| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AGC | PRKACA | KAPCA_MOUSE | 8UKND | P05132 | 16 | 351 | 351.0 | ANP:60400 | ATPlike | Inactive | DFGin | 6.6105 | 14.9582 | ABAminus | -121.75, -47.3 | -93.55, 119.31 | -121.12, 22.25 | 288.77, 83.91 | -60.17, -43.74 | in-out | in | 9.6363 | Saltbr-out | 4.003 | HRD-in | -71.48, -47.99 | 39.7, 38.93 | out-in-in | SNCoii | in-in | ActLoopNT-in | 2.9756 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -150.1, 161.55 | APE9-dihe-na | 104.53, 169.82 | APE8-dihe-in | -72.88, 137.25 | APE8-rot-in | 280.42 | APE67-dihe-in | -60.56, -25.71 | -55.68, -37.9 | APE12-dist-in | 8.0946 | APE11-dist-in | 11.2355 | APE10-dist-in | 5.8091 | APE9-dist-in | 4.6921 | None | SEP140,TPO198,SEP339 | SEP140,TPO198,SEP339 | XRAY | 2.75 | 0.197 | 0.232 | D | 339.0 | 323.0 | 0 | 25 | 25 | 0 | [[44, 298]] | 1.0 | 8ukn | Mus musculus | AGC_PRKACA_MOUSE | AGC | 1.3e-94 | 322.1 | 1.0 | 260.0 | 260.0 | 184 | 185 | 186 | 188 | 190 | 73 | 92 | 96 | 164 | 166 | 165 | 167.0 | 221 | 209 | 204 | 203 | 202 | 201 | 200 | 199 | 198 | 122 | cAMP-dependent protein kinase catalytic subunit alpha |
| AGC | PRKACA | KAPCA_MOUSE | 8UKNC | P05132 | 16 | 351 | 351.0 | No_ligand | No_ligand | Inactive | DFGin | 6.9773 | 15.8143 | ABAminus | -121.28, -46.06 | -94.44, 119.11 | -121.88, 20.98 | 289.09, 82.99 | -60.59, -43.51 | out-out | out | 10.2655 | Saltbr-out | 3.7763 | HRD-in | -69.49, -46.7 | 40.24, 37.27 | out-in-in | SNCoii | in-in | ActLoopNT-in | 2.8604 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -152.14, 161.55 | APE9-dihe-na | 102.26, 166.3 | APE8-dihe-in | -75.0, 136.39 | APE8-rot-in | 285.29 | APE67-dihe-in | -59.55, -25.47 | -55.27, -37.71 | APE12-dist-in | 8.2631 | APE11-dist-in | 11.3425 | APE10-dist-in | 5.8906 | APE9-dist-in | 4.4404 | None | SEP140,TPO198,SEP339 | SEP140,TPO198,SEP339 | XRAY | 2.75 | 0.197 | 0.232 | C | 339.0 | 323.0 | 0 | 25 | 25 | 0 | [[44, 298]] | 1.0 | 8ukn | Mus musculus | AGC_PRKACA_MOUSE | AGC | 1.3e-94 | 322.1 | 1.0 | 260.0 | 260.0 | 184 | 185 | 186 | 188 | 190 | 73 | 92 | 96 | 164 | 166 | 165 | 167.0 | 221 | 209 | 204 | 203 | 202 | 201 | 200 | 199 | 198 | 122 | cAMP-dependent protein kinase catalytic subunit alpha |
| AGC | PRKACA | KAPCA_MOUSE | 8UKNF | P05132 | 16 | 351 | 351.0 | No_ligand | No_ligand | Inactive | DFGin | 6.8893 | 15.4858 | ABAminus | -119.02, -48.36 | -94.42, 119.64 | -122.07, 21.3 | 289.06, 84.07 | -60.37, -43.79 | in-none | in | 9.9681 | Saltbr-none | 999.0 | HRD-in | -70.24, -47.3 | 40.22, 39.45 | none-in-out | SNCnio | in-out | ActLoopNT-in | 3.1956 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_iiii | APE10-dihe-na | -150.61, 160.97 | APE9-dihe-na | 102.69, 167.59 | APE8-dihe-in | -73.59, 140.15 | APE8-rot-out | 204.21 | APE67-dihe-in | -61.18, -25.59 | -54.92, -37.71 | APE12-dist-in | 8.0636 | APE11-dist-in | 11.1851 | APE10-dist-in | 5.795 | APE9-dist-in | 4.6032 | None | SEP140,TPO198,SEP339 | SEP140,TPO198,SEP339 | XRAY | 2.75 | 0.197 | 0.232 | F | 339.0 | 323.0 | 0 | 25 | 25 | 0 | [[44, 298]] | 1.0 | 8ukn | Mus musculus | AGC_PRKACA_MOUSE | AGC | 1.3e-94 | 322.1 | 1.0 | 260.0 | 260.0 | 184 | 185 | 186 | 188 | 190 | 73 | 92 | 96 | 164 | 166 | 165 | 167.0 | 221 | 209 | 204 | 203 | 202 | 201 | 200 | 199 | 198 | 122 | cAMP-dependent protein kinase catalytic subunit alpha |
