PDB: 6UAN — TKL BRAF_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 6UANC
DFGin BLAplus 1 50.0% 6UANB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL BRAF BRAF_HUMAN 6UANC P15056 449 733 766.0 No_ligand No_ligand Inactive DFGin 6.7222 15.086 BLAminus -133.66, -145.42 58.01, 67.46 -89.23, 29.8 285.54, 141.38 -68.94, -15.87 in-out in 9.4531 Saltbr-out 5.3507 HRD-out -71.43, 94.34 -71.05, -36.25 out-in-out SNCoio in-out ActLoopNT-in 2.9419 ActLoopCT-out nonTYR APEdihe_aaini APEdist_iioo APE10-dihe-na -159.48, 168.73 APE9-dihe-na -90.57, 11.03 APE8-dihe-in -91.34, 50.74 APE8-rot-none 999.0 APE67-dihe-in -76.53, -9.36 -80.03, -36.5 APE12-dist-in 13.3742 APE11-dist-in 12.6371 APE10-dist-out 10.0056 APE9-dist-out 11.6186 T373C,I374M SEP729 SEP729 EM 3.9 999.0 999.0 C 768.0 285.0 0 30 30 0 [[457, 716]] 1.0 6uan TKL_BRAF_HUMAN TKL 1.3e-80 277.1 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6UANB P15056 449 750 766.0 No_ligand No_ligand Inactive DFGin 6.0865 12.6357 BLAplus -154.71, 179.74 58.46, 43.55 -98.79, 69.87 37.99, 91.03 -71.09, -56.22 in-out in 9.5942 Saltbr-out 7.4833 HRD-in -73.07, -51.77 71.88, -8.56 out-in-none SNCoin in-none ActLoopNT-in 3.2329 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none 999.0, 999.0 999.0, 999.0 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 T373C,I374M SEP729 SEP729 EM 3.9 999.0 999.0 B 768.0 261.0 41 30 9 21 [[457, 716]] 1.0 6uan TKL_BRAF_HUMAN TKL 1.3e-80 277.1 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf

PDB: 6UAN — TKL BRAF_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 6UANC
DFGin BLAplus 1 50.0% 6UANB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL BRAF BRAF_HUMAN 6UANC P15056 449 733 766.0 No_ligand No_ligand Inactive DFGin 6.7222 15.086 BLAminus -133.66, -145.42 58.01, 67.46 -89.23, 29.8 285.54, 141.38 -68.94, -15.87 in-out in 9.4531 Saltbr-out 5.3507 HRD-out -71.43, 94.34 -71.05, -36.25 out-in-out SNCoio in-out ActLoopNT-in 2.9419 ActLoopCT-out nonTYR APEdihe_aaini APEdist_iioo APE10-dihe-na -159.48, 168.73 APE9-dihe-na -90.57, 11.03 APE8-dihe-in -91.34, 50.74 APE8-rot-none 999.0 APE67-dihe-in -76.53, -9.36 -80.03, -36.5 APE12-dist-in 13.3742 APE11-dist-in 12.6371 APE10-dist-out 10.0056 APE9-dist-out 11.6186 T373C,I374M SEP729 SEP729 EM 3.9 999.0 999.0 C 768.0 285.0 0 30 30 0 [[457, 716]] 1.0 6uan Homo sapiens TKL_BRAF_HUMAN TKL 1.3e-80 277.1 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6UANB P15056 449 750 766.0 No_ligand No_ligand Inactive DFGin 6.0865 12.6357 BLAplus -154.71, 179.74 58.46, 43.55 -98.79, 69.87 37.99, 91.03 -71.09, -56.22 in-out in 9.5942 Saltbr-out 7.4833 HRD-in -73.07, -51.77 71.88, -8.56 out-in-none SNCoin in-none ActLoopNT-in 3.2329 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none 999.0, 999.0 999.0, 999.0 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 T373C,I374M SEP729 SEP729 EM 3.9 999.0 999.0 B 768.0 261.0 41 30 9 21 [[457, 716]] 1.0 6uan Homo sapiens TKL_BRAF_HUMAN TKL 1.3e-80 277.1 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf

PDB: 6UAN — TKL BRAF_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name