PDB: 8R7G — TKL ACVR1_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 8R7GB
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 8R7GA Q04771 205 499 509.0 YEE:501 Type1 Inactive DFGin 7.873 13.114 BLAminus -125.34, 176.57 61.75, 79.56 -92.18, 25.14 304.23, 156.54 -66.96, -22.65 in-out in 8.25 Saltbr-out 4.604 HRD-in -86.83, -53.56 76.37, 0.62 out-in-out SNCoio in-out ActLoopNT-in 3.003 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -99.53, 168.92 APE9-dihe-na -60.18, 166.2 APE8-dihe-in -61.99, 126.25 APE8-rot-in 300.64 APE67-dihe-in -53.95, -28.13 -65.83, -38.49 APE12-dist-in 10.96 APE11-dist-out 7.324 APE10-dist-out 9.123 APE9-dist-in 3.874 Q207D None None XRAY 2.09 0.228 0.253 A 301 293 2 0 0 0 [[207, 497]] 1.0 8r7g TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2 267 266 353 354 355 357 359 235 248 252 333 335 334 336 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 8R7GB Q04771 205 498 509.0 YEE:501 Type1 Inactive DFGin 7.702 12.84 BLAminus -132.3, 173.86 64.56, 82.91 -96.15, 22.56 312.11, 149.54 -62.02, -22.37 in-out in 8.118 Saltbr-out 3.902 HRD-in -80.65, -58.3 79.92, 2.55 out-in-out SNCoio in-out ActLoopNT-in 2.903 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -108.9, 170.94 APE9-dihe-na -68.07, 167.85 APE8-dihe-in -62.36, 121.37 APE8-rot-in 303.04 APE67-dihe-in -62.81, -26.45 -65.67, -29.35 APE12-dist-in 10.843 APE11-dist-out 7.472 APE10-dist-out 9.043 APE9-dist-in 4.083 Q207D None None XRAY 2.09 0.228 0.253 B 301 293 1 0 0 0 [[207, 497]] 1.0 8r7g TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2 267 266 353 354 355 357 359 235 248 252 333 335 334 336 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 8R7GC Q04771 206 498 509.0 YEE:501 Type1 None DFGin 7.86 12.623 BLAminus -132.3, 171.44 65.89, 83.48 -96.38, 20.1 305.34, 173.35 -63.32, -22.24 in-in in 8.155 Saltbr-in 3.027 HRD-in -79.84, -56.85 80.44, 0.82 in-in-none SNCiin in-none ActLoopNT-in 2.792 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_nnii APE10-dihe-na 999.0, -50.52 APE9-dihe-na -69.1, 173.0 APE8-dihe-in -60.22, 124.79 APE8-rot-in 310.22 APE67-dihe-in -65.34, -27.73 -64.05, -29.41 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-in 7.082 APE9-dist-in 3.578 Q207D None None XRAY 2.09 0.228 0.253 C 301 280 13 0 0 12 [[207, 497]] 1.0 8r7g TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2 267 266 353 354 355 357 359 235 248 252 333 335 334 336 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 8R7GD Q04771 204 498 509.0 YEE:501 Type1 Inactive DFGin 7.656 12.786 BLAminus -130.9, 171.35 64.69, 82.55 -97.53, 20.28 313.61, 165.44 -62.7, -21.28 in-none in 8.092 Saltbr-none 999.0 HRD-in -80.62, -57.63 79.17, 3.62 none-in-out SNCnio in-out ActLoopNT-in 2.934 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -131.29, 164.75 APE9-dihe-na -65.63, 171.5 APE8-dihe-in -60.25, 124.44 APE8-rot-in 310.83 APE67-dihe-in -65.19, -26.25 -64.07, -29.53 APE12-dist-in 10.404 APE11-dist-out 7.022 APE10-dist-out 8.812 APE9-dist-in 3.875 Q207D None None XRAY 2.09 0.228 0.253 D 301 291 4 0 0 4 [[207, 497]] 1.0 8r7g TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2 267 266 353 354 355 357 359 235 248 252 333 335 334 336 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 8R7G — TKL ACVR1_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 8R7GB
