PDB: 6RFI — TKL IRAK4_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 6RFIB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 6RFIA Q9NWZ3 165 458 460.0 K1H:502 Type1 Inactive DFGin 6.9898 14.3021 BLAminus -129.16, 176.7 63.09, 88.81 -109.76, 14.57 309.19, 95.71 -60.71, -34.41 in-out in 8.9539 Saltbr-out 4.6447 HRD-in -64.1, -51.33 77.3, -1.49 out-in-in SNCoii in-in ActLoopNT-in 2.9423 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -129.51, 158.58 APE9-dihe-na 128.54, -171.69 APE8-dihe-in -107.47, 116.44 APE8-rot-in 316.16 APE67-dihe-in -66.19, -16.15 -43.18, -47.25 APE12-dist-in 10.0116 APE11-dist-in 11.8198 APE10-dist-in 6.3514 APE9-dist-in 3.7063 None TPO345,SEP346 TPO345,SEP346 XRAY 2.31 0.211 0.236 A 322.0 275.0 19 30 25 5 [[183, 456]] 1.0 6rfi TKL_IRAK4_HUMAN TKL 5.2e-84 287.9 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6RFIB Q9NWZ3 164 458 460.0 K1H:502 Type1 Inactive DFGin 7.0642 14.0503 BLAminus -129.63, 173.33 61.36, 88.99 -110.28, 17.12 308.46, 99.08 -63.95, -28.47 in-out in 8.8564 Saltbr-out 4.3159 HRD-in -66.26, -50.83 78.99, -1.16 out-in-in SNCoii in-in ActLoopNT-in 2.7779 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -126.66, 154.17 APE9-dihe-na 132.35, -169.11 APE8-dihe-in -111.83, 120.53 APE8-rot-in 311.0 APE67-dihe-in -70.4, -14.87 -59.89, -31.07 APE12-dist-in 10.04 APE11-dist-in 11.875 APE10-dist-in 6.3304 APE9-dist-in 3.7215 None TPO345,SEP346 TPO345,SEP346 XRAY 2.31 0.211 0.236 B 322.0 280.0 15 30 22 8 [[183, 456]] 1.0 6rfi TKL_IRAK4_HUMAN TKL 5.2e-84 287.9 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

PDB: 6RFI — TKL IRAK4_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 6RFIB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 6RFIA Q9NWZ3 165 458 460.0 K1H:502 Type1 Inactive DFGin 6.9898 14.3021 BLAminus -129.16, 176.7 63.09, 88.81 -109.76, 14.57 309.19, 95.71 -60.71, -34.41 in-out in 8.9539 Saltbr-out 4.6447 HRD-in -64.1, -51.33 77.3, -1.49 out-in-in SNCoii in-in ActLoopNT-in 2.9423 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -129.51, 158.58 APE9-dihe-na 128.54, -171.69 APE8-dihe-in -107.47, 116.44 APE8-rot-in 316.16 APE67-dihe-in -66.19, -16.15 -43.18, -47.25 APE12-dist-in 10.0116 APE11-dist-in 11.8198 APE10-dist-in 6.3514 APE9-dist-in 3.7063 None TPO345,SEP346 TPO345,SEP346 XRAY 2.31 0.211 0.236 A 322.0 275.0 19 30 25 5 [[183, 456]] 1.0 6rfi Homo sapiens TKL_IRAK4_HUMAN TKL 5.2e-84 287.9 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6RFIB Q9NWZ3 164 458 460.0 K1H:502 Type1 Inactive DFGin 7.0642 14.0503 BLAminus -129.63, 173.33 61.36, 88.99 -110.28, 17.12 308.46, 99.08 -63.95, -28.47 in-out in 8.8564 Saltbr-out 4.3159 HRD-in -66.26, -50.83 78.99, -1.16 out-in-in SNCoii in-in ActLoopNT-in 2.7779 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -126.66, 154.17 APE9-dihe-na 132.35, -169.11 APE8-dihe-in -111.83, 120.53 APE8-rot-in 311.0 APE67-dihe-in -70.4, -14.87 -59.89, -31.07 APE12-dist-in 10.04 APE11-dist-in 11.875 APE10-dist-in 6.3304 APE9-dist-in 3.7215 None TPO345,SEP346 TPO345,SEP346 XRAY 2.31 0.211 0.236 B 322.0 280.0 15 30 22 8 [[183, 456]] 1.0 6rfi Homo sapiens TKL_IRAK4_HUMAN TKL 5.2e-84 287.9 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

PDB: 6RFI — TKL IRAK4_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name