| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | MET | MET_HUMAN | 8AU3A | P08581 | 1052 | 1349 | 1390.0 | 3E8:1401 | Type1 | Inactive | DFGin | 5.6836 | 14.2897 | BLBplus | -124.89, -160.9 | 56.91, 51.79 | -144.24, 164.35 | 65.96, 84.2 | 62.67, -127.3 | out-out | out | 12.1068 | Saltbr-out | 10.7283 | HRD-in | -74.56, -50.99 | 74.86, 1.96 | out-out-out | SNCooo | out-out | ActLoopNT-out | 10.7586 | ActLoopCT-out | TYR | APEdihe_nnoai | APEdist_aaao | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, -67.06 | APE8-dihe-out | -64.75, -14.77 | APE8-rot-na | 35.69 | APE67-dihe-in | -73.18, -9.04 | -40.0, -46.69 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-out | 10.2708 | Y1234E,Y1235E | None | None | XRAY | 2.26 | 0.198 | 0.24 | A | 299.0 | 285.0 | 13 | 32 | 19 | 13 | [[1078, 1339]] | 1.0 | 8au3 | TYR_MET_HUMAN | TYR | 4.5e-91 | 310.8 | 2.0 | 260.0 | 259.0 | 1221 | 1222 | 1223 | 1225 | 1227 | 1110 | 1127 | 1131 | 1201 | 1203 | 1202 | 1204.0 | 1265 | 1253 | 1248 | 1247 | 1246 | 1245 | 1244 | 1243 | 1242 | 1158 | Hepatocyte growth factor receptor |
| TYR | MET | MET_HUMAN | 8AU3B | P08581 | 1056 | 1349 | 1390.0 | 3E8:1401 | Type1 | Inactive | DFGin | 5.4962 | 14.4728 | BLBplus | -125.67, -163.77 | 56.96, 51.67 | -147.0, 169.32 | 67.61, 95.69 | 59.55, -126.73 | out-out | out | 15.3906 | Saltbr-out | 16.7854 | HRD-in | -71.6, -51.19 | 76.55, 0.05 | out-out-out | SNCooo | out-out | ActLoopNT-out | 10.966 | ActLoopCT-out | TYR | APEdihe_nnoai | APEdist_aaao | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, -66.77 | APE8-dihe-out | -65.4, -13.15 | APE8-rot-na | 35.16 | APE67-dihe-in | -76.94, -3.51 | -35.23, -49.22 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-out | 10.3309 | Y1234E,Y1235E | None | None | XRAY | 2.26 | 0.198 | 0.24 | B | 299.0 | 281.0 | 13 | 32 | 19 | 13 | [[1078, 1339]] | 1.0 | 8au3 | TYR_MET_HUMAN | TYR | 4.5e-91 | 310.8 | 2.0 | 260.0 | 259.0 | 1221 | 1222 | 1223 | 1225 | 1227 | 1110 | 1127 | 1131 | 1201 | 1203 | 1202 | 1204.0 | 1265 | 1253 | 1248 | 1247 | 1246 | 1245 | 1244 | 1243 | 1242 | 1158 | Hepatocyte growth factor receptor |
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | MET | MET_HUMAN | 8AU3A | P08581 | 1052 | 1349 | 1390.0 | 3E8:1401 | Type1 | Inactive | DFGin | 5.6836 | 14.2897 | BLBplus | -124.89, -160.9 | 56.91, 51.79 | -144.24, 164.35 | 65.96, 84.2 | 62.67, -127.3 | out-out | out | 12.1068 | Saltbr-out | 10.7283 | HRD-in | -74.56, -50.99 | 74.86, 1.96 | out-out-out | SNCooo | out-out | ActLoopNT-out | 10.7586 | ActLoopCT-out | TYR | APEdihe_nnoai | APEdist_aaao | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, -67.06 | APE8-dihe-out | -64.75, -14.77 | APE8-rot-na | 35.69 | APE67-dihe-in | -73.18, -9.04 | -40.0, -46.69 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-out | 10.2708 | Y1234E,Y1235E | None | None | XRAY | 2.26 | 0.198 | 0.24 | A | 299.0 | 285.0 | 13 | 32 | 19 | 13 | [[1078, 1339]] | 1.0 | 8au3 | Homo sapiens | TYR_MET_HUMAN | TYR | 4.5e-91 | 310.8 | 2.0 | 260.0 | 259.0 | 1221 | 1222 | 1223 | 1225 | 1227 | 1110 | 1127 | 1131 | 1201 | 1203 | 1202 | 1204.0 | 1265 | 1253 | 1248 | 1247 | 1246 | 1245 | 1244 | 1243 | 1242 | 1158 | Hepatocyte growth factor receptor |
| TYR | MET | MET_HUMAN | 8AU3B | P08581 | 1056 | 1349 | 1390.0 | 3E8:1401 | Type1 | Inactive | DFGin | 5.4962 | 14.4728 | BLBplus | -125.67, -163.77 | 56.96, 51.67 | -147.0, 169.32 | 67.61, 95.69 | 59.55, -126.73 | out-out | out | 15.3906 | Saltbr-out | 16.7854 | HRD-in | -71.6, -51.19 | 76.55, 0.05 | out-out-out | SNCooo | out-out | ActLoopNT-out | 10.966 | ActLoopCT-out | TYR | APEdihe_nnoai | APEdist_aaao | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, -66.77 | APE8-dihe-out | -65.4, -13.15 | APE8-rot-na | 35.16 | APE67-dihe-in | -76.94, -3.51 | -35.23, -49.22 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-out | 10.3309 | Y1234E,Y1235E | None | None | XRAY | 2.26 | 0.198 | 0.24 | B | 299.0 | 281.0 | 13 | 32 | 19 | 13 | [[1078, 1339]] | 1.0 | 8au3 | Homo sapiens | TYR_MET_HUMAN | TYR | 4.5e-91 | 310.8 | 2.0 | 260.0 | 259.0 | 1221 | 1222 | 1223 | 1225 | 1227 | 1110 | 1127 | 1131 | 1201 | 1203 | 1202 | 1204.0 | 1265 | 1253 | 1248 | 1247 | 1246 | 1245 | 1244 | 1243 | 1242 | 1158 | Hepatocyte growth factor receptor |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|