| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| OTHER | MLKL | D3ZKP6_RAT | 6VBZA | D3ZKP6 | 183 | 454 | 462.0 | No_ligand | No_ligand | Pseudo | DFGin | 5.8063 | 14.6179 | BLBminus | -127.94, -150.16 | 82.3, 7.23 | -50.29, 129.54 | 298.11, 127.33 | -134.6, 159.72 | in-in | in | 8.0104 | Saltbr-in | 2.8393 | HRD-naE | -66.14, -44.04 | 96.84, -17.36 | in-none-out | SNCino | none-out | ActLoopNT-none | 999.0 | ActLoopCT-out | nonTYR | APEdihe_aaooi | APEdist_nooo | APE10-dihe-na | -117.57, 160.85 | APE9-dihe-na | -74.63, 135.58 | APE8-dihe-out | -62.94, -16.08 | APE8-rot-out | 71.09 | APE67-dihe-in | -56.49, -25.33 | -62.02, -19.84 | APE12-dist-none | 999.0 | APE11-dist-out | 22.7775 | APE10-dist-out | 23.1323 | APE9-dist-out | 14.6963 | None | None | None | XRAY | 2.192 | 0.184 | 0.215 | A | 295.0 | 256.0 | 16 | 32 | 16 | 16 | [[190, 454]] | 1.0 | 6vbz | Rattus norvegicus | OTHER_MLKL_RAT | TKL | 1.7e-47 | 168.1 | 6.0 | 265.0 | 260.0 | 335 | 336 | 337 | 339 | 341 | 219 | 239 | 243 | 315 | 317 | 316 | 318.0 | 381 | 367 | 362 | 361 | 360 | 359 | 358 | 357 | 356 | 273 | Mixed lineage kinase domain-like protein |
| OTHER | MLKL | D3ZKP6_RAT | 6VBZB | D3ZKP6 | 182 | 454 | 462.0 | No_ligand | No_ligand | Pseudo | DFGin | 6.646 | 15.8001 | BLBminus | -133.61, 172.11 | 77.91, 57.02 | -87.12, 172.28 | 304.15, 97.39 | -154.58, -167.67 | in-in | in | 7.8259 | Saltbr-in | 2.4305 | HRD-naE | -68.53, -47.34 | 101.45, -26.64 | in-none-out | SNCino | none-out | ActLoopNT-none | 999.0 | ActLoopCT-out | nonTYR | APEdihe_aaooi | APEdist_nooo | APE10-dihe-na | -138.28, 162.06 | APE9-dihe-na | -77.74, 131.79 | APE8-dihe-out | -67.86, -11.53 | APE8-rot-out | 53.7 | APE67-dihe-in | -52.65, -30.9 | -54.76, -23.09 | APE12-dist-none | 999.0 | APE11-dist-out | 27.3241 | APE10-dist-out | 24.9578 | APE9-dist-out | 14.833 | None | None | None | XRAY | 2.192 | 0.184 | 0.215 | B | 295.0 | 256.0 | 17 | 32 | 15 | 17 | [[190, 454]] | 1.0 | 6vbz | Rattus norvegicus | OTHER_MLKL_RAT | TKL | 1.7e-47 | 168.1 | 6.0 | 265.0 | 260.0 | 335 | 336 | 337 | 339 | 341 | 219 | 239 | 243 | 315 | 317 | 316 | 318.0 | 381 | 367 | 362 | 361 | 360 | 359 | 358 | 357 | 356 | 273 | Mixed lineage kinase domain-like protein |
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| OTHER | MLKL | D3ZKP6_RAT | 6VBZA | D3ZKP6 | 183 | 454 | 462.0 | No_ligand | No_ligand | Pseudo | DFGin | 5.8063 | 14.6179 | BLBminus | -127.94, -150.16 | 82.3, 7.23 | -50.29, 129.54 | 298.11, 127.33 | -134.6, 159.72 | in-in | in | 8.0104 | Saltbr-in | 2.8393 | HRD-naE | -66.14, -44.04 | 96.84, -17.36 | in-none-out | SNCino | none-out | ActLoopNT-none | 999.0 | ActLoopCT-out | nonTYR | APEdihe_aaooi | APEdist_nooo | APE10-dihe-na | -117.57, 160.85 | APE9-dihe-na | -74.63, 135.58 | APE8-dihe-out | -62.94, -16.08 | APE8-rot-out | 71.09 | APE67-dihe-in | -56.49, -25.33 | -62.02, -19.84 | APE12-dist-none | 999.0 | APE11-dist-out | 22.7775 | APE10-dist-out | 23.1323 | APE9-dist-out | 14.6963 | None | None | None | XRAY | 2.192 | 0.184 | 0.215 | A | 295.0 | 256.0 | 16 | 32 | 16 | 16 | [[190, 454]] | 1.0 | 6vbz | Rattus norvegicus | OTHER_MLKL_RAT | TKL | 1.7e-47 | 168.1 | 6.0 | 265.0 | 260.0 | 335 | 336 | 337 | 339 | 341 | 219 | 239 | 243 | 315 | 317 | 316 | 318.0 | 381 | 367 | 362 | 361 | 360 | 359 | 358 | 357 | 356 | 273 | Mixed lineage kinase domain-like protein |
| OTHER | MLKL | D3ZKP6_RAT | 6VBZB | D3ZKP6 | 182 | 454 | 462.0 | No_ligand | No_ligand | Pseudo | DFGin | 6.646 | 15.8001 | BLBminus | -133.61, 172.11 | 77.91, 57.02 | -87.12, 172.28 | 304.15, 97.39 | -154.58, -167.67 | in-in | in | 7.8259 | Saltbr-in | 2.4305 | HRD-naE | -68.53, -47.34 | 101.45, -26.64 | in-none-out | SNCino | none-out | ActLoopNT-none | 999.0 | ActLoopCT-out | nonTYR | APEdihe_aaooi | APEdist_nooo | APE10-dihe-na | -138.28, 162.06 | APE9-dihe-na | -77.74, 131.79 | APE8-dihe-out | -67.86, -11.53 | APE8-rot-out | 53.7 | APE67-dihe-in | -52.65, -30.9 | -54.76, -23.09 | APE12-dist-none | 999.0 | APE11-dist-out | 27.3241 | APE10-dist-out | 24.9578 | APE9-dist-out | 14.833 | None | None | None | XRAY | 2.192 | 0.184 | 0.215 | B | 295.0 | 256.0 | 17 | 32 | 15 | 17 | [[190, 454]] | 1.0 | 6vbz | Rattus norvegicus | OTHER_MLKL_RAT | TKL | 1.7e-47 | 168.1 | 6.0 | 265.0 | 260.0 | 335 | 336 | 337 | 339 | 341 | 219 | 239 | 243 | 315 | 317 | 316 | 318.0 | 381 | 367 | 362 | 361 | 360 | 359 | 358 | 357 | 356 | 273 | Mixed lineage kinase domain-like protein |