PDB: 8V1O — TKL IRAK4_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 8V1OC
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 8V1OA Q9NWZ3 163 459 460.0 Y9T:501 Type1 Inactive DFGin 6.855 14.248 BLAminus -140.64, 168.57 69.95, 86.27 -108.05, 19.4 305.86, 96.59 -62.38, -30.29 in-out in 8.95 Saltbr-out 4.347 HRD-in -60.57, -58.78 78.86, 6.37 out-in-in SNCoii in-in ActLoopNT-in 2.746 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.84, 152.18 APE9-dihe-na 140.36, 176.78 APE8-dihe-in -102.6, 111.09 APE8-rot-in 311.94 APE67-dihe-in -57.16, -25.0 -36.59, -53.2 APE12-dist-in 9.946 APE11-dist-in 11.778 APE10-dist-in 6.426 APE9-dist-in 3.697 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.92 0.219 0.266 A 327 290 7 0 0 3 [[183, 456]] 1.0 8v1o TKL_IRAK4_HUMAN TKL 5.5e-84 287.8 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8V1OB Q9NWZ3 164 459 460.0 Y9T:501 Type1 Inactive DFGin 6.861 14.298 BLAminus -140.52, 168.93 69.44, 87.06 -107.94, 19.45 305.05, 96.72 -62.6, -30.13 in-out in 8.769 Saltbr-out 3.69 HRD-in -60.51, -59.01 78.22, 6.98 out-in-in SNCoii in-in ActLoopNT-in 2.771 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.06, 153.17 APE9-dihe-na 139.34, 176.48 APE8-dihe-in -102.52, 110.93 APE8-rot-in 310.58 APE67-dihe-in -54.87, -25.59 -38.21, -52.86 APE12-dist-in 10.016 APE11-dist-in 11.689 APE10-dist-in 6.266 APE9-dist-in 3.655 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.92 0.219 0.266 B 327 289 7 0 0 3 [[183, 456]] 1.0 8v1o TKL_IRAK4_HUMAN TKL 5.5e-84 287.8 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8V1OC Q9NWZ3 163 459 460.0 Y9T:501 Type1 Inactive DFGin 6.915 14.164 BLAminus -140.19, 169.04 68.79, 87.36 -108.28, 19.76 305.21, 96.76 -61.62, -32.73 in-out in 8.899 Saltbr-out 4.059 HRD-in -60.61, -59.09 78.04, 8.77 out-in-in SNCoii in-in ActLoopNT-in 2.776 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.34, 152.45 APE9-dihe-na 142.6, 179.16 APE8-dihe-in -102.2, 110.2 APE8-rot-in 311.46 APE67-dihe-in -56.49, -25.16 -38.09, -52.95 APE12-dist-in 9.991 APE11-dist-in 11.525 APE10-dist-in 6.209 APE9-dist-in 3.69 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.92 0.219 0.266 C 327 292 5 0 0 0 [[183, 456]] 1.0 8v1o TKL_IRAK4_HUMAN TKL 5.5e-84 287.8 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8V1OD Q9NWZ3 163 459 460.0 Y9T:501 Type1 Inactive DFGin 6.85 14.268 BLAminus -140.2, 169.66 70.3, 86.25 -107.86, 18.94 306.2, 96.68 -63.07, -30.17 in-out in 8.757 Saltbr-out 4.051 HRD-in -61.84, -59.06 77.97, 8.8 out-in-in SNCoii in-in ActLoopNT-in 2.779 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -133.76, 152.94 APE9-dihe-na 140.97, 176.36 APE8-dihe-in -102.92, 110.82 APE8-rot-in 311.53 APE67-dihe-in -56.93, -25.15 -39.7, -51.03 APE12-dist-in 10.079 APE11-dist-in 11.753 APE10-dist-in 6.401 APE9-dist-in 3.697 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.92 0.219 0.266 D 327 288 9 0 0 5 [[183, 456]] 1.0 8v1o TKL_IRAK4_HUMAN TKL 5.5e-84 287.8 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

PDB: 8V1O — TKL IRAK4_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 8V1OC
