PDB: 6PNX — TYR FGFR3_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 2 100.0% 6PNXB

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR3 FGFR3_HUMAN 6PNXA P22607 456 757 806.0 ACP:801 ATPlike Inactive DFGin 5.183 13.257 BLAplus -117.43, 165.96 59.53, 36.21 -90.35, -22.61 56.49, 88.29 -100.71, 20.75 in-out in 7.758 Saltbr-out 3.892 HRD-in -72.74, -43.96 72.66, -12.59 out-out-out SNCooo out-out ActLoopNT-out 8.611 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out 61.32, -168.18 APE9-dihe-in -95.45, 138.6 APE8-dihe-in -83.08, 62.92 APE8-rot-na 32.84 APE67-dihe-in -77.59, -4.01 -63.19, -31.79 APE12-dist-na 17.76 APE11-dist-na 14.387 APE10-dist-na 16.475 APE9-dist-in 7.98 C482A,C582S,R669E None None XRAY 2.199 0.195 0.23 A 324 291 11 0 0 0 [[472, 750]] 1.0 6pnx TYR_FGFR3_HUMAN TYR 2.5e-104 354.1 1 260 260 634 635 636 638 640 508 525 529 614 616 615 617 676 664 659 658 657 656 655 654 653 556 Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 6PNXB P22607 455 756 806.0 ACP:801 ATPlike Inactive DFGin 5.102 12.88 BLAplus -116.22, 163.18 57.59, 45.48 -96.33, -11.84 56.51, 88.18 -107.89, 22.55 in-in in 7.372 Saltbr-in 2.381 HRD-in -94.02, -38.66 69.29, -17.12 in-out-out SNCioo out-out ActLoopNT-out 4.149 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out 54.33, 74.29 APE9-dihe-in -157.39, 146.53 APE8-dihe-in -79.85, 92.16 APE8-rot-na 29.38 APE67-dihe-in -64.97, -14.94 -62.55, -40.44 APE12-dist-na 17.529 APE11-dist-na 16.958 APE10-dist-na 14.632 APE9-dist-in 7.491 C482A,C582S,R669E None None XRAY 2.199 0.195 0.23 B 324 294 8 0 0 0 [[472, 750]] 1.0 6pnx TYR_FGFR3_HUMAN TYR 2.5e-104 354.1 1 260 260 634 635 636 638 640 508 525 529 614 616 615 617 676 664 659 658 657 656 655 654 653 556 Fibroblast growth factor receptor 3

PDB: 6PNX — TYR FGFR3_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 2 100.0% 6PNXB

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR3 FGFR3_HUMAN 6PNXA P22607 456 757 806.0 ACP:801 ATPlike Inactive DFGin 5.183 13.257 BLAplus -117.43, 165.96 59.53, 36.21 -90.35, -22.61 56.49, 88.29 -100.71, 20.75 in-out in 7.758 Saltbr-out 3.892 HRD-in -72.74, -43.96 72.66, -12.59 out-out-out SNCooo out-out ActLoopNT-out 8.611 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out 61.32, -168.18 APE9-dihe-in -95.45, 138.6 APE8-dihe-in -83.08, 62.92 APE8-rot-na 32.84 APE67-dihe-in -77.59, -4.01 -63.19, -31.79 APE12-dist-na 17.76 APE11-dist-na 14.387 APE10-dist-na 16.475 APE9-dist-in 7.98 C482A,C582S,R669E None None XRAY 2.199 0.195 0.23 A 324 291 11 0 0 0 [[472, 750]] 1.0 6pnx Homo sapiens TYR_FGFR3_HUMAN TYR 2.5e-104 354.1 1 260 260 634 635 636 638 640 508 525 529 614 616 615 617 676 664 659 658 657 656 655 654 653 556 Fibroblast growth factor receptor 3
TYR FGFR3 FGFR3_HUMAN 6PNXB P22607 455 756 806.0 ACP:801 ATPlike Inactive DFGin 5.102 12.88 BLAplus -116.22, 163.18 57.59, 45.48 -96.33, -11.84 56.51, 88.18 -107.89, 22.55 in-in in 7.372 Saltbr-in 2.381 HRD-in -94.02, -38.66 69.29, -17.12 in-out-out SNCioo out-out ActLoopNT-out 4.149 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out 54.33, 74.29 APE9-dihe-in -157.39, 146.53 APE8-dihe-in -79.85, 92.16 APE8-rot-na 29.38 APE67-dihe-in -64.97, -14.94 -62.55, -40.44 APE12-dist-na 17.529 APE11-dist-na 16.958 APE10-dist-na 14.632 APE9-dist-in 7.491 C482A,C582S,R669E None None XRAY 2.199 0.195 0.23 B 324 294 8 0 0 0 [[472, 750]] 1.0 6pnx Homo sapiens TYR_FGFR3_HUMAN TYR 2.5e-104 354.1 1 260 260 634 635 636 638 640 508 525 529 614 616 615 617 676 664 659 658 657 656 655 654 653 556 Fibroblast growth factor receptor 3

PDB: 6PNX — TYR FGFR3_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name