PDB: 7K1H — TYR EGFR_HUMAN

Total number of chains: 6
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 6 100.0% 7K1HD
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 7K1HA P00533 701 1007 1210.0 VNS:1301,YY3:1302 Type3,Type1 Inactive DFGin 4.897 14.502 BLBplus -130.97, 170.62 58.17, 48.68 -100.05, 161.6 49.16, 78.42 69.2, 1.23 out-out out 13.749 Saltbr-out 11.264 HRD-in -77.07, -52.87 73.56, -9.67 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 120.57 APE8-dihe-in -79.59, 69.97 APE8-rot-na 32.69 APE67-dihe-in -73.02, -4.47 -58.4, -43.53 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.87 L858R,V948R None None XRAY 2.602 0.233 0.275 A 331 291 16 0 0 16 [[712, 970]] 1.0 7k1h TYR_EGFR_HUMAN TYR 8.5e-87 296.8 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7K1HB P00533 701 1008 1210.0 VNS:1301,YY3:1302 Type3,Type1 Inactive DFGin 5.245 14.539 BLBplus -131.19, 172.0 58.43, 45.25 -101.59, 170.23 51.81, 92.29 77.64, 116.53 out-out out 13.419 Saltbr-out 9.137 HRD-in -79.53, -53.07 76.7, -9.03 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 117.65 APE8-dihe-in -81.29, 70.54 APE8-rot-na 31.4 APE67-dihe-in -72.0, -4.51 -57.97, -43.84 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.952 L858R,V948R None None XRAY 2.602 0.233 0.275 B 331 291 17 0 0 17 [[712, 970]] 1.0 7k1h TYR_EGFR_HUMAN TYR 8.5e-87 296.8 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7K1HC P00533 701 1007 1210.0 VNS:1301,YY3:1302 Type3,Type1 Inactive DFGin 4.744 14.74 BLBplus -129.93, 170.49 56.69, 44.1 -96.18, 166.59 55.18, 77.55 73.78, 46.77 out-out out 13.454 Saltbr-out 8.834 HRD-in -79.27, -50.75 74.55, -8.77 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 118.24 APE8-dihe-in -82.15, 68.56 APE8-rot-na 31.93 APE67-dihe-in -74.95, -6.33 -58.99, -43.36 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.006 L858R,V948R None None XRAY 2.602 0.233 0.275 C 331 290 17 0 0 17 [[712, 970]] 1.0 7k1h TYR_EGFR_HUMAN TYR 8.5e-87 296.8 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7K1HD P00533 701 1007 1210.0 VNS:1301,YY3:1302 Type3,Type1 Inactive DFGin 5.019 14.819 BLBplus -131.91, 172.88 57.19, 43.91 -99.27, 163.9 51.77, 84.58 74.04, -2.08 out-out out 13.649 Saltbr-out 10.156 HRD-in -78.62, -53.76 74.56, -9.86 out-out-out SNCooo out-out ActLoopNT-out 9.68 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 117.98 APE8-dihe-in -78.93, 62.04 APE8-rot-na 29.95 APE67-dihe-in -73.79, -3.52 -56.56, -42.2 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.07 L858R,V948R None None XRAY 2.602 0.233 0.275 D 331 292 15 0 0 15 [[712, 970]] 1.0 7k1h TYR_EGFR_HUMAN TYR 8.5e-87 296.8 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7K1HE P00533 703 1007 1210.0 VNS:1301,YY3:1302 Type3,Type1 Inactive DFGin 5.157 14.635 BLBplus -131.84, 173.0 58.55, 47.55 -102.27, 167.87 51.85, 86.34 79.14, -85.43 out-out out 13.629 Saltbr-out 10.317 HRD-in -78.55, -50.1 74.47, -8.94 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 114.83 APE8-dihe-in -83.11, 68.71 APE8-rot-na 30.98 APE67-dihe-in -72.18, -4.84 -60.68, -43.88 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.99 L858R,V948R None None XRAY 2.602 0.233 0.275 E 331 289 16 0 0 16 [[712, 970]] 1.0 7k1h TYR_EGFR_HUMAN TYR 8.5e-87 296.8 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7K1HF P00533 701 1007 1210.0 VNS:1301,YY3:1302 Type3,Type1 Inactive DFGin 4.905 14.421 BLBplus -132.01, 174.64 57.0, 46.09 -100.49, 170.69 50.88, 85.85 82.59, -107.03 out-out out 13.717 Saltbr-out 10.964 HRD-in -78.66, -52.82 76.59, -9.2 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 119.26 APE8-dihe-in -81.53, 68.79 APE8-rot-na 32.04 APE67-dihe-in -72.57, -5.45 -59.56, -43.26 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.067 L858R,V948R None None XRAY 2.602 0.233 0.275 F 331 290 17 0 0 17 [[712, 970]] 1.0 7k1h TYR_EGFR_HUMAN TYR 8.5e-87 296.8 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 7K1H — TYR EGFR_HUMAN

Total number of chains: 6
