PDB: AF-P45985 — STE MP2K4_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P45985-K1A
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K4 MP2K4_HUMAN AF-P45985-K1A P45985 94 375 399.0 No_ligand No_ligand Active DFGin 6.024 13.974 BLAminus -144.38, 178.82 63.15, 66.23 -90.49, 12.46 311.33, 100.8 -64.94, -20.08 na-na na 7.645 Saltbr-na 2.655 HRD-in -77.58, -44.7 69.19, 5.56 na-in-in SNCaii in-in ActLoopNT-in 2.828 ActLoopCT-in nonTYR APEdihe_aaiai APEdist_iiii APE10-dihe-na -76.72, 152.93 APE9-dihe-na 95.32, 163.65 APE8-dihe-in -74.41, 113.18 APE8-rot-na 195.25 APE67-dihe-in -63.87, -25.53 -48.12, -43.55 APE12-dist-in 12.52 APE11-dist-in 10.176 APE10-dist-in 5.251 APE9-dist-in 3.388 None None None AF2 -1.0 1.0 1.0 A 282 282 0 0 0 0 [[102, 367]] 1.0 AF-P45985-K1 STE_MAP2K4_HUMAN STE 4e-86 294.5 4 257 254 246 247 248 250 252 131 148 152 226 228 227 229 289 273 268 267 266 265 264 263 262 179 Dual specificity mitogen-activated protein kinase kinase 4
STE MAP2K4 MP2K4_HUMAN AF-P45985-K3A P45985 94 375 399.0 No_ligand No_ligand Active DFGin 6.014 13.855 BLAminus -145.68, 178.46 65.47, 68.56 -89.98, 4.77 304.41, 100.58 -59.88, -23.06 na-na na 7.914 Saltbr-na 2.738 HRD-in -79.54, -41.27 70.86, 3.15 na-in-in SNCaii in-in ActLoopNT-in 2.824 ActLoopCT-in nonTYR APEdihe_aaiai APEdist_iiii APE10-dihe-na -126.15, 138.91 APE9-dihe-na 114.31, 163.57 APE8-dihe-in -74.18, 105.58 APE8-rot-na 193.37 APE67-dihe-in -50.19, -39.32 -41.21, -47.27 APE12-dist-in 12.139 APE11-dist-in 10.38 APE10-dist-in 5.065 APE9-dist-in 3.571 None None None AF2 -1.0 1.0 1.0 A 282 282 0 0 0 0 [[102, 367]] 1.0 AF-P45985-K3 STE_MAP2K4_HUMAN STE 4e-86 294.5 4 257 254 246 247 248 250 252 131 148 152 226 228 227 229 289 273 268 267 266 265 264 263 262 179 Dual specificity mitogen-activated protein kinase kinase 4

PDB: AF-P45985 — STE MP2K4_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P45985-K1A
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K4 MP2K4_HUMAN AF-P45985-K1A P45985 94 375 399.0 No_ligand No_ligand Active DFGin 6.024 13.974 BLAminus -144.38, 178.82 63.15, 66.23 -90.49, 12.46 311.33, 100.8 -64.94, -20.08 na-na na 7.645 Saltbr-na 2.655 HRD-in -77.58, -44.7 69.19, 5.56 na-in-in SNCaii in-in ActLoopNT-in 2.828 ActLoopCT-in nonTYR APEdihe_aaiai APEdist_iiii APE10-dihe-na -76.72, 152.93 APE9-dihe-na 95.32, 163.65 APE8-dihe-in -74.41, 113.18 APE8-rot-na 195.25 APE67-dihe-in -63.87, -25.53 -48.12, -43.55 APE12-dist-in 12.52 APE11-dist-in 10.176 APE10-dist-in 5.251 APE9-dist-in 3.388 None None None AF2 -1.0 1.0 1.0 A 282 282 0 0 0 0 [[102, 367]] 1.0 AF-P45985-K1 Homo sapiens STE_MAP2K4_HUMAN STE 4e-86 294.5 4 257 254 246 247 248 250 252 131 148 152 226 228 227 229 289 273 268 267 266 265 264 263 262 179 Dual specificity mitogen-activated protein kinase kinase 4
STE MAP2K4 MP2K4_HUMAN AF-P45985-K3A P45985 94 375 399.0 No_ligand No_ligand Active DFGin 6.014 13.855 BLAminus -145.68, 178.46 65.47, 68.56 -89.98, 4.77 304.41, 100.58 -59.88, -23.06 na-na na 7.914 Saltbr-na 2.738 HRD-in -79.54, -41.27 70.86, 3.15 na-in-in SNCaii in-in ActLoopNT-in 2.824 ActLoopCT-in nonTYR APEdihe_aaiai APEdist_iiii APE10-dihe-na -126.15, 138.91 APE9-dihe-na 114.31, 163.57 APE8-dihe-in -74.18, 105.58 APE8-rot-na 193.37 APE67-dihe-in -50.19, -39.32 -41.21, -47.27 APE12-dist-in 12.139 APE11-dist-in 10.38 APE10-dist-in 5.065 APE9-dist-in 3.571 None None None AF2 -1.0 1.0 1.0 A 282 282 0 0 0 0 [[102, 367]] 1.0 AF-P45985-K3 Homo sapiens STE_MAP2K4_HUMAN STE 4e-86 294.5 4 257 254 246 247 248 250 252 131 148 152 226 228 227 229 289 273 268 267 266 265 264 263 262 179 Dual specificity mitogen-activated protein kinase kinase 4

PDB: AF-P45985 — STE MP2K4_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name