PDB: 6V6K — TYR EGFR_HUMAN

Total number of chains: 8
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 5 62.5% 6V6KD
DFGin BLBtrans 3 37.5% 6V6KH
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 6V6KA P00533 700 1014 1210.0 QQJ:1202 Type1 Inactive DFGin 3.8674 13.8443 BLBplus -126.62, 172.08 72.11, 17.73 -68.46, 144.29 67.31, 94.55 80.98, -14.27 out-out out 14.0685 Saltbr-out 13.1175 HRD-in -76.25, -55.46 78.72, -10.68 out-out-none SNCoon out-none ActLoopNT-out 6.607 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 122.92 APE8-dihe-in -90.83, 73.86 APE8-rot-na 33.95 APE67-dihe-in -71.2, -5.54 -52.83, -43.83 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.9809 T790M,V948R None None XRAY 2.2 0.215 0.239 A 327.0 300.0 13 30 17 13 [[712, 970]] 1.0 6v6k TYR_EGFR_HUMAN TYR 6e-88 300.6 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6KC P00533 700 1014 1210.0 QQJ:1202 Type1 Inactive DFGin 3.742 14.114 BLBplus -126.65, 174.74 68.29, 24.91 -77.8, 144.03 65.82, 93.11 70.95, 0.99 out-out out 14.1126 Saltbr-out 13.3204 HRD-in -74.46, -61.55 88.29, -10.53 out-out-none SNCoon out-none ActLoopNT-out 6.895 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 122.13 APE8-dihe-in -80.16, 64.39 APE8-rot-na 34.44 APE67-dihe-in -74.67, -2.44 -48.42, -47.67 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.9081 T790M,V948R None None XRAY 2.2 0.215 0.239 C 327.0 302.0 13 30 17 13 [[712, 970]] 1.0 6v6k TYR_EGFR_HUMAN TYR 6e-88 300.6 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6KD P00533 701 1014 1210.0 QQJ:1202 Type1 Inactive DFGin 3.3493 14.9397 BLBplus -117.8, 170.46 73.04, 20.38 -74.63, 149.6 91.38, 90.72 79.09, -12.98 out-out out 13.99 Saltbr-out 13.4462 HRD-in -72.66, -55.83 84.51, -14.82 out-out-out SNCooo out-out ActLoopNT-out 6.7127 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -109.51, 1.42 APE9-dihe-in -116.89, 115.01 APE8-dihe-in -75.54, 67.0 APE8-rot-na 30.88 APE67-dihe-in -77.85, 1.7 -51.8, -42.48 APE12-dist-na 17.5693 APE11-dist-na 15.0057 APE10-dist-na 10.8891 APE9-dist-in 7.7889 T790M,V948R None None XRAY 2.2 0.215 0.239 D 327.0 314.0 0 30 30 0 [[712, 970]] 1.0 6v6k TYR_EGFR_HUMAN TYR 6e-88 300.6 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6KF P00533 701 1014 1210.0 QQJ:1202 Type1 Inactive DFGin 3.9803 13.825 BLBplus -120.93, 173.29 72.83, 17.47 -73.23, 142.03 63.46, 93.26 87.26, -10.56 out-out out 13.9944 Saltbr-out 13.9231 HRD-in -64.5, -59.24 85.68, -12.32 out-out-out SNCooo out-out ActLoopNT-out 6.8081 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaao APE10-dihe-out -89.94, 8.75 APE9-dihe-in -116.9, 120.13 APE8-dihe-in -80.85, 65.83 APE8-rot-na 33.37 APE67-dihe-in -73.94, -2.38 -51.14, -44.1 APE12-dist-na 18.1488 APE11-dist-na 15.6018 APE10-dist-na 11.4666 APE9-dist-out 8.1427 T790M,V948R None None XRAY 2.2 0.215 0.239 F 327.0 306.0 8 30 22 8 [[712, 970]] 1.0 6v6k TYR_EGFR_HUMAN