PDB: 6O9D — TKL IRAK4_HUMAN

Total number of chains: 4
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6O9DA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 6O9DA Q9NWZ3 162 458 460.0 LTY:501 Type1 Inactive DFGin 6.707 14.456 BLAminus -127.76, -176.84 57.79, 87.99 -106.68, 3.04 297.04, 103.76 -53.04, -31.02 in-out in 8.335 Saltbr-out 3.618 HRD-in -61.91, -55.52 80.82, -6.22 out-in-in SNCoii in-in ActLoopNT-in 2.796 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -125.17, 155.38 APE9-dihe-na 127.36, -176.8 APE8-dihe-in -102.61, 119.68 APE8-rot-in 323.19 APE67-dihe-in -59.01, -22.88 -47.44, -49.99 APE12-dist-in 9.901 APE11-dist-in 11.599 APE10-dist-in 6.247 APE9-dist-in 3.911 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.51 0.197 0.239 A 320 286 11 0 0 4 [[183, 456]] 1.0 6o9d TKL_IRAK4_HUMAN TKL 5.1e-84 287.9 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6O9DB Q9NWZ3 163 458 460.0 LTY:501 Type1 Inactive DFGin 7.057 13.951 BLAminus -143.03, -179.16 58.94, 82.95 -104.14, 17.08 307.96, 103.48 -62.26, -32.09 in-out in 8.688 Saltbr-out 4.207 HRD-in -62.85, -48.11 75.04, -10.08 out-in-in SNCoii in-in ActLoopNT-in 2.931 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -116.13, 158.27 APE9-dihe-na 134.69, -173.08 APE8-dihe-in -118.39, 112.91 APE8-rot-in 312.26 APE67-dihe-in -64.54, -21.64 -47.5, -39.01 APE12-dist-in 10.134 APE11-dist-in 11.762 APE10-dist-in 6.303 APE9-dist-in 4.078 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.51 0.197 0.239 B 320 284 12 0 0 5 [[183, 456]] 1.0 6o9d TKL_IRAK4_HUMAN TKL 5.1e-84 287.9 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6O9DC Q9NWZ3 163 458 460.0 LTY:501 Type1 Active DFGin 6.921 14.055 BLAminus -144.04, 172.46 65.41, 89.1 -109.46, 16.79 309.79, 96.88 -60.57, -25.46 in-in in 8.638 Saltbr-in 3.243 HRD-in -67.13, -59.39 84.36, 2.8 in-in-in SNCiii in-in ActLoopNT-in 2.917 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -122.08, 166.4 APE9-dihe-na 121.39, -170.65 APE8-dihe-in -111.39, 114.64 APE8-rot-in 323.79 APE67-dihe-in -65.1, -19.0 -57.03, -32.94 APE12-dist-in 10.066 APE11-dist-in 11.836 APE10-dist-in 6.539 APE9-dist-in 4.032 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.51 0.197 0.239 C 320 283 13 0 0 5 [[183, 456]] 1.0 6o9d TKL_IRAK4_HUMAN TKL 5.1e-84 287.9 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6O9DD Q9NWZ3 164 458 460.0 LTY:501 Type1 Inactive DFGin 6.899 14.318 BLAminus -134.66, 178.58 59.54, 82.94 -104.76, 14.4 302.36, 96.51 -59.1, -33.56 in-out in 8.73 Saltbr-out 4.078 HRD-in -68.8, -51.26 82.92, -3.16 out-in-in SNCoii in-in ActLoopNT-in 2.787 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -114.38, 156.72 APE9-dihe-na 130.79, 174.85 APE8-dihe-in -97.61, 110.6 APE8-rot-in 318.14 APE67-dihe-in -67.31, -17.64 -49.18, -44.21 APE12-dist-in 10.285 APE11-dist-in 11.769 APE10-dist-in 6.402 APE9-dist-in 4.244 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.51 0.197 0.239 D 320 284 11 0 0 3 [[183, 456]] 1.0 6o9d TKL_IRAK4_HUMAN TKL 5.1e-84 287.9 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

