PDB: 6P8Q — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 4 100.0% 6P8QC

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 6P8QA P00533 699 1019 1210.0 ANP:2001,O57:2002 ATPlike,Type3 Inactive DFGin 5.291 14.467 BLBplus -136.39, 166.39 65.62, 19.67 -68.64, 141.86 47.45, 96.29 88.91, -15.41 out-out out 13.793 Saltbr-out 13.394 HRD-in -77.48, -60.3 86.7, -15.68 out-out-none SNCoon out-none ActLoopNT-out 6.927 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 121.69 APE8-dihe-in -82.28, 70.48 APE8-rot-na 31.78 APE67-dihe-in -69.54, -10.7 -59.7, -40.22 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.523 T790M,V948R None None XRAY 1.9 0.169 0.195 A 327 309 12 0 0 12 [[712, 970]] 1.0 6p8q TYR_EGFR_HUMAN TYR 6e-88 300.6 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6P8QB P00533 698 1007 1210.0 AMP:2001,O57:2002 ATPlike,Type3 Inactive DFGin 5.276 14.467 BLBplus -135.86, 166.31 67.07, 15.83 -64.3, 136.34 50.27, 96.09 85.52, -9.82 out-out out 13.54 Saltbr-out 13.7 HRD-in -74.24, -59.24 89.14, -20.92 out-out-none SNCoon out-none ActLoopNT-out 6.974 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 150.09 APE9-dihe-in -104.23, 113.6 APE8-dihe-in -82.27, 71.52 APE8-rot-na 22.76 APE67-dihe-in -69.35, -13.24 -58.74, -40.13 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 11.877 APE9-dist-in 7.993 T790M,V948R None None XRAY 1.9 0.169 0.195 B 327 300 10 0 0 10 [[712, 970]] 1.0 6p8q TYR_EGFR_HUMAN TYR 6e-88 300.6 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6P8QC P00533 699 1014 1210.0 AMP:2001,O57:2002 ATPlike,Type3 Inactive DFGin 5.309 14.59 BLBplus -130.27, 166.7 65.36, 18.32 -66.06, 140.33 49.17, 97.15 81.91, -12.21 out-out out 13.83 Saltbr-out 13.591 HRD-in -81.24, -59.54 87.32, -15.78 out-out-in SNCooi out-in ActLoopNT-out 6.911 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -63.57, 147.96 APE9-dihe-in -130.06, 156.46 APE8-dihe-in -83.94, 74.96 APE8-rot-na 27.22 APE67-dihe-in -70.93, -14.87 -56.96, -36.77 APE12-dist-na 16.927 APE11-dist-na 13.676 APE10-dist-na 14.094 APE9-dist-in 7.721 T790M,V948R None None XRAY 1.9 0.169 0.195 C 327 316 0 0 0 0 [[712, 970]] 1.0 6p8q TYR_EGFR_HUMAN TYR 6e-88 300.6 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6P8QD P00533 700 1007 1210.0 AMP:2001,O57:2002 ATPlike,Type3 Inactive DFGin 5.367 14.316 BLBplus -131.89, 166.57 70.0, 15.99 -68.19, 140.48 43.77, 99.15 83.83, -10.13 out-out out 13.426 Saltbr-out 13.149 HRD-in -73.29, -58.03 87.0, -17.51 out-out-none SNCoon out-none ActLoopNT-out 6.894 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 92.37 APE8-dihe-in -76.46, 76.63 APE8-rot-na 30.25 APE67-dihe-in -71.2, -11.99 -56.02, -38.06 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.449 T790M,V948R None None XRAY 1.9 0.169 0.195 D 327 296 12 0 0 12 [[712, 970]] 1.0 6p8q TYR_EGFR_HUMAN TYR 6e-88 300.6 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 6P8Q — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 4 100.0% 6P8QC

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 6P8QA P00533 699 1019 1210.0 ANP:2001,O57:2002 ATPlike,Type3 Inactive DFGin 5.291 14.467 BLBplus -136.39, 166.39 65.62, 19.67 -68.64, 141.86 47.45, 96.29 88.91, -15.41 out-out out 13.793 Saltbr-out 13.394 HRD-in -77.48, -60.3 86.7, -15.68 out-out-none SNCoon out-none ActLoopNT-out 6.927 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 121.69 APE8-dihe-in -82.28, 70.48 APE8-rot-na 31.78 APE67-dihe-in -69.54, -10.7 -59.7, -40.22 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.523 T790M,V948R None None XRAY 1.9 0.169 0.195 A 327 309 12 0 0 12 [[712, 970]] 1.0 6p8q Homo sapiens TYR_EGFR_HUMAN TYR 6e-88 300.6 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6P8QB P00533 698 1007 1210.0 AMP:2001,O57:2002 ATPlike,Type3 Inactive DFGin 5.276 14.467 BLBplus -135.86, 166.31 67.07, 15.83 -64.3, 136.34 50.27, 96.09 85.52, -9.82 out-out out 13.54 Saltbr-out 13.7 HRD-in -74.24, -59.24 89.14, -20.92 out-out-none SNCoon out-none ActLoopNT-out 6.974 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 150.09 APE9-dihe-in -104.23, 113.6 APE8-dihe-in -82.27, 71.52 APE8-rot-na 22.76 APE67-dihe-in -69.35, -13.24 -58.74, -40.13 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 11.877 APE9-dist-in 7.993 T790M,V948R None None XRAY 1.9 0.169 0.195 B 327 300 10 0 0 10 [[712, 970]] 1.0 6p8q Homo sapiens TYR_EGFR_HUMAN TYR 6e-88 300.6 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6P8QC P00533 699 1014 1210.0 AMP:2001,O57:2002 ATPlike,Type3 Inactive DFGin 5.309 14.59 BLBplus -130.27, 166.7 65.36, 18.32 -66.06, 140.33 49.17, 97.15 81.91, -12.21 out-out out 13.83 Saltbr-out 13.591 HRD-in -81.24, -59.54 87.32, -15.78 out-out-in SNCooi out-in ActLoopNT-out 6.911 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -63.57, 147.96 APE9-dihe-in -130.06, 156.46 APE8-dihe-in -83.94, 74.96 APE8-rot-na 27.22 APE67-dihe-in -70.93, -14.87 -56.96, -36.77 APE12-dist-na 16.927 APE11-dist-na 13.676 APE10-dist-na 14.094 APE9-dist-in 7.721 T790M,V948R None None XRAY 1.9 0.169 0.195 C 327 316 0 0 0 0 [[712, 970]] 1.0 6p8q Homo sapiens TYR_EGFR_HUMAN TYR 6e-88 300.6 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6P8QD P00533 700 1007 1210.0 AMP:2001,O57:2002 ATPlike,Type3 Inactive DFGin 5.367 14.316 BLBplus -131.89, 166.57 70.0, 15.99 -68.19, 140.48 43.77, 99.15 83.83, -10.13 out-out out 13.426 Saltbr-out 13.149 HRD-in -73.29, -58.03 87.0, -17.51 out-out-none SNCoon out-none ActLoopNT-out 6.894 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 92.37 APE8-dihe-in -76.46, 76.63 APE8-rot-na 30.25 APE67-dihe-in -71.2, -11.99 -56.02, -38.06 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.449 T790M,V948R None None XRAY 1.9 0.169 0.195 D 327 296 12 0 0 12 [[712, 970]] 1.0 6p8q Homo sapiens TYR_EGFR_HUMAN TYR 6e-88 300.6 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 6P8Q — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name