TYR 6e-88 300.6 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6KG P00533 701 1014 1210.0 QQJ:1202 Type1 Inactive DFGin 3.8748 13.9502 BLBplus -130.73, 172.58 73.14, 20.78 -75.62, 138.08 60.03, 93.12 84.61, -15.28 out-out out 14.0362 Saltbr-out 14.6146 HRD-in -71.13, -52.8 79.1, -13.85 out-out-out SNCooo out-out ActLoopNT-out 6.4699 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -102.69, -0.28 APE9-dihe-in -105.61, 125.6 APE8-dihe-in -80.99, 60.63 APE8-rot-na 33.61 APE67-dihe-in -75.24, -7.52 -47.39, -44.79 APE12-dist-na 18.1857 APE11-dist-na 15.8593 APE10-dist-na 11.4165 APE9-dist-in 7.9334 T790M,V948R None None XRAY 2.2 0.215 0.239 G 327.0 314.0 0 30 30 0 [[712, 970]] 1.0 6v6k TYR_EGFR_HUMAN TYR 6e-88 300.6 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6KB P00533 700 1014 1210.0 QQJ:1202 Type1 Inactive DFGin 5.446 16.6769 BLBtrans -120.08, 174.38 67.53, 23.96 -61.85, 141.71 152.32, 75.87 78.49, -9.92 out-out out 13.7992 Saltbr-out 12.4592 HRD-in -73.15, -55.56 80.97, -11.2 out-out-none SNCoon out-none ActLoopNT-out 6.7927 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 70.83 APE8-rot-na 32.65 APE67-dihe-in -71.54, -3.4 -53.97, -47.47 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 T790M,V948R None None XRAY 2.2 0.215 0.239 B 327.0 301.0 14 30 16 14 [[712, 970]] 1.0 6v6k TYR_EGFR_HUMAN TYR 6e-88 300.6 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6KE P00533 701 1014 1210.0 QQJ:1202 Type1 Inactive DFGin 5.0914 16.0307 BLBtrans -122.64, 177.93 70.8, 11.32 -64.29, 136.62 145.68, 77.64 104.91, -23.54 out-out out 13.5659 Saltbr-out 12.95 HRD-in -74.97, -57.13 87.56, -9.8 out-out-none SNCoon out-none ActLoopNT-out 6.785 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 103.34 APE8-dihe-in -72.02, 69.2 APE8-rot-na 28.12 APE67-dihe-in -72.14, 1.74 -55.9, -45.03 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.9537 T790M,V948R None None XRAY 2.2 0.215 0.239 E 327.0 303.0 11 30 19 11 [[712, 970]] 1.0 6v6k TYR_EGFR_HUMAN TYR 6e-88 300.6 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6KH P00533 701 1014 1210.0 QQJ:1202 Type1 Inactive DFGin 5.3802 16.6173 BLBtrans -122.23, -176.76 60.52, 24.13 -72.16, 137.8 149.6, 82.13 84.24, -7.03 out-out out 14.4629 Saltbr-out 16.5681 HRD-in -71.15, -55.32 82.36, -11.57 out-out-out SNCooo out-out ActLoopNT-out 6.5323 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaao APE10-dihe-out -89.11, -2.11 APE9-dihe-in -99.5, 119.67 APE8-dihe-in -81.25, 72.47 APE8-rot-na 35.55 APE67-dihe-in -80.47, -1.73 -53.94, -37.54 APE12-dist-na 18.7046 APE11-dist-na 16.0276 APE10-dist-na 11.677 APE9-dist-out 8.1135 T790M,V948R None None XRAY 2.2 0.215 0.239 H 327.0 314.0 0 30 30 0 [[712, 970]] 1.0 6v6k TYR_EGFR_HUMAN TYR 6e-88 300.6 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 6V6K — TYR EGFR_HUMAN

Total number of chains: 8
