PDB: 8H7X — TYR EGFR_HUMAN

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 8H7XA
DFGinter None 1 50.0% 8H7XB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 8H7XA P00533 697 1019 1210.0 6GY:1500 Type1 Active DFGin 5.6354 13.7718 BLAminus -162.89, 168.84 77.21, 81.71 -97.92, 23.57 309.06, 76.3 -58.42, -31.29 in-in in 8.8993 Saltbr-in 3.1627 HRD-in -78.19, -35.41 64.93, 5.25 in-in-in SNCiii in-in ActLoopNT-in 3.0319 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -124.33, 109.95 APE9-dihe-in -128.71, 142.43 APE8-dihe-in -73.85, 112.86 APE8-rot-na 33.56 APE67-dihe-in -80.76, -11.68 -63.25, -24.22 APE12-dist-na 12.2914 APE11-dist-na 9.1117 APE10-dist-na 10.2887 APE9-dist-in 6.2687 T790M,C797S None None XRAY 3.404 0.189 0.256 A 330.0 299.0 0 30 30 0 [[712, 970]] 1.0 8h7x TYR_EGFR_HUMAN TYR 6.2e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8H7XB P00533 697 1018 1210.0 No_ligand No_ligand Inactive DFGinter 8.4737 4.5393 None -64.56, 138.69 -118.16, 46.75 -84.7, 147.88 264.74, 132.9 65.94, 48.18 in-in in 7.861 Saltbr-in 2.7426 HRD-in -95.26, -40.89 71.41, -6.98 in-out-none SNCion out-none ActLoopNT-out 5.2837 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 134.76 APE8-dihe-in -79.73, 83.74 APE8-rot-na 34.28 APE67-dihe-in -52.0, -45.23 -70.34, -44.7 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.766 T790M,C797S None None XRAY 3.404 0.189 0.256 B 330.0 304.0 7 30 23 7 [[712, 970]] 1.0 8h7x TYR_EGFR_HUMAN TYR 6.2e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 8H7X — TYR EGFR_HUMAN

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 8H7XA
DFGinter None 1 50.0% 8H7XB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 8H7XA P00533 697 1019 1210.0 6GY:1500 Type1 Active DFGin 5.6354 13.7718 BLAminus -162.89, 168.84 77.21, 81.71 -97.92, 23.57 309.06, 76.3 -58.42, -31.29 in-in in 8.8993 Saltbr-in 3.1627 HRD-in -78.19, -35.41 64.93, 5.25 in-in-in SNCiii in-in ActLoopNT-in 3.0319 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -124.33, 109.95 APE9-dihe-in -128.71, 142.43 APE8-dihe-in -73.85, 112.86 APE8-rot-na 33.56 APE67-dihe-in -80.76, -11.68 -63.25, -24.22 APE12-dist-na 12.2914 APE11-dist-na 9.1117 APE10-dist-na 10.2887 APE9-dist-in 6.2687 T790M,C797S None None XRAY 3.404 0.189 0.256 A 330.0 299.0 0 30 30 0 [[712, 970]] 1.0 8h7x Homo sapiens TYR_EGFR_HUMAN TYR 6.2e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8H7XB P00533 697 1018 1210.0 No_ligand No_ligand Inactive DFGinter 8.4737 4.5393 None -64.56, 138.69 -118.16, 46.75 -84.7, 147.88 264.74, 132.9 65.94, 48.18 in-in in 7.861 Saltbr-in 2.7426 HRD-in -95.26, -40.89 71.41, -6.98 in-out-none SNCion out-none ActLoopNT-out 5.2837 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 134.76 APE8-dihe-in -79.73, 83.74 APE8-rot-na 34.28 APE67-dihe-in -52.0, -45.23 -70.34, -44.7 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.766 T790M,C797S None None XRAY 3.404 0.189 0.256 B 330.0 304.0 7 30 23 7 [[712, 970]] 1.0 8h7x Homo sapiens TYR_EGFR_HUMAN TYR 6.2e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 8H7X — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name