa 1RU Type1 1067 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 4KNBC 2.4 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa 1RU Type1 1060 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 4KNBD 2.4 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-none TYR APEdihe_nnnan APEdist_aaaa 1RU Type1 1064 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 4R1VA 1.2 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa 3E8 Type1 1055 - 1345 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 2WD1A 2.0 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa ZZY Type1 1055 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 4R1YA 2.0 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa 3EH Type1 1062 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3F66A 1.4 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa IHX Type1 1052 - 1349 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3F66B 1.4 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa IHX Type1 1062 - 1349 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 7B3QA 1.75 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-none TYR APEdihe_nnnai APEdist_aaaa SV5 Type1 1055 - 1344 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 7B3TA 2.23 Inactive DFGin‑BLBplus DFGAsp-rot-in out-none out-none TYR APEdihe_nniai APEdist_aaaa SVK Type1 1062 - 1344 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 7B3VA 1.93 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-none TYR APEdihe_nniai APEdist_aaaa SWB Type1 1057 - 1344 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 7B3WA 2.02 Inactive DFGin‑BLBplus DFGAsp-rot-in none-none out-in TYR APEdihe_iiiai APEdist_aaaa SVH Type1 1067 - 1344 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 7B3ZA 1.8 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-none TYR APEdihe_nnnai APEdist_aaaa SV8 Type1 1055 - 1344 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 7B40A 1.76 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-none TYR APEdihe_nnnai APEdist_aaaa SWN Type1 1055 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 7B41A 1.97 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-none TYR APEdihe_nniai APEdist_aaaa SWK Type1 1055 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 7B42A 1.8 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-none TYR APEdihe_nniai APEdist_aaaa SW8 Type1 1055 - 1344 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 7B43A 1.87 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-none TYR APEdihe_nnnai APEdist_aaaa SW5 Type1 1055 - 1344 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 7B43B 1.87 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-none TYR APEdihe_nnnai APEdist_aaaa SW5 Type1 1055 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 7B44A 1.76 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-none TYR APEdihe_nnnai APEdist_aaaa SVT Type1 1055 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 2WGJA 2.0 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa VGH Type1 1052 - 1345 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 2WKMA 2.2 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa PFY Type1 1059 - 1345 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3ZBXA 2.2 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa 6XE Type1 1059 - 1345 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3ZC5A 2.2 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa W9Z Type1 1052 - 1345 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3ZCLA 1.4 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa 5TF Type1 1052 - 1345 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3ZXZA 1.8 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa KRW Type1 1052 - 1345 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3ZZEA 1.87 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa 6XP Type1 1059 - 1345 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 4AOIA 1.9 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa 4K0 Type1 1052 - 1344 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 4AP7A 1.8 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa F47 Type1 1052 - 1345 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 6SDEA 2.49 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa V0L Type1 1068 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 7Y4TA 2.16 Inactive DFGin‑BLBplus DFGAsp-rot-in out-none out-in TYR APEdihe_iiiai APEdist_aaaa I90 Type1 1063 - 1345 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 7Y4UA 2.26 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa I94 Type1 1061 - 1344 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8GVJA 2.71 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa KGL Type1 1060 - 1344 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8K78A 2.67 Inactive DFGin‑BLBplus DFGAsp-rot-in out-none out-in TYR APEdihe_iiiai APEdist_aaaa IYC Type1 1048 - 1345 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 9IVBA 2.35 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa A1L3A Type1 1040 - 1344 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 9IVBB 2.35 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa A1L3A Type1 1045 - 1344 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3I5NA 2.0 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-none TYR APEdihe_niiai APEdist_aaaa B2D Type1 1052 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 4DEGA 2.0 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa 0JJ Type1 1052 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 4DEHA 2.0 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa 0JK Type1 1053 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 4DEIA 2.05 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa 0JL Type1 1053 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 4XMOA 1.75 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa 46G Type1 1051 - 1345 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 4XYFA 1.85 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa 44X Type1 1052 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 5EYCA 1.8 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa 5SZ Type1 1053 - 1345 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 5EYDA 1.85 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa 5T1 Type1 1052 - 1348 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 2RFSA 2.2 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa AM8 Type1 1067 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3CCNA 1.9 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa LKG Type1 1055 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3CD8A 2.0 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa L5G Type1 1054 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 4GG5A 2.423 Inactive DFGin‑BLBplus DFGAsp-rot-in out-none out-in TYR APEdihe_iiiai APEdist_aaaa 0J3 Type1 1064 - 1344 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 4GG7A 2.27 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa 0J8 Type1 1064 - 1344 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 5EOBA 1.75 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa 5QQ Type1 1055 - 1345 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 5YA5A 1.89 Inactive DFGin‑BLBplus DFGAsp-rot-in out-none out-in TYR APEdihe_iiiai APEdist_aaaa 6TD Type1 1057 - 1345 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 5UABA 1.9 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa 84M Type1 1029 - 1360 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 5UADA 2.25 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa 84P Type1 1029 - 1360 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 6UBWA 2.0 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa 84S Type1 1029 - 1360 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3DKGA 1.91 Inactive DFGin‑BLBplus DFGAsp-rot-in out-none out-none TYR APEdihe_nniai APEdist_aaaa SX8 Type1 1050 - 1356 0 None Y1194F,Y1230L,Y1234F,Y1235D Hepatocyte growth factor receptor
TYR MET MET_HUMAN 1R0PA 1.8 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-out TYR APEdihe_oiiai APEdist_aaaa KSA Type1 1050 - 1360 0 None Y1194F,Y1234F,Y1235D,L1272L Hepatocyte growth factor receptor
TYR MET MET_HUMAN 5HNIX 1.71 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-none TYR APEdihe_nnnan APEdist_aaaa 63B Type1 1063 - 1356 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 5HNIY 1.71 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-none TYR APEdihe_nnnan APEdist_aaaa 63B Type1 1063 - 1356 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 5HO6A 1.97 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-none TYR APEdihe_nniai APEdist_aaaa 63K Type1 1063 - 1356 0 None Y1194F,Y1234F,Y1235D Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3QTIA 2.0 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-none TYR APEdihe_nniai APEdist_aaaa 3QT Type1 1052 - 1360 0 None Y1194F,Y1234F,Y1235D Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3QTIB 2.0 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-none TYR APEdihe_nniai APEdist_aaaa 3QT Type1 1058 - 1360 0 None Y1194F,Y1234F,Y1235D Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3DKFA 1.8 Inactive DFGin‑BLBplus DFGAsp-rot-in out-none out-none TYR APEdihe_niiai APEdist_aaaa SX8 Type1 1050 - 1360 0 None Y1194F,Y1234F,Y1235D Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3A4PA 2.54 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-out TYR APEdihe_oiiai APEdist_aaaa DFQ Type1 1063 - 1360 0 None Y1194F,Y1234F,Y1235D Hepatocyte growth factor receptor
TYR MET MET_HUMAN 5HOAA 2.14 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-none TYR APEdihe_nniai APEdist_aaaa 63K Type1 1065 - 1356 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 5HORA 2.2 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-none TYR APEdihe_nniai APEdist_aaaa 63K Type1 1064 - 1356 0 None Y1194F,Y1234F,Y1235D,M1250T Hepatocyte growth factor receptor