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 5 62.5% 6V6KD
DFGin BLBtrans 3 37.5% 6V6KH
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 6V6KA P00533 700 1014 1210.0 QQJ:1202 Type1 Inactive DFGin 3.8674 13.8443 BLBplus -126.62, 172.08 72.11, 17.73 -68.46, 144.29 67.31, 94.55 80.98, -14.27 out-out out 14.0685 Saltbr-out 13.1175 HRD-in -76.25, -55.46 78.72, -10.68 out-out-none SNCoon out-none ActLoopNT-out 6.607 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 122.92 APE8-dihe-in -90.83, 73.86 APE8-rot-na 33.95 APE67-dihe-in -71.2, -5.54 -52.83, -43.83 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.9809 T790M,V948R None None XRAY 2.2 0.215 0.239 A 327.0 300.0 13 30 17 13 [[712, 970]] 1.0 6v6k Homo sapiens TYR_EGFR_HUMAN TYR 6e-88 300.6 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6KC P00533 700 1014 1210.0 QQJ:1202 Type1 Inactive DFGin 3.742 14.114 BLBplus -126.65, 174.74 68.29, 24.91 -77.8, 144.03 65.82, 93.11 70.95, 0.99 out-out out 14.1126 Saltbr-out 13.3204 HRD-in -74.46, -61.55 88.29, -10.53 out-out-none SNCoon out-none ActLoopNT-out 6.895 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 122.13 APE8-dihe-in -80.16, 64.39 APE8-rot-na 34.44 APE67-dihe-in -74.67, -2.44 -48.42, -47.67 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.9081 T790M,V948R None None XRAY 2.2 0.215 0.239 C 327.0 302.0 13 30 17 13 [[712, 970]] 1.0 6v6k Homo sapiens TYR_EGFR_HUMAN TYR 6e-88 300.6 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6KD P00533 701 1014 1210.0 QQJ:1202 Type1 Inactive DFGin 3.3493 14.9397 BLBplus -117.8, 170.46 73.04, 20.38 -74.63, 149.6 91.38, 90.72 79.09, -12.98 out-out out 13.99 Saltbr-out 13.4462 HRD-in -72.66, -55.83 84.51, -14.82 out-out-out SNCooo out-out ActLoopNT-out 6.7127 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -109.51, 1.42 APE9-dihe-in -116.89, 115.01 APE8-dihe-in -75.54, 67.0 APE8-rot-na 30.88 APE67-dihe-in -77.85, 1.7 -51.8, -42.48 APE12-dist-na 17.5693 APE11-dist-na 15.0057 APE10-dist-na 10.8891 APE9-dist-in 7.7889 T790M,V948R None None XRAY 2.2 0.215 0.239 D 327.0 314.0 0 30 30 0 [[712, 970]] 1.0 6v6k Homo sapiens TYR_EGFR_HUMAN TYR 6e-88 300.6 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6KF P00533 701 1014 1210.0 QQJ:1202 Type1 Inactive DFGin 3.9803 13.825 BLBplus -120.93, 173.29 72.83, 17.47 -73.23, 142.03 63.46, 93.26 87.26, -10.56 out-out out 13.9944 Saltbr-out 13.9231 HRD-in -64.5, -59.24 85.68, -12.32 out-out-out SNCooo out-out ActLoopNT-out 6.8081 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaao APE10-dihe-out -89.94, 8.75 APE9-dihe-in -116.9, 120.13 APE8-dihe-in -80.85, 65.83 APE8-rot-na 33.37 APE67-dihe-in -73.94, -2.38 -51.14, -44.1 APE12-dist-na 18.1488 APE11-dist-na 15.6018 APE10-dist-na 11.4666 APE9-dist-out 8.1427 T790M,V948R None None XRAY 2.2 0.215 0.239 F 327.0 306.0 8 30 22 8 [[712, 970]] 1.0 6v6k Homo sapiens TYR_EGFR_HUMAN TYR 6e-88 300.6 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6KG P00533 701 1014 1210.0 QQJ:1202 Type1 Inactive DFGin 3.8748 13.9502 BLBplus -130.73, 172.58 73.14, 20.78 -75.62, 138.08 60.03, 93.12 84.61, -15.28 out-out out 14.0362 Saltbr-out 14.6146 HRD-in -71.13, -52.8 79.1, -13.85 out-out-out SNCooo out-out ActLoopNT-out 6.4699 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -102.69, -0.28 APE9-dihe-in -105.61, 125.6 APE8-dihe-in -80.99, 60.63 APE8-rot-na 33.61 APE67-dihe-in -75.24, -7.52 -47.39, -44.79 APE12-dist-na 18.1857 APE11-dist-na 15.8593 APE10-dist-na 11.4165 APE9-dist-in 7.9334 T790M,V948R None None XRAY 2.2 0.215 0.239 G 327.0 314.0 0 30 30 0 [[712, 970]] 1.0 6v6k Homo sapiens TYR_EGFR_HUMAN TYR 6e-88 300.6 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6KB P00533 700 1014 1210.0 QQJ:1202 Type1 Inactive DFGin 5.446 16.6769 BLBtrans -120.08, 174.38 67.53, 23.96 -61.85, 141.71 152.32, 75.87 78.49, -9.92 out-out out 13.7992 Saltbr-out 12.4592 HRD-in -73.15, -55.56 80.97, -11.2 out-out-none SNCoon out-none ActLoopNT-out 6.7927 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 70.83 APE8-rot-na 32.65 APE67-dihe-in -71.54, -3.4 -53.97, -47.47 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 T790M,V948R None None XRAY 2.2 0.215 0.239 B 327.0 301.0 14 30 16 14 [[712, 970]] 1.0 6v6k Homo sapiens TYR_EGFR_HUMAN TYR 6e-88 300.6 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6KE P00533 701 1014 1210.0 QQJ:1202 Type1 Inactive DFGin 5.0914 16.0307 BLBtrans -122.64, 177.93 70.8, 11.32 -64.29, 136.62 145.68, 77.64 104.91, -23.54 out-out out 13.5659 Saltbr-out 12.95 HRD-in -74.97, -57.13 87.56, -9.8 out-out-none SNCoon out-none ActLoopNT-out 6.785 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 103.34 APE8-dihe-in -72.02, 69.2 APE8-rot-na 28.12 APE67-dihe-in -72.14, 1.74 -55.9, -45.03 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.9537 T790M,V948R None None XRAY 2.2 0.215 0.239 E 327.0 303.0 11 30 19 11 [[712, 970]] 1.0 6v6k Homo sapiens TYR_EGFR_HUMAN TYR 6e-88 300.6 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6KH P00533 701 1014 1210.0 QQJ:1202 Type1 Inactive DFGin 5.3802 16.6173 BLBtrans -122.23, -176.76 60.52, 24.13 -72.16, 137.8 149.6, 82.13 84.24, -7.03 out-out out 14.4629 Saltbr-out 16.5681 HRD-in -71.15, -55.32 82.36, -11.57 out-out-out SNCooo out-out ActLoopNT-out 6.5323 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaao APE10-dihe-out -89.11, -2.11 APE9-dihe-in -99.5, 119.67 APE8-dihe-in -81.25, 72.47 APE8-rot-na 35.55 APE67-dihe-in -80.47, -1.73 -53.94, -37.54 APE12-dist-na 18.7046 APE11-dist-na 16.0276 APE10-dist-na 11.677 APE9-dist-out 8.1135 T790M,V948R None None XRAY 2.2 0.215 0.239 H 327.0 314.0 0 30 30 0 [[712, 970]] 1.0 6v6k Homo sapiens TYR_EGFR_HUMAN TYR 6e-88 300.6 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 6V6K — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name