PDB: 6F3I — TKL IRAK4_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 6F3IB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 6