TYR MET MET_HUMAN 9SXJA 1.315 Inactive DFGin‑BLBplus DFGAsp-rot-in out-none out-none TYR APEdihe_niiai APEdist_aaaa A1JRF, 12P Type1, Allosteric 1057 - 1345 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 9T6KA 1.133 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa A1JT6, 15P, 15P Type1, Allosteric, Allosteric 1054 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3U6HA 2.0 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nnnai APEdist_aaaa 03X Type1.5_Front 1051 - 1351 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3U6IA 2.1 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa 044 Type1.5_Front 1051 - 1351 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 5HLWA 1.97 Inactive DFGin‑BLBtrans DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa 62E Type1 1057 - 1355 0 None Y1230H Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3EFKA 2.2 Inactive DFGin‑None DFGAsp-rot-in out-out none-none TYR APEdihe_nnnai APEdist_aaaa MT4 Type1.5_Front 1054 - 1351 0 None L1272L Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3EFKB 2.2 Inactive DFGin‑None DFGAsp-rot-in out-out none-none TYR APEdihe_nnnai APEdist_aaaa MT4 Type1.5_Front 1054 - 1351 0 None L1272L Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3RHKB 1.94 Inactive DFGout‑BBAminus DFGAsp-rot-out out-none out-in TYR APEdihe_iiiai APEdist_aaaa M97 Type1 1046 - 1344 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8ANSA 2.01 Inactive DFGout‑BBAminus DFGAsp-rot-in out-none in-none TYR APEdihe_nniai APEdist_aaaa MDI Type1.5_Front 1052 - 1346 0 None D1228V Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8VI1A 3.11 Inactive DFGout‑BBAminus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa A1AB1 Type1.5_Front 1053 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8VI1B 3.11 Inactive DFGout‑BBAminus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa A1AB1 Type1.5_Front 1050 - 1345 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8AN8A 2.394 Inactive DFGout‑BBAminus DFGAsp-rot-in out-out in-none TYR APEdihe_nnnai APEdist_aaaa MDI Type1.5_Front 1073 - 1345 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8AN8B 2.394 Inactive DFGout‑BBAminus DFGAsp-rot-in out-out in-none TYR APEdihe_nniai APEdist_aaaa MDI Type1.5_Front 1058 - 1345 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 6SDCA 1.67 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 88Z Type2 1052 - 1346 0 None D1228V Hepatocyte growth factor receptor
TYR MET MET_HUMAN 6SDDA 1.93 Inactive DFGout‑BBAminus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa 353 Type2 1062 - 1344 0 None D1228V Hepatocyte growth factor receptor
TYR MET MET_HUMAN 9T0BA 1.539 Inactive DFGout‑BBAminus DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa A1JSO Type2 1047 - 1343 0 None D1228V Hepatocyte growth factor receptor
TYR MET MET_HUMAN 9T1QA 1.942 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa A1JSR Type2 1054 - 1346 0 None D1228V Hepatocyte growth factor receptor
TYR MET MET_HUMAN 9T3QA 1.629 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-none TYR APEdihe_niiai APEdist_aaaa A1JS8 Type2 1052 - 1346 0 None D1228V Hepatocyte growth factor receptor
TYR MET MET_HUMAN 9C1RA 1.59 Inactive DFGout‑BBAminus DFGAsp-rot-in in-out none-none TYR APEdihe_nnnai APEdist_aaaa A1ATS Type2 1048 - 1348 0 None D1228N Hepatocyte growth factor receptor
TYR MET MET_HUMAN 9T08A 1.462 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-none TYR APEdihe_nniai APEdist_aaaa A1JSO Type2 1059 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 9T0DA 1.196 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-none TYR APEdihe_niiai APEdist_aaaa A1JSR Type2 1059 - 1345 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 9T2VA 1.665 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa A1JS8 Type2 1052 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3LQ8A 2.02 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 88Z Type2 1053 - 1345 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 6SD9A 2.35 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 88Z Type2 1062 - 1345 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 4EEVA 1.8 Inactive DFGout‑BBAminus DFGAsp-rot-in in-out none-none TYR APEdihe_niiai APEdist_aaaa L1X Type2 1045 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 4MXCA 1.632 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa DWF Type2 1052 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 5HTIA 1.66 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 66L Type2 1052 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 7V3SA 1.9 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 5I9 Type2 1053 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3VW8A 2.1 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa DF6 Type2 1024 - 1352 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3CE3A 2.4 Inactive DFGout‑BBAminus DFGAsp-rot-in out-out none-out TYR APEdihe_oiiai APEdist_aaaa 1FN Type2 1054 - 1360 0 None Y1194F,Y1234F,Y1235D,L1272L Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3CTHA 2.3 Inactive DFGout‑BBAminus DFGAsp-rot-in out-out none-out TYR APEdihe_oiiai APEdist_aaaa 319 Type2 1052 - 1360 0 None Y1194F,Y1234F,Y1235D Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3F82A 2.5 Inactive DFGout‑BBAminus DFGAsp-rot-in out-out none-none TYR APEdihe_niiai APEdist_aaaa 353 Type2 1055 - 1360 0 None Y1194F,Y1234F,Y1235D Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3L8VA 2.4 Inactive DFGout‑BBAminus DFGAsp-rot-in in-out none-out TYR APEdihe_oiiai APEdist_aaaa L8V Type2 1054 - 1360 0 None Y1194F,Y1234F,Y1235D Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8OUUA 1.77 Inactive DFGout‑BBAminus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa W49 Type3 1059 - 1346 0 None D1228V Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8OUUB 1.77 Inactive DFGout‑BBAminus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa W49 Type3 1057 - 1346 0 None D1228V Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8OUVA 1.783 Inactive DFGout‑BBAminus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa W3R Type3 1053 - 1346 0 None D1228V Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8OUVB 1.783 Inactive DFGout‑BBAminus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa W3R Type3 1057 - 1346 0 None D1228V Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8OV7A 1.95 Inactive DFGout‑BBAminus DFGAsp-rot-in out-out out-out TYR APEdihe_iioai APEdist_aaaa W3W Type3 1051 - 1346 0 None D1228V Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8OVZA 2.206 Inactive DFGout‑BBAminus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa W3N Type3 1061 - 1346 0 None D1228V Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8OVZB 2.206 Inactive DFGout‑BBAminus DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa W3N Type3 1057 - 1346 0 None D1228V Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8OWGA 2.631 Inactive DFGout‑BBAminus DFGAsp-rot-in out-none out-none TYR APEdihe_nnnai APEdist_aaaa W40 Type3 1060 - 1344 0 None D1228V Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8OWGB 2.631 Inactive DFGout‑BBAminus DFGAsp-rot-in out-none out-in TYR APEdihe_iiiai APEdist_aaaa W40 Type3 1060 - 1343 0 None D1228V Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8OWGC 2.631 Inactive DFGout‑BBAminus DFGAsp-rot-in out-none none-none TYR APEdihe_nniai APEdist_aaaa W40 Type3 1060 - 1343 0 None D1228V Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8OW3A 2.27 Inactive DFGout‑BBAminus DFGAsp-rot-in out-none none-none TYR APEdihe_nniai APEdist_aaaa W40 Type3 1058 - 1345 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3RHKA 1.94 Inactive DFGout‑None DFGAsp-rot-out out-out out-in TYR APEdihe_iiiai APEdist_aaaa M97 Type1 1049 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3EFJA 2.6 Inactive DFGout‑None DFGAsp-rot-in out-out none-none TYR APEdihe_nnnai APEdist_aaaa MT3 Type1.5_Front 1054 - 1351 0 None L1272L Hepatocyte growth factor receptor
TYR MET MET_HUMAN 5DG5A 2.6 Inactive DFGout‑None DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa 5B4 Type2 1050 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 5DG5B 2.6 Inactive DFGout‑None DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa 5B4 Type2 1050 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 7V3RA 1.7 Inactive DFGout‑None DFGAsp-rot-in in-out out-none TYR APEdihe_nniai APEdist_aaaa 5IE Type2 1053 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3CTJA 2.5 Inactive DFGout‑None DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa 320 Type2 1051 - 1360 0 None Y1194F,Y1234F,Y1235D Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3C1XA 2.17 Inactive DFGout‑None DFGAsp-rot-in in-out none-none TYR APEdihe_nniai APEdist_aaaa CKK Type2 1050 - 1360 0 None Y1194F,Y1234F,Y1235D,L1272L Hepatocyte growth factor receptor
TYR MET MET_HUMAN 5T3QA 2.0 Inactive None‑None DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa 75H Type1.5_Front 1050 - 1350 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 2RFNA 2.5 Inactive None‑None DFGAsp-rot-out out-out none-none TYR APEdihe_nnnai APEdist_aaaa AM7 Type1.5_Front 1057 - 1351 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 2RFNB 2.5 Inactive None‑None DFGAsp-rot-out out-out none-none TYR APEdihe_nnnai APEdist_aaaa AM7 Type1.5_Front 1056 - 1351 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3EFJB 2.6 Inactive None‑None DFGAsp-rot-in out-none none-none TYR APEdihe_nnnai APEdist_aaaa MT3 Type1.5_Front 1054 - 1351 0 None L1272L Hepatocyte growth factor receptor
TYR MST1R RON_HUMAN AF-Q04912-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 1072 - 1351 0 None None Macrophage-stimulating protein receptor
TYR MST1R RON_HUMAN AF-Q04912-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 1072 - 1351 0 None None Macrophage-stimulating protein receptor
TYR MST1R RON_HUMAN 3PLSA 2.24 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oioai APEdist_aaaa ANP ATPlike 1060 - 1357 0 None M1254T Macrophage-stimulating protein receptor
TYR MST1R RON_HUMAN 8ZKDA 2.05 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_iooai APEdist_aaaa ANP ATPlike 1060 - 1357 0 None None Macrophage-stimulating protein receptor
