PDB: 7CGA — CMGC MK12_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 3 75.0% 7CGAB
DFGin BLAminus 1 25.0% 7CGAA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK12 MK12_HUMAN 7CGAB P53778 9 353 367.0 No_ligand No_ligand Inactive DFGin 6.2718 14.9689 ABAminus -110.86, -62.49 -102.64, 106.93 -94.38, 23.15 281.27, 88.51 -76.7, -25.42 in-in in 9.3125 Saltbr-in 2.6948 HRD-out -79.77, 114.92 -94.73, 10.19 in-in-out SNCiio in-out ActLoopNT-in 2.832 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiio APE10-dihe-na -57.15, 115.35 APE9-dihe-na -85.53, -51.12 APE8-dihe-in -51.2, 127.61 APE8-rot-in 312.11 APE67-dihe-in -63.98, -37.1 -91.4, -47.81 APE12-dist-out 6.5497 APE11-dist-in 9.4177 APE10-dist-in 7.485 APE9-dist-out 8.2712 None None None XRAY 3.15 0.163 0.218 B 348.0 345.0 0 25 25 0 [[27, 311]] 1.0 7cga CMGC_MAPK12_HUMAN CMGC 4.7e-85 291.4 1.0 301.0 301.0 170 171 172 174 176 56 74 78 150 152 151 153.0 208 195 190 189 188 187 186 185 184 110 Mitogen-activated protein kinase 12
CMGC MAPK12 MK12_HUMAN 7CGAC P53778 9 353 367.0 No_ligand No_ligand Inactive DFGin 6.7758 15.0681 ABAminus -115.28, -58.81 -110.37, 107.81 -95.19, 9.49 276.0, 86.92 -68.22, -14.79 in-in in 9.0832 Saltbr-in 3.2179 HRD-out -52.52, 150.85 -125.06, 11.69 in-in-out SNCiio in-out ActLoopNT-in 2.8531 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiio APE10-dihe-na -70.64, 118.03 APE9-dihe-na -84.55, -56.95 APE8-dihe-in -38.51, 120.41 APE8-rot-in 307.31 APE67-dihe-in -68.67, -38.99 -90.47, -46.68 APE12-dist-out 6.852 APE11-dist-in 9.3038 APE10-dist-in 7.744 APE9-dist-out 8.3788 None None None XRAY 3.15 0.163 0.218 C 348.0 345.0 0 25 25 0 [[27, 311]] 1.0 7cga CMGC_MAPK12_HUMAN CMGC 4.7e-85 291.4 1.0 301.0 301.0 170 171 172 174 176 56 74 78 150 152 151 153.0 208 195 190 189 188 187 186 185 184 110 Mitogen-activated protein kinase 12
CMGC MAPK12 MK12_HUMAN 7CGAD P53778 9 353 367.0 No_ligand No_ligand Inactive DFGin 6.6849 14.6524 ABAminus -119.58, -46.64 -112.32, 106.79 -92.17, 3.91 283.23, 103.54 -68.25, -11.35 in-in in 8.9869 Saltbr-in 2.679 HRD-out -90.17, 97.99 -84.21, 7.22 in-in-out SNCiio in-out ActLoopNT-in 2.9232 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiio APE10-dihe-na -63.92, 117.14 APE9-dihe-na -85.66, -57.65 APE8-dihe-in -38.77, 133.64 APE8-rot-in 316.55 APE67-dihe-in -82.55, -28.14 -108.44, -27.55 APE12-dist-out 6.9459 APE11-dist-in 9.4335 APE10-dist-in 7.7607 APE9-dist-out 8.5912 None None None XRAY 3.15 0.163 0.218 D 348.0 345.0 0 25 25 0 [[27, 311]] 1.0 7cga CMGC_MAPK12_HUMAN CMGC 4.7e-85 291.4 1.0 301.0 301.0 170 171 172 174 176 56 74 78 150 152 151 153.0 208 195 190 189 188 187 186 185 184 110 Mitogen-activated protein kinase 12
CMGC MAPK12 MK12_HUMAN 7CGAA P53778 9 353 367.0 No_ligand No_ligand Inactive DFGin 6.5112 14.8034 BLAminus -102.95, 174.14 60.25, 88.75 -98.15, 16.52 279.5, 81.2 -76.27, -1.53 in-in in 8.695 Saltbr-in 3.1003 HRD-in -69.44, -53.9 82.33, -6.84 in-in-out SNCiio in-out ActLoopNT-in 2.9193 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiio APE10-dihe-na -80.58, 119.04 APE9-dihe-na -87.45, -57.23 APE8-dihe-in -48.06, 132.7 APE8-rot-in 311.02 APE67-dihe-in -70.61, -33.55 -106.57, -39.76 APE12-dist-out 6.5319 APE11-dist-in 9.2949 APE10-dist-in 7.4909 APE9-dist-out 8.1688 None None None XRAY 3.15 0.163 0.218 A 348.0 345.0 0 25 25 0 [[27, 311]] 1.0 7cga CMGC_MAPK12_HUMAN CMGC 4.7e-85 291.4 1.0 301.0 301.0 170 171 172 174 176 56 74 78 150 152 151 153.0 208 195 190 189 188 187 186 185 184 110 Mitogen-activated protein kinase 12

PDB: 7CGA — CMGC MK12_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 3 75.0% 7CGAB
