PDB: AF-O43318 — TKL M3K7_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-O43318-K1A
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL MAP3K7 M3K7_HUMAN AF-O43318-K1A O43318 28 294 606.0 No_ligand No_ligand Active DFGin 6.437 14.258 BLAminus -135.91, -178.44 63.71, 68.23 -88.2, 14.53 289.23, 76.3 -60.56, -24.27 in-in in 7.844 Saltbr-in 2.672 HRD-in -75.91, -47.08 68.67, 3.27 in-in-in SNCiii in-in ActLoopNT-in 2.87 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -130.71, 151.71 APE9-dihe-na 102.26, -179.87 APE8-dihe-in -97.74, 129.86 APE8-rot-in 305.09 APE67-dihe-in -73.84, -18.7 -49.97, -40.78 APE12-dist-in 9.189 APE11-dist-in 11.449 APE10-dist-in 5.51 APE9-dist-in 3.423 None None None AF2 -1.0 1.0 1.0 A 267 267 0 0 0 0 [[36, 286]] 1.0 AF-O43318-K1 TKL_MAP3K7_HUMAN TKL 2.2e-74 256.2 2 266 265 174 175 176 178 180 63 77 81 153 155 154 156 211 199 194 193 192 191 190 189 188 105 Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K7 M3K7_HUMAN AF-O43318-K3A O43318 28 294 606.0 No_ligand No_ligand Active DFGin 6.163 14.349 BLAminus -135.99, -175.25 61.0, 63.16 -80.15, 10.99 286.81, 77.67 -61.53, -24.03 in-in in 7.663 Saltbr-in 2.663 HRD-in -76.91, -44.69 67.08, -10.08 in-in-in SNCiii in-in ActLoopNT-in 2.887 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.75, 152.82 APE9-dihe-na 113.89, 175.31 APE8-dihe-in -97.7, 130.55 APE8-rot-in 301.49 APE67-dihe-in -73.62, -12.95 -49.26, -40.76 APE12-dist-in 9.244 APE11-dist-in 11.291 APE10-dist-in 5.341 APE9-dist-in 3.204 None None None AF2 -1.0 1.0 1.0 A 267 267 0 0 0 0 [[36, 286]] 1.0 AF-O43318-K3 TKL_MAP3K7_HUMAN TKL 2.2e-74 256.2 2 266 265 174 175 176 178 180 63 77 81 153 155 154 156 211 199 194 193 192 191 190 189 188 105 Mitogen-activated protein kinase kinase kinase 7

PDB: AF-O43318 — TKL M3K7_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-O43318-K1A
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL MAP3K7 M3K7_HUMAN AF-O43318-K1A O43318 28 294 606.0 No_ligand No_ligand Active DFGin 6.437 14.258 BLAminus -135.91, -178.44 63.71, 68.23 -88.2, 14.53 289.23, 76.3 -60.56, -24.27 in-in in 7.844 Saltbr-in 2.672 HRD-in -75.91, -47.08 68.67, 3.27 in-in-in SNCiii in-in ActLoopNT-in 2.87 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -130.71, 151.71 APE9-dihe-na 102.26, -179.87 APE8-dihe-in -97.74, 129.86 APE8-rot-in 305.09 APE67-dihe-in -73.84, -18.7 -49.97, -40.78 APE12-dist-in 9.189 APE11-dist-in 11.449 APE10-dist-in 5.51 APE9-dist-in 3.423 None None None AF2 -1.0 1.0 1.0 A 267 267 0 0 0 0 [[36, 286]] 1.0 AF-O43318-K1 Homo sapiens TKL_MAP3K7_HUMAN TKL 2.2e-74 256.2 2 266 265 174 175 176 178 180 63 77 81 153 155 154 156 211 199 194 193 192 191 190 189 188 105 Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K7 M3K7_HUMAN AF-O43318-K3A O43318 28 294 606.0 No_ligand No_ligand Active DFGin 6.163 14.349 BLAminus -135.99, -175.25 61.0, 63.16 -80.15, 10.99 286.81, 77.67 -61.53, -24.03 in-in in 7.663 Saltbr-in 2.663 HRD-in -76.91, -44.69 67.08, -10.08 in-in-in SNCiii in-in ActLoopNT-in 2.887 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.75, 152.82 APE9-dihe-na 113.89, 175.31 APE8-dihe-in -97.7, 130.55 APE8-rot-in 301.49 APE67-dihe-in -73.62, -12.95 -49.26, -40.76 APE12-dist-in 9.244 APE11-dist-in 11.291 APE10-dist-in 5.341 APE9-dist-in 3.204 None None None AF2 -1.0 1.0 1.0 A 267 267 0 0 0 0 [[36, 286]] 1.0 AF-O43318-K3 Homo sapiens TKL_MAP3K7_HUMAN TKL 2.2e-74 256.2 2 266 265 174 175 176 178 180 63 77 81 153 155 154 156 211 199 194 193 192 191 190 189 188 105 Mitogen-activated protein kinase kinase kinase 7

PDB: AF-O43318 — TKL M3K7_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name