Hover over column headers for tooltip help
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | JAK2-2 | JAK2_HUMAN | 7RN6A | O60674 | 839 | 1130 | 1132.0 | 046:61201 | Type2 | Inactive | DFGout | 14.849 | 10.032 | BBAminus | -142.9, -161.3 | -155.9, 101.54 | -56.95, -47.21 | 271.11, 99.06 | 62.67, 34.57 | in-in | in | 8.4 | Saltbr-in | 2.853 | HRD-in | -71.23, -54.0 | 79.2, -32.78 | in-none-out | SNCino | none-out | ActLoopNT-none | 999.0 | ActLoopCT-out | TYR | APEdihe_nioai | APEdist_aaao | APE10-dihe-none | 999.0, 23.78 | APE9-dihe-in | -68.64, 133.62 | APE8-dihe-out | -69.28, -14.0 | APE8-rot-na | 30.51 | APE67-dihe-in | -77.29, 3.35 | -60.18, -24.91 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 11.997 | APE9-dist-out | 11.023 | None | PTR1007 | PTR1007 | XRAY | 1.5 | 0.19 | 0.214 | A | 298 | 270 | 22 | 0 | 0 | 16 | [[545, 807], [849, 1125]] | 2.0 | 7rn6 | TYR_JAK2-2_HUMAN | TYR | 2.6e-87 | 298.4 | 1 | 260 | 260 | 993 | 994 | 995 | 997 | 999 | 882 | 898 | 902 | 973 | 975 | 974 | 976 | 1036 | 1024 | 1019 | 1018 | 1017 | 1016 | 1015 | 1014 | 1013 | 930 | Tyrosine-protein kinase JAK2 |
Hover over column headers for tooltip help
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | JAK2-2 | JAK2_HUMAN | 7RN6A | O60674 | 839 | 1130 | 1132.0 | 046:61201 | Type2 | Inactive | DFGout | 14.849 | 10.032 | BBAminus | -142.9, -161.3 | -155.9, 101.54 | -56.95, -47.21 | 271.11, 99.06 | 62.67, 34.57 | in-in | in | 8.4 | Saltbr-in | 2.853 | HRD-in | -71.23, -54.0 | 79.2, -32.78 | in-none-out | SNCino | none-out | ActLoopNT-none | 999.0 | ActLoopCT-out | TYR | APEdihe_nioai | APEdist_aaao | APE10-dihe-none | 999.0, 23.78 | APE9-dihe-in | -68.64, 133.62 | APE8-dihe-out | -69.28, -14.0 | APE8-rot-na | 30.51 | APE67-dihe-in | -77.29, 3.35 | -60.18, -24.91 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 11.997 | APE9-dist-out | 11.023 | None | PTR1007 | PTR1007 | XRAY | 1.5 | 0.19 | 0.214 | A | 298 | 270 | 22 | 0 | 0 | 16 | [[545, 807], [849, 1125]] | 2.0 | 7rn6 | Homo sapiens | TYR_JAK2-2_HUMAN | TYR | 2.6e-87 | 298.4 | 1 | 260 | 260 | 993 | 994 | 995 | 997 | 999 | 882 | 898 | 902 | 973 | 975 | 974 | 976 | 1036 | 1024 | 1019 | 1018 | 1017 | 1016 | 1015 | 1014 | 1013 | 930 | Tyrosine-protein kinase JAK2 |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
Hover over column headers for tooltip help
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|