TYR MUSK MUSK_HUMAN AF-O15146-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 567 - 866 0 None None Muscle, skeletal receptor tyrosine-protein kinase
TYR MUSK MUSK_HUMAN AF-O15146-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 567 - 866 0 None None Muscle, skeletal receptor tyrosine-protein kinase
TYR NTRK1 NTRK1_HUMAN 5KVTA 2.45 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa YMX Type1 501 - 787 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 6IQNB 2.54 Inactive DFGin‑ABAminus DFGAsp-rot-in out-out none-none TYR APEdihe_nniai APEdist_aaaa AQ6 Type1 502 - 788 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 4YNEA 2.023 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out none-in TYR APEdihe_iiiai APEdist_aaaa 4EK Type1 502 - 793 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 4AOJA 2.75 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in none-in TYR APEdihe_iiiai APEdist_aaaa V4Z Type1 500 - 789 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 4AOJC 2.75 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out none-none TYR APEdihe_niiai APEdist_aaaa V4Z Type1 500 - 789 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 7VKNA 2.7 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa 7GI Type1 502 - 794 0 None G595R High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN AF-P04629-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 502 - 791 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN AF-P04629-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 502 - 791 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 4PMTA 2.1 Inactive DFGin‑None DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa 31Y Type1 501 - 787 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 5I8AA 2.33 Inactive DFGin‑None DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 69C Type1 501 - 787 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 6IQNA 2.54 Inactive DFGin‑None DFGAsp-rot-in in-out none-in TYR APEdihe_iiiai APEdist_aaaa AQ6 Type1 502 - 790 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 7XAFA 3.001 Inactive DFGin‑None DFGAsp-rot-none in-out out-in TYR APEdihe_iiiai APEdist_aaaa FKT Type1 498 - 796 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 6J5LA 2.3 Inactive DFGin‑None DFGAsp-rot-in in-in none-in TYR APEdihe_iiiai APEdist_aaaa B9C Type1 502 - 790 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 6PMEB 3.0 Inactive DFGin‑None DFGAsp-rot-out in-out out-none TYR APEdihe_niiai APEdist_aaaa OOY Type1 499 - 791 0 SEP677 None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 9DAIA 2.864 Inactive DFGin‑None DFGAsp-rot-out in-in none-none TYR APEdihe_nniai APEdist_aaaa STU Type1 501 - 796 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 7VKOA 2.9 Inactive DFGin‑None DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa 7GI Type1 502 - 793 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 4AOJB 2.75 Inactive DFGin‑None DFGAsp-rot-in in-out none-none TYR APEdihe_nniai APEdist_aaaa V4Z Type1 500 - 791 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 6DKGA 2.53 Inactive DFGout‑BBAminus DFGAsp-rot-in in-out none-in TYR APEdihe_iiiai APEdist_aaaa 22L, GO7 Allosteric, Type2 500 - 796 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 6DKIA 2.11 Inactive DFGout‑BBAminus DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa 22L, GOD Allosteric, Type2 500 - 796 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 6D1ZA 1.87 Inactive DFGout‑BBAminus DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa FQD, FQM Allosteric, Type3 483 - 796 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 7VKMA 2.55 Inactive DFGout‑BBAminus DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 502 - 795 0 None G595R High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 4PMPA 1.8 Inactive DFGout‑BBAminus DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa 31W Type1 501 - 787 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 5H3QA 2.1 Inactive DFGout‑BBAminus DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa 7HF Type1 484 - 796 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 4PMMA 2.0 Inactive DFGout‑BBAminus DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa 31V Type2 501 - 787 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 5JFSA 2.07 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa 6K0 Type2 502 - 793 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 5JFVA 1.59 Inactive DFGout‑BBAminus DFGAsp-rot-in out-out none-none TYR APEdihe_nniai APEdist_aaaa 6K1 Type2 502 - 793 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 5JFWA 1.52 Inactive DFGout‑BBAminus DFGAsp-rot-in out-out none-none TYR APEdihe_nniai APEdist_aaaa 6K2 Type2 502 - 793 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 5JFXA 1.63 Inactive DFGout‑BBAminus DFGAsp-rot-in out-in none-none TYR APEdihe_nniai APEdist_aaaa 6K4 Type2 502 - 793 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 6DKWA 2.91 Inactive DFGout‑BBAminus DFGAsp-rot-in out-out none-none TYR APEdihe_nniai APEdist_aaaa GXA Type2 502 - 793 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 6DKWB 2.91 Inactive DFGout‑BBAminus DFGAsp-rot-in in-out none-in TYR APEdihe_iiiai APEdist_aaaa GXA Type2 502 - 793 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 6PL2A 2.59 Inactive DFGout‑BBAminus DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa OOM Type2 499 - 795 0 SEP677 None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 7XBIA 2.16 Inactive DFGout‑BBAminus DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa CVY Type2 497 - 795 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 8J5XA 2.092 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa A4U Type2 500 - 795 0 None G595R High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 6PL4A 2.06 Inactive DFGout‑BBAminus DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa OO7 Type3 485 - 795 0 SEP677 None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 6D20A 1.94 Inactive DFGout‑None DFGAsp-rot-out out-out out-in TYR APEdihe_iiiai APEdist_aaaa FQD, FQG Allosteric, Type3 482 - 796 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 4F0IA 2.302 Inactive DFGout‑None DFGAsp-rot-out out-out out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 501 - 790 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 4F0IB 2.302 Inactive DFGout‑None DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 501 - 794 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 4GT5A 2.398 Inactive DFGout‑None DFGAsp-rot-out in-none out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 498 - 793 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 6D22A 2.46 Inactive DFGout‑None DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 502 - 794 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 6DKBA 2.68 Inactive DFGout‑None DFGAsp-rot-in out-in none-none TYR APEdihe_niiai APEdist_aaaa FKY Type1 501 - 796 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 5KMOA 2.67 Inactive DFGout‑None DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa 6UM Type1 500 - 796 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 4PMSA 2.8 Inactive DFGout‑None DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa 31X Type1.5_Back 501 - 787 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 8J5WA 2.28 Inactive DFGout‑None DFGAsp-rot-none in-out out-in TYR APEdihe_iiiai APEdist_aaaa A4U Type2 485 - 795 0 None F589L High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 8J61A 3.051 Inactive DFGout‑None DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa A0X Type2 499 - 795 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 8J63A 3.001 Inactive DFGout‑None DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa A6X Type2 500 - 796 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 5WR7A 2.76 Inactive DFGout‑None DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa RCH Type2 489 - 792 0 SEP677 None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 6PL1A 2.03 Inactive DFGout‑None DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa OOJ Type2 500 - 795 0 SEP677 None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 6PL3A 3.0 Inactive DFGout‑None DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa OOD Type2 500 - 795 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 6PMAA 2.53 Inactive DFGout‑None DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa OQS Type2 500 - 795 0 SEP677 None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 6PMBA 2.81 Inactive DFGout‑None DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa OQM Type2 500 - 795 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 6PMCA 2.19 Inactive DFGout‑None DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa OQJ Type2 500 - 795 0 SEP677 None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 6NSPA 2.31 Inactive DFGout‑None DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa L0P Type3 500 - 795 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 6NPTA 2.19 Inactive DFGout‑None DFGAsp-rot-out out-out out-in TYR APEdihe_iiiai APEdist_aaaa KWY Type3 491 - 795 0 SEP677 None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 6NSSA 1.97 Inactive DFGout‑None DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa L0M Type3 485 - 795 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 6D1YA 1.93 Inactive DFGout‑None DFGAsp-rot-out out-out out-in TYR APEdihe_iiiai APEdist_aaaa FQJ Type3 481 - 796 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 5KMIA 1.87 Inactive DFGout‑None DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa 6UE Type3 486 - 796 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 5KMJA 2.04 Inactive DFGout‑None DFGAsp-rot-out in-in out-in TYR APEdihe_iiiai APEdist_aaaa 6UF Type3 486 - 795 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 5KMKA 2.24 Inactive DFGout‑None DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa 6UG Type3 484 - 796 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 5KMMA 2.12 Inactive DFGout‑None DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa 6UJ Type3 484 - 796 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 5KMLA 2.01 Inactive DFGout‑None DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa 6UH Type3 474 - 796 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 5KMNA 2.14 Inactive DFGout‑None DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa 6UK Type3 474 - 796 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 4YPSA 2.101 Inactive None‑None DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa 4F6 Type1 502 - 790 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 6PMEA 3.0 Inactive None‑None DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa OOY Type1 500 - 788 0 SEP677 None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 6PMEC 3.0 Inactive None‑None DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa OOY Type1 500 - 790 0 SEP677 None High affinity nerve growth factor receptor
