PDB: 9UUR — 2 kinases

Total number of chains: 2
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 9UURB
All chains
Pymol session (all) Pymol script (all)
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label DFG-Asp_rot_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Asp
χ1,χ2		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK3 MK03_HUMAN 9UURB P27361 26 374 379.0 ANP:60402 ATPlike Inactive DFGin 7.046 16.721 BLAminus DFGAsp-rot-in -125.2774, -171.8504 57.8871, 62.6574 204.6215, -38.0138 -83.9318, 70.2924 271.3877, 98.988 -91.2011, -102.4627 in-out in 9.841 Saltbr-out 3.702 HRD-in -63.3287, -44.4231 65.9337, -2.9097 out-in-out SNCoio in-out ActLoopNT-in 3.31 ActLoopCT-out nonTYR APEdihe_aaioo APEdist_oooo APE10-dihe-na -73.149, 154.5025 APE9-dihe-na -157.2089, 162.6587 APE8-dihe-in -97.0192, 119.1986 APE8-rot-out 59.5672 APE67-dihe-out -91.6183, -7.4904 -122.261, 114.9769 APE12-dist-out 15.931 APE11-dist-out 15.9 APE10-dist-out 18.061 APE9-dist-out 13.143 None None None EM 3.36 999.0 999.0 B 388 349 0 0 0 0 [[42, 330]] 1.0 9uur CMGC_MAPK3_HUMAN CMGC 3.5e-87 298.4 1 301 301 183 184 185 187 189 71 88 92 163 165 164 166 227 214 209 208 207 206 205 204 203 123 Mitogen-activated protein kinase 3
STE MAP2K1 MP2K1_HUMAN 9UURA Q02750 4 379 393.0 ANP:60501 ATPlike Active DFGin 6.227 14.046 BLAminus DFGAsp-rot-in -145.2732, -178.4115 60.1368, 73.8348 164.4819, -15.6135 -89.4006, 20.7227 306.6381, 103.9718 -66.7925, -44.896 in-in in 8.665 Saltbr-in 2.97 HRD-in -65.7872, -45.4895 71.8774, 13.1478 in-in-in SNCiii in-in ActLoopNT-in 3.235 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -131.5144, 1.4418 APE9-dihe-na -79.4285, -172.5974 APE8-dihe-in -96.841, 122.4276 APE8-rot-in 296.3075 APE67-dihe-in -76.6329, -28.5549 -63.1985, -20.7399 APE12-dist-in 8.806 APE11-dist-in 11.202 APE10-dist-in 5.421 APE9-dist-in 4.103 None SEP218,SEP222 SEP218,SEP222 EM 3.36 999.0 999.0 A 403 308 30 0 0 0 [[68, 361]] 1.0 9uur STE_MAP2K1_HUMAN STE 2.7e-97 331.3 1 257 257 207 208 209 211 213 97 114 118 187 189 188 190 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1

PDB: 9UUR — 2 kinases

Total number of chains: 2
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 9UURB
All chains
Pymol session (all) Pymol script (all)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label DFG-Asp_rot_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Asp
χ1,χ2		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK3 MK03_HUMAN 9UURB P27361 26 374 379.0 ANP:60402 ATPlike Inactive DFGin 7.046 16.721 BLAminus DFGAsp-rot-in -125.2774, -171.8504 57.8871, 62.6574 204.6215, -38.0138 -83.9318, 70.2924 271.3877, 98.988 -91.2011, -102.4627 in-out in 9.841 Saltbr-out 3.702 HRD-in -63.3287, -44.4231 65.9337, -2.9097 out-in-out SNCoio in-out ActLoopNT-in 3.31 ActLoopCT-out nonTYR APEdihe_aaioo APEdist_oooo APE10-dihe-na -73.149, 154.5025 APE9-dihe-na -157.2089, 162.6587 APE8-dihe-in -97.0192, 119.1986 APE8-rot-out 59.5672 APE67-dihe-out -91.6183, -7.4904 -122.261, 114.9769 APE12-dist-out 15.931 APE11-dist-out 15.9 APE10-dist-out 18.061 APE9-dist-out 13.143 None None None EM 3.36 999.0 999.0 B 388 349 0 0 0 0 [[42, 330]] 1.0 9uur Homo sapiens CMGC_MAPK3_HUMAN CMGC 3.5e-87 298.4 1 301 301 183 184 185 187 189 71 88 92 163 165 164 166 227 214 209 208 207 206 205 204 203 123 Mitogen-activated protein kinase 3
STE MAP2K1 MP2K1_HUMAN 9UURA Q02750 4 379 393.0 ANP:60501 ATPlike Active DFGin 6.227 14.046 BLAminus DFGAsp-rot-in -145.2732, -178.4115 60.1368, 73.8348 164.4819, -15.6135 -89.4006, 20.7227 306.6381, 103.9718 -66.7925, -44.896 in-in in 8.665 Saltbr-in 2.97 HRD-in -65.7872, -45.4895 71.8774, 13.1478 in-in-in SNCiii in-in ActLoopNT-in 3.235 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -131.5144, 1.4418 APE9-dihe-na -79.4285, -172.5974 APE8-dihe-in -96.841, 122.4276 APE8-rot-in 296.3075 APE67-dihe-in -76.6329, -28.5549 -63.1985, -20.7399 APE12-dist-in 8.806 APE11-dist-in 11.202 APE10-dist-in 5.421 APE9-dist-in 4.103 None SEP218,SEP222 SEP218,SEP222 EM 3.36 999.0 999.0 A 403 308 30 0 0 0 [[68, 361]] 1.0 9uur Homo sapiens STE_MAP2K1_HUMAN STE 2.7e-97 331.3 1 257 257 207 208 209 211 213 97 114 118 187 189 188 190 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1

PDB: 9UUR — 2 kinases

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label DFG-Asp_rot_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Asp
χ1,χ2		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name