8UWN

CLK1 (Dual specificity protein kinase CLK1)
Group: CMGC
Uniprot: CLK1_HUMAN
Organism: Homo sapiens
Domain boundary: 161 - 477
Resolu: 1.8

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A None DFGin BLAminus in-in in-none XQX Type1 148 - 482 0
Representative sequence - Chain A
- - 154 164
mhhhhhhssg vdlgtenlyf qsmHLICQSG DVLSARYEIV
174 184 194 204
DTLGEGAFGK VVECIDHKAG GRHVAVKIVK NVDRYCEAAR
214 224 234 244
SEIQVLEHLN TTDPNSTFRC VQMLEWFEHH GHICIVFELL
254 264 274 284
GLSTYDFIKE NGFLPFRLDH IRKMAYQICK SVNFLHSNKL
294 304 314 324
THTDLKPENI LFVQSDYTEA YNPKIKRDER TLINPDIKVV
334 344 354 364
DFGSATYDDE HHSTLVSTRH YRAPEVILAL GWSQPCDVWS
374 384 394 404
IGCILIEYYL GFTVFPTHDS KEHLAMMERI LGPLPKHMIQ
414 424 434 444
KTRKRKYFHH DRLDWDEHSS AGRYVSRACK PLKEFMLSQD
454 464 474 484
VEHERLFDLI QKMLEYDPAK RITLREALKH PFFDLLKKsi


Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X341,X342