PDB: 9NA3 — TKL IRAK4_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 9NA3A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 9NA3A Q9NWZ3 164 458 460.0 A1BWX:501 Type1 Active DFGin 6.752 13.8599 BLAminus -133.1, 172.88 66.49, 85.44 -111.24, 22.95 310.94, 83.55 -69.24, -28.75 in-in in 8.6045 Saltbr-in 3.0051 HRD-in -73.29, -51.42 75.45, 6.3 in-in-in SNCiii in-in ActLoopNT-in 2.9071 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -121.49, 152.01 APE9-dihe-na 139.45, -179.34 APE8-dihe-in -101.95, 112.38 APE8-rot-in 313.22 APE67-dihe-in -64.69, -17.61 -61.03, -33.08 APE12-dist-in 9.927 APE11-dist-in 11.7302 APE10-dist-in 6.4552 APE9-dist-in 4.2549 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.1 0.245 0.277 A 304.0 284.0 11 30 25 5 [[183, 456]] 1.0 9na3 TKL_IRAK4_HUMAN TKL 4.2e-84 288.2 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 9NA3H0A0 Q9NWZ3 164 459 460.0 A1BWX:501 Type1 Active DFGin 6.5887 14.4287 BLAminus -128.39, 175.47 61.09, 89.59 -111.86, 22.39 307.69, 91.01 -72.62, -22.45 in-in in 9.0451 Saltbr-in 3.1983 HRD-in -69.35, -50.66 74.83, 1.0 in-in-in SNCiii in-in ActLoopNT-in 2.7258 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -125.08, 148.29 APE9-dihe-na 138.75, -172.51 APE8-dihe-in -111.34, 119.79 APE8-rot-in 307.77 APE67-dihe-in -65.4, -14.21 -55.78, -41.76 APE12-dist-in 9.9985 APE11-dist-in 11.593 APE10-dist-in 6.0692 APE9-dist-in 4.0699 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.1 0.245 0.277 H0A0 304.0 277.0 19 30 25 5 [[183, 456]] 1.0 9na3 TKL_IRAK4_HUMAN TKL 4.2e-84 288.2 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

PDB: 9NA3 — TKL IRAK4_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 9NA3A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 9NA3A Q9NWZ3 164 458 460.0 A1BWX:501 Type1 Active DFGin 6.752 13.8599 BLAminus -133.1, 172.88 66.49, 85.44 -111.24, 22.95 310.94, 83.55 -69.24, -28.75 in-in in 8.6045 Saltbr-in 3.0051 HRD-in -73.29, -51.42 75.45, 6.3 in-in-in SNCiii in-in ActLoopNT-in 2.9071 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -121.49, 152.01 APE9-dihe-na 139.45, -179.34 APE8-dihe-in -101.95, 112.38 APE8-rot-in 313.22 APE67-dihe-in -64.69, -17.61 -61.03, -33.08 APE12-dist-in 9.927 APE11-dist-in 11.7302 APE10-dist-in 6.4552 APE9-dist-in 4.2549 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.1 0.245 0.277 A 304.0 284.0 11 30 25 5 [[183, 456]] 1.0 9na3 Homo sapiens TKL_IRAK4_HUMAN TKL 4.2e-84 288.2 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 9NA3H0A0 Q9NWZ3 164 459 460.0 A1BWX:501 Type1 Active DFGin 6.5887 14.4287 BLAminus -128.39, 175.47 61.09, 89.59 -111.86, 22.39 307.69, 91.01 -72.62, -22.45 in-in in 9.0451 Saltbr-in 3.1983 HRD-in -69.35, -50.66 74.83, 1.0 in-in-in SNCiii in-in ActLoopNT-in 2.7258 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -125.08, 148.29 APE9-dihe-na 138.75, -172.51 APE8-dihe-in -111.34, 119.79 APE8-rot-in 307.77 APE67-dihe-in -65.4, -14.21 -55.78, -41.76 APE12-dist-in 9.9985 APE11-dist-in 11.593 APE10-dist-in 6.0692 APE9-dist-in 4.0699 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.1 0.245 0.277 H0A0 304.0 277.0 19 30 25 5 [[183, 456]] 1.0 9na3 Homo sapiens TKL_IRAK4_HUMAN TKL 4.2e-84 288.2 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

PDB: 9NA3 — TKL IRAK4_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name