PDB: 8S16 — TYR KIT_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 2 100.0% 8S16A

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR KIT KIT_HUMAN 8S16A P10721 566 932 976.0 STI:61001 Type2 Inactive DFGout 16.1561 10.6327 BBAminus -135.66, -175.47 -146.5, 109.21 -66.07, -39.1 278.01, 69.44 60.83, -124.1 in-in in 7.9119 Saltbr-in 2.9645 HRD-in -69.14, -53.88 78.27, -9.6 in-out-in SNCioi out-in ActLoopNT-out 16.0214 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -116.16, 109.76 APE9-dihe-in -124.4, 150.42 APE8-dihe-in -79.68, 69.89 APE8-rot-na 33.56 APE67-dihe-in -69.51, -13.06 -61.98, -37.06 APE12-dist-na 16.4365 APE11-dist-na 13.1795 APE10-dist-na 11.1209 APE9-dist-in 7.7908 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 1.85 0.177 0.207 A 327.0 289.0 0 30 30 0 [[589, 926]] 1.0 8s16 TYR_KIT_HUMAN TYR 2.3e-104 354.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8S16B P10721 578 931 976.0 STI:61001 Type2 Inactive DFGout 15.8879 10.5227 BBAminus -137.35, -173.79 -154.74, 102.74 -60.21, -39.63 280.81, 66.69 55.03, -114.07 in-in in 7.8423 Saltbr-in 2.8528 HRD-in -70.27, -58.28 86.53, -13.22 in-out-in SNCioi out-in ActLoopNT-out 16.1216 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -117.71, 104.25 APE9-dihe-in -123.97, 149.57 APE8-dihe-in -79.76, 65.91 APE8-rot-na 34.81 APE67-dihe-in -69.88, -14.71 -57.96, -38.02 APE12-dist-na 17.0837 APE11-dist-na 13.8991 APE10-dist-na 11.4361 APE9-dist-in 7.9103 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 1.85 0.177 0.207 B 327.0 276.0 0 30 30 0 [[589, 926]] 1.0 8s16 TYR_KIT_HUMAN TYR 2.3e-104 354.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit

PDB: 8S16 — TYR KIT_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 2 100.0% 8S16A

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR KIT KIT_HUMAN 8S16A P10721 566 932 976.0 STI:61001 Type2 Inactive DFGout 16.1561 10.6327 BBAminus -135.66, -175.47 -146.5, 109.21 -66.07, -39.1 278.01, 69.44 60.83, -124.1 in-in in 7.9119 Saltbr-in 2.9645 HRD-in -69.14, -53.88 78.27, -9.6 in-out-in SNCioi out-in ActLoopNT-out 16.0214 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -116.16, 109.76 APE9-dihe-in -124.4, 150.42 APE8-dihe-in -79.68, 69.89 APE8-rot-na 33.56 APE67-dihe-in -69.51, -13.06 -61.98, -37.06 APE12-dist-na 16.4365 APE11-dist-na 13.1795 APE10-dist-na 11.1209 APE9-dist-in 7.7908 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 1.85 0.177 0.207 A 327.0 289.0 0 30 30 0 [[589, 926]] 1.0 8s16 Homo sapiens TYR_KIT_HUMAN TYR 2.3e-104 354.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8S16B P10721 578 931 976.0 STI:61001 Type2 Inactive DFGout 15.8879 10.5227 BBAminus -137.35, -173.79 -154.74, 102.74 -60.21, -39.63 280.81, 66.69 55.03, -114.07 in-in in 7.8423 Saltbr-in 2.8528 HRD-in -70.27, -58.28 86.53, -13.22 in-out-in SNCioi out-in ActLoopNT-out 16.1216 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -117.71, 104.25 APE9-dihe-in -123.97, 149.57 APE8-dihe-in -79.76, 65.91 APE8-rot-na 34.81 APE67-dihe-in -69.88, -14.71 -57.96, -38.02 APE12-dist-na 17.0837 APE11-dist-na 13.8991 APE10-dist-na 11.4361 APE9-dist-in 7.9103 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 1.85 0.177 0.207 B 327.0 276.0 0 30 30 0 [[589, 926]] 1.0 8s16 Homo sapiens TYR_KIT_HUMAN TYR 2.3e-104 354.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit

PDB: 8S16 — TYR KIT_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name