DFGin BLAminus 1 25.0% 7CGAA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK12 MK12_HUMAN 7CGAB P53778 9 353 367.0 No_ligand No_ligand Inactive DFGin 6.2718 14.9689 ABAminus -110.86, -62.49 -102.64, 106.93 -94.38, 23.15 281.27, 88.51 -76.7, -25.42 in-in in 9.3125 Saltbr-in 2.6948 HRD-out -79.77, 114.92 -94.73, 10.19 in-in-out SNCiio in-out ActLoopNT-in 2.832 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiio APE10-dihe-na -57.15, 115.35 APE9-dihe-na -85.53, -51.12 APE8-dihe-in -51.2, 127.61 APE8-rot-in 312.11 APE67-dihe-in -63.98, -37.1 -91.4, -47.81 APE12-dist-out 6.5497 APE11-dist-in 9.4177 APE10-dist-in 7.485 APE9-dist-out 8.2712 None None None XRAY 3.15 0.163 0.218 B 348.0 345.0 0 25 25 0 [[27, 311]] 1.0 7cga Homo sapiens CMGC_MAPK12_HUMAN CMGC 4.7e-85 291.4 1.0 301.0 301.0 170 171 172 174 176 56 74 78 150 152 151 153.0 208 195 190 189 188 187 186 185 184 110 Mitogen-activated protein kinase 12
CMGC MAPK12 MK12_HUMAN 7CGAC P53778 9 353 367.0 No_ligand No_ligand Inactive DFGin 6.7758 15.0681 ABAminus -115.28, -58.81 -110.37, 107.81 -95.19, 9.49 276.0, 86.92 -68.22, -14.79 in-in in 9.0832 Saltbr-in 3.2179 HRD-out -52.52, 150.85 -125.06, 11.69 in-in-out SNCiio in-out ActLoopNT-in 2.8531 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiio APE10-dihe-na -70.64, 118.03 APE9-dihe-na -84.55, -56.95 APE8-dihe-in -38.51, 120.41 APE8-rot-in 307.31 APE67-dihe-in -68.67, -38.99 -90.47, -46.68 APE12-dist-out 6.852 APE11-dist-in 9.3038 APE10-dist-in 7.744 APE9-dist-out 8.3788 None None None XRAY 3.15 0.163 0.218 C 348.0 345.0 0 25 25 0 [[27, 311]] 1.0 7cga Homo sapiens CMGC_MAPK12_HUMAN CMGC 4.7e-85 291.4 1.0 301.0 301.0 170 171 172 174 176 56 74 78 150 152 151 153.0 208 195 190 189 188 187 186 185 184 110 Mitogen-activated protein kinase 12
CMGC MAPK12 MK12_HUMAN 7CGAD P53778 9 353 367.0 No_ligand No_ligand Inactive DFGin 6.6849 14.6524 ABAminus -119.58, -46.64 -112.32, 106.79 -92.17, 3.91 283.23, 103.54 -68.25, -11.35 in-in in 8.9869 Saltbr-in 2.679 HRD-out -90.17, 97.99 -84.21, 7.22 in-in-out SNCiio in-out ActLoopNT-in 2.9232 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiio APE10-dihe-na -63.92, 117.14 APE9-dihe-na -85.66, -57.65 APE8-dihe-in -38.77, 133.64 APE8-rot-in 316.55 APE67-dihe-in -82.55, -28.14 -108.44, -27.55 APE12-dist-out 6.9459 APE11-dist-in 9.4335 APE10-dist-in 7.7607 APE9-dist-out 8.5912 None None None XRAY 3.15 0.163 0.218 D 348.0 345.0 0 25 25 0 [[27, 311]] 1.0 7cga Homo sapiens CMGC_MAPK12_HUMAN CMGC 4.7e-85 291.4 1.0 301.0 301.0 170 171 172 174 176 56 74 78 150 152 151 153.0 208 195 190 189 188 187 186 185 184 110 Mitogen-activated protein kinase 12
CMGC MAPK12 MK12_HUMAN 7CGAA P53778 9 353 367.0 No_ligand No_ligand Inactive DFGin 6.5112 14.8034 BLAminus -102.95, 174.14 60.25, 88.75 -98.15, 16.52 279.5, 81.2 -76.27, -1.53 in-in in 8.695 Saltbr-in 3.1003 HRD-in -69.44, -53.9 82.33, -6.84 in-in-out SNCiio in-out ActLoopNT-in 2.9193 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiio APE10-dihe-na -80.58, 119.04 APE9-dihe-na -87.45, -57.23 APE8-dihe-in -48.06, 132.7 APE8-rot-in 311.02 APE67-dihe-in -70.61, -33.55 -106.57, -39.76 APE12-dist-out 6.5319 APE11-dist-in 9.2949 APE10-dist-in 7.4909 APE9-dist-out 8.1688 None None None XRAY 3.15 0.163 0.218 A 348.0 345.0 0 25 25 0 [[27, 311]] 1.0 7cga Homo sapiens CMGC_MAPK12_HUMAN CMGC 4.7e-85 291.4 1.0 301.0 301.0 170 171 172 174 176 56 74 78 150 152 151 153.0 208 195 190 189 188 187 186 185 184 110 Mitogen-activated protein kinase 12

PDB: 7CGA — CMGC MK12_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name