| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | BTK | BTK_MOUSE | 8S9FA | P35991 | 392 | 659 | 659.0 | 1N1:801 | Type1 | Inactive | DFGinter | 9.7383 | 8.4773 | BABtrans | -103.75, 162.9 | -98.62, -12.56 | -74.46, 134.73 | 203.6, 82.29 | 75.53, 30.46 | out-out | out | 11.3245 | Saltbr-out | 8.457 | HRD-out | -78.16, 120.76 | -71.26, -27.71 | out-out-none | SNCoon | out-none | ActLoopNT-out | 5.4638 | ActLoopCT-none | TYR | APEdihe_nnnai | APEdist_aaan | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 999.0 | APE8-dihe-none | 999.0, 89.3 | APE8-rot-na | 354.27 | APE67-dihe-in | -88.28, 1.83 | -66.03, -37.53 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-none | 999.0 | L390G,Y551E,Y617P | None | None | XRAY | 2.6 | 0.244 | 0.284 | A | 279.0 | 254.0 | 14 | 29 | 15 | 14 | [[402, 653]] | 1.0 | 8s9f | Mus musculus | TYR_BTK_MOUSE | TYR | 1.3e-92 | 315.7 | 1.0 | 258.0 | 258.0 | 538 | 539 | 540 | 542 | 544 | 430 | 445 | 449 | 518 | 520 | 519 | 521.0 | 579 | 567 | 562 | 561 | 560 | 559 | 558 | 557 | 556 | 475 | Tyrosine-protein kinase BTK |
| TYR | BTK | BTK_MOUSE | 8S9FB | P35991 | 392 | 659 | 659.0 | 1N1:801 | Type1 | Inactive | DFGinter | 9.5087 | 8.4716 | BABtrans | -108.61, 149.63 | -109.15, 7.92 | -82.22, 131.91 | 185.43, 98.64 | 78.7, 27.48 | out-out | out | 11.0192 | Saltbr-out | 10.3295 | HRD-out | -91.58, 112.75 | -69.14, -29.29 | out-out-out | SNCooo | out-out | ActLoopNT-out | 5.6813 | ActLoopCT-out | TYR | APEdihe_niiai | APEdist_aaao | APE10-dihe-none | 999.0, 166.92 | APE9-dihe-in | -91.32, 115.75 | APE8-dihe-in | -71.7, 107.6 | APE8-rot-na | 25.58 | APE67-dihe-in | -83.25, -12.58 | -54.13, -30.99 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 16.1492 | APE9-dist-out | 18.604 | L390G,Y551E,Y617P | None | None | XRAY | 2.6 | 0.244 | 0.284 | B | 279.0 | 255.0 | 13 | 29 | 17 | 12 | [[402, 653]] | 1.0 | 8s9f | Mus musculus | TYR_BTK_MOUSE | TYR | 1.3e-92 | 315.7 | 1.0 | 258.0 | 258.0 | 538 | 539 | 540 | 542 | 544 | 430 | 445 | 449 | 518 | 520 | 519 | 521.0 | 579 | 567 | 562 | 561 | 560 | 559 | 558 | 557 | 556 | 475 | Tyrosine-protein kinase BTK |
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | BTK | BTK_MOUSE | 8S9FA | P35991 | 392 | 659 | 659.0 | 1N1:801 | Type1 | Inactive | DFGinter | 9.7383 | 8.4773 | BABtrans | -103.75, 162.9 | -98.62, -12.56 | -74.46, 134.73 | 203.6, 82.29 | 75.53, 30.46 | out-out | out | 11.3245 | Saltbr-out | 8.457 | HRD-out | -78.16, 120.76 | -71.26, -27.71 | out-out-none | SNCoon | out-none | ActLoopNT-out | 5.4638 | ActLoopCT-none | TYR | APEdihe_nnnai | APEdist_aaan | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 999.0 | APE8-dihe-none | 999.0, 89.3 | APE8-rot-na | 354.27 | APE67-dihe-in | -88.28, 1.83 | -66.03, -37.53 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-none | 999.0 | L390G,Y551E,Y617P | None | None | XRAY | 2.6 | 0.244 | 0.284 | A | 279.0 | 254.0 | 14 | 29 | 15 | 14 | [[402, 653]] | 1.0 | 8s9f | Mus musculus | TYR_BTK_MOUSE | TYR | 1.3e-92 | 315.7 | 1.0 | 258.0 | 258.0 | 538 | 539 | 540 | 542 | 544 | 430 | 445 | 449 | 518 | 520 | 519 | 521.0 | 579 | 567 | 562 | 561 | 560 | 559 | 558 | 557 | 556 | 475 | Tyrosine-protein kinase BTK |
| TYR | BTK | BTK_MOUSE | 8S9FB | P35991 | 392 | 659 | 659.0 | 1N1:801 | Type1 | Inactive | DFGinter | 9.5087 | 8.4716 | BABtrans | -108.61, 149.63 | -109.15, 7.92 | -82.22, 131.91 | 185.43, 98.64 | 78.7, 27.48 | out-out | out | 11.0192 | Saltbr-out | 10.3295 | HRD-out | -91.58, 112.75 | -69.14, -29.29 | out-out-out | SNCooo | out-out | ActLoopNT-out | 5.6813 | ActLoopCT-out | TYR | APEdihe_niiai | APEdist_aaao | APE10-dihe-none | 999.0, 166.92 | APE9-dihe-in | -91.32, 115.75 | APE8-dihe-in | -71.7, 107.6 | APE8-rot-na | 25.58 | APE67-dihe-in | -83.25, -12.58 | -54.13, -30.99 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 16.1492 | APE9-dist-out | 18.604 | L390G,Y551E,Y617P | None | None | XRAY | 2.6 | 0.244 | 0.284 | B | 279.0 | 255.0 | 13 | 29 | 17 | 12 | [[402, 653]] | 1.0 | 8s9f | Mus musculus | TYR_BTK_MOUSE | TYR | 1.3e-92 | 315.7 | 1.0 | 258.0 | 258.0 | 538 | 539 | 540 | 542 | 544 | 430 | 445 | 449 | 518 | 520 | 519 | 521.0 | 579 | 567 | 562 | 561 | 560 | 559 | 558 | 557 | 556 | 475 | Tyrosine-protein kinase BTK |