| AGC | PRKACA | KAPCA_MOUSE | 8UKNH | P05132 | 16 | 351 | 351.0 | No_ligand | No_ligand | Inactive | DFGin | 6.9904 | 15.9406 | ABAminus | -119.65, -47.17 | -95.12, 119.59 | -123.41, 20.33 | 289.47, 82.92 | -60.29, -43.54 | out-out | out | 10.3777 | Saltbr-out | 4.1022 | HRD-in | -70.28, -46.9 | 40.49, 37.83 | out-in-in | SNCoii | in-in | ActLoopNT-in | 2.9436 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -151.73, 160.95 | APE9-dihe-na | 102.27, 168.23 | APE8-dihe-in | -75.08, 137.2 | APE8-rot-in | 283.98 | APE67-dihe-in | -59.99, -25.87 | -55.81, -37.99 | APE12-dist-in | 8.247 | APE11-dist-in | 11.3303 | APE10-dist-in | 5.9313 | APE9-dist-in | 4.5321 | None | SEP140,TPO198,SEP339 | SEP140,TPO198,SEP339 | XRAY | 2.75 | 0.197 | 0.232 | H | 339.0 | 325.0 | 0 | 25 | 25 | 0 | [[44, 298]] | 1.0 | 8ukn | Mus musculus | AGC_PRKACA_MOUSE | AGC | 1.3e-94 | 322.1 | 1.0 | 260.0 | 260.0 | 184 | 185 | 186 | 188 | 190 | 73 | 92 | 96 | 164 | 166 | 165 | 167.0 | 221 | 209 | 204 | 203 | 202 | 201 | 200 | 199 | 198 | 122 | cAMP-dependent protein kinase catalytic subunit alpha |
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AGC | PRKACA | KAPCA_MOUSE | 8UKND | P05132 | 16 | 351 | 351.0 | ANP:60400 | ATPlike | Inactive | DFGin | 6.6105 | 14.9582 | ABAminus | -121.75, -47.3 | -93.55, 119.31 | -121.12, 22.25 | 288.77, 83.91 | -60.17, -43.74 | in-out | in | 9.6363 | Saltbr-out | 4.003 | HRD-in | -71.48, -47.99 | 39.7, 38.93 | out-in-in | SNCoii | in-in | ActLoopNT-in | 2.9756 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -150.1, 161.55 | APE9-dihe-na | 104.53, 169.82 | APE8-dihe-in | -72.88, 137.25 | APE8-rot-in | 280.42 | APE67-dihe-in | -60.56, -25.71 | -55.68, -37.9 | APE12-dist-in | 8.0946 | APE11-dist-in | 11.2355 | APE10-dist-in | 5.8091 | APE9-dist-in | 4.6921 | None | SEP140,TPO198,SEP339 | SEP140,TPO198,SEP339 | XRAY | 2.75 | 0.197 | 0.232 | D | 339.0 | 323.0 | 0 | 25 | 25 | 0 | [[44, 298]] | 1.0 | 8ukn | Mus musculus | AGC_PRKACA_MOUSE | AGC | 1.3e-94 | 322.1 | 1.0 | 260.0 | 260.0 | 184 | 185 | 186 | 188 | 190 | 73 | 92 | 96 | 164 | 166 | 165 | 167.0 | 221 | 209 | 204 | 203 | 202 | 201 | 200 | 199 | 198 | 122 | cAMP-dependent protein kinase catalytic subunit alpha |
