PDB: 8FV3 — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 50.0% 8FV3A
DFGin BLBtrans 2 50.0% 8FV3B
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 8FV3A P00533 701 1014 1210.0 ANP:1102 ATPlike Inactive DFGin 3.96 13.397 BLBplus -132.16, 169.96 65.72, 32.0 -78.17, 140.3 56.84, 82.43 67.0, 6.27 out-out out 13.544 Saltbr-out 14.732 HRD-in -69.71, -62.71 86.1, -12.85 out-out-none SNCoon out-none ActLoopNT-out 6.542 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 27.23 APE9-dihe-in -63.25, 122.03 APE8-dihe-in -75.98, 67.82 APE8-rot-na 29.66 APE67-dihe-in -76.37, -3.74 -56.38, -36.64 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 12.726 APE9-dist-in 7.987 T790M,V948R None None XRAY 2.1 0.191 0.226 A 328 299 14 0 0 12 [[712, 970]] 1.0 8fv3 TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8FV3C P00533 701 1009 1210.0 YA6:1101 Type1.5_Back Inactive DFGin 4.976 14.226 BLBplus -140.28, 173.45 62.97, 49.98 -100.77, 147.39 44.76, 100.07 103.45, -165.1 out-out out 13.733 Saltbr-out 12.977 HRD-in -73.54, -54.95 81.69, -9.29 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 112.62 APE8-dihe-in -78.9, 67.7 APE8-rot-na 28.92 APE67-dihe-in -74.17, -1.93 -55.66, -42.6 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.207 T790M,V948R None None XRAY 2.1 0.191 0.226 C 328 291 18 0 0 17 [[712, 970]] 1.0 8fv3 TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8FV3B P00533 701 1021 1210.0 ANP:1102 ATPlike Inactive DFGin 5.439 16.496 BLBtrans -118.64, 177.37 63.4, 20.55 -58.75, 145.81 159.38, 77.34 77.7, -11.94 out-out out 13.907 Saltbr-out 12.609 HRD-in -79.27, -57.12 85.07, -16.18 out-out-none SNCoon out-none ActLoopNT-out 6.551 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, -85.47 APE9-dihe-in -94.5, 111.51 APE8-dihe-in -78.45, 79.51 APE8-rot-na 26.67 APE67-dihe-in -72.96, -7.53 -57.83, -45.1 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 12.158 APE9-dist-in 7.609 T790M,V948R None None XRAY 2.1 0.191 0.226 B 328 307 12 0 0 12 [[712, 970]] 1.0 8fv3 TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8FV3D P00533 701 1008 1210.0 ANP:1102 ATPlike Inactive DFGin 5.123 16.069 BLBtrans -118.91, 178.66 63.22, 20.1 -58.76, 136.59 151.59, 72.8 86.53, -14.56 out-out out 13.636 Saltbr-out 11.878 HRD-in -77.73, -54.76 83.51, -15.49 out-out-none SNCoon out-none ActLoopNT-out 6.686 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, -35.35 APE9-dihe-in -75.26, 139.37 APE8-dihe-in -77.41, 75.08 APE8-rot-na 30.35 APE67-dihe-in -77.52, -1.37 -56.44, -41.73 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 12.989 APE9-dist-in 7.856 T790M,V948R None None XRAY 2.1 0.191 0.226 D 328 295 13 0 0 12 [[712, 970]] 1.0 8fv3 TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 8FV3 — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 50.0% 8FV3A
DFGin BLBtrans 2 50.0% 8FV3B
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 8FV3A P00533 701 1014 1210.0 ANP:1102 ATPlike Inactive DFGin 3.96 13.397 BLBplus -132.16, 169.96 65.72, 32.0 -78.17, 140.3 56.84, 82.43 67.0, 6.27 out-out out 13.544 Saltbr-out 14.732 HRD-in -69.71, -62.71 86.1, -12.85 out-out-none SNCoon out-none ActLoopNT-out 6.542 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 27.23 APE9-dihe-in -63.25, 122.03 APE8-dihe-in -75.98, 67.82 APE8-rot-na 29.66 APE67-dihe-in -76.37, -3.74 -56.38, -36.64 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 12.726 APE9-dist-in 7.987 T790M,V948R None None XRAY 2.1 0.191 0.226 A 328 299 14 0 0 12 [[712, 970]] 1.0 8fv3 Homo sapiens TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8FV3C P00533 701 1009 1210.0 YA6:1101 Type1.5_Back Inactive DFGin 4.976 14.226 BLBplus -140.28, 173.45 62.97, 49.98 -100.77, 147.39 44.76, 100.07 103.45, -165.1 out-out out 13.733 Saltbr-out 12.977 HRD-in -73.54, -54.95 81.69, -9.29 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 112.62 APE8-dihe-in -78.9, 67.7 APE8-rot-na 28.92 APE67-dihe-in -74.17, -1.93 -55.66, -42.6 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.207 T790M,V948R None None XRAY 2.1 0.191 0.226 C 328 291 18 0 0 17 [[712, 970]] 1.0 8fv3 Homo sapiens TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8FV3B P00533 701 1021 1210.0 ANP:1102 ATPlike Inactive DFGin 5.439 16.496 BLBtrans -118.64, 177.37 63.4, 20.55 -58.75, 145.81 159.38, 77.34 77.7, -11.94 out-out out 13.907 Saltbr-out 12.609 HRD-in -79.27, -57.12 85.07, -16.18 out-out-none SNCoon out-none ActLoopNT-out 6.551 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, -85.47 APE9-dihe-in -94.5, 111.51 APE8-dihe-in -78.45, 79.51 APE8-rot-na 26.67 APE67-dihe-in -72.96, -7.53 -57.83, -45.1 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 12.158 APE9-dist-in 7.609 T790M,V948R None None XRAY 2.1 0.191 0.226 B 328 307 12 0 0 12 [[712, 970]] 1.0 8fv3 Homo sapiens TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8FV3D P00533 701 1008 1210.0 ANP:1102 ATPlike Inactive DFGin 5.123 16.069 BLBtrans -118.91, 178.66 63.22, 20.1 -58.76, 136.59 151.59, 72.8 86.53, -14.56 out-out out 13.636 Saltbr-out 11.878 HRD-in -77.73, -54.76 83.51, -15.49 out-out-none SNCoon out-none ActLoopNT-out 6.686 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, -35.35 APE9-dihe-in -75.26, 139.37 APE8-dihe-in -77.41, 75.08 APE8-rot-na 30.35 APE67-dihe-in -77.52, -1.37 -56.44, -41.73 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 12.989 APE9-dist-in 7.856 T790M,V948R None None XRAY 2.1 0.191 0.226 D 328 295 13 0 0 12 [[712, 970]] 1.0 8fv3 Homo sapiens TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 8FV3 — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name