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 6 100.0% 7K1HD
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 7K1HA P00533 701 1007 1210.0 VNS:1301,YY3:1302 Type3,Type1 Inactive DFGin 4.897 14.502 BLBplus -130.97, 170.62 58.17, 48.68 -100.05, 161.6 49.16, 78.42 69.2, 1.23 out-out out 13.749 Saltbr-out 11.264 HRD-in -77.07, -52.87 73.56, -9.67 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 120.57 APE8-dihe-in -79.59, 69.97 APE8-rot-na 32.69 APE67-dihe-in -73.02, -4.47 -58.4, -43.53 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.87 L858R,V948R None None XRAY 2.602 0.233 0.275 A 331 291 16 0 0 16 [[712, 970]] 1.0 7k1h Homo sapiens TYR_EGFR_HUMAN TYR 8.5e-87 296.8 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7K1HB P00533 701 1008 1210.0 VNS:1301,YY3:1302 Type3,Type1 Inactive DFGin 5.245 14.539 BLBplus -131.19, 172.0 58.43, 45.25 -101.59, 170.23 51.81, 92.29 77.64, 116.53 out-out out 13.419 Saltbr-out 9.137 HRD-in -79.53, -53.07 76.7, -9.03 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 117.65 APE8-dihe-in -81.29, 70.54 APE8-rot-na 31.4 APE67-dihe-in -72.0, -4.51 -57.97, -43.84 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.952 L858R,V948R None None XRAY 2.602 0.233 0.275 B 331 291 17 0 0 17 [[712, 970]] 1.0 7k1h Homo sapiens TYR_EGFR_HUMAN TYR 8.5e-87 296.8 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7K1HC P00533 701 1007 1210.0 VNS:1301,YY3:1302 Type3,Type1 Inactive DFGin 4.744 14.74 BLBplus -129.93, 170.49 56.69, 44.1 -96.18, 166.59 55.18, 77.55 73.78, 46.77 out-out out 13.454 Saltbr-out 8.834 HRD-in -79.27, -50.75 74.55, -8.77 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 118.24 APE8-dihe-in -82.15, 68.56 APE8-rot-na 31.93 APE67-dihe-in -74.95, -6.33 -58.99, -43.36 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.006 L858R,V948R None None XRAY 2.602 0.233 0.275 C 331 290 17 0 0 17 [[712, 970]] 1.0 7k1h Homo sapiens TYR_EGFR_HUMAN TYR 8.5e-87 296.8 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7K1HD P00533 701 1007 1210.0 VNS:1301,YY3:1302 Type3,Type1 Inactive DFGin 5.019 14.819 BLBplus -131.91, 172.88 57.19, 43.91 -99.27, 163.9 51.77, 84.58 74.04, -2.08 out-out out 13.649 Saltbr-out 10.156 HRD-in -78.62, -53.76 74.56, -9.86 out-out-out SNCooo out-out ActLoopNT-out 9.68 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 117.98 APE8-dihe-in -78.93, 62.04 APE8-rot-na 29.95 APE67-dihe-in -73.79, -3.52 -56.56, -42.2 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.07 L858R,V948R None None XRAY 2.602 0.233 0.275 D 331 292 15 0 0 15 [[712, 970]] 1.0 7k1h Homo sapiens TYR_EGFR_HUMAN TYR 8.5e-87 296.8 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7K1HE P00533 703 1007 1210.0 VNS:1301,YY3:1302 Type3,Type1 Inactive DFGin 5.157 14.635 BLBplus -131.84, 173.0 58.55, 47.55 -102.27, 167.87 51.85, 86.34 79.14, -85.43 out-out out 13.629 Saltbr-out 10.317 HRD-in -78.55, -50.1 74.47, -8.94 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 114.83 APE8-dihe-in -83.11, 68.71 APE8-rot-na 30.98 APE67-dihe-in -72.18, -4.84 -60.68, -43.88 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.99 L858R,V948R None None XRAY 2.602 0.233 0.275 E 331 289 16 0 0 16 [[712, 970]] 1.0 7k1h Homo sapiens TYR_EGFR_HUMAN TYR 8.5e-87 296.8 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7K1HF P00533 701 1007 1210.0 VNS:1301,YY3:1302 Type3,Type1 Inactive DFGin 4.905 14.421 BLBplus -132.01, 174.64 57.0, 46.09 -100.49, 170.69 50.88, 85.85 82.59, -107.03 out-out out 13.717 Saltbr-out 10.964 HRD-in -78.66, -52.82 76.59, -9.2 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 119.26 APE8-dihe-in -81.53, 68.79 APE8-rot-na 32.04 APE67-dihe-in -72.57, -5.45 -59.56, -43.26 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.067 L858R,V948R None None XRAY 2.602 0.233 0.275 F 331 290 17 0 0 17 [[712, 970]] 1.0 7k1h Homo sapiens TYR_EGFR_HUMAN TYR 8.5e-87 296.8 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 7K1H — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name