| AGC | PRKACA | KAPCA_MOUSE | 8UKNC | P05132 | 16 | 351 | 351.0 | No_ligand | No_ligand | Inactive | DFGin | 6.9773 | 15.8143 | ABAminus | -121.28, -46.06 | -94.44, 119.11 | -121.88, 20.98 | 289.09, 82.99 | -60.59, -43.51 | out-out | out | 10.2655 | Saltbr-out | 3.7763 | HRD-in | -69.49, -46.7 | 40.24, 37.27 | out-in-in | SNCoii | in-in | ActLoopNT-in | 2.8604 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -152.14, 161.55 | APE9-dihe-na | 102.26, 166.3 | APE8-dihe-in | -75.0, 136.39 | APE8-rot-in | 285.29 | APE67-dihe-in | -59.55, -25.47 | -55.27, -37.71 | APE12-dist-in | 8.2631 | APE11-dist-in | 11.3425 | APE10-dist-in | 5.8906 | APE9-dist-in | 4.4404 | None | SEP140,TPO198,SEP339 | SEP140,TPO198,SEP339 | XRAY | 2.75 | 0.197 | 0.232 | C | 339.0 | 323.0 | 0 | 25 | 25 | 0 | [[44, 298]] | 1.0 | 8ukn | Mus musculus | AGC_PRKACA_MOUSE | AGC | 1.3e-94 | 322.1 | 1.0 | 260.0 | 260.0 | 184 | 185 | 186 | 188 | 190 | 73 | 92 | 96 | 164 | 166 | 165 | 167.0 | 221 | 209 | 204 | 203 | 202 | 201 | 200 | 199 | 198 | 122 | cAMP-dependent protein kinase catalytic subunit alpha |
| AGC | PRKACA | KAPCA_MOUSE | 8UKNF | P05132 | 16 | 351 | 351.0 | No_ligand | No_ligand | Inactive | DFGin | 6.8893 | 15.4858 | ABAminus | -119.02, -48.36 | -94.42, 119.64 | -122.07, 21.3 | 289.06, 84.07 | -60.37, -43.79 | in-none | in | 9.9681 | Saltbr-none | 999.0 | HRD-in | -70.24, -47.3 | 40.22, 39.45 | none-in-out | SNCnio | in-out | ActLoopNT-in | 3.1956 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_iiii | APE10-dihe-na | -150.61, 160.97 | APE9-dihe-na | 102.69, 167.59 | APE8-dihe-in | -73.59, 140.15 | APE8-rot-out | 204.21 | APE67-dihe-in | -61.18, -25.59 | -54.92, -37.71 | APE12-dist-in | 8.0636 | APE11-dist-in | 11.1851 | APE10-dist-in | 5.795 | APE9-dist-in | 4.6032 | None | SEP140,TPO198,SEP339 | SEP140,TPO198,SEP339 | XRAY | 2.75 | 0.197 | 0.232 | F | 339.0 | 323.0 | 0 | 25 | 25 | 0 | [[44, 298]] | 1.0 | 8ukn | Mus musculus | AGC_PRKACA_MOUSE | AGC | 1.3e-94 | 322.1 | 1.0 | 260.0 | 260.0 | 184 | 185 | 186 | 188 | 190 | 73 | 92 | 96 | 164 | 166 | 165 | 167.0 | 221 | 209 | 204 | 203 | 202 | 201 | 200 | 199 | 198 | 122 | cAMP-dependent protein kinase catalytic subunit alpha |
| AGC | PRKACA | KAPCA_MOUSE | 8UKNH | P05132 | 16 | 351 | 351.0 | No_ligand | No_ligand | Inactive | DFGin | 6.9904 | 15.9406 | ABAminus | -119.65, -47.17 | -95.12, 119.59 | -123.41, 20.33 | 289.47, 82.92 | -60.29, -43.54 | out-out | out | 10.3777 | Saltbr-out | 4.1022 | HRD-in | -70.28, -46.9 | 40.49, 37.83 | out-in-in | SNCoii | in-in | ActLoopNT-in | 2.9436 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -151.73, 160.95 | APE9-dihe-na | 102.27, 168.23 | APE8-dihe-in | -75.08, 137.2 | APE8-rot-in | 283.98 | APE67-dihe-in | -59.99, -25.87 | -55.81, -37.99 | APE12-dist-in | 8.247 | APE11-dist-in | 11.3303 | APE10-dist-in | 5.9313 | APE9-dist-in | 4.5321 | None | SEP140,TPO198,SEP339 | SEP140,TPO198,SEP339 | XRAY | 2.75 | 0.197 | 0.232 | H | 339.0 | 325.0 | 0 | 25 | 25 | 0 | [[44, 298]] | 1.0 | 8ukn | Mus musculus | AGC_PRKACA_MOUSE | AGC | 1.3e-94 | 322.1 | 1.0 | 260.0 | 260.0 | 184 | 185 | 186 | 188 | 190 | 73 | 92 | 96 | 164 | 166 | 165 | 167.0 | 221 | 209 | 204 | 203 | 202 | 201 | 200 | 199 | 198 | 122 | cAMP-dependent protein kinase catalytic subunit alpha |