PDB: 9UW3 — 2 kinases

Total number of chains: 2
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 9UW3B
All chains
Pymol session (all) Pymol script (all)
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label DFG-Asp_rot_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Asp
χ1,χ2		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK3 MK03_HUMAN 9UW3B P27361 27 374 379.0 ANP:402 ATPlike Inactive DFGin 6.911 16.194 BLAminus DFGAsp-rot-in -125.6031, -169.6008 62.0638, 57.1616 204.8277, -13.4842 -79.084, 77.2875 280.4089, 80.549 -98.4869, -96.1009 in-in in 9.776 Saltbr-in 3.564 HRD-in -65.0056, -43.9908 63.361, 3.8208 in-in-out SNCiio in-out ActLoopNT-in 3.482 ActLoopCT-out nonTYR APEdihe_aaioo APEdist_oooo APE10-dihe-na -112.9812, 147.8659 APE9-dihe-na -157.6409, 163.2759 APE8-dihe-in -92.3175, 124.3346 APE8-rot-out 75.5113 APE67-dihe-out -87.7767, -4.4272 -128.9449, 106.9042 APE12-dist-out 16.25 APE11-dist-out 15.863 APE10-dist-out 17.941 APE9-dist-out 13.309 None PTR204 PTR204 EM 3.36 999.0 999.0 B 388 348 0 0 0 0 [[42, 330]] 1.0 9uw3 CMGC_MAPK3_HUMAN CMGC 3.5e-87 298.4 1 301 301 183 184 185 187 189 71 88 92 163 165 164 166 227 214 209 208 207 206 205 204 203 123 Mitogen-activated protein kinase 3
STE MAP2K1 MP2K1_HUMAN 9UW3A Q02750 2 366 393.0 ANP:501 ATPlike Active DFGin 6.548 14.061 BLAminus DFGAsp-rot-in -133.3184, -172.9159 59.8152, 67.0898 182.9892, 24.0338 -88.9844, 26.6871 301.9424, 165.2797 -66.6644, -44.8111 in-in in 9.299 Saltbr-in 3.43 HRD-in -62.9178, -44.2039 66.7179, -1.1147 in-in-in SNCiii in-in ActLoopNT-in 3.082 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.572, -2.0315 APE9-dihe-na -74.5847, 173.279 APE8-dihe-in -82.11, 128.8988 APE8-rot-in 293.8018 APE67-dihe-in -77.2196, -20.8954 -65.0972, -24.0804 APE12-dist-in 9.283 APE11-dist-in 10.784 APE10-dist-in 5.078 APE9-dist-in 4.163 None SEP218,SEP222 SEP218,SEP222 EM 3.36 999.0 999.0 A 403 295 30 0 0 0 [[68, 361]] 1.0 9uw3 STE_MAP2K1_HUMAN STE 2.7e-97 331.3 1 257 257 207 208 209 211 213 97 114 118 187 189 188 190 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1

PDB: 9UW3 — 2 kinases

Total number of chains: 2
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 9UW3B
All chains
Pymol session (all) Pymol script (all)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label DFG-Asp_rot_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Asp
χ1,χ2		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK3 MK03_HUMAN 9UW3B P27361 27 374 379.0 ANP:402 ATPlike Inactive DFGin 6.911 16.194 BLAminus DFGAsp-rot-in -125.6031, -169.6008 62.0638, 57.1616 204.8277, -13.4842 -79.084, 77.2875 280.4089, 80.549 -98.4869, -96.1009 in-in in 9.776 Saltbr-in 3.564 HRD-in -65.0056, -43.9908 63.361, 3.8208 in-in-out SNCiio in-out ActLoopNT-in 3.482 ActLoopCT-out nonTYR APEdihe_aaioo APEdist_oooo APE10-dihe-na -112.9812, 147.8659 APE9-dihe-na -157.6409, 163.2759 APE8-dihe-in -92.3175, 124.3346 APE8-rot-out 75.5113 APE67-dihe-out -87.7767, -4.4272 -128.9449, 106.9042 APE12-dist-out 16.25 APE11-dist-out 15.863 APE10-dist-out 17.941 APE9-dist-out 13.309 None PTR204 PTR204 EM 3.36 999.0 999.0 B 388 348 0 0 0 0 [[42, 330]] 1.0 9uw3 Homo sapiens CMGC_MAPK3_HUMAN CMGC 3.5e-87 298.4 1 301 301 183 184 185 187 189 71 88 92 163 165 164 166 227 214 209 208 207 206 205 204 203 123 Mitogen-activated protein kinase 3
STE MAP2K1 MP2K1_HUMAN 9UW3A Q02750 2 366 393.0 ANP:501 ATPlike Active DFGin 6.548 14.061 BLAminus DFGAsp-rot-in -133.3184, -172.9159 59.8152, 67.0898 182.9892, 24.0338 -88.9844, 26.6871 301.9424, 165.2797 -66.6644, -44.8111 in-in in 9.299 Saltbr-in 3.43 HRD-in -62.9178, -44.2039 66.7179, -1.1147 in-in-in SNCiii in-in ActLoopNT-in 3.082 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.572, -2.0315 APE9-dihe-na -74.5847, 173.279 APE8-dihe-in -82.11, 128.8988 APE8-rot-in 293.8018 APE67-dihe-in -77.2196, -20.8954 -65.0972, -24.0804 APE12-dist-in 9.283 APE11-dist-in 10.784 APE10-dist-in 5.078 APE9-dist-in 4.163 None SEP218,SEP222 SEP218,SEP222 EM 3.36 999.0 999.0 A 403 295 30 0 0 0 [[68, 361]] 1.0 9uw3 Homo sapiens STE_MAP2K1_HUMAN STE 2.7e-97 331.3 1 257 257 207 208 209 211 213 97 114 118 187 189 188 190 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1

PDB: 9UW3 — 2 kinases

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label DFG-Asp_rot_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Asp
χ1,χ2		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name