9H8S

CDK8 (Cyclin-dependent kinase 8)
Group: CMGC
Uniprot: CDK8_HUMAN
Organism: Homo sapiens
Domain boundary: 20 - 335
Resolu: 2.157

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A None DFGin BLAminus in-in out-none A1ITF Type1 1 - 362 17
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
         -          9         19         29 
gpmdykdddd kMDYDFKVKL SSERERVEDL FEYEGCKVGR 
        39         49         59         69 
GTYGHVYKAK RKDGKDDKDY ALKQIEGTGI SMSACREIAL 
        79         89         99        109 
LRELKHPNVI SLQKVFLSHA DRKVWLLFDY AEHDLWHIIK 
       119        129        139        149 
FHRASKANkk pvqLPRGMVK SLLYQILDGI HYLHANWVLH 
       159        169        179        189 
RDLKPANILV MGEGPERGRV KIADMGFARl fnsplkplad 
       199        209        219        229 
ldpvvvTFWY RAPELLLGAR HYTKAIDIWA IGCIFAELLT 
       239        249        259        269 
SEPIFHCRQe diktSNPYHH DQLDRIFNVM GFPADKDWED 
       279        289        299        309 
IKKMPEHSTL MKDFRRNTYT NCSLIKYMEK HKVKPDSKAF 
       319        329        339        349 
HLLQKLLTMD PIKRITSEQA MQDPYFLEDP LPTSDVFAGC 
       359        369        379        389 
QIPYPKREFL TEEepddkgd kknqqqqqgn nhtngtghpg 
       399 
nqdsshtqgp plkk
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None