PDB: 6W3C — OTHER ERN1_HUMAN

Total number of chains: 4
Active chains: 4
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6W3CA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
OTHER ERN1 ERN1_HUMAN 6W3CA O75460 560 964 977.0 No_ligand No_ligand Active DFGin 6.1058 14.2357 BLAminus -143.3, -169.77 61.92, 75.26 -99.59, 5.17 293.74, 80.96 -57.56, -26.8 in-in in 8.19 Saltbr-in 2.4383 HRD-in -73.83, -48.09 71.71, -9.73 in-in-in SNCiii in-in ActLoopNT-in 2.8021 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -71.3, -33.45 APE9-dihe-na -62.43, 169.01 APE8-dihe-in -93.38, 133.53 APE8-rot-in 300.11 APE67-dihe-inflip 106.95, -8.39 -49.76, 124.1 APE12-dist-in 11.2447 APE11-dist-in 11.3955 APE10-dist-in 5.4301 APE9-dist-in 3.4493 None SEP724,SEP726,SEP729 SEP724,SEP726,SEP729 XRAY 2.3 0.208 0.248 A 434.0 405.0 0 31 31 0 [[571, 832]] 1.0 6w3c OTHER_ERN1_HUMAN CAMK 3.4e-35 127.8 5.0 256.0 252.0 710 711 712 714 716 599 612 616 685 687 686 688.0 756 741 736 735 734 733 732 731 730 643 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 6W3CB O75460 560 963 977.0 No_ligand No_ligand Active DFGin 6.1058 14.899 BLAminus -154.48, -168.03 55.85, 78.98 -100.05, 13.54 285.56, 16.26 -60.83, -29.52 in-in in 8.3655 Saltbr-in 2.6337 HRD-in -75.16, -45.21 69.8, 0.87 in-in-in SNCiii in-in ActLoopNT-in 2.7083 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -79.23, 157.93 APE9-dihe-na 117.83, 146.57 APE8-dihe-in -81.19, 135.69 APE8-rot-in 308.77 APE67-dihe-inflip 111.32, -6.95 -54.24, 124.62 APE12-dist-in 10.8874 APE11-dist-in 10.8973 APE10-dist-in 4.9571 APE9-dist-in 3.5412 None SEP724,SEP726,SEP729 SEP724,SEP726,SEP729 XRAY 2.3 0.208 0.248 B 434.0 404.0 0 31 31 0 [[571, 832]] 1.0 6w3c OTHER_ERN1_HUMAN CAMK 3.4e-35 127.8 5.0 256.0 252.0 710 711 712 714 716 599 612 616 685 687 686 688.0 756 741 736 735 734 733 732 731 730 643 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 6W3CC O75460 560 963 977.0 No_ligand No_ligand Active DFGin 5.657 15.0187 BLAminus -147.84, -172.12 60.8, 76.5 -95.31, 10.61 280.4, 53.86 -59.0, -26.79 in-in in 8.706 Saltbr-in 2.7208 HRD-in -80.88, -50.26 69.52, 4.83 in-in-in SNCiii in-in ActLoopNT-in 2.9577 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -79.43, 153.53 APE9-dihe-na 125.25, 174.09 APE8-dihe-in -105.72, 131.11 APE8-rot-in 300.67 APE67-dihe-inflip 110.66, -4.8 -51.94, 122.81 APE12-dist-in 11.2388 APE11-dist-in 11.1201 APE10-dist-in 5.2179 APE9-dist-in 3.6747 None SEP724,SEP726,SEP729 SEP724,SEP726,SEP729 XRAY 2.3 0.208 0.248 C 434.0 404.0 0 31 31 0 [[571, 832]] 1.0 6w3c OTHER_ERN1_HUMAN CAMK 3.4e-35 127.8 5.0 256.0 252.0 710 711 712 714 716 599 612 616 685 687 686 688.0 756 741 736 735 734 733 732 731 730 643 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 6W3CD O75460 560 963 977.0 No_ligand No_ligand Active DFGin 5.9323 15.058 BLAminus -157.54, -163.82 60.31, 71.97 -98.14, 3.34 281.98, 17.28 -56.04, -29.73 in-in in 8.6424 Saltbr-in 2.7148 HRD-in -75.91, -46.58 71.49, -6.58 in-in-in SNCiii in-in ActLoopNT-in 2.71 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -80.66, -18.6 APE9-dihe-na -64.06, 167.42 APE8-dihe-in -92.49, 134.25 APE8-rot-in 304.43 APE67-dihe-inflip 103.66, -4.02 -51.74, 125.98 APE12-dist-in 11.3016 APE11-dist-in 11.2182 APE10-dist-in 5.2576 APE9-dist-in 3.4824 None SEP724,SEP726,SEP729 SEP724,SEP726,SEP729 XRAY 2.3 0.208 0.248 D 434.0 404.0 0 31 31 0 [[571, 832]] 1.0 6w3c OTHER_ERN1_HUMAN CAMK 3.4e-35 127.8 5.0 256.0 252.0 710 711 712 714 716 599 612 616 685 687 686 688.0 756 741 736 735 734 733 732 731 730 643 Serine/threonine-protein kinase/endoribonuclease IRE1

