MAP3K8 (Mitogen-activated protein kinase kinase kinase 8)

Group: STE

Uniprot: M3K8_HUMAN

Domain boundary: 127 - 388

Total number of chains: 9

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	9	AF-P41279-K1A

Database table as tsv

PDB	Resolution	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Mutation	Phosphorylation	Unresolved residues in A-loop
AF-P41279-K1A	-1.0	Active	DFGin	BLAminus	in-in	in-in	No_ligand	No_ligand	119 - 396	None	None	0
4Y83A	2.89	Active	DFGin	BLAminus	in-in	in-in	49B	Type1	73 - 389	None	None	0
4Y83B	2.89	Active	DFGin	BLAminus	in-in	in-in	49B	Type1	73 - 390	None	None	0
4Y83C	2.89	None	DFGin	BLAminus	in-none	in-in	49B	Type1	74 - 389	None	None	1
4Y85A	2.33	Active	DFGin	BLAminus	in-in	in-in	499	Type1	73 - 390	None	None	0
4Y85B	2.33	Active	DFGin	BLAminus	in-in	in-in	499	Type1	73 - 390	None	None	0
4Y85C	2.33	Active	DFGin	BLAminus	in-in	in-in	499	Type1	73 - 390	None	None	0
5IU2A	2.7	Inactive	DFGin	BLAminus	in-out	in-in	6DA	Type1	73 - 389	None	None	0
5IU2B	2.7	Inactive	DFGin	BLAminus	in-out	in-in	6DA	Type1	73 - 389	None	None	0

MAP3K8 (Mitogen-activated protein kinase kinase kinase 8)

Group: STE

Total number of chains: 9

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	9	AF-P41279-K1A

Database table as tsv

Organism	UniprotID	PDB	Resolution	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Mutation	Phosphorylation	Unresolved residues in A-loop
Homo sapiens	M3K8_HUMAN	AF-P41279-K1A	-1.0	Active	DFGin	BLAminus	in-in	in-in	No_ligand	No_ligand	119 - 396	None	None	0
Homo sapiens	M3K8_HUMAN	4Y83A	2.89	Active	DFGin	BLAminus	in-in	in-in	49B	Type1	73 - 389	None	None	0
Homo sapiens	M3K8_HUMAN	4Y83B	2.89	Active	DFGin	BLAminus	in-in	in-in	49B	Type1	73 - 390	None	None	0
Homo sapiens	M3K8_HUMAN	4Y83C	2.89	None	DFGin	BLAminus	in-none	in-in	49B	Type1	74 - 389	None	None	1
Homo sapiens	M3K8_HUMAN	4Y85A	2.33	Active	DFGin	BLAminus	in-in	in-in	499	Type1	73 - 390	None	None	0
Homo sapiens	M3K8_HUMAN	4Y85B	2.33	Active	DFGin	BLAminus	in-in	in-in	499	Type1	73 - 390	None	None	0
Homo sapiens	M3K8_HUMAN	4Y85C	2.33	Active	DFGin	BLAminus	in-in	in-in	499	Type1	73 - 390	None	None	0
Homo sapiens	M3K8_HUMAN	5IU2A	2.7	Inactive	DFGin	BLAminus	in-out	in-in	6DA	Type1	73 - 389	None	None	0
Homo sapiens	M3K8_HUMAN	5IU2B	2.7	Inactive	DFGin	BLAminus	in-out	in-in	6DA	Type1	73 - 389	None	None	0

MAP3K8 (Mitogen-activated protein kinase kinase kinase 8)

No non-human structures known.