PDB: 9UW4 — 2 kinases

Total number of chains: 2
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 9UW4B
All chains
Pymol session (all) Pymol script (all)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label DFG-Asp_rot_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Asp
χ1,χ2		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK3 MK03_HUMAN 9UW4B P27361 29 374 379.0 ANP:402 ATPlike Inactive DFGin 6.904 15.983 BLAminus DFGAsp-rot-in -137.547, -167.3693 59.7522, 64.3544 201.1871, -43.5971 -88.5285, 51.6599 292.6306, 79.5591 -72.0921, -64.5527 in-out in 9.85 Saltbr-out 4.731 HRD-in -63.7037, -42.698 63.7695, 2.2218 out-in-out SNCoio in-out ActLoopNT-in 3.119 ActLoopCT-out nonTYR APEdihe_aaioo APEdist_oooo APE10-dihe-na -71.7213, 146.7494 APE9-dihe-na -156.6838, 164.4469 APE8-dihe-in -95.2675, 129.2723 APE8-rot-out 86.0069 APE67-dihe-out -93.875, -29.8394 -129.7461, 119.2822 APE12-dist-out 16.501 APE11-dist-out 16.066 APE10-dist-out 18.486 APE9-dist-out 13.259 None None None EM 3.2 999.0 999.0 B 388 346 0 0 0 0 [[42, 330]] 1.0 9uw4 CMGC_MAPK3_HUMAN CMGC 3.5e-87 298.4 1 301 301 183 184 185 187 189 71 88 92 163 165 164 166 227 214 209 208 207 206 205 204 203 123 Mitogen-activated protein kinase 3
STE MAP2K1 MP2K1_HUMAN 9UW4A Q02750 2 375 393.0 ANP:501 ATPlike Active DFGin 6.485 14.599 BLAminus DFGAsp-rot-in -136.4356, -166.9181 62.7805, 63.0181 190.2689, 2.7254 -89.0731, 54.8846 301.129, 106.902 -87.1074, -57.2446 in-in in 9.002 Saltbr-in 2.853 HRD-in -62.1932, -43.6112 67.571, -2.9137 in-in-in SNCiii in-in ActLoopNT-in 3.164 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.5088, 158.6976 APE9-dihe-na 119.6095, 172.9557 APE8-dihe-in -67.7643, 140.1554 APE8-rot-in 312.1459 APE67-dihe-in -66.6241, -41.137 -75.294, -36.0582 APE12-dist-in 9.165 APE11-dist-in 11.215 APE10-dist-in 5.441 APE9-dist-in 4.321 None SEP218,SEP222 SEP218,SEP222 EM 3.2 999.0 999.0 A 403 306 30 0 0 0 [[68, 361]] 1.0 9uw4 STE_MAP2K1_HUMAN STE 2.7e-97 331.3 1 257 257 207 208 209 211 213 97 114 118 187 189 188 190 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1

PDB: 9UW4 — 2 kinases

Total number of chains: 2
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 9UW4B
All chains
Pymol session (all) Pymol script (all)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label DFG-Asp_rot_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Asp
χ1,χ2		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK3 MK03_HUMAN 9UW4B P27361 29 374 379.0 ANP:402 ATPlike Inactive DFGin 6.904 15.983 BLAminus DFGAsp-rot-in -137.547, -167.3693 59.7522, 64.3544 201.1871, -43.5971 -88.5285, 51.6599 292.6306, 79.5591 -72.0921, -64.5527 in-out in 9.85 Saltbr-out 4.731 HRD-in -63.7037, -42.698 63.7695, 2.2218 out-in-out SNCoio in-out ActLoopNT-in 3.119 ActLoopCT-out nonTYR APEdihe_aaioo APEdist_oooo APE10-dihe-na -71.7213, 146.7494 APE9-dihe-na -156.6838, 164.4469 APE8-dihe-in -95.2675, 129.2723 APE8-rot-out 86.0069 APE67-dihe-out -93.875, -29.8394 -129.7461, 119.2822 APE12-dist-out 16.501 APE11-dist-out 16.066 APE10-dist-out 18.486 APE9-dist-out 13.259 None None None EM 3.2 999.0 999.0 B 388 346 0 0 0 0 [[42, 330]] 1.0 9uw4 Homo sapiens CMGC_MAPK3_HUMAN CMGC 3.5e-87 298.4 1 301 301 183 184 185 187 189 71 88 92 163 165 164 166 227 214 209 208 207 206 205 204 203 123 Mitogen-activated protein kinase 3
STE MAP2K1 MP2K1_HUMAN 9UW4A Q02750 2 375 393.0 ANP:501 ATPlike Active DFGin 6.485 14.599 BLAminus DFGAsp-rot-in -136.4356, -166.9181 62.7805, 63.0181 190.2689, 2.7254 -89.0731, 54.8846 301.129, 106.902 -87.1074, -57.2446 in-in in 9.002 Saltbr-in 2.853 HRD-in -62.1932, -43.6112 67.571, -2.9137 in-in-in SNCiii in-in ActLoopNT-in 3.164 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.5088, 158.6976 APE9-dihe-na 119.6095, 172.9557 APE8-dihe-in -67.7643, 140.1554 APE8-rot-in 312.1459 APE67-dihe-in -66.6241, -41.137 -75.294, -36.0582 APE12-dist-in 9.165 APE11-dist-in 11.215 APE10-dist-in 5.441 APE9-dist-in 4.321 None SEP218,SEP222 SEP218,SEP222 EM 3.2 999.0 999.0 A 403 306 30 0 0 0 [[68, 361]] 1.0 9uw4 Homo sapiens STE_MAP2K1_HUMAN STE 2.7e-97 331.3 1 257 257 207 208 209 211 213 97 114 118 187 189 188 190 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1

PDB: 9UW4 — 2 kinases

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label DFG-Asp_rot_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Asp
χ1,χ2		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name