PDB: AF-P41279 — STE M3K8_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P41279-K1A
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP3K8 M3K8_HUMAN AF-P41279-K1A P41279 119 396 467.0 No_ligand No_ligand Active DFGin 6.294 13.982 BLAminus -129.98, 170.56 63.15, 76.35 -89.44, 13.76 292.02, 84.03 -62.49, -20.45 na-na na 8.348 Saltbr-na 4.854 HRD-in -76.0, -40.02 66.91, -3.01 na-in-in SNCaii in-in ActLoopNT-in 2.894 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -130.22, 142.15 APE9-dihe-na 109.14, -178.88 APE8-dihe-in -88.67, 116.19 APE8-rot-in 300.57 APE67-dihe-in -71.19, -17.01 -38.1, -48.69 APE12-dist-in 10.042 APE11-dist-in 11.282 APE10-dist-in 5.803 APE9-dist-in 3.073 None None None AF2 -1.0 1.0 1.0 A 278 278 0 0 0 0 [[136, 388]] 1.0 AF-P41279-K1 STE_MAP3K8_HUMAN STE 5.3e-75 258.0 7 256 250 269 270 271 273 275 167 178 182 250 252 251 253 309 297 292 291 290 289 288 287 286 208 Mitogen-activated protein kinase kinase kinase 8
STE MAP3K8 M3K8_HUMAN AF-P41279-K3A P41279 119 396 467.0 No_ligand No_ligand Active DFGin 5.942 13.983 BLAminus -131.03, 168.69 61.73, 83.17 -92.92, 11.71 290.77, 81.48 -62.9, -19.69 na-na na 8.302 Saltbr-na 5.038 HRD-in -78.24, -37.73 70.07, -5.97 na-in-in SNCaii in-in ActLoopNT-in 2.917 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -130.03, 134.67 APE9-dihe-na 113.33, -170.09 APE8-dihe-in -99.29, 119.72 APE8-rot-in 301.36 APE67-dihe-in -72.35, 0.42 -41.59, -48.77 APE12-dist-in 10.179 APE11-dist-in 10.909 APE10-dist-in 5.58 APE9-dist-in 3.061 None None None AF2 -1.0 1.0 1.0 A 278 278 0 0 0 0 [[136, 388]] 1.0 AF-P41279-K3 STE_MAP3K8_HUMAN STE 5.3e-75 258.0 7 256 250 269 270 271 273 275 167 178 182 250 252 251 253 309 297 292 291 290 289 288 287 286 208 Mitogen-activated protein kinase kinase kinase 8

PDB: AF-P41279 — STE M3K8_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P41279-K1A
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP3K8 M3K8_HUMAN AF-P41279-K1A P41279 119 396 467.0 No_ligand No_ligand Active DFGin 6.294 13.982 BLAminus -129.98, 170.56 63.15, 76.35 -89.44, 13.76 292.02, 84.03 -62.49, -20.45 na-na na 8.348 Saltbr-na 4.854 HRD-in -76.0, -40.02 66.91, -3.01 na-in-in SNCaii in-in ActLoopNT-in 2.894 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -130.22, 142.15 APE9-dihe-na 109.14, -178.88 APE8-dihe-in -88.67, 116.19 APE8-rot-in 300.57 APE67-dihe-in -71.19, -17.01 -38.1, -48.69 APE12-dist-in 10.042 APE11-dist-in 11.282 APE10-dist-in 5.803 APE9-dist-in 3.073 None None None AF2 -1.0 1.0 1.0 A 278 278 0 0 0 0 [[136, 388]] 1.0 AF-P41279-K1 Homo sapiens STE_MAP3K8_HUMAN STE 5.3e-75 258.0 7 256 250 269 270 271 273 275 167 178 182 250 252 251 253 309 297 292 291 290 289 288 287 286 208 Mitogen-activated protein kinase kinase kinase 8
STE MAP3K8 M3K8_HUMAN AF-P41279-K3A P41279 119 396 467.0 No_ligand No_ligand Active DFGin 5.942 13.983 BLAminus -131.03, 168.69 61.73, 83.17 -92.92, 11.71 290.77, 81.48 -62.9, -19.69 na-na na 8.302 Saltbr-na 5.038 HRD-in -78.24, -37.73 70.07, -5.97 na-in-in SNCaii in-in ActLoopNT-in 2.917 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -130.03, 134.67 APE9-dihe-na 113.33, -170.09 APE8-dihe-in -99.29, 119.72 APE8-rot-in 301.36 APE67-dihe-in -72.35, 0.42 -41.59, -48.77 APE12-dist-in 10.179 APE11-dist-in 10.909 APE10-dist-in 5.58 APE9-dist-in 3.061 None None None AF2 -1.0 1.0 1.0 A 278 278 0 0 0 0 [[136, 388]] 1.0 AF-P41279-K3 Homo sapiens STE_MAP3K8_HUMAN STE 5.3e-75 258.0 7 256 250 269 270 271 273 275 167 178 182 250 252 251 253 309 297 292 291 290 289 288 287 286 208 Mitogen-activated protein kinase kinase kinase 8

PDB: AF-P41279 — STE M3K8_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name