PDB: 8TO3 — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 50.0% 8TO3A
DFGin BLBtrans 2 50.0% 8TO3D
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 8TO3B P00533 702 1014 1210.0 ANP:1102 ATPlike Inactive DFGin 3.6573 14.9344 BLBplus -134.55, 162.66 68.08, 49.36 -93.73, 164.43 101.15, 105.54 56.1, 2.84 out-out out 13.7673 Saltbr-out 13.9706 HRD-in -68.15, -46.1 73.95, -11.19 out-out-out SNCooo out-out ActLoopNT-out 6.8421 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 106.24 APE8-dihe-in -74.12, 71.61 APE8-rot-na 27.49 APE67-dihe-in -65.2, -1.6 -53.66, -41.57 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.1295 T790M,V948R None None XRAY 2.49 0.231 0.269 B 328.0 291.0 18 30 17 13 [[712, 970]] 1.0 8to3 TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8TO3A P00533 702 1007 1210.0 IXC:1101 Type1.5_Front Inactive DFGin 4.3713 13.9959 BLBplus -135.94, 169.11 67.48, 22.01 -70.94, 138.5 62.13, 97.63 90.56, 75.28 out-out out 13.4823 Saltbr-out 16.4323 HRD-in -64.1, -62.98 87.72, -19.67 out-out-out SNCooo out-out ActLoopNT-out 8.6669 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 121.18 APE8-dihe-in -84.44, 67.85 APE8-rot-na 34.08 APE67-dihe-in -75.79, -1.46 -59.58, -38.97 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.4917 T790M,V948R None None XRAY 2.49 0.231 0.269 A 328.0 291.0 15 30 15 15 [[712, 970]] 1.0 8to3 TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8TO3C P00533 702 1014 1210.0 ANP:1102 ATPlike Inactive DFGin 5.7531 16.5332 BLBtrans -133.38, -174.65 59.98, 24.74 -65.74, 136.64 157.32, 80.88 79.44, -13.7 out-out out 13.6547 Saltbr-out 13.5313 HRD-in -66.43, -56.05 80.37, -11.56 out-out-out SNCooo out-out ActLoopNT-out 6.3729 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 117.97 APE8-dihe-in -84.11, 59.51 APE8-rot-na 29.31 APE67-dihe-in -74.18, -0.3 -51.78, -42.05 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.1735 T790M,V948R None None XRAY 2.49 0.231 0.269 C 328.0 295.0 16 30 17 13 [[712, 970]] 1.0 8to3 TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8TO3D P00533 702 1008 1210.0 ANP:1102 ATPlike Inactive DFGin 6.2656 16.7122 BLBtrans -127.69, 172.31 68.6, 30.15 -69.25, 140.14 165.75, 69.84 67.25, -4.22 out-out out 14.3859 Saltbr-out 13.1993 HRD-in -68.61, -53.44 82.24, -15.94 out-out-out SNCooo out-out ActLoopNT-out 6.5519 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 120.24 APE8-dihe-in -79.84, 75.73 APE8-rot-na 31.27 APE67-dihe-in -78.58, -0.75 -60.94, -39.18 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.144 T790M,V948R None None XRAY 2.49 0.231 0.269 D 328.0 293.0 14 30 17 13 [[712, 970]] 1.0 8to3 TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 8TO3 — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 50.0% 8TO3A
DFGin BLBtrans 2 50.0% 8TO3D
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 8TO3B P00533 702 1014 1210.0 ANP:1102 ATPlike Inactive DFGin 3.6573 14.9344 BLBplus -134.55, 162.66 68.08, 49.36 -93.73, 164.43 101.15, 105.54 56.1, 2.84 out-out out 13.7673 Saltbr-out 13.9706 HRD-in -68.15, -46.1 73.95, -11.19 out-out-out SNCooo out-out ActLoopNT-out 6.8421 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 106.24 APE8-dihe-in -74.12, 71.61 APE8-rot-na 27.49 APE67-dihe-in -65.2, -1.6 -53.66, -41.57 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.1295 T790M,V948R None None XRAY 2.49 0.231 0.269 B 328.0 291.0 18 30 17 13 [[712, 970]] 1.0 8to3 Homo sapiens TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8TO3A P00533 702 1007 1210.0 IXC:1101 Type1.5_Front Inactive DFGin 4.3713 13.9959 BLBplus -135.94, 169.11 67.48, 22.01 -70.94, 138.5 62.13, 97.63 90.56, 75.28 out-out out 13.4823 Saltbr-out 16.4323 HRD-in -64.1, -62.98 87.72, -19.67 out-out-out SNCooo out-out ActLoopNT-out 8.6669 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 121.18 APE8-dihe-in -84.44, 67.85 APE8-rot-na 34.08 APE67-dihe-in -75.79, -1.46 -59.58, -38.97 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.4917 T790M,V948R None None XRAY 2.49 0.231 0.269 A 328.0 291.0 15 30 15 15 [[712, 970]] 1.0 8to3 Homo sapiens TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8TO3C P00533 702 1014 1210.0 ANP:1102 ATPlike Inactive DFGin 5.7531 16.5332 BLBtrans -133.38, -174.65 59.98, 24.74 -65.74, 136.64 157.32, 80.88 79.44, -13.7 out-out out 13.6547 Saltbr-out 13.5313 HRD-in -66.43, -56.05 80.37, -11.56 out-out-out SNCooo out-out ActLoopNT-out 6.3729 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 117.97 APE8-dihe-in -84.11, 59.51 APE8-rot-na 29.31 APE67-dihe-in -74.18, -0.3 -51.78, -42.05 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.1735 T790M,V948R None None XRAY 2.49 0.231 0.269 C 328.0 295.0 16 30 17 13 [[712, 970]] 1.0 8to3 Homo sapiens TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8TO3D P00533 702 1008 1210.0 ANP:1102 ATPlike Inactive DFGin 6.2656 16.7122 BLBtrans -127.69, 172.31 68.6, 30.15 -69.25, 140.14 165.75, 69.84 67.25, -4.22 out-out out 14.3859 Saltbr-out 13.1993 HRD-in -68.61, -53.44 82.24, -15.94 out-out-out SNCooo out-out ActLoopNT-out 6.5519 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 120.24 APE8-dihe-in -79.84, 75.73 APE8-rot-na 31.27 APE67-dihe-in -78.58, -0.75 -60.94, -39.18 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.144 T790M,V948R None None XRAY 2.49 0.231 0.269 D 328.0 293.0 14 30 17 13 [[712, 970]] 1.0 8to3 Homo sapiens TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 8TO3 — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name