| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | FGFR4 | FGFR4_HUMAN | 8KH7A | P22455 | 454 | 751 | 802.0 | VVW:802 | Type1 | Inactive | DFGin | 5.2756 | 12.7215 | BLAplus | -115.76, 162.05 | 57.7, 35.04 | -83.79, -12.86 | 51.09, 87.09 | -105.89, 24.32 | in-in | in | 7.4168 | Saltbr-in | 2.7818 | HRD-in | -69.92, -54.01 | 83.03, -10.74 | in-out-out | SNCioo | out-out | ActLoopNT-out | 8.5138 | ActLoopCT-out | TYR | APEdihe_iioai | APEdist_aaao | APE10-dihe-in | -75.04, 139.88 | APE9-dihe-in | -109.97, 90.79 | APE8-dihe-out | -58.47, -20.09 | APE8-rot-na | 333.49 | APE67-dihe-in | -69.7, -7.45 | -60.7, -23.51 | APE12-dist-na | 19.7984 | APE11-dist-na | 21.4206 | APE10-dist-na | 17.2658 | APE9-dist-out | 11.9913 | R664E | None | None | XRAY | 1.52 | 0.166 | 0.195 | A | 311.0 | 290.0 | 8 | 30 | 30 | 0 | [[467, 745]] | 1.0 | 8kh7 | TYR_FGFR4_HUMAN | TYR | 1.9e-100 | 341.4 | 1.0 | 261.0 | 261.0 | 629 | 630 | 631 | 633 | 635 | 503 | 520 | 524 | 609 | 611 | 610 | 612.0 | 671 | 659 | 654 | 653 | 652 | 651 | 650 | 649 | 648 | 551 | Fibroblast growth factor receptor 4 |
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | FGFR4 | FGFR4_HUMAN | 8KH7A | P22455 | 454 | 751 | 802.0 | VVW:802 | Type1 | Inactive | DFGin | 5.2756 | 12.7215 | BLAplus | -115.76, 162.05 | 57.7, 35.04 | -83.79, -12.86 | 51.09, 87.09 | -105.89, 24.32 | in-in | in | 7.4168 | Saltbr-in | 2.7818 | HRD-in | -69.92, -54.01 | 83.03, -10.74 | in-out-out | SNCioo | out-out | ActLoopNT-out | 8.5138 | ActLoopCT-out | TYR | APEdihe_iioai | APEdist_aaao | APE10-dihe-in | -75.04, 139.88 | APE9-dihe-in | -109.97, 90.79 | APE8-dihe-out | -58.47, -20.09 | APE8-rot-na | 333.49 | APE67-dihe-in | -69.7, -7.45 | -60.7, -23.51 | APE12-dist-na | 19.7984 | APE11-dist-na | 21.4206 | APE10-dist-na | 17.2658 | APE9-dist-out | 11.9913 | R664E | None | None | XRAY | 1.52 | 0.166 | 0.195 | A | 311.0 | 290.0 | 8 | 30 | 30 | 0 | [[467, 745]] | 1.0 | 8kh7 | Homo sapiens | TYR_FGFR4_HUMAN | TYR | 1.9e-100 | 341.4 | 1.0 | 261.0 | 261.0 | 629 | 630 | 631 | 633 | 635 | 503 | 520 | 524 | 609 | 611 | 610 | 612.0 | 671 | 659 | 654 | 653 | 652 | 651 | 650 | 649 | 648 | 551 | Fibroblast growth factor receptor 4 |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|