TYR NTRK2 NTRK2_HUMAN AF-Q16620-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 530 - 817 0 None None BDNF/NT-3 growth factors receptor
TYR NTRK2 NTRK2_HUMAN AF-Q16620-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 530 - 817 0 None None BDNF/NT-3 growth factors receptor
TYR NTRK2 NTRK2_HUMAN 4AT3A 1.77 Inactive DFGin‑None DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa LTI Type1 527 - 822 0 None None BDNF/NT-3 growth factors receptor
TYR NTRK2 NTRK2_HUMAN 4AT4A 2.36 Inactive DFGout‑BBAminus DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa T6E Type2 527 - 822 0 None None BDNF/NT-3 growth factors receptor
TYR NTRK2 NTRK2_HUMAN 4ASZA 1.7 Inactive DFGout‑None DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 527 - 822 0 None None BDNF/NT-3 growth factors receptor
TYR NTRK2 NTRK2_HUMAN 4AT5A 1.71 Inactive DFGout‑None DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa MUJ Type2 527 - 822 0 None None BDNF/NT-3 growth factors receptor
TYR NTRK3 NTRK3_HUMAN AF-Q16288-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 530 - 834 0 None None NT-3 growth factor receptor
TYR NTRK3 NTRK3_HUMAN AF-Q16288-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 530 - 834 0 None None NT-3 growth factor receptor
TYR NTRK3 NTRK3_HUMAN 3V5QA 2.2 Inactive DFGout‑BBAminus DFGAsp-rot-in out-out none-in TYR APEdihe_iiiai APEdist_aaaa 0F4 Type2 530 - 832 0 None None NT-3 growth factor receptor
TYR NTRK3 NTRK3_HUMAN 3V5QB 2.2 Inactive DFGout‑BBAminus DFGAsp-rot-in out-out none-in TYR APEdihe_iiiai APEdist_aaaa 0F4 Type2 530 - 832 0 None None NT-3 growth factor receptor
TYR NTRK3 NTRK3_HUMAN 6KZCA 2.0 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa DZC Type2 528 - 837 0 None None NT-3 growth factor receptor
TYR NTRK3 NTRK3_HUMAN 6KZDA 1.708 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa DZ6 Type2 528 - 837 0 None None NT-3 growth factor receptor
TYR NTRK3 NTRK3_HUMAN 4YMJA 2.0 Inactive DFGout‑None DFGAsp-rot-in out-out none-in TYR APEdihe_iiiai APEdist_aaaa 4EJ Type1 530 - 831 0 SEP706 None NT-3 growth factor receptor
TYR NTRK3 NTRK3_HUMAN 4YMJB 2.0 Inactive DFGout‑None DFGAsp-rot-in out-none out-in TYR APEdihe_iiiai APEdist_aaaa 4EJ Type1 530 - 834 0 SEP706 None NT-3 growth factor receptor
TYR PDGFRA PGFRA_HUMAN AF-P16234-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 585 - 960 0 None None Platelet-derived growth factor receptor alpha
TYR PDGFRA PGFRA_HUMAN AF-P16234-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 585 - 960 0 None None Platelet-derived growth factor receptor alpha
TYR PDGFRA PGFRA_HUMAN 8PQHA 2.5 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 9JI Type1 555 - 971 0 None T674I Platelet-derived growth factor receptor alpha
TYR PDGFRA PGFRA_HUMAN 8PQIA 2.6 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 9OO Type1 567 - 969 0 None T674I Platelet-derived growth factor receptor alpha
TYR PDGFRA PGFRA_HUMAN 6JOIA 3.1 Inactive DFGin‑BLAplus DFGAsp-rot-out in-out none-in TYR APEdihe_iiiai APEdist_aaaa 6T2 Type1 569 - 973 0 None T674I Platelet-derived growth factor receptor alpha
TYR PDGFRA A0A0B4J203_HUMAN 8XRRA 2.57 Inactive DFGin‑BLBminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1LV8 Type1 338 - 730 0 None None receptor protein-tyrosine kinase
TYR PDGFRA PGFRA_HUMAN 9GZHA 2.2 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa A1IRC Type2 583 - 958 0 None T674I Platelet-derived growth factor receptor alpha
TYR PDGFRA PGFRA_HUMAN 5GRNA 1.77 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 748 Type2 583 - 958 0 None None Platelet-derived growth factor receptor alpha
TYR PDGFRA PGFRA_HUMAN 6JOLA 1.9 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa STI Type2 583 - 957 0 None None Platelet-derived growth factor receptor alpha
TYR PDGFRA PGFRA_HUMAN 8PQKA 2.0 Inactive DFGout‑None DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 554 - 973 0 None T674I Platelet-derived growth factor receptor alpha
TYR PDGFRA PGFRA_HUMAN 6A32A 1.87 Inactive DFGout‑None DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 554 - 973 0 None T674I Platelet-derived growth factor receptor alpha
TYR PDGFRA PGFRA_HUMAN 8PQJA 1.82 Inactive DFGout‑None DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 553 - 973 0 None None Platelet-derived growth factor receptor alpha
TYR PDGFRA PGFRA_HUMAN 5K5XA 2.168 Inactive DFGout‑None DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 554 - 973 0 None None Platelet-derived growth factor receptor alpha
TYR PDGFRA PGFRA_HUMAN 6JOKA 3.8 Inactive DFGout‑None DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa B49 Type1 556 - 973 0 None None Platelet-derived growth factor receptor alpha
TYR PDGFRA PGFRA_HUMAN 6JOJA 2.6 Inactive None‑None DFGAsp-rot-out in-in out-in TYR APEdihe_iiiai APEdist_aaaa 6T2 Type1 554 - 973 0 None None Platelet-derived growth factor receptor alpha
TYR PDGFRB PGFRB_HUMAN AF-P09619-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 592 - 968 0 None None Platelet-derived growth factor receptor beta
TYR PDGFRB PGFRB_HUMAN AF-P09619-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 592 - 968 0 None None Platelet-derived growth factor receptor beta
TYR PTK2 FAK1_HUMAN 9SDIA 2.53 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out none-none TYR APEdihe_nniai APEdist_aaaa A1JNJ Type1 414 - 686 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 3PXKA 1.79 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa PXK Type1 415 - 687 0 None P410G Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 3PXKB 1.79 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa PXK Type1 414 - 687 0 None P410G Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 6YT6A 1.537 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa PKE Type1 414 - 686 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 6YT6B 1.537 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in none-none TYR APEdihe_niiai APEdist_aaaa PKE Type1 414 - 686 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 6YVSA 1.81 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out in-none TYR APEdihe_niiai APEdist_aaaa PVT Type1 414 - 686 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 6YVYA 1.918 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out in-in TYR APEdihe_iiiai APEdist_aaaa P1E Type1 412 - 686 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN AF-Q05397-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 414 - 686 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN AF-Q05397-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 414 - 686 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 4GU9B 2.4 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in out-none TYR APEdihe_nniai APEdist_aaaa 4GU Type1 415 - 683 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 4K8AA 2.91 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out none-none TYR APEdihe_nniai APEdist_aaaa K8A Type1 414 - 683 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 4K8AB 2.91 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out out-none TYR APEdihe_nniai APEdist_aaaa K8A Type1 414 - 684 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 4KABB 2.71 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in out-none TYR APEdihe_nniai APEdist_aaaa 4KA Type1 414 - 684 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 2ETMA 2.3 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out out-none TYR APEdihe_niiai APEdist_aaaa 7PY Type1 415 - 686 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 2ETMB 2.3 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in out-out TYR APEdihe_nnoai APEdist_aaaa 7PY Type1 413 - 689 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 6YVYB 1.918 None DFGin‑BLAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa P1E Type1 415 - 686 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 2IJMB 2.187 Inactive DFGin‑BLBminus DFGAsp-rot-in in-out none-out TYR APEdihe_nnoai APEdist_aaaa ADP ATPlike 414 - 689 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 2IJMA 2.187 Inactive DFGin‑None DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa ATP ATPlike 414 - 688 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 7PI4DDD 2.24 Inactive DFGin‑None DFGAsp-rot-in in-in out-none TYR APEdihe_niiai APEdist_aaaa No_ligand No_ligand 415 - 687 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 9SDIB 2.53 Inactive DFGin‑None DFGAsp-rot-out in-out none-none TYR APEdihe_nniai APEdist_aaaa No_ligand No_ligand 414 - 685 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 3BZ3A 2.2 Inactive DFGin‑None DFGAsp-rot-in in-in out-none TYR APEdihe_nniai APEdist_aaaa YAM Type1 414 - 689 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 4GU9A 2.4 Inactive DFGin‑None DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa 4GU Type1 414 - 685 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 4KABA 2.71 Inactive DFGin‑None DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa 4KA Type1 412 - 686 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 6I8ZA 1.99 Inactive DFGin‑None DFGAsp-rot-in in-in out-none TYR APEdihe_nniai APEdist_aaaa H82 Type1 414 - 688 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 4I4EA 1.55 Inactive DFGin‑None DFGAsp-rot-in in-out none-none TYR APEdihe_nniai APEdist_aaaa 1BQ Type1 414 - 686 