PDB: 6O9D — TKL IRAK4_HUMAN

Total number of chains: 4
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6O9DA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 6O9DA Q9NWZ3 162 458 460.0 LTY:501 Type1 Inactive DFGin 6.707 14.456 BLAminus -127.76, -176.84 57.79, 87.99 -106.68, 3.04 297.04, 103.76 -53.04, -31.02 in-out in 8.335 Saltbr-out 3.618 HRD-in -61.91, -55.52 80.82, -6.22 out-in-in SNCoii in-in ActLoopNT-in 2.796 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -125.17, 155.38 APE9-dihe-na 127.36, -176.8 APE8-dihe-in -102.61, 119.68 APE8-rot-in 323.19 APE67-dihe-in -59.01, -22.88 -47.44, -49.99 APE12-dist-in 9.901 APE11-dist-in 11.599 APE10-dist-in 6.247 APE9-dist-in 3.911 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.51 0.197 0.239 A 320 286 11 0 0 4 [[183, 456]] 1.0 6o9d Homo sapiens TKL_IRAK4_HUMAN TKL 5.1e-84 287.9 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6O9DB Q9NWZ3 163 458 460.0 LTY:501 Type1 Inactive DFGin 7.057 13.951 BLAminus -143.03, -179.16 58.94, 82.95 -104.14, 17.08 307.96, 103.48 -62.26, -32.09 in-out in 8.688 Saltbr-out 4.207 HRD-in -62.85, -48.11 75.04, -10.08 out-in-in SNCoii in-in ActLoopNT-in 2.931 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -116.13, 158.27 APE9-dihe-na 134.69, -173.08 APE8-dihe-in -118.39, 112.91 APE8-rot-in 312.26 APE67-dihe-in -64.54, -21.64 -47.5, -39.01 APE12-dist-in 10.134 APE11-dist-in 11.762 APE10-dist-in 6.303 APE9-dist-in 4.078 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.51 0.197 0.239 B 320 284 12 0 0 5 [[183, 456]] 1.0 6o9d Homo sapiens TKL_IRAK4_HUMAN TKL 5.1e-84 287.9 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6O9DC Q9NWZ3 163 458 460.0 LTY:501 Type1 Active DFGin 6.921 14.055 BLAminus -144.04, 172.46 65.41, 89.1 -109.46, 16.79 309.79, 96.88 -60.57, -25.46 in-in in 8.638 Saltbr-in 3.243 HRD-in -67.13, -59.39 84.36, 2.8 in-in-in SNCiii in-in ActLoopNT-in 2.917 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -122.08, 166.4 APE9-dihe-na 121.39, -170.65 APE8-dihe-in -111.39, 114.64 APE8-rot-in 323.79 APE67-dihe-in -65.1, -19.0 -57.03, -32.94 APE12-dist-in 10.066 APE11-dist-in 11.836 APE10-dist-in 6.539 APE9-dist-in 4.032 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.51 0.197 0.239 C 320 283 13 0 0 5 [[183, 456]] 1.0 6o9d Homo sapiens TKL_IRAK4_HUMAN TKL 5.1e-84 287.9 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6O9DD Q9NWZ3 164 458 460.0 LTY:501 Type1 Inactive DFGin 6.899 14.318 BLAminus -134.66, 178.58 59.54, 82.94 -104.76, 14.4 302.36, 96.51 -59.1, -33.56 in-out in 8.73 Saltbr-out 4.078 HRD-in -68.8, -51.26 82.92, -3.16 out-in-in SNCoii in-in ActLoopNT-in 2.787 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -114.38, 156.72 APE9-dihe-na 130.79, 174.85 APE8-dihe-in -97.61, 110.6 APE8-rot-in 318.14 APE67-dihe-in -67.31, -17.64 -49.18, -44.21 APE12-dist-in 10.285 APE11-dist-in 11.769 APE10-dist-in 6.402 APE9-dist-in 4.244 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.51 0.197 0.239 D 320 284 11 0 0 3 [[183, 456]] 1.0 6o9d Homo sapiens TKL_IRAK4_HUMAN TKL 5.1e-84 287.9 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

PDB: 6O9D — TKL IRAK4_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name