PDB: 6LXY — TKL IRAK4_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6LXYB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 6LXYA Q9NWZ3 163 458 460.0 EXF:501 Type1 Inactive DFGin 6.9967 14.0491 BLAminus -130.85, 177.02 62.25, 85.69 -105.57, 13.21 307.3, 97.03 -58.17, -30.36 in-out in 8.9293 Saltbr-out 5.3622 HRD-in -67.47, -54.1 77.02, 0.48 out-in-in SNCoii in-in ActLoopNT-in 2.8192 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -125.95, 147.66 APE9-dihe-na 135.07, -175.38 APE8-dihe-in -106.14, 112.07 APE8-rot-in 312.29 APE67-dihe-in -59.29, -20.88 -52.35, -43.4 APE12-dist-in 10.1915 APE11-dist-in 11.7043 APE10-dist-in 6.4389 APE9-dist-in 4.3573 None TPO345,SEP346 TPO345,SEP346 XRAY 2.19 0.202 0.231 A 305.0 294.0 2 30 28 2 [[183, 456]] 1.0 6lxy TKL_IRAK4_HUMAN TKL 4.3e-84 288.1 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6LXYB Q9NWZ3 163 459 460.0 EXF:502 Type1 None DFGin 6.9731 14.1366 BLAminus -129.45, 177.84 61.74, 86.54 -106.07, 12.43 306.08, 97.48 -57.61, -29.04 in-none in 9.0982 Saltbr-none 999.0 HRD-in -68.65, -53.21 75.68, 1.0 none-in-in SNCnii in-in ActLoopNT-in 2.8068 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -126.47, 149.33 APE9-dihe-na 135.3, -175.41 APE8-dihe-in -105.49, 112.4 APE8-rot-in 312.11 APE67-dihe-in -59.55, -21.17 -51.5, -42.55 APE12-dist-in 10.1894 APE11-dist-in 11.6864 APE10-dist-in 6.444 APE9-dist-in 4.3325 None TPO345,SEP346 TPO345,SEP346 XRAY 2.19 0.202 0.231 B 305.0 297.0 0 30 30 0 [[183, 456]] 1.0 6lxy TKL_IRAK4_HUMAN TKL 4.3e-84 288.1 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6LXYD Q9NWZ3 162 459 460.0 EXF:502 Type1 Inactive DFGin 7.0024 14.1156 BLAminus -130.62, 177.55 62.4, 85.91 -106.35, 12.8 307.19, 98.16 -58.64, -30.18 in-out in 8.9428 Saltbr-out 5.3537 HRD-in -67.38, -53.42 77.14, -1.48 out-in-in SNCoii in-in ActLoopNT-in 2.7863 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -125.01, 149.8 APE9-dihe-na 134.89, -175.28 APE8-dihe-in -104.95, 111.45 APE8-rot-in 311.34 APE67-dihe-in -58.57, -21.72 -44.58, -48.25 APE12-dist-in 10.314 APE11-dist-in 11.9545 APE10-dist-in 6.613 APE9-dist-in 4.2536 None TPO345,SEP346 TPO345,SEP346 XRAY 2.19 0.202 0.231 D 305.0 293.0 5 30 25 5 [[183, 456]] 1.0 6lxy TKL_IRAK4_HUMAN TKL 4.3e-84 288.1 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6LXYE Q9NWZ3 164 458 460.0 EXF:502 Type1 Inactive DFGin 6.9536 14.1587 BLAminus -130.3, 176.57 62.62, 85.73 -105.89, 13.23 306.79, 97.59 -58.45, -29.69 in-out in 8.9309 Saltbr-out 5.3907 HRD-in -66.96, -52.89 76.03, -0.37 out-in-in SNCoii in-in ActLoopNT-in 2.7953 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -125.25, 150.73 APE9-dihe-na 134.77, -173.9 APE8-dihe-in -105.72, 111.9 APE8-rot-in 311.85 APE67-dihe-in -56.93, -22.86 -45.56, -48.25 APE12-dist-in 10.3091 APE11-dist-in 11.9048 APE10-dist-in 6.6072 APE9-dist-in 4.2918 None TPO345,SEP346 TPO345,SEP346 XRAY 2.19 0.202 0.231 E 305.0 288.0 7 30 23 7 [[183, 456]] 1.0 6lxy TKL_IRAK4_HUMAN TKL 4.3e-84 288.1 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

PDB: 6LXY — TKL IRAK4_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 6LXYB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 6LXYA Q9NWZ3 163 458 460.0 EXF:501 Type1 Inactive DFGin 6.9967 14.0491 BLAminus -130.85, 177.02 62.25, 85.69 -105.57, 13.21 307.3, 97.03 -58.17, -30.36 in-out in 8.9293 Saltbr-out 5.3622 HRD-in -67.47, -54.1 77.02, 0.48 out-in-in SNCoii in-in ActLoopNT-in 2.8192 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -125.95, 147.66 APE9-dihe-na 135.07, -175.38 APE8-dihe-in -106.14, 112.07 APE8-rot-in 312.29 APE67-dihe-in -59.29, -20.88 -52.35, -43.4 APE12-dist-in 10.1915 APE11-dist-in 11.7043 APE10-dist-in 6.4389 APE9-dist-in 4.3573 None TPO345,SEP346 TPO345,SEP346 XRAY 2.19 0.202 0.231 A 305.0 294.0 2 30 28 2 [[183, 456]] 1.0 6lxy Homo sapiens TKL_IRAK4_HUMAN TKL 4.3e-84 288.1 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6LXYB Q9NWZ3 163 459 460.0 EXF:502 Type1 None DFGin 6.9731 14.1366 BLAminus -129.45, 177.84 61.74, 86.54 -106.07, 12.43 306.08, 97.48 -57.61, -29.04 in-none in 9.0982 Saltbr-none 999.0 HRD-in -68.65, -53.21 75.68, 1.0 none-in-in SNCnii in-in ActLoopNT-in 2.8068 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -126.47, 149.33 APE9-dihe-na 135.3, -175.41 APE8-dihe-in -105.49, 112.4 APE8-rot-in 312.11 APE67-dihe-in -59.55, -21.17 -51.5, -42.55 APE12-dist-in 10.1894 APE11-dist-in 11.6864 APE10-dist-in 6.444 APE9-dist-in 4.3325 None TPO345,SEP346 TPO345,SEP346 XRAY 2.19 0.202 0.231 B 305.0 297.0 0 30 30 0 [[183, 456]] 1.0 6lxy Homo sapiens TKL_IRAK4_HUMAN TKL 4.3e-84 288.1 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6LXYD Q9NWZ3 162 459 460.0 EXF:502 Type1 Inactive DFGin 7.0024 14.1156 BLAminus -130.62, 177.55 62.4, 85.91 -106.35, 12.8 307.19, 98.16 -58.64, -30.18 in-out in 8.9428 Saltbr-out 5.3537 HRD-in -67.38, -53.42 77.14, -1.48 out-in-in SNCoii in-in ActLoopNT-in 2.7863 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -125.01, 149.8 APE9-dihe-na 134.89, -175.28 APE8-dihe-in -104.95, 111.45 APE8-rot-in 311.34 APE67-dihe-in -58.57, -21.72 -44.58, -48.25 APE12-dist-in 10.314 APE11-dist-in 11.9545 APE10-dist-in 6.613 APE9-dist-in 4.2536 None TPO345,SEP346 TPO345,SEP346 XRAY 2.19 0.202 0.231 D 305.0 293.0 5 30 25 5 [[183, 456]] 1.0 6lxy Homo sapiens TKL_IRAK4_HUMAN TKL 4.3e-84 288.1 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6LXYE Q9NWZ3 164 458 460.0 EXF:502 Type1 Inactive DFGin 6.9536 14.1587 BLAminus -130.3, 176.57 62.62, 85.73 -105.89, 13.23 306.79, 97.59 -58.45, -29.69 in-out in 8.9309 Saltbr-out 5.3907 HRD-in -66.96, -52.89 76.03, -0.37 out-in-in SNCoii in-in ActLoopNT-in 2.7953 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -125.25, 150.73 APE9-dihe-na 134.77, -173.9 APE8-dihe-in -105.72, 111.9 APE8-rot-in 311.85 APE67-dihe-in -56.93, -22.86 -45.56, -48.25 APE12-dist-in 10.3091 APE11-dist-in 11.9048 APE10-dist-in 6.6072 APE9-dist-in 4.2918 None TPO345,SEP346 TPO345,SEP346 XRAY 2.19 0.202 0.231 E 305.0 288.0 7 30 23 7 [[183, 456]] 1.0 6lxy Homo sapiens TKL_IRAK4_HUMAN TKL 4.3e-84 288.1 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

PDB: 6LXY — TKL IRAK4_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name