PDB: 6Q0T — 2 kinases

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
None None 3 100.0% 6Q0TA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 6Q0TC Q02750 43 379 393.0 LCJ:60402,AGS:60403 Type1,ATPlike Inactive None 999.0 999.0 None -140.61, 176.69 54.64, 28.33 -81.67, 161.61 999.0, 999.0 -81.74, 73.01 out-none out 15.4983 Saltbr-none 999.0 HRD-in -63.91, -56.51 90.24, -35.06 none-out-out SNCnoo out-out ActLoopNT-out 9.2901 ActLoopCT-out nonTYR APEdihe_aaono APEdist_oooo APE10-dihe-na -73.68, 137.65 APE9-dihe-na -84.71, 179.02 APE8-dihe-out -112.93, -24.43 APE8-rot-none 999.0 APE67-dihe-out -153.47, 146.62 -142.35, -172.44 APE12-dist-out 17.1555 APE11-dist-out 21.6524 APE10-dist-out 23.7974 APE9-dist-out 13.4988 S218A,S222A None None EM 5.7 999.0 999.0 C 414.0 306.0 31 26 26 0 [[68, 361]] 1.0 6q0t STE_MAP2K1_HUMAN STE 1.3e-96 329.0 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL BRAF BRAF_HUMAN 6Q0TA P15056 449 732 766.0 No_ligand No_ligand Inactive None 999.0 999.0 None -125.68, -157.44 46.86, 85.51 -102.96, 25.68 999.0, 999.0 -59.84, -20.53 in-none in 8.8115 Saltbr-none 999.0 HRD-in -72.53, -45.64 70.89, -1.18 none-in-out SNCnio in-out ActLoopNT-in 2.8643 ActLoopCT-out nonTYR APEdihe_aaini APEdist_iioi APE10-dihe-na -136.48, 156.68 APE9-dihe-na 140.41, 169.16 APE8-dihe-in -83.57, 130.55 APE8-rot-none 999.0 APE67-dihe-in -60.84, -19.83 -69.97, -34.72 APE12-dist-in 12.0059 APE11-dist-in 11.4723 APE10-dist-out 8.1134 APE9-dist-in 5.6101 S365A SEP729 SEP729 EM 5.7 999.0 999.0 A 805.0 280.0 4 30 30 0 [[457, 716]] 1.0 6q0t TKL_BRAF_HUMAN TKL 1.4e-80 277.0 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6Q0TB P15056 449 730 766.0 No_ligand No_ligand Inactive None 999.0 999.0 None -125.71, -157.51 46.95, 85.47 -102.88, 25.78 999.0, 999.0 -60.15, -20.42 in-none in 8.8132 Saltbr-none 999.0 HRD-in -72.6, -45.69 70.98, -1.32 none-in-out SNCnio in-out ActLoopNT-in 2.8634 ActLoopCT-out nonTYR APEdihe_aaini APEdist_iioi APE10-dihe-na -136.41, 156.62 APE9-dihe-na 140.41, 169.2 APE8-dihe-in -83.59, 130.6 APE8-rot-none 999.0 APE67-dihe-in -60.82, -19.75 -69.88, -34.94 APE12-dist-in 12.0034 APE11-dist-in 11.4711 APE10-dist-out 8.1128 APE9-dist-in 5.6087 S365A SEP729 SEP729 EM 5.7 999.0 999.0 B 805.0 278.0 4 30 30 0 [[457, 716]] 1.0 6q0t TKL_BRAF_HUMAN TKL 1.4e-80 277.0 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf

PDB: 6Q0T — 2 kinases

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
None None 3 100.0% 6Q0TA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 6Q0TC Q02750 43 379 393.0 LCJ:60402,AGS:60403 Type1,ATPlike Inactive None 999.0 999.0 None -140.61, 176.69 54.64, 28.33 -81.67, 161.61 999.0, 999.0 -81.74, 73.01 out-none out 15.4983 Saltbr-none 999.0 HRD-in -63.91, -56.51 90.24, -35.06 none-out-out SNCnoo out-out ActLoopNT-out 9.2901 ActLoopCT-out nonTYR APEdihe_aaono APEdist_oooo APE10-dihe-na -73.68, 137.65 APE9-dihe-na -84.71, 179.02 APE8-dihe-out -112.93, -24.43 APE8-rot-none 999.0 APE67-dihe-out -153.47, 146.62 -142.35, -172.44 APE12-dist-out 17.1555 APE11-dist-out 21.6524 APE10-dist-out 23.7974 APE9-dist-out 13.4988 S218A,S222A None None EM 5.7 999.0 999.0 C 414.0 306.0 31 26 26 0 [[68, 361]] 1.0 6q0t Homo sapiens STE_MAP2K1_HUMAN STE 1.3e-96 329.0 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL BRAF BRAF_HUMAN 6Q0TA P15056 449 732 766.0 No_ligand No_ligand Inactive None 999.0 999.0 None -125.68, -157.44 46.86, 85.51 -102.96, 25.68 999.0, 999.0 -59.84, -20.53 in-none in 8.8115 Saltbr-none 999.0 HRD-in -72.53, -45.64 70.89, -1.18 none-in-out SNCnio in-out ActLoopNT-in 2.8643 ActLoopCT-out nonTYR APEdihe_aaini APEdist_iioi APE10-dihe-na -136.48, 156.68 APE9-dihe-na 140.41, 169.16 APE8-dihe-in -83.57, 130.55 APE8-rot-none 999.0 APE67-dihe-in -60.84, -19.83 -69.97, -34.72 APE12-dist-in 12.0059 APE11-dist-in 11.4723 APE10-dist-out 8.1134 APE9-dist-in 5.6101 S365A SEP729 SEP729 EM 5.7 999.0 999.0 A 805.0 280.0 4 30 30 0 [[457, 716]] 1.0 6q0t Homo sapiens TKL_BRAF_HUMAN TKL 1.4e-80 277.0 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6Q0TB P15056 449 730 766.0 No_ligand No_ligand Inactive None 999.0 999.0 None -125.71, -157.51 46.95, 85.47 -102.88, 25.78 999.0, 999.0 -60.15, -20.42 in-none in 8.8132 Saltbr-none 999.0 HRD-in -72.6, -45.69 70.98, -1.32 none-in-out SNCnio in-out ActLoopNT-in 2.8634 ActLoopCT-out nonTYR APEdihe_aaini APEdist_iioi APE10-dihe-na -136.41, 156.62 APE9-dihe-na 140.41, 169.2 APE8-dihe-in -83.59, 130.6 APE8-rot-none 999.0 APE67-dihe-in -60.82, -19.75 -69.88, -34.94 APE12-dist-in 12.0034 APE11-dist-in 11.4711 APE10-dist-out 8.1128 APE9-dist-in 5.6087 S365A SEP729 SEP729 EM 5.7 999.0 999.0 B 805.0 278.0 4 30 30 0 [[457, 716]] 1.0 6q0t Homo sapiens TKL_BRAF_HUMAN TKL 1.4e-80 277.0 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf

PDB: 6Q0T — 2 kinases

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name