PDB: 6WXN — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 3 75.0% 6WXNA
DFGin BLBtrans 1 25.0% 6WXNB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 6WXNA P00533 699 1014 1210.0 No_ligand No_ligand Inactive DFGin 4.8528 14.0238 BLBplus -126.21, 168.87 69.17, 33.07 -82.8, 162.03 48.79, 88.7 44.39, 44.22 out-out out 13.1146 Saltbr-out 12.7445 HRD-in -70.78, -60.03 85.71, -15.47 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 117.13 APE8-dihe-in -86.46, 71.73 APE8-rot-na 36.97 APE67-dihe-in -76.26, -5.03 -50.8, -39.36 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.1325 T790M,V948R None None XRAY 1.76 0.209 0.235 A 328.0 298.0 16 30 14 16 [[712, 970]] 1.0 6wxn TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WXNC P00533 701 1014 1210.0 UEJ:1301 Type1.5_Front Inactive DFGin 5.149 14.2422 BLBplus -125.79, 168.58 69.11, 30.42 -73.13, 126.76 42.33, 95.66 91.61, -9.41 out-out out 13.5587 Saltbr-out 12.8267 HRD-in -75.25, -56.93 84.93, -23.09 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 128.4 APE8-dihe-in -83.07, 65.64 APE8-rot-na 32.78 APE67-dihe-in -77.0, -5.94 -52.82, -37.74 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.3472 T790M,V948R None None XRAY 1.76 0.209 0.235 C 328.0 286.0 28 30 14 16 [[712, 970]] 1.0 6wxn TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WXND P00533 702 1014 1210.0 UEJ:1101 Type1.5_Front Inactive DFGin 5.0214 14.1502 BLBplus -127.07, 163.26 73.25, 22.29 -63.33, 141.68 45.73, 93.45 80.75, -14.01 out-out out 13.6526 Saltbr-out 13.5985 HRD-in -75.42, -56.41 82.09, -17.01 out-out-none SNCoon out-none ActLoopNT-out 6.6608 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 108.16 APE8-dihe-in -83.51, 70.14 APE8-rot-na 34.07 APE67-dihe-in -73.61, -7.52 -55.72, -38.9 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.723 T790M,V948R None None XRAY 1.76 0.209 0.235 D 328.0 292.0 16 30 17 13 [[712, 970]] 1.0 6wxn TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WXNB P00533 701 1021 1210.0 ANP:1101 ATPlike Inactive DFGin 5.2834 16.2947 BLBtrans -123.51, 174.07 66.96, 19.19 -61.23, 137.15 158.07, 75.44 91.96, -18.66 out-out out 13.5648 Saltbr-out 13.5233 HRD-in -75.09, -55.39 80.46, -8.33 out-out-none SNCoon out-none ActLoopNT-out 6.4801 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, -21.86 APE9-dihe-in -115.99, 110.82 APE8-dihe-in -78.55, 77.75 APE8-rot-na 31.2 APE67-dihe-in -73.85, -5.28 -56.42, -42.95 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 11.8252 APE9-dist-in 7.8441 T790M,V948R None None XRAY 1.76 0.209 0.235 B 328.0 303.0 11 30 19 11 [[712, 970]] 1.0 6wxn TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 6WXN — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 3 75.0% 6WXNA
DFGin BLBtrans 1 25.0% 6WXNB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 6WXNA P00533 699 1014 1210.0 No_ligand No_ligand Inactive DFGin 4.8528 14.0238 BLBplus -126.21, 168.87 69.17, 33.07 -82.8, 162.03 48.79, 88.7 44.39, 44.22 out-out out 13.1146 Saltbr-out 12.7445 HRD-in -70.78, -60.03 85.71, -15.47 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 117.13 APE8-dihe-in -86.46, 71.73 APE8-rot-na 36.97 APE67-dihe-in -76.26, -5.03 -50.8, -39.36 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.1325 T790M,V948R None None XRAY 1.76 0.209 0.235 A 328.0 298.0 16 30 14 16 [[712, 970]] 1.0 6wxn Homo sapiens TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WXNC P00533 701 1014 1210.0 UEJ:1301 Type1.5_Front Inactive DFGin 5.149 14.2422 BLBplus -125.79, 168.58 69.11, 30.42 -73.13, 126.76 42.33, 95.66 91.61, -9.41 out-out out 13.5587 Saltbr-out 12.8267 HRD-in -75.25, -56.93 84.93, -23.09 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 128.4 APE8-dihe-in -83.07, 65.64 APE8-rot-na 32.78 APE67-dihe-in -77.0, -5.94 -52.82, -37.74 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.3472 T790M,V948R None None XRAY 1.76 0.209 0.235 C 328.0 286.0 28 30 14 16 [[712, 970]] 1.0 6wxn Homo sapiens TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WXND P00533 702 1014 1210.0 UEJ:1101 Type1.5_Front Inactive DFGin 5.0214 14.1502 BLBplus -127.07, 163.26 73.25, 22.29 -63.33, 141.68 45.73, 93.45 80.75, -14.01 out-out out 13.6526 Saltbr-out 13.5985 HRD-in -75.42, -56.41 82.09, -17.01 out-out-none SNCoon out-none ActLoopNT-out 6.6608 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 108.16 APE8-dihe-in -83.51, 70.14 APE8-rot-na 34.07 APE67-dihe-in -73.61, -7.52 -55.72, -38.9 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.723 T790M,V948R None None XRAY 1.76 0.209 0.235 D 328.0 292.0 16 30 17 13 [[712, 970]] 1.0 6wxn Homo sapiens TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WXNB P00533 701 1021 1210.0 ANP:1101 ATPlike Inactive DFGin 5.2834 16.2947 BLBtrans -123.51, 174.07 66.96, 19.19 -61.23, 137.15 158.07, 75.44 91.96, -18.66 out-out out 13.5648 Saltbr-out 13.5233 HRD-in -75.09, -55.39 80.46, -8.33 out-out-none SNCoon out-none ActLoopNT-out 6.4801 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, -21.86 APE9-dihe-in -115.99, 110.82 APE8-dihe-in -78.55, 77.75 APE8-rot-na 31.2 APE67-dihe-in -73.85, -5.28 -56.42, -42.95 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 11.8252 APE9-dist-in 7.8441 T790M,V948R None None XRAY 1.76 0.209 0.235 B 328.0 303.0 11 30 19 11 [[712, 970]] 1.0 6wxn Homo sapiens TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 6WXN — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name