PDB: 7QG5 — TKL IRAK4_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 7QG5B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 7QG5A Q9NWZ3 165 458 460.0 B7R:501 Type1 Inactive DFGin 6.578 14.4932 BLAminus -124.15, 174.43 61.08, 84.14 -101.81, 21.99 311.05, 99.37 -64.51, -29.58 in-out in 8.8835 Saltbr-out 3.9488 HRD-in -68.99, -49.5 76.63, -2.55 out-in-in SNCoii in-in ActLoopNT-in 2.8887 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -120.94, 161.62 APE9-dihe-na 129.5, -173.09 APE8-dihe-in -108.69, 116.59 APE8-rot-in 312.95 APE67-dihe-in -65.31, -14.05 -47.57, -46.29 APE12-dist-in 9.9238 APE11-dist-in 11.7586 APE10-dist-in 6.4022 APE9-dist-in 3.9224 None TPO345,SEP346 TPO345,SEP346 XRAY 2.3 0.249 0.275 A 308.0 270.0 24 30 24 6 [[183, 456]] 1.0 7qg5 TKL_IRAK4_HUMAN TKL 4.4e-84 288.1 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 7QG5B Q9NWZ3 164 458 460.0 B7R:501 Type1 Inactive DFGin 7.0578 14.3827 BLAminus -131.21, 172.38 65.67, 86.88 -104.52, 23.37 306.02, 106.65 -68.49, -29.45 in-out in 8.8038 Saltbr-out 3.9184 HRD-in -70.17, -49.03 75.63, -1.79 out-in-in SNCoii in-in ActLoopNT-in 2.8968 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -121.87, 162.12 APE9-dihe-na 129.84, -172.51 APE8-dihe-in -109.04, 117.43 APE8-rot-in 313.01 APE67-dihe-in -64.34, -13.55 -51.38, -43.59 APE12-dist-in 10.0182 APE11-dist-in 11.6188 APE10-dist-in 6.3383 APE9-dist-in 3.9707 None TPO345,SEP346 TPO345,SEP346 XRAY 2.3 0.249 0.275 B 308.0 281.0 14 30 24 6 [[183, 456]] 1.0 7qg5 TKL_IRAK4_HUMAN TKL 4.4e-84 288.1 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

PDB: 7QG5 — TKL IRAK4_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 7QG5B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 7QG5A Q9NWZ3 165 458 460.0 B7R:501 Type1 Inactive DFGin 6.578 14.4932 BLAminus -124.15, 174.43 61.08, 84.14 -101.81, 21.99 311.05, 99.37 -64.51, -29.58 in-out in 8.8835 Saltbr-out 3.9488 HRD-in -68.99, -49.5 76.63, -2.55 out-in-in SNCoii in-in ActLoopNT-in 2.8887 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -120.94, 161.62 APE9-dihe-na 129.5, -173.09 APE8-dihe-in -108.69, 116.59 APE8-rot-in 312.95 APE67-dihe-in -65.31, -14.05 -47.57, -46.29 APE12-dist-in 9.9238 APE11-dist-in 11.7586 APE10-dist-in 6.4022 APE9-dist-in 3.9224 None TPO345,SEP346 TPO345,SEP346 XRAY 2.3 0.249 0.275 A 308.0 270.0 24 30 24 6 [[183, 456]] 1.0 7qg5 Homo sapiens TKL_IRAK4_HUMAN TKL 4.4e-84 288.1 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 7QG5B Q9NWZ3 164 458 460.0 B7R:501 Type1 Inactive DFGin 7.0578 14.3827 BLAminus -131.21, 172.38 65.67, 86.88 -104.52, 23.37 306.02, 106.65 -68.49, -29.45 in-out in 8.8038 Saltbr-out 3.9184 HRD-in -70.17, -49.03 75.63, -1.79 out-in-in SNCoii in-in ActLoopNT-in 2.8968 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -121.87, 162.12 APE9-dihe-na 129.84, -172.51 APE8-dihe-in -109.04, 117.43 APE8-rot-in 313.01 APE67-dihe-in -64.34, -13.55 -51.38, -43.59 APE12-dist-in 10.0182 APE11-dist-in 11.6188 APE10-dist-in 6.3383 APE9-dist-in 3.9707 None TPO345,SEP346 TPO345,SEP346 XRAY 2.3 0.249 0.275 B 308.0 281.0 14 30 24 6 [[183, 456]] 1.0 7qg5 Homo sapiens TKL_IRAK4_HUMAN TKL 4.4e-84 288.1 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

PDB: 7QG5 — TKL IRAK4_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name