PDB: 8BUB — CMGC CDK12_HUMAN

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 8BUBB
DFGin None 1 33.3% 8BUBH
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC CDK12 CDK12_HUMAN 8BUBB 3.42 Inactive DFGin‑BLAminus in-in out-out nonTYR APEdihe_aaoii APEdist_iioo RNU Type1 715 - 1041 0 TPO893 K965R Cyclin-dependent kinase 12
CMGC CDK12 CDK12_HUMAN 8BUBE 3.42 Inactive DFGin‑BLAminus in-in out-out nonTYR APEdihe_aaoii APEdist_iooo RNU Type1 715 - 1043 0 TPO893 K965R Cyclin-dependent kinase 12
CMGC CDK12 CDK12_HUMAN 8BUBH 3.42 Inactive DFGin‑None in-in out-out nonTYR APEdihe_aaooo APEdist_iiii RNU Type1 715 - 1044 0 TPO893 K965R Cyclin-dependent kinase 12

PDB: 8BUB — CMGC CDK12_HUMAN

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 8BUBB
DFGin None 1 33.3% 8BUBH
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC CDK12 CDK12_HUMAN 8BUBB 3.42 Inactive DFGin‑BLAminus in-in out-out nonTYR APEdihe_aaoii APEdist_iioo RNU Type1 715 - 1041 0 TPO893 K965R Cyclin-dependent kinase 12 Homo sapiens
CMGC CDK12 CDK12_HUMAN 8BUBE 3.42 Inactive DFGin‑BLAminus in-in out-out nonTYR APEdihe_aaoii APEdist_iooo RNU Type1 715 - 1043 0 TPO893 K965R Cyclin-dependent kinase 12 Homo sapiens
CMGC CDK12 CDK12_HUMAN 8BUBH 3.42 Inactive DFGin‑None in-in out-out nonTYR APEdihe_aaooo APEdist_iiii RNU Type1 715 - 1044 0 TPO893 K965R Cyclin-dependent kinase 12 Homo sapiens

PDB: 8BUB — CMGC CDK12_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism