PDB: 6O94 — TKL IRAK4_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6O94A
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 6O94A Q9NWZ3 163 458 460.0 LRS:502 Type1 Inactive DFGin 6.98 13.957 BLAminus -123.25, 179.18 58.62, 91.23 -110.31, 12.12 305.58, 96.78 -63.69, -27.63 in-out in 9.114 Saltbr-out 5.024 HRD-in -68.39, -52.68 75.29, -1.68 out-in-in SNCoii in-in ActLoopNT-in 2.837 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -126.99, 140.47 APE9-dihe-na 148.46, -177.74 APE8-dihe-in -101.2, 107.55 APE8-rot-in 306.34 APE67-dihe-in -55.1, -20.47 -45.77, -47.94 APE12-dist-in 10.072 APE11-dist-in 12.066 APE10-dist-in 7.325 APE9-dist-in 5.218 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 1.98 0.184 0.215 A 320 292 4 0 0 4 [[183, 456]] 1.0 6o94 TKL_IRAK4_HUMAN TKL 5.1e-84 287.9 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6O94B Q9NWZ3 162 458 460.0 LRS:502 Type1 Inactive DFGin 6.899 14.028 BLAminus -122.58, 179.95 63.12, 86.64 -108.65, 9.89 303.71, 93.33 -58.6, -27.16 in-out in 8.998 Saltbr-out 4.913 HRD-in -65.66, -51.1 74.78, 1.16 out-in-in SNCoii in-in ActLoopNT-in 2.819 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -133.21, 144.66 APE9-dihe-na 140.06, 177.25 APE8-dihe-in -95.53, 110.29 APE8-rot-in 309.4 APE67-dihe-in -63.88, -19.8 -59.96, -25.96 APE12-dist-in 10.268 APE11-dist-in 12.099 APE10-dist-in 7.079 APE9-dist-in 4.846 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 1.98 0.184 0.215 B 320 293 4 0 0 4 [[183, 456]] 1.0 6o94 TKL_IRAK4_HUMAN TKL 5.1e-84 287.9 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6O94C Q9NWZ3 163 458 460.0 LRS:501 Type1 Inactive DFGin 6.59 14.128 BLAminus -121.22, 176.46 62.3, 93.01 -113.1, 16.55 308.78, 90.13 -63.81, -32.68 in-out in 8.686 Saltbr-out 4.062 HRD-in -68.33, -51.83 77.7, -5.17 out-in-in SNCoii in-in ActLoopNT-in 2.798 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -126.28, 149.13 APE9-dihe-na 136.69, -178.03 APE8-dihe-in -101.68, 113.37 APE8-rot-in 311.59 APE67-dihe-in -65.13, -21.18 -43.64, -46.59 APE12-dist-in 9.944 APE11-dist-in 12.02 APE10-dist-in 6.675 APE9-dist-in 4.349 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 1.98 0.184 0.215 C 320 286 10 0 0 4 [[183, 456]] 1.0 6o94 TKL_IRAK4_HUMAN TKL 5.1e-84 287.9 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6O94D Q9NWZ3 163 458 460.0 LRS:501 Type1 Inactive DFGin 7.003 14.021 BLAminus -126.53, 176.59 61.66, 94.12 -114.42, 13.3 307.72, 104.0 -58.57, -29.78 in-out in 8.917 Saltbr-out 4.892 HRD-in -70.14, -50.46 72.65, -1.5 out-in-in SNCoii in-in ActLoopNT-in 2.784 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -122.81, 156.44 APE9-dihe-na 122.83, -176.0 APE8-dihe-in -107.14, 110.01 APE8-rot-in 318.74 APE67-dihe-in -57.74, -23.07 -42.07, -49.71 APE12-dist-in 10.287 APE11-dist-in 12.068 APE10-dist-in 6.673 APE9-dist-in 4.369 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 1.98 0.184 0.215 D 320 285 11 0 0 5 [[183, 456]] 1.0 6o94 TKL_IRAK4_HUMAN TKL 5.1e-84 287.9 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

PDB: 6O94 — TKL IRAK4_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6O94A
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 6O94A Q9NWZ3 163 458 460.0 LRS:502 Type1 Inactive DFGin 6.98 13.957 BLAminus -123.25, 179.18 58.62, 91.23 -110.31, 12.12 305.58, 96.78 -63.69, -27.63 in-out in 9.114 Saltbr-out 5.024 HRD-in -68.39, -52.68 75.29, -1.68 out-in-in SNCoii in-in ActLoopNT-in 2.837 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -126.99, 140.47 APE9-dihe-na 148.46, -177.74 APE8-dihe-in -101.2, 107.55 APE8-rot-in 306.34 APE67-dihe-in -55.1, -20.47 -45.77, -47.94 APE12-dist-in 10.072 APE11-dist-in 12.066 APE10-dist-in 7.325 APE9-dist-in 5.218 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 1.98 0.184 0.215 A 320 292 4 0 0 4 [[183, 456]] 1.0 6o94 Homo sapiens TKL_IRAK4_HUMAN TKL 5.1e-84 287.9 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6O94B Q9NWZ3 162 458 460.0 LRS:502 Type1 Inactive DFGin 6.899 14.028 BLAminus -122.58, 179.95 63.12, 86.64 -108.65, 9.89 303.71, 93.33 -58.6, -27.16 in-out in 8.998 Saltbr-out 4.913 HRD-in -65.66, -51.1 74.78, 1.16 out-in-in SNCoii in-in ActLoopNT-in 2.819 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -133.21, 144.66 APE9-dihe-na 140.06, 177.25 APE8-dihe-in -95.53, 110.29 APE8-rot-in 309.4 APE67-dihe-in -63.88, -19.8 -59.96, -25.96 APE12-dist-in 10.268 APE11-dist-in 12.099 APE10-dist-in 7.079 APE9-dist-in 4.846 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 1.98 0.184 0.215 B 320 293 4 0 0 4 [[183, 456]] 1.0 6o94 Homo sapiens TKL_IRAK4_HUMAN TKL 5.1e-84 287.9 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6O94C Q9NWZ3 163 458 460.0 LRS:501 Type1 Inactive DFGin 6.59 14.128 BLAminus -121.22, 176.46 62.3, 93.01 -113.1, 16.55 308.78, 90.13 -63.81, -32.68 in-out in 8.686 Saltbr-out 4.062 HRD-in -68.33, -51.83 77.7, -5.17 out-in-in SNCoii in-in ActLoopNT-in 2.798 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -126.28, 149.13 APE9-dihe-na 136.69, -178.03 APE8-dihe-in -101.68, 113.37 APE8-rot-in 311.59 APE67-dihe-in -65.13, -21.18 -43.64, -46.59 APE12-dist-in 9.944 APE11-dist-in 12.02 APE10-dist-in 6.675 APE9-dist-in 4.349 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 1.98 0.184 0.215 C 320 286 10 0 0 4 [[183, 456]] 1.0 6o94 Homo sapiens TKL_IRAK4_HUMAN TKL 5.1e-84 287.9 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6O94D Q9NWZ3 163 458 460.0 LRS:501 Type1 Inactive DFGin 7.003 14.021 BLAminus -126.53, 176.59 61.66, 94.12 -114.42, 13.3 307.72, 104.0 -58.57, -29.78 in-out in 8.917 Saltbr-out 4.892 HRD-in -70.14, -50.46 72.65, -1.5 out-in-in SNCoii in-in ActLoopNT-in 2.784 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -122.81, 156.44 APE9-dihe-na 122.83, -176.0 APE8-dihe-in -107.14, 110.01 APE8-rot-in 318.74 APE67-dihe-in -57.74, -23.07 -42.07, -49.71 APE12-dist-in 10.287 APE11-dist-in 12.068 APE10-dist-in 6.673 APE9-dist-in 4.369 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 1.98 0.184 0.215 D 320 285 11 0 0 5 [[183, 456]] 1.0 6o94 Homo sapiens TKL_IRAK4_HUMAN TKL 5.1e-84 287.9 5 266 262 328 329 330 332 334 213 233 237 308 310 309 311 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

PDB: 6O94 — TKL IRAK4_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name