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 4GU6A 1.95 Inactive DFGin‑None DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 10N Type1 414 - 686 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 4GU6B 1.95 Inactive DFGin‑None DFGAsp-rot-in in-in out-none TYR APEdihe_nniai APEdist_aaaa 10N Type1 415 - 686 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 6YOJA 1.361 Inactive DFGin‑None DFGAsp-rot-in in-in out-none TYR APEdihe_nniai APEdist_aaaa P4N Type1 414 - 686 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 6YQ1A 1.784 Inactive DFGin‑None DFGAsp-rot-in in-in out-none TYR APEdihe_niiai APEdist_aaaa P7N Type1 415 - 686 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 6YQ1B 1.784 Inactive DFGin‑None DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa P7N Type1 411 - 686 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 6YQ1C 1.784 Inactive DFGin‑None DFGAsp-rot-in in-in out-none TYR APEdihe_niiai APEdist_aaaa P7N Type1 412 - 686 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 6YQ1D 1.784 Inactive DFGin‑None DFGAsp-rot-in in-in out-none TYR APEdihe_nniai APEdist_aaaa P7N Type1 415 - 686 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 6YR9A 1.925 Inactive DFGin‑None DFGAsp-rot-in in-in out-none TYR APEdihe_nniai APEdist_aaaa P9K Type1 415 - 686 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 6YR9B 1.925 Inactive DFGin‑None DFGAsp-rot-in in-in out-none TYR APEdihe_niiai APEdist_aaaa P9K Type1 414 - 684 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 6YR9C 1.925 Inactive DFGin‑None DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa P9K Type1 414 - 686 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 6YR9D 1.925 Inactive DFGin‑None DFGAsp-rot-in in-in out-none TYR APEdihe_nniai APEdist_aaaa P9K Type1 412 - 685 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 6YVSB 1.81 Inactive DFGin‑None DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa PVT Type1 415 - 686 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 6YVSD 1.81 Inactive DFGin‑None DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa PVT Type1 412 - 686 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 6YVYC 1.918 Inactive DFGin‑None DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa P1E Type1 411 - 686 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 6YVYD 1.918 Inactive DFGin‑None DFGAsp-rot-out in-out none-none TYR APEdihe_niiai APEdist_aaaa P1E Type1 415 - 686 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 6YXVA 2.298 Inactive DFGin‑None DFGAsp-rot-in in-in out-none TYR APEdihe_nniai APEdist_aaaa Q2H Type1 414 - 686 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 6YXVB 2.298 Inactive DFGin‑None DFGAsp-rot-in in-in out-none TYR APEdihe_nniai APEdist_aaaa Q2H Type1 415 - 686 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 6YXVC 2.298 Inactive DFGin‑None DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa Q2H Type1 414 - 686 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 6YXVD 2.298 Inactive DFGin‑None DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa Q2H Type1 415 - 686 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 4EBWA 2.65 Inactive DFGinter‑None DFGAsp-rot-out in-in none-none TYR APEdihe_niiai APEdist_aaaa 0PF Type1 411 - 686 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 4KAOA 2.39 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa KAO Type2 415 - 686 0 None P410G Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 4KAOB 2.39 Inactive DFGout‑BBAminus DFGAsp-rot-in in-out none-none TYR APEdihe_nniai APEdist_aaaa KAO Type2 414 - 686 0 None P410G Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 4EBVA 1.67 Inactive DFGout‑None DFGAsp-rot-out in-in none-none TYR APEdihe_niiai APEdist_aaaa 0O7 Type1 411 - 686 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 4K9YA 2.0 Inactive DFGout‑None DFGAsp-rot-in in-in out-out TYR APEdihe_oiiai APEdist_aaaa K9Y Type2 415 - 685 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 4I4FA 1.75 Inactive DFGout‑None DFGAsp-rot-out out-out none-none TYR APEdihe_niiai APEdist_aaaa 1BR Type3 415 - 686 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 1MP8A 1.6 Inactive None‑None DFGAsp-rot-out in-in none-none TYR APEdihe_nniai APEdist_aaaa ADP ATPlike 414 - 686 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 4Q9SA 2.07 Inactive None‑None DFGAsp-rot-out in-in none-none TYR APEdihe_nniai APEdist_aaaa 30G Type1 414 - 686 0 None None Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 6YVSC 1.81 Inactive None‑None DFGAsp-rot-in in-out none-none TYR APEdihe_nniai APEdist_aaaa PVT Type1 414 - 686 0 None None Focal adhesion kinase 1
TYR PTK2B FAK2_HUMAN AF-Q14289-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 417 - 689 0 None None Protein-tyrosine kinase 2-beta
TYR PTK2B FAK2_HUMAN AF-Q14289-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 417 - 689 0 None None Protein-tyrosine kinase 2-beta
TYR PTK2B FAK2_HUMAN 3FZOA 2.2 Inactive DFGin‑None DFGAsp-rot-out in-out out-none TYR APEdihe_nniai APEdist_aaaa No_ligand No_ligand 420 - 691 0 None None Protein-tyrosine kinase 2-beta
TYR PTK2B FAK2_HUMAN 8YGXA 2.0 Inactive DFGin‑None DFGAsp-rot-out in-out none-none TYR APEdihe_nniai APEdist_aaaa No_ligand No_ligand 420 - 691 0 None None Protein-tyrosine kinase 2-beta
TYR PTK2B FAK2_HUMAN 3CC6A 1.6 Inactive DFGin‑None DFGAsp-rot-out in-in out-out TYR APEdihe_oiiai APEdist_aaaa No_ligand No_ligand 415 - 692 0 None None Protein-tyrosine kinase 2-beta
TYR PTK2B FAK2_HUMAN 8XOXA 1.9 Inactive DFGin‑None DFGAsp-rot-out in-out none-none TYR APEdihe_nniai APEdist_aaaa YAM Type1 417 - 692 0 None None Protein-tyrosine kinase 2-beta
TYR PTK2B FAK2_HUMAN 5TOBA 2.117 Inactive DFGin‑None DFGAsp-rot-out in-none none-none TYR APEdihe_nnnai APEdist_aaaa YAM Type1 420 - 690 0 None None Protein-tyrosine kinase 2-beta
TYR PTK2B FAK2_HUMAN 3FZSA 1.75 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa B96 Type2 420 - 690 0 None None Protein-tyrosine kinase 2-beta
TYR PTK2B FAK2_HUMAN 4H1MA 1.99 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa 0YJ Type2 420 - 690 0 None None Protein-tyrosine kinase 2-beta
TYR PTK2B FAK2_HUMAN 3FZPA 2.1 Inactive DFGout‑None DFGAsp-rot-out in-out none-in TYR APEdihe_iiiai APEdist_aaaa AGS ATPlike 419 - 692 0 None None Protein-tyrosine kinase 2-beta
TYR PTK2B FAK2_HUMAN 3ET7A 2.7 Inactive DFGout‑None DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 349 Type1 419 - 691 0 None None Protein-tyrosine kinase 2-beta
TYR PTK2B FAK2_HUMAN 3FZRA 2.7 Inactive DFGout‑None DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 3JZ Type1 419 - 691 0 None None Protein-tyrosine kinase 2-beta
TYR PTK2B FAK2_HUMAN 5TO8A 1.985 Inactive DFGout‑None DFGAsp-rot-out in-none out-none TYR APEdihe_nnnan APEdist_aaaa 7FM Type1 420 - 691 0 None None Protein-tyrosine kinase 2-beta
TYR PTK2B FAK2_HUMAN 3FZTA 1.95 Inactive DFGout‑None DFGAsp-rot-in in-in out-none TYR APEdihe_nniai APEdist_aaaa 4JZ Type2 420 - 690 0 None None Protein-tyrosine kinase 2-beta
TYR PTK2B FAK2_HUMAN 4H1JA 2.0 Inactive DFGout‑None DFGAsp-rot-in in-in out-out TYR APEdihe_oiiai APEdist_aaaa 0YH Type2 419 - 690 0 None None Protein-tyrosine kinase 2-beta
TYR PTK2B FAK2_HUMAN 3H3CA 2.0 Inactive None‑None DFGAsp-rot-out in-out none-out TYR APEdihe_oiiai APEdist_aaaa P1E Type1 416 - 692 0 None None Protein-tyrosine kinase 2-beta
TYR PTK6 PTK6_HUMAN AF-Q13882-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 183 - 451 0 None None Protein-tyrosine kinase 6
TYR PTK6 PTK6_HUMAN AF-Q13882-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 183 - 451 0 None None Protein-tyrosine kinase 6
TYR PTK6 PTK6_HUMAN 5D7VA 2.33 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oooai APEdist_aaaa No_ligand No_ligand 185 - 446 0 None C433T Protein-tyrosine kinase 6
TYR PTK6 PTK6_HUMAN 5D7VB 2.33 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oooai APEdist_aaaa No_ligand No_ligand 185 - 446 0 None C433T Protein-tyrosine kinase 6
TYR PTK6 PTK6_HUMAN 5D7VC 2.33 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oooai APEdist_aaaa No_ligand No_ligand 185 - 446 0 None C433T Protein-tyrosine kinase 6
TYR PTK6 PTK6_HUMAN 5D7VD 2.33 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oooai APEdist_aaaa No_ligand No_ligand 185 - 446 0 None C433T Protein-tyrosine kinase 6
TYR PTK6 PTK6_HUMAN 6CZ2A 2.5 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oioai APEdist_aaaa No_ligand No_ligand 182 - 443 0 PTR342 None Protein-tyrosine kinase 6
TYR PTK6 PTK6_HUMAN 5H2UA 2.24 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oooai APEdist_aaaa 1N1 Type1 185 - 446 0 None C433T Protein-tyrosine kinase 6
TYR PTK6 PTK6_HUMAN 5H2UB 2.24 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oooai APEdist_aaaa 1N1 Type1 185 - 446 0 None C433T Protein-tyrosine kinase 6
TYR PTK6 PTK6_HUMAN 5H2UC 2.24 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oooai APEdist_aaaa 1N1 Type1 185 - 446 0 None C433T Protein-tyrosine kinase 6
TYR PTK6 PTK6_HUMAN 5H2UD 2.24 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oooai APEdist_aaaa 1N1 Type1 185 - 446 0 None C433T Protein-tyrosine kinase 6
TYR PTK6 PTK6_HUMAN 5DA3A 1.7 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oooai APEdist_aaaa 58V Type1 185 - 446 0 None C433T Protein-tyrosine kinase 6
TYR PTK6 PTK6_HUMAN 6CZ3A 1.8 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oioai APEdist_aaaa FLJ Type1 182 - 443 0 None None Protein-tyrosine kinase 6
TYR PTK6 PTK6_HUMAN 6CZ4A 1.5 Inactive DFGout‑BBAminus DFGAsp-rot-in out-out out-none TYR APEdihe_nnnai APEdist_aaaa FKY Type2 183 - 443 0 None None Protein-tyrosine kinase 6
TYR PTK7 PTK7_HUMAN 6VG3A 1.95 Pseudo DFGout‑BBAminus DFGAsp-rot-none in-in out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 788 - 1064 0 None None Inactive tyrosine-protein kinase 7
TYR PTK7 PTK7_HUMAN 6VG3B 1.95 Pseudo DFGout‑BBAminus DFGAsp-rot-none in-in out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 788 - 1066 0 None None Inactive tyrosine-protein kinase 7
TYR PTK7 PTK7_HUMAN 6VG3C 1.95 Pseudo DFGout‑BBAminus DFGAsp-rot-none in-in out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 789 - 1063 0 None None Inactive tyrosine-protein kinase 7
