PDB: 9UUX — 2 kinases

Total number of chains: 2
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 9UUXB
All chains
Pymol session (all) Pymol script (all)
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label DFG-Asp_rot_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Asp
χ1,χ2		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK3 MK03_HUMAN 9UUXB P27361 27 375 379.0 ANP:402 ATPlike Inactive DFGin 6.891 16.04 BLAminus DFGAsp-rot-in -128.6144, -170.7726 60.7427, 64.232 216.4748, -27.5773 -88.6666, 67.791 282.4698, 94.6501 -92.1054, -102.8214 in-out in 9.911 Saltbr-out 3.817 HRD-in -62.507, -44.9226 64.1255, 0.0529 out-in-out SNCoio in-out ActLoopNT-in 3.101 ActLoopCT-out nonTYR APEdihe_aaioo APEdist_oooo APE10-dihe-na -76.5628, 148.2674 APE9-dihe-na -156.7962, 164.5301 APE8-dihe-in -92.5475, 120.8909 APE8-rot-out 64.3077 APE67-dihe-out -82.9887, -10.3381 -122.7899, 105.1205 APE12-dist-out 15.979 APE11-dist-out 15.42 APE10-dist-out 18.001 APE9-dist-out 13.025 None TPO202 TPO202 EM 3.12 999.0 999.0 B 388 349 0 0 0 0 [[42, 330]] 1.0 9uux CMGC_MAPK3_HUMAN CMGC 3.5e-87 298.4 1 301 301 183 184 185 187 189 71 88 92 163 165 164 166 227 214 209 208 207 206 205 204 203 123 Mitogen-activated protein kinase 3
STE MAP2K1 MP2K1_HUMAN 9UUXA Q02750 3 378 393.0 ANP:501 ATPlike Active DFGin 6.218 13.704 BLAminus DFGAsp-rot-in -129.1965, -169.4322 61.1831, 68.3217 183.4366, 19.2396 -89.5904, 27.9924 313.9817, 102.4072 -65.5985, -46.5501 in-in in 9.753 Saltbr-in 3.044 HRD-in -62.4059, -43.5931 65.6968, 2.9587 in-in-in SNCiii in-in ActLoopNT-in 2.996 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.491, 6.8198 APE9-dihe-na -80.5275, -173.3898 APE8-dihe-in -98.8148, 120.2218 APE8-rot-in 294.645 APE67-dihe-in -69.9241, -30.2988 -60.7638, -32.0389 APE12-dist-in 9.176 APE11-dist-in 10.993 APE10-dist-in 5.233 APE9-dist-in 4.088 None SEP218,SEP222 SEP218,SEP222 EM 3.12 999.0 999.0 A 403 308 30 0 0 0 [[68, 361]] 1.0 9uux STE_MAP2K1_HUMAN STE 2.7e-97 331.3 1 257 257 207 208 209 211 213 97 114 118 187 189 188 190 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1

PDB: 9UUX — 2 kinases

Total number of chains: 2
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 9UUXB
All chains
Pymol session (all) Pymol script (all)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label DFG-Asp_rot_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Asp
χ1,χ2		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK3 MK03_HUMAN 9UUXB P27361 27 375 379.0 ANP:402 ATPlike Inactive DFGin 6.891 16.04 BLAminus DFGAsp-rot-in -128.6144, -170.7726 60.7427, 64.232 216.4748, -27.5773 -88.6666, 67.791 282.4698, 94.6501 -92.1054, -102.8214 in-out in 9.911 Saltbr-out 3.817 HRD-in -62.507, -44.9226 64.1255, 0.0529 out-in-out SNCoio in-out ActLoopNT-in 3.101 ActLoopCT-out nonTYR APEdihe_aaioo APEdist_oooo APE10-dihe-na -76.5628, 148.2674 APE9-dihe-na -156.7962, 164.5301 APE8-dihe-in -92.5475, 120.8909 APE8-rot-out 64.3077 APE67-dihe-out -82.9887, -10.3381 -122.7899, 105.1205 APE12-dist-out 15.979 APE11-dist-out 15.42 APE10-dist-out 18.001 APE9-dist-out 13.025 None TPO202 TPO202 EM 3.12 999.0 999.0 B 388 349 0 0 0 0 [[42, 330]] 1.0 9uux Homo sapiens CMGC_MAPK3_HUMAN CMGC 3.5e-87 298.4 1 301 301 183 184 185 187 189 71 88 92 163 165 164 166 227 214 209 208 207 206 205 204 203 123 Mitogen-activated protein kinase 3
STE MAP2K1 MP2K1_HUMAN 9UUXA Q02750 3 378 393.0 ANP:501 ATPlike Active DFGin 6.218 13.704 BLAminus DFGAsp-rot-in -129.1965, -169.4322 61.1831, 68.3217 183.4366, 19.2396 -89.5904, 27.9924 313.9817, 102.4072 -65.5985, -46.5501 in-in in 9.753 Saltbr-in 3.044 HRD-in -62.4059, -43.5931 65.6968, 2.9587 in-in-in SNCiii in-in ActLoopNT-in 2.996 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.491, 6.8198 APE9-dihe-na -80.5275, -173.3898 APE8-dihe-in -98.8148, 120.2218 APE8-rot-in 294.645 APE67-dihe-in -69.9241, -30.2988 -60.7638, -32.0389 APE12-dist-in 9.176 APE11-dist-in 10.993 APE10-dist-in 5.233 APE9-dist-in 4.088 None SEP218,SEP222 SEP218,SEP222 EM 3.12 999.0 999.0 A 403 308 30 0 0 0 [[68, 361]] 1.0 9uux Homo sapiens STE_MAP2K1_HUMAN STE 2.7e-97 331.3 1 257 257 207 208 209 211 213 97 114 118 187 189 188 190 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1

PDB: 9UUX — 2 kinases

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label DFG-Asp_rot_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Asp
χ1,χ2		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name