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 8V1OA Q9NWZ3 163 459 460.0 Y9T:501 Type1 Inactive DFGin 6.855 14.248 BLAminus -140.64, 168.57 69.95, 86.27 -108.05, 19.4 305.86, 96.59 -62.38, -30.29 in-out in 8.95 Saltbr-out 4.347 HRD-in -60.57, -58.78 78.86, 6.37 out-in-in SNCoii in-in ActLoopNT-in 2.746 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.84, 152.18 APE9-dihe-na 140.36, 176.78 APE8-dihe-in -102.6, 111.09 APE8-rot-in 311.94 APE67-dihe-in -57.16, -25.0 -36.59, -53.2 APE12-dist-in 9.946 APE11-dist-in 11.778 APE10-dist-in 6.426 APE9-dist-in 3.697 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.92 0.219 0.266 A 327 290 7 0 0 3 [[183, 456]] 1.0 8v1o Homo sapiens TKL_IRAK4_HUMAN TKL 5.5e-84 287.8 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8V1OB Q9NWZ3 164 459 460.0 Y9T:501 Type1 Inactive DFGin 6.861 14.298 BLAminus -140.52, 168.93 69.44, 87.06 -107.94, 19.45 305.05, 96.72 -62.6, -30.13 in-out in 8.769 Saltbr-out 3.69 HRD-in -60.51, -59.01 78.22, 6.98 out-in-in SNCoii in-in ActLoopNT-in 2.771 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.06, 153.17 APE9-dihe-na 139.34, 176.48 APE8-dihe-in -102.52, 110.93 APE8-rot-in 310.58 APE67-dihe-in -54.87, -25.59 -38.21, -52.86 APE12-dist-in 10.016 APE11-dist-in 11.689 APE10-dist-in 6.266 APE9-dist-in 3.655 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.92 0.219 0.266 B 327 289 7 0 0 3 [[183, 456]] 1.0 8v1o Homo sapiens TKL_IRAK4_HUMAN TKL 5.5e-84 287.8 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8V1OC Q9NWZ3 163 459 460.0 Y9T:501 Type1 Inactive DFGin 6.915 14.164 BLAminus -140.19, 169.04 68.79, 87.36 -108.28, 19.76 305.21, 96.76 -61.62, -32.73 in-out in 8.899 Saltbr-out 4.059 HRD-in -60.61, -59.09 78.04, 8.77 out-in-in SNCoii in-in ActLoopNT-in 2.776 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.34, 152.45 APE9-dihe-na 142.6, 179.16 APE8-dihe-in -102.2, 110.2 APE8-rot-in 311.46 APE67-dihe-in -56.49, -25.16 -38.09, -52.95 APE12-dist-in 9.991 APE11-dist-in 11.525 APE10-dist-in 6.209 APE9-dist-in 3.69 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.92 0.219 0.266 C 327 292 5 0 0 0 [[183, 456]] 1.0 8v1o Homo sapiens TKL_IRAK4_HUMAN TKL 5.5e-84 287.8 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8V1OD Q9NWZ3 163 459 460.0 Y9T:501 Type1 Inactive DFGin 6.85 14.268 BLAminus -140.2, 169.66 70.3, 86.25 -107.86, 18.94 306.2, 96.68 -63.07, -30.17 in-out in 8.757 Saltbr-out 4.051 HRD-in -61.84, -59.06 77.97, 8.8 out-in-in SNCoii in-in ActLoopNT-in 2.779 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -133.76, 152.94 APE9-dihe-na 140.97, 176.36 APE8-dihe-in -102.92, 110.82 APE8-rot-in 311.53 APE67-dihe-in -56.93, -25.15 -39.7, -51.03 APE12-dist-in 10.079 APE11-dist-in 11.753 APE10-dist-in 6.401 APE9-dist-in 3.697 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.92 0.219 0.266 D 327 288 9 0 0 5 [[183, 456]] 1.0 8v1o Homo sapiens TKL_IRAK4_HUMAN TKL 5.5e-84 287.8 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

PDB: 8V1O — TKL IRAK4_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name