| Family | Gene | UniprotID | PDB | Resolution | Activity | Spatial-Dihedral | Chelix-SaltBridge | ActLoopNT-ActLoopCT | APEtype | APEdihe | APEdist | Ligand | Ligand Type | Residues in structure | Unresolved residues in A-loop | Phosphorylation | Mutation | Protein |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TKL | IRAK4 | IRAK4_HUMAN | 8BR6AAA | 2.167 | Inactive | DFGin‑BLAminus | in-out | in-in | nonTYR | APEdihe_aaiii | APEdist_iiii | R6I | Type1 | 165 - 459 | 0 | TPO345,SEP346 | K400A,E401A,E402A | Interleukin-1 receptor-associated kinase 4 |
| TKL | IRAK4 | IRAK4_HUMAN | 8BR6BBB | 2.167 | Inactive | DFGin‑BLAminus | in-out | in-in | nonTYR | APEdihe_aaiii | APEdist_iiii | R6I | Type1 | 165 - 459 | 0 | TPO345,SEP346 | K400A,E401A,E402A | Interleukin-1 receptor-associated kinase 4 |
| Family | Gene | UniprotID | PDB | Resolution | Activity | Spatial-Dihedral | Chelix-SaltBridge | ActLoopNT-ActLoopCT | APEtype | APEdihe | APEdist | Ligand | Ligand Type | Residues in structure | Unresolved residues in A-loop | Phosphorylation | Mutation | Protein | Organism |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TKL | IRAK4 | IRAK4_HUMAN | 8BR6AAA | 2.167 | Inactive | DFGin‑BLAminus | in-out | in-in | nonTYR | APEdihe_aaiii | APEdist_iiii | R6I | Type1 | 165 - 459 | 0 | TPO345,SEP346 | K400A,E401A,E402A | Interleukin-1 receptor-associated kinase 4 | Homo sapiens |
| TKL | IRAK4 | IRAK4_HUMAN | 8BR6BBB | 2.167 | Inactive | DFGin‑BLAminus | in-out | in-in | nonTYR | APEdihe_aaiii | APEdist_iiii | R6I | Type1 | 165 - 459 | 0 | TPO345,SEP346 | K400A,E401A,E402A | Interleukin-1 receptor-associated kinase 4 | Homo sapiens |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
| Family | Gene | UniprotID | PDB | Resolution | Activity | Spatial-Dihedral | Chelix-SaltBridge | ActLoopNT-ActLoopCT | APEtype | APEdihe | APEdist | Ligand | Ligand Type | Residues in structure | Unresolved residues in A-loop | Phosphorylation | Mutation | Protein | Organism |
|---|