PDB: 6RFJ — TKL IRAK4_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 6RFJB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 6RFJA Q9NWZ3 165 458 460.0 K1E:501 Type1 Inactive DFGin 6.7312 14.2145 BLAminus -138.26, 177.45 62.01, 88.8 -111.36, 12.54 307.73, 96.46 -63.8, -18.03 in-out in 8.9085 Saltbr-out 4.5689 HRD-in -70.21, -47.87 75.12, -3.47 out-in-in SNCoii in-in ActLoopNT-in 2.7494 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -122.34, 157.08 APE9-dihe-na 130.62, -174.05 APE8-dihe-in -112.58, 112.94 APE8-rot-in 303.06 APE67-dihe-in -64.16, -16.63 -45.12, -46.37 APE12-dist-in 9.991 APE11-dist-in 11.846 APE10-dist-in 6.2324 APE9-dist-in 3.6713 None TPO345,SEP346 TPO345,SEP346 XRAY 2.61 0.245 0.254 A 322.0 268.0 26 30 23 7 [[183, 456]] 1.0 6rfj TKL_IRAK4_HUMAN TKL 5.2e-84 287.9 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6RFJB Q9NWZ3 164 458 460.0 K1E:502 Type1 Inactive DFGin 6.98 14.2477 BLAminus -131.73, 178.64 60.17, 79.36 -102.97, 22.96 313.3, 93.8 -64.31, -22.35 in-out in 9.0016 Saltbr-out 4.973 HRD-in -70.9, -51.42 81.49, -4.07 out-in-in SNCoii in-in ActLoopNT-in 2.7843 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -119.43, 154.68 APE9-dihe-na 135.37, -174.43 APE8-dihe-in -109.42, 116.51 APE8-rot-in 308.77 APE67-dihe-in -61.15, -17.08 -52.21, -44.98 APE12-dist-in 10.1202 APE11-dist-in 11.8217 APE10-dist-in 6.2407 APE9-dist-in 3.8303 None TPO345,SEP346 TPO345,SEP346 XRAY 2.61 0.245 0.254 B 322.0 279.0 16 30 22 8 [[183, 456]] 1.0 6rfj TKL_IRAK4_HUMAN TKL 5.2e-84 287.9 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

PDB: 6RFJ — TKL IRAK4_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 6RFJB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 6RFJA Q9NWZ3 165 458 460.0 K1E:501 Type1 Inactive DFGin 6.7312 14.2145 BLAminus -138.26, 177.45 62.01, 88.8 -111.36, 12.54 307.73, 96.46 -63.8, -18.03 in-out in 8.9085 Saltbr-out 4.5689 HRD-in -70.21, -47.87 75.12, -3.47 out-in-in SNCoii in-in ActLoopNT-in 2.7494 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -122.34, 157.08 APE9-dihe-na 130.62, -174.05 APE8-dihe-in -112.58, 112.94 APE8-rot-in 303.06 APE67-dihe-in -64.16, -16.63 -45.12, -46.37 APE12-dist-in 9.991 APE11-dist-in 11.846 APE10-dist-in 6.2324 APE9-dist-in 3.6713 None TPO345,SEP346 TPO345,SEP346 XRAY 2.61 0.245 0.254 A 322.0 268.0 26 30 23 7 [[183, 456]] 1.0 6rfj Homo sapiens TKL_IRAK4_HUMAN TKL 5.2e-84 287.9 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6RFJB Q9NWZ3 164 458 460.0 K1E:502 Type1 Inactive DFGin 6.98 14.2477 BLAminus -131.73, 178.64 60.17, 79.36 -102.97, 22.96 313.3, 93.8 -64.31, -22.35 in-out in 9.0016 Saltbr-out 4.973 HRD-in -70.9, -51.42 81.49, -4.07 out-in-in SNCoii in-in ActLoopNT-in 2.7843 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -119.43, 154.68 APE9-dihe-na 135.37, -174.43 APE8-dihe-in -109.42, 116.51 APE8-rot-in 308.77 APE67-dihe-in -61.15, -17.08 -52.21, -44.98 APE12-dist-in 10.1202 APE11-dist-in 11.8217 APE10-dist-in 6.2407 APE9-dist-in 3.8303 None TPO345,SEP346 TPO345,SEP346 XRAY 2.61 0.245 0.254 B 322.0 279.0 16 30 22 8 [[183, 456]] 1.0 6rfj Homo sapiens TKL_IRAK4_HUMAN TKL 5.2e-84 287.9 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

PDB: 6RFJ — TKL IRAK4_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name