TYR RET RET_HUMAN 2IVTA 2.6 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa AMP ATPlike 703 - 1012 0 PTR905 None Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 6NE7A 1.99 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa AMP ATPlike 705 - 1013 0 PTR900,PTR905 G810A Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN AF-P07949-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 716 - 1015 0 None None Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN AF-P07949-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 716 - 1015 0 None None Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 5AMNA 2.57 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa DTQ Type1 705 - 1010 0 PTR900,PTR905 None Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 6FEKA 2.3 Inactive DFGin‑BLAminus DFGAsp-rot-none in-none in-out TYR APEdihe_oiiai APEdist_aaaa ADN Type1 705 - 1010 0 PTR900,PTR905 S904F Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 6I82A 2.05 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa H6W Type1 705 - 1012 0 PTR928 V804M Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 6I82B 2.05 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa H6W Type1 714 - 1012 0 PTR928 V804M Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 6I83A 1.88 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa H72 Type1 705 - 1013 0 PTR905 V804M Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 6VHGA 2.303 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa QX1 Type1 707 - 1012 0 PTR905,PTR928 None Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 2IVSA 2.0 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa ACK Type1 713 - 1012 0 None None Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 2IVSB 2.0 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa ACK Type1 703 - 1012 0 None None Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 2IVUA 2.5 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa ZD6 Type1 703 - 1012 0 PTR905 None Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 2X2KA 2.6 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa X2K Type1 703 - 1013 0 PTR905 None Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 2X2LA 2.0 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa X2L Type1 703 - 1010 0 PTR905 None Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 2X2MA 2.5 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa X2M Type1 703 - 1013 0 PTR905 None Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 2X2MB 2.5 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa X2M Type1 703 - 1011 0 PTR905 None Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 4CKJA 1.65 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa ADN Type1 705 - 1013 0 PTR905 None Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 6NJAA 1.92 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa ADE Type1 705 - 1013 0 PTR900,PTR905 None Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 7DU9A 2.31 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa Q4J Type1 714 - 1011 0 None None Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 7DU9B 2.31 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa Q4J Type1 705 - 1012 0 None None Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 7JU5A 1.9 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa Q4J Type1 705 - 1013 0 None None Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 7JU5B 1.9 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa Q4J Type1 710 - 1012 0 None None Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 7JU6A 2.06 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa Q6G Type1 713 - 1012 0 None None Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 7NZNA 2.39 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa VJH Type1 705 - 1013 0 PTR900,PTR905 None Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 2IVVA 2.25 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa PP1 Type1 703 - 1011 0 PTR905 None Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 5FM2A 3.3 Inactive DFGin‑BLAminus DFGAsp-rot-none in-in in-out TYR APEdihe_oiiai APEdist_aaaa PP1 Type1 710 - 1011 0 PTR809,PTR905,SEP909,PTR928 None Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 5FM3A 2.95 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa PP1 Type1 707 - 1011 0 PTR809,PTR905,SEP909,PTR928 None Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 4CKIA 2.116 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa ADN Type1 705 - 1013 0 PTR900,PTR905 M918T Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 6NECA 1.87 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa XIN Type1.5_Back 713 - 1012 0 None None Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 6NECC 1.87 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa XIN Type1.5_Back 705 - 1012 0 None None Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 7DUAA 1.64 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa HJ0 Type1.5_Back 712 - 1011 0 None None Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 7DUAB 1.64 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa HJ0 Type1.5_Back 705 - 1012 0 None None Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 7RUNA 3.51 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa 7QU Type1.5_Back 705 - 1012 0 PTR809,PTR905,SEP909,PTR928 None Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 7RUNB 3.51 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oiiai APEdist_aaaa 7QU Type1.5_Back 706 - 1012 0 PTR809,PTR905,SEP909,PTR928 None Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 7DU8A 2.75 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa Q6G Type1.5_Front 714 - 1012 0 None None Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 7DU8B 2.75 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa Q6G Type1.5_Front 705 - 1012 0 None None Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 7JU6B 2.06 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa Q6G Type1.5_Front 705 - 1012 0 None None Proto-oncogene tyrosine-protein kinase receptor Ret
TYR ROR1 ROR1_HUMAN 6TU9A 1.94 Pseudo None‑None DFGAsp-rot-in in-in out-in TYR APEdihe_iiiai APEdist_aaaa 0LI Type1 460 - 749 0 None None Inactive tyrosine-protein kinase transmembrane receptor ROR1
TYR ROR1 ROR1_HUMAN 6TU9B 1.94 Pseudo None‑None DFGAsp-rot-in in-in none-in TYR APEdihe_iiiai APEdist_aaaa 0LI Type1 465 - 750 0 None None Inactive tyrosine-protein kinase transmembrane receptor ROR1
TYR ROR2 ROR2_HUMAN 3ZZWA 2.9 Pseudo DFGinter‑None DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 466 - 750 0 None None Tyrosine-protein kinase transmembrane receptor ROR2
TYR ROR2 ROR2_HUMAN 4GT4A 2.406 Pseudo DFGinter‑None DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 464 - 751 0 None None Tyrosine-protein kinase transmembrane receptor ROR2
TYR ROR2 ROR2_HUMAN 4GT4B 2.406 Pseudo DFGinter‑None DFGAsp-rot-none in-in out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 464 - 752 0 None None Tyrosine-protein kinase transmembrane receptor ROR2
TYR ROR2 ROR2_HUMAN 3ZZWB 2.9 Pseudo DFGout‑None DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 466 - 750 0 None None Tyrosine-protein kinase transmembrane receptor ROR2
TYR ROS1 ROS1_HUMAN 3ZBFA 2.2 Inactive DFGin‑ABAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa VGH Type1 1934 - 2230 0 None None Proto-oncogene tyrosine-protein kinase ROS
TYR ROS1 ROS1_HUMAN 4UXLA 2.4 Inactive DFGin‑ABAminus DFGAsp-rot-in in-out in-out TYR APEdihe_ooiai APEdist_aaaa 5P8 Type1 1934 - 2230 0 None None Proto-oncogene tyrosine-protein kinase ROS
TYR ROS1 ROS1_HUMAN AF-P08922-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 1937 - 2225 0 None None Proto-oncogene tyrosine-protein kinase ROS
TYR ROS1 ROS1_HUMAN AF-P08922-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 1937 - 2225 0 None None Proto-oncogene tyrosine-protein kinase ROS
TYR ROS1 ROS1_HUMAN 7Z5WA 2.254 Inactive DFGin‑None DFGAsp-rot-out in-out none-none TYR APEdihe_nniai APEdist_aaaa IDW Type1 1937 - 2225 0 None None Proto-oncogene tyrosine-protein kinase ROS
TYR ROS1 ROS1_HUMAN 7Z5WB 2.254 Inactive DFGin‑None DFGAsp-rot-in in-out none-none TYR APEdihe_nniai APEdist_aaaa IDW Type1 1937 - 2226 0 None None Proto-oncogene tyrosine-protein kinase ROS
TYR ROS1 ROS1_HUMAN 7Z5XA 2.035 Inactive DFGin‑None DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa AWJ Type1 1937 - 2225 0 None None Proto-oncogene tyrosine-protein kinase ROS
TYR ROS1 ROS1_HUMAN 7Z5XB 2.035 Inactive DFGin‑None DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa AWJ Type1 1937 - 2226 0 None None Proto-oncogene tyrosine-protein kinase ROS
TYR ROS1 ROS1_HUMAN 9QEKA 2.205 Inactive DFGin‑None DFGAsp-rot-in in-out none-none TYR APEdihe_niiai APEdist_aaaa A1I6Z Type1 1934 - 2229 0 None G2032R Proto-oncogene tyrosine-protein kinase ROS
TYR RYK RYK_HUMAN 6TUAA 2.38 Inactive DFGin‑None DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 298 - 607 0 None None Tyrosine-protein kinase RYK