PDB: 6W3C — OTHER ERN1_HUMAN

Total number of chains: 4
Active chains: 4
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6W3CA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
OTHER ERN1 ERN1_HUMAN 6W3CA O75460 560 964 977.0 No_ligand No_ligand Active DFGin 6.1058 14.2357 BLAminus -143.3, -169.77 61.92, 75.26 -99.59, 5.17 293.74, 80.96 -57.56, -26.8 in-in in 8.19 Saltbr-in 2.4383 HRD-in -73.83, -48.09 71.71, -9.73 in-in-in SNCiii in-in ActLoopNT-in 2.8021 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -71.3, -33.45 APE9-dihe-na -62.43, 169.01 APE8-dihe-in -93.38, 133.53 APE8-rot-in 300.11 APE67-dihe-inflip 106.95, -8.39 -49.76, 124.1 APE12-dist-in 11.2447 APE11-dist-in 11.3955 APE10-dist-in 5.4301 APE9-dist-in 3.4493 None SEP724,SEP726,SEP729 SEP724,SEP726,SEP729 XRAY 2.3 0.208 0.248 A 434.0 405.0 0 31 31 0 [[571, 832]] 1.0 6w3c Homo sapiens OTHER_ERN1_HUMAN CAMK 3.4e-35 127.8 5.0 256.0 252.0 710 711 712 714 716 599 612 616 685 687 686 688.0 756 741 736 735 734 733 732 731 730 643 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 6W3CB O75460 560 963 977.0 No_ligand No_ligand Active DFGin 6.1058 14.899 BLAminus -154.48, -168.03 55.85, 78.98 -100.05, 13.54 285.56, 16.26 -60.83, -29.52 in-in in 8.3655 Saltbr-in 2.6337 HRD-in -75.16, -45.21 69.8, 0.87 in-in-in SNCiii in-in ActLoopNT-in 2.7083 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -79.23, 157.93 APE9-dihe-na 117.83, 146.57 APE8-dihe-in -81.19, 135.69 APE8-rot-in 308.77 APE67-dihe-inflip 111.32, -6.95 -54.24, 124.62 APE12-dist-in 10.8874 APE11-dist-in 10.8973 APE10-dist-in 4.9571 APE9-dist-in 3.5412 None SEP724,SEP726,SEP729 SEP724,SEP726,SEP729 XRAY 2.3 0.208 0.248 B 434.0 404.0 0 31 31 0 [[571, 832]] 1.0 6w3c Homo sapiens OTHER_ERN1_HUMAN CAMK 3.4e-35 127.8 5.0 256.0 252.0 710 711 712 714 716 599 612 616 685 687 686 688.0 756 741 736 735 734 733 732 731 730 643 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 6W3CC O75460 560 963 977.0 No_ligand No_ligand Active DFGin 5.657 15.0187 BLAminus -147.84, -172.12 60.8, 76.5 -95.31, 10.61 280.4, 53.86 -59.0, -26.79 in-in in 8.706 Saltbr-in 2.7208 HRD-in -80.88, -50.26 69.52, 4.83 in-in-in SNCiii in-in ActLoopNT-in 2.9577 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -79.43, 153.53 APE9-dihe-na 125.25, 174.09 APE8-dihe-in -105.72, 131.11 APE8-rot-in 300.67 APE67-dihe-inflip 110.66, -4.8 -51.94, 122.81 APE12-dist-in 11.2388 APE11-dist-in 11.1201 APE10-dist-in 5.2179 APE9-dist-in 3.6747 None SEP724,SEP726,SEP729 SEP724,SEP726,SEP729 XRAY 2.3 0.208 0.248 C 434.0 404.0 0 31 31 0 [[571, 832]] 1.0 6w3c Homo sapiens OTHER_ERN1_HUMAN CAMK 3.4e-35 127.8 5.0 256.0 252.0 710 711 712 714 716 599 612 616 685 687 686 688.0 756 741 736 735 734 733 732 731 730 643 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 6W3CD O75460 560 963 977.0 No_ligand No_ligand Active DFGin 5.9323 15.058 BLAminus -157.54, -163.82 60.31, 71.97 -98.14, 3.34 281.98, 17.28 -56.04, -29.73 in-in in 8.6424 Saltbr-in 2.7148 HRD-in -75.91, -46.58 71.49, -6.58 in-in-in SNCiii in-in ActLoopNT-in 2.71 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -80.66, -18.6 APE9-dihe-na -64.06, 167.42 APE8-dihe-in -92.49, 134.25 APE8-rot-in 304.43 APE67-dihe-inflip 103.66, -4.02 -51.74, 125.98 APE12-dist-in 11.3016 APE11-dist-in 11.2182 APE10-dist-in 5.2576 APE9-dist-in 3.4824 None SEP724,SEP726,SEP729 SEP724,SEP726,SEP729 XRAY 2.3 0.208 0.248 D 434.0 404.0 0 31 31 0 [[571, 832]] 1.0 6w3c Homo sapiens OTHER_ERN1_HUMAN CAMK 3.4e-35 127.8 5.0 256.0 252.0 710 711 712 714 716 599 612 616 685 687 686 688.0 756 741 736 735 734 733 732 731 730 643 Serine/threonine-protein kinase/endoribonuclease IRE1

PDB: 6W3C — OTHER ERN1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name