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 8R7GA Q04771 205 499 509.0 YEE:501 Type1 Inactive DFGin 7.873 13.114 BLAminus -125.34, 176.57 61.75, 79.56 -92.18, 25.14 304.23, 156.54 -66.96, -22.65 in-out in 8.25 Saltbr-out 4.604 HRD-in -86.83, -53.56 76.37, 0.62 out-in-out SNCoio in-out ActLoopNT-in 3.003 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -99.53, 168.92 APE9-dihe-na -60.18, 166.2 APE8-dihe-in -61.99, 126.25 APE8-rot-in 300.64 APE67-dihe-in -53.95, -28.13 -65.83, -38.49 APE12-dist-in 10.96 APE11-dist-out 7.324 APE10-dist-out 9.123 APE9-dist-in 3.874 Q207D None None XRAY 2.09 0.228 0.253 A 301 293 2 0 0 0 [[207, 497]] 1.0 8r7g Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2 267 266 353 354 355 357 359 235 248 252 333 335 334 336 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 8R7GB Q04771 205 498 509.0 YEE:501 Type1 Inactive DFGin 7.702 12.84 BLAminus -132.3, 173.86 64.56, 82.91 -96.15, 22.56 312.11, 149.54 -62.02, -22.37 in-out in 8.118 Saltbr-out 3.902 HRD-in -80.65, -58.3 79.92, 2.55 out-in-out SNCoio in-out ActLoopNT-in 2.903 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -108.9, 170.94 APE9-dihe-na -68.07, 167.85 APE8-dihe-in -62.36, 121.37 APE8-rot-in 303.04 APE67-dihe-in -62.81, -26.45 -65.67, -29.35 APE12-dist-in 10.843 APE11-dist-out 7.472 APE10-dist-out 9.043 APE9-dist-in 4.083 Q207D None None XRAY 2.09 0.228 0.253 B 301 293 1 0 0 0 [[207, 497]] 1.0 8r7g Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2 267 266 353 354 355 357 359 235 248 252 333 335 334 336 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 8R7GC Q04771 206 498 509.0 YEE:501 Type1 None DFGin 7.86 12.623 BLAminus -132.3, 171.44 65.89, 83.48 -96.38, 20.1 305.34, 173.35 -63.32, -22.24 in-in in 8.155 Saltbr-in 3.027 HRD-in -79.84, -56.85 80.44, 0.82 in-in-none SNCiin in-none ActLoopNT-in 2.792 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_nnii APE10-dihe-na 999.0, -50.52 APE9-dihe-na -69.1, 173.0 APE8-dihe-in -60.22, 124.79 APE8-rot-in 310.22 APE67-dihe-in -65.34, -27.73 -64.05, -29.41 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-in 7.082 APE9-dist-in 3.578 Q207D None None XRAY 2.09 0.228 0.253 C 301 280 13 0 0 12 [[207, 497]] 1.0 8r7g Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2 267 266 353 354 355 357 359 235 248 252 333 335 334 336 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 8R7GD Q04771 204 498 509.0 YEE:501 Type1 Inactive DFGin 7.656 12.786 BLAminus -130.9, 171.35 64.69, 82.55 -97.53, 20.28 313.61, 165.44 -62.7, -21.28 in-none in 8.092 Saltbr-none 999.0 HRD-in -80.62, -57.63 79.17, 3.62 none-in-out SNCnio in-out ActLoopNT-in 2.934 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -131.29, 164.75 APE9-dihe-na -65.63, 171.5 APE8-dihe-in -60.25, 124.44 APE8-rot-in 310.83 APE67-dihe-in -65.19, -26.25 -64.07, -29.53 APE12-dist-in 10.404 APE11-dist-out 7.022 APE10-dist-out 8.812 APE9-dist-in 3.875 Q207D None None XRAY 2.09 0.228 0.253 D 301 291 4 0 0 4 [[207, 497]] 1.0 8r7g Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2 267 266 353 354 355 357 359 235 248 252 333 335 334 336 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 8R7G — TKL ACVR1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name