TYR SRC SRC_HUMAN AF-P12931-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 262 - 529 0 None None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN AF-P12931-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 262 - 529 0 None None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 1YI6A 2.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 261 - 536 0 PTR338,PTR419 None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 1YI6B 2.0 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 261 - 536 0 PTR338,PTR419 None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 9NS0A 999.0 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 251 - 536 0 PTR419 None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 9NS1A 999.0 Inactive DFGin‑BLAminus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa No_ligand No_ligand 251 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 4MXYA 2.582 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-none TYR APEdihe_nniai APEdist_aaaa DB8 Type1 260 - 536 0 None M317L,T341M Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 4MXYB 2.582 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-none TYR APEdihe_nniai APEdist_aaaa DB8 Type1 261 - 536 0 None M317L,T341M Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 4MXZA 2.582 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-none TYR APEdihe_nniai APEdist_aaaa DB8 Type1 260 - 536 0 None M317L,T341M Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 4MXZB 2.582 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-none TYR APEdihe_nniai APEdist_aaaa DB8 Type1 261 - 536 0 None M317L,T341M Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 4MXXA 2.6 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-none TYR APEdihe_nniai APEdist_aaaa DB8 Type1 260 - 536 0 None A406T Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 6E6EA 2.15 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_ioiai APEdist_aaaa HVY Type1 261 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 6E6EC 2.15 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa HVY Type1 261 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 6E6ED 2.15 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa HVY Type1 261 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 6E6EF 2.15 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa HVY Type1 261 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 6E6EH 2.15 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa HVY Type1 261 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 2BDFA 2.1 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_nniai APEdist_aaaa 24A Type1 260 - 531 0 None None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 2BDFB 2.1 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa 24A Type1 258 - 531 0 None None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 2BDJA 2.5 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_nniai APEdist_aaaa HET Type1 260 - 524 0 None None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 8JF3A 2.846 Inactive DFGin‑BLAminus DFGAsp-rot-out none-none in-none TYR APEdihe_nnnai APEdist_aaaa C0N Type1 260 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 4MXOA 2.105 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa DB8 Type1 260 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 4MXOB 2.105 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa DB8 Type1 261 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 6ATEA 2.402 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa 6H3 Type1 260 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 1Y57A 1.91 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa MPZ Type1 86 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 6E6EB 2.15 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa HVY Type1.5_Back 261 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 6E6EE 2.15 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_ooiai APEdist_aaaa HVY Type1.5_Back 261 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 6E6EG 2.15 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-none TYR APEdihe_nniai APEdist_aaaa HVY Type1.5_Back 261 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 1FMKA 1.5 Inactive DFGin‑BLBminus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa No_ligand No_ligand 86 - 536 0 PTR530 None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 2SRCA 1.5 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa ANP ATPlike 87 - 536 0 PTR530 None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 9IRLA 2.031 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa A1L20 Allosteric 86 - 536 0 PTR530 None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 8JN8A 1.902 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa JA6 Allosteric 86 - 536 0 PTR530 None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 8JN9A 2.724 Inactive DFGin‑BLBplus DFGAsp-rot-out out-none out-out TYR APEdihe_oiiai APEdist_aaaa UJ0 Allosteric 86 - 536 0 PTR530 None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 2H8HA 2.2 Inactive DFGin‑BLBplus DFGAsp-rot-in out-out out-out TYR APEdihe_oiiai APEdist_aaaa H8H Type1 88 - 532 0 PTR530 None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 4K11A 2.3 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa 0J9 Type1 87 - 534 0 PTR530 T341G Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 1KSWA 2.8 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-out TYR APEdihe_oiiai APEdist_aaaa NBS Type1 87 - 536 0 PTR530 T341G Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 7NG7A 1.5 Inactive DFGin‑BLBplus DFGAsp-rot-out out-out out-none TYR APEdihe_nniai APEdist_aaaa UCW Type1.5_Back 260 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 8HAQA 2.27 Inactive DFGin‑None DFGAsp-rot-in none-none none-none TYR APEdihe_nnnai APEdist_aaaa L1N Type1 260 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 8JF3B 2.846 Inactive DFGin‑None DFGAsp-rot-in none-none none-none TYR APEdihe_nnnai APEdist_aaaa C0N Type1 261 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 1YOMB 2.9 Inactive DFGin‑None DFGAsp-rot-out in-none none-out TYR APEdihe_nnoai APEdist_aaaa P01 Type1 258 - 536 0 None S345N,A370S,Y419W Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 4MXXB 2.6 Inactive DFGinter‑BABtrans DFGAsp-rot-out out-out none-none TYR APEdihe_nniai APEdist_aaaa DB8 Type1 261 - 536 0 None A406T Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 7OTEA 2.49 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nniai APEdist_aaaa 0LI Type2 261 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 7OTEB 2.49 Inactive DFGout‑BBAminus DFGAsp-rot-in in-out none-none TYR APEdihe_nniai APEdist_aaaa 0LI Type2 261 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 1YOJA 1.95 Inactive None‑None DFGAsp-rot-none none-none none-none TYR APEdihe_nnnai APEdist_aaaa No_ligand No_ligand 264 - 536 0 None S345N,A370S,Y419W Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 1YOJB 1.95 Inactive None‑None DFGAsp-rot-out none-none none-none TYR APEdihe_nnnai APEdist_aaaa No_ligand No_ligand 272 - 536 0 None S345N,A370S,Y419W Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 1YOLA 2.3 Inactive None‑None DFGAsp-rot-out in-none none-none TYR APEdihe_nnnai APEdist_aaaa S03 Type1 259 - 536 0 None S345N,A370S Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 1YOLB 2.3 Inactive None‑None DFGAsp-rot-out in-out none-none TYR APEdihe_nnnai APEdist_aaaa S03 Type1 262 - 536 0 None S345N,A370S Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 8HAQB 2.27 Inactive None‑None DFGAsp-rot-in none-none none-none TYR APEdihe_nnnai APEdist_aaaa L1N Type1 260 - 535 0 None None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 1YOMA 2.9 Inactive None‑None DFGAsp-rot-in in-none none-none TYR APEdihe_nniai APEdist_aaaa P01 Type1 258 - 536 0 None S345N,A370S,Y419W Proto-oncogene tyrosine-protein kinase Src
TYR SRMS SRMS_HUMAN AF-Q9H3Y6-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 222 - 488 0 None None Tyrosine-protein kinase Srms
TYR SRMS SRMS_HUMAN AF-Q9H3Y6-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 222 - 488 0 None None Tyrosine-protein kinase Srms
TYR SYK KSYK_HUMAN 4FL1A 1.79 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa ANP ATPlike 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN AF-P43405-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 362 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN AF-P43405-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 362 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 4XG2A 2.21 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_niiai APEdist_aaaa No_ligand No_ligand 364 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 1XBAA 2.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 4F4PA 2.37 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 0SB Type1 365 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 4DFLA 1.98 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out TYR APEdihe_oiiai APEdist_aaaa 0K0 Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 4DFNA 2.48 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 0K1 Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 4PV0A 2.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa CG4 Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 6HM6A 2.1 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa GDK Type1 364 - 632 0 PTR525 None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 6HM7A 1.64 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_nniai APEdist_aaaa GDH Type1 363 - 633 0 PTR525 None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 3SRVA 1.95 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa S19 Type1 364 - 634 0 PTR525 None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 3SRVB 1.95 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa S19 Type1 364 - 632 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 5LMAA 1.43 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa 6ZG Type1 363 - 632 0 PTR525 None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 5LMBA 1.95 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa 6ZF Type1 364 - 634 0 PTR525 None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 5LMBB 1.95 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_nniai APEdist_aaaa 6ZF Type1 364 - 630 0 PTR525 None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 8X5KA 1.8 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_nnnai APEdist_aaaa 3YT Type1 363 - 632 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 6VOVA 1.95 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_nniai APEdist_aaaa R6D Type1 363 - 629 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 6VOVB 1.95 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa R6D Type1 364 - 633 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 4YJOA 1.6 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 4DF Type1 363 - 632 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 4YJPA 1.83 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa 4DL Type1 364 - 632 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 4YJQA 1.34 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-in TYR APEdihe_iiiai APEdist_aaaa 4DK Type1 364 - 633 0 PTR525,PTR526 None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 4YJRA 1.32 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-in TYR APEdihe_iiiai APEdist_aaaa 4DJ Type1 364 - 633 0 PTR525,PTR526 None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 4YJSA 2.22 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa 4DN Type1 364 - 632 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 4YJTA 1.52 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-in TYR APEdihe_iiiai APEdist_aaaa 4DQ Type1 364 - 633 0 PTR525,PTR526 None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 4YJUA 1.67 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-in TYR APEdihe_iiiai APEdist_aaaa 4DO Type1 364 - 633 0 PTR525,PTR526 None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 4YJVA 1.652 Inactive DFGin‑BLAminus DFGAsp-rot-in in-out in-in TYR APEdihe_iiiai APEdist_aaaa 4DT Type1 364 - 633 0 PTR525,PTR526 None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 8RRQA 1.6 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1H2W Type1 363 - 632 0 PTR525,PTR526 None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 8RRZA 1.75 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_nniai APEdist_aaaa A1H2Y Type1 363 - 633 0 PTR525,PTR526 None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 5TR6A 1.93 Inactive DFGin‑BLAminus DFGAsp-rot-out in-none in-in TYR APEdihe_iiiai APEdist_aaaa 7KG Type1 362 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 5TT7A 1.77 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa 7KF Type1 358 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 4RSSA 1.83 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oooai APEdist_aaaa 4MG Type1 364 - 634 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 4XG3A 2.3 Inactive DFGin‑BLAminus DFGAsp-rot-out in-out in-in TYR APEdihe_iiiai APEdist_aaaa X3G Type1 363 - 634 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 4XG3B 2.3 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_niiai APEdist_aaaa X3G Type1 363 - 633 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 4XG4A 2.3 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_niiai APEdist_aaaa X4G Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 4XG6A 2.4 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_nnnai APEdist_aaaa X6G Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 4XG7A 1.76 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-out TYR APEdihe_oooai APEdist_aaaa X7G Type1 364 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 4XG8A 2.4 Inactive DFGin‑BLAminus DFGAsp-rot-out in-out in-none TYR APEdihe_nnnai APEdist_aaaa X8G Type1 366 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 4XG8C 2.4 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_nnnai APEdist_aaaa X8G Type1 364 - 629 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 4XG9A 2.91 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_nnnai APEdist_aaaa X9G Type1 363 - 632 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 4XG9B 2.91 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_nnnai APEdist_aaaa X9G Type1 363 - 634 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 5GHVA 2.8 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_niiai APEdist_aaaa X5G Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 5GHVB 2.8 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_niiai APEdist_aaaa X5G Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 8XQ0A 1.95 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1LV4 Type1 364 - 634 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 8XQ0B 1.95 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_niiai APEdist_aaaa A1LV4 Type1 364 - 634 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 8XQ0C 1.95 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa A1LV4 Type1 364 - 633 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 8XQ0D 1.95 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_niiai APEdist_aaaa A1LV4 Type1 364 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 8XQ1A 1.5 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_niiai APEdist_aaaa A1LV6 Type1 364 - 634 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 8XQ1B 1.5 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_niiai APEdist_aaaa A1LV6 Type1 364 - 634 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 8XQ2A 1.8 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_nnnai APEdist_aaaa A1LV7 Type1 363 - 634 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 8XQ2B 1.8 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_niiai APEdist_aaaa A1LV7 Type1 364 - 632 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 1XBBA 1.57 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa STI Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 1XBCA 2.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa STU Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 3FQEA 2.5 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_niiai APEdist_aaaa P5C Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 3FQHA 2.26 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 057 Type1 363 - 634 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 3FQHB 2.26 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa 057 Type1 363 - 633 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 3FQSA 2.1 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa 585 Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 4FYNA 2.318 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa 0VE Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 4FYOA 1.4 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_niiai APEdist_aaaa 0VF Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 4FZ6A 1.85 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa 0VG Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 4FZ7A 1.75 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_niiai APEdist_aaaa 0VH Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 4GFGA 2.35 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa 0XF Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 4I0RA 2.1 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa 1B4 Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 4I0SA 1.98 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa 1B5 Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 4I0TA 1.7 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 1B6 Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 4PUZA 2.085 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_niiai APEdist_aaaa CG9 Type1 363 - 633 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 4PUZB 2.085 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_niiai APEdist_aaaa CG9 Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 5T68A 2.93 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa 77V Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 5T68B 2.93 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_niiai APEdist_aaaa 77V Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 5TIUA 1.49 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa 7CU Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 3EMGA 2.6 Inactive DFGin‑BLAminus DFGAsp-rot-out in-out in-none TYR APEdihe_niiai APEdist_aaaa 685 Type1 365 - 631 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 5Y5TA 1.8 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa 8OR Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 5Y5UA 2.14 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 8OU Type1 364 - 634 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 5Y5UB 2.14 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nnnai APEdist_aaaa 8OU Type1 363 - 629 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 8WYWA 1.9 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_nnnai APEdist_aaaa XFB Type1 364 - 633 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 8WYWB 1.9 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_nnnai APEdist_aaaa XFB Type1 365 - 633 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 3VF8A 2.08 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in TYR APEdihe_iiiai APEdist_aaaa 0JE Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 3VF9A 2.3 None DFGin‑BLAminus DFGAsp-rot-in in-none in-in TYR APEdihe_iiiai APEdist_aaaa 477 Type1 364 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 4WNMA 2.5 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 3RT Type1 347 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 5C26A 1.95 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 50H Type1 363 - 635 0 PTR525,PTR526 None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 5C27A 2.15 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa 50J Type1 363 - 635 0 PTR525,PTR526 None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 6SSBA 2.08 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_niiai APEdist_aaaa LUE Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 6ZC0A 1.97 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa QDZ Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 6ZCPA 2.2 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-in TYR APEdihe_iiiai APEdist_aaaa QFK Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 6ZCQA 2.32 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_niiai APEdist_aaaa QFB Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 6ZCRA 1.73 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 5JG Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 6ZCSA 1.47 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_niiai APEdist_aaaa QFE Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 6ZCUA 1.73 None DFGin‑BLAminus DFGAsp-rot-in in-in in-none TYR APEdihe_nniai APEdist_aaaa 5JG Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 6ZCXA 1.66 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_niiai APEdist_aaaa QFQ Type1 363 - 635 0 None None Tyrosine-protein kinase SYK
TYR SYK KSYK_HUMAN 6ZCYA 1.81 Inactive DFGin‑BLAminus DFGAsp-rot-out in-in in-none TYR APEdihe_niiai APEdist_aaaa