PDB: 8S17 — TYR KIT_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 2 100.0% 8S17A

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR KIT KIT_HUMAN 8S17A P10721 567 931 976.0 0LI:61001 Type2 Inactive DFGout 15.4253 9.9509 BBAminus -145.25, 179.39 -143.98, 106.64 -67.34, -40.16 274.67, 96.68 58.73, -115.03 in-in in 7.749 Saltbr-in 2.6955 HRD-in -73.68, -54.05 81.88, -13.47 in-out-in SNCioi out-in ActLoopNT-out 16.3106 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -118.0, 112.95 APE9-dihe-in -124.02, 150.83 APE8-dihe-in -80.03, 74.01 APE8-rot-na 32.18 APE67-dihe-in -67.91, -14.83 -61.86, -40.28 APE12-dist-na 16.635 APE11-dist-na 13.2018 APE10-dist-na 11.5146 APE9-dist-in 7.7012 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 2.2 0.203 0.228 A 327.0 287.0 0 30 30 0 [[589, 926]] 1.0 8s17 TYR_KIT_HUMAN TYR 2.3e-104 354.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8S17B P10721 578 931 976.0 0LI:61001 Type2 Inactive DFGout 15.2272 9.8787 BBAminus -145.11, 172.96 -138.62, 103.76 -65.65, -38.27 276.93, 92.02 61.53, -118.4 in-in in 7.6517 Saltbr-in 2.7434 HRD-in -69.78, -55.3 82.77, -9.47 in-out-in SNCioi out-in ActLoopNT-out 16.4084 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -113.26, 116.47 APE9-dihe-in -128.18, 149.58 APE8-dihe-in -80.46, 72.63 APE8-rot-na 32.73 APE67-dihe-in -67.64, -17.39 -58.96, -38.89 APE12-dist-na 16.5047 APE11-dist-na 13.3085 APE10-dist-na 11.7177 APE9-dist-in 7.9746 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 2.2 0.203 0.228 B 327.0 276.0 0 30 30 0 [[589, 926]] 1.0 8s17 TYR_KIT_HUMAN TYR 2.3e-104 354.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit

PDB: 8S17 — TYR KIT_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 2 100.0% 8S17A

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR KIT KIT_HUMAN 8S17A P10721 567 931 976.0 0LI:61001 Type2 Inactive DFGout 15.4253 9.9509 BBAminus -145.25, 179.39 -143.98, 106.64 -67.34, -40.16 274.67, 96.68 58.73, -115.03 in-in in 7.749 Saltbr-in 2.6955 HRD-in -73.68, -54.05 81.88, -13.47 in-out-in SNCioi out-in ActLoopNT-out 16.3106 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -118.0, 112.95 APE9-dihe-in -124.02, 150.83 APE8-dihe-in -80.03, 74.01 APE8-rot-na 32.18 APE67-dihe-in -67.91, -14.83 -61.86, -40.28 APE12-dist-na 16.635 APE11-dist-na 13.2018 APE10-dist-na 11.5146 APE9-dist-in 7.7012 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 2.2 0.203 0.228 A 327.0 287.0 0 30 30 0 [[589, 926]] 1.0 8s17 Homo sapiens TYR_KIT_HUMAN TYR 2.3e-104 354.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8S17B P10721 578 931 976.0 0LI:61001 Type2 Inactive DFGout 15.2272 9.8787 BBAminus -145.11, 172.96 -138.62, 103.76 -65.65, -38.27 276.93, 92.02 61.53, -118.4 in-in in 7.6517 Saltbr-in 2.7434 HRD-in -69.78, -55.3 82.77, -9.47 in-out-in SNCioi out-in ActLoopNT-out 16.4084 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -113.26, 116.47 APE9-dihe-in -128.18, 149.58 APE8-dihe-in -80.46, 72.63 APE8-rot-na 32.73 APE67-dihe-in -67.64, -17.39 -58.96, -38.89 APE12-dist-na 16.5047 APE11-dist-na 13.3085 APE10-dist-na 11.7177 APE9-dist-in 7.9746 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 2.2 0.203 0.228 B 327.0 276.0 0 30 30 0 [[589, 926]] 1.0 8s17 Homo sapiens TYR_KIT_HUMAN TYR 2.3e-104 354.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit

PDB: 8S17 — TYR KIT_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name