PDB: AF-P27037 — TKL AVR2A_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P27037-K1A

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR2A AVR2A_HUMAN AF-P27037-K1A P27037 184 489 513.0 No_ligand No_ligand Active DFGin 7.269 13.7003 BLAminus -137.45, 169.69 67.25, 68.52 -84.71, 16.97 304.39, 108.34 -63.28, -19.76 in-in in 7.8867 Saltbr-in 2.6721 HRD-in -85.43, -41.28 66.31, 6.96 in-in-in SNCiii in-in ActLoopNT-in 2.8788 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -99.89, 156.32 APE9-dihe-na 105.55, -169.46 APE8-dihe-in -93.07, 118.12 APE8-rot-in 303.12 APE67-dihe-in -59.36, -25.82 -49.75, -42.86 APE12-dist-in 10.7018 APE11-dist-in 12.4807 APE10-dist-in 6.3872 APE9-dist-in 3.4511 None None None AF2 -1.0 1.0 1.0 A 306.0 306.0 0 30 30 0 [[192, 481]] 1.0 AF-P27037-K1 TKL_ACVR2A_HUMAN TKL 2.9e-83 285.4 2.0 266.0 265.0 339 340 341 343 345 219 232 236 319 321 320 322.0 386 369 364 363 362 361 360 359 358 268 Activin receptor type-2A
TKL ACVR2A AVR2A_HUMAN AF-P27037-K3A P27037 184 489 513.0 No_ligand No_ligand Active DFGin 6.7063 13.9826 BLAminus -138.42, 173.36 68.77, 61.7 -77.85, 18.77 302.81, 110.47 -60.19, -21.37 in-in in 7.8878 Saltbr-in 2.7307 HRD-in -81.7, -38.65 63.48, 6.34 in-in-in SNCiii in-in ActLoopNT-in 2.8396 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -127.93, 163.23 APE9-dihe-na 97.04, -163.98 APE8-dihe-in -90.36, 115.81 APE8-rot-in 304.87 APE67-dihe-in -57.74, -26.76 -42.5, -46.12 APE12-dist-in 10.3774 APE11-dist-in 12.1036 APE10-dist-in 6.1819 APE9-dist-in 3.6194 None None None AF2 -1.0 1.0 1.0 A 306.0 306.0 0 30 30 0 [[192, 481]] 1.0 AF-P27037-K3 TKL_ACVR2A_HUMAN TKL 2.9e-83 285.4 2.0 266.0 265.0 339 340 341 343 345 219 232 236 319 321 320 322.0 386 369 364 363 362 361 360 359 358 268 Activin receptor type-2A

PDB: AF-P27037 — TKL AVR2A_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P27037-K1A

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR2A AVR2A_HUMAN AF-P27037-K1A P27037 184 489 513.0 No_ligand No_ligand Active DFGin 7.269 13.7003 BLAminus -137.45, 169.69 67.25, 68.52 -84.71, 16.97 304.39, 108.34 -63.28, -19.76 in-in in 7.8867 Saltbr-in 2.6721 HRD-in -85.43, -41.28 66.31, 6.96 in-in-in SNCiii in-in ActLoopNT-in 2.8788 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -99.89, 156.32 APE9-dihe-na 105.55, -169.46 APE8-dihe-in -93.07, 118.12 APE8-rot-in 303.12 APE67-dihe-in -59.36, -25.82 -49.75, -42.86 APE12-dist-in 10.7018 APE11-dist-in 12.4807 APE10-dist-in 6.3872 APE9-dist-in 3.4511 None None None AF2 -1.0 1.0 1.0 A 306.0 306.0 0 30 30 0 [[192, 481]] 1.0 AF-P27037-K1 Homo sapiens TKL_ACVR2A_HUMAN TKL 2.9e-83 285.4 2.0 266.0 265.0 339 340 341 343 345 219 232 236 319 321 320 322.0 386 369 364 363 362 361 360 359 358 268 Activin receptor type-2A
TKL ACVR2A AVR2A_HUMAN AF-P27037-K3A P27037 184 489 513.0 No_ligand No_ligand Active DFGin 6.7063 13.9826 BLAminus -138.42, 173.36 68.77, 61.7 -77.85, 18.77 302.81, 110.47 -60.19, -21.37 in-in in 7.8878 Saltbr-in 2.7307 HRD-in -81.7, -38.65 63.48, 6.34 in-in-in SNCiii in-in ActLoopNT-in 2.8396 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -127.93, 163.23 APE9-dihe-na 97.04, -163.98 APE8-dihe-in -90.36, 115.81 APE8-rot-in 304.87 APE67-dihe-in -57.74, -26.76 -42.5, -46.12 APE12-dist-in 10.3774 APE11-dist-in 12.1036 APE10-dist-in 6.1819 APE9-dist-in 3.6194 None None None AF2 -1.0 1.0 1.0 A 306.0 306.0 0 30 30 0 [[192, 481]] 1.0 AF-P27037-K3 Homo sapiens TKL_ACVR2A_HUMAN TKL 2.9e-83 285.4 2.0 266.0 265.0 339 340 341 343 345 219 232 236 319 321 320 322.0 386 369 364 363 362 361 360 359 358 268 Activin receptor type-2A

PDB: AF-P27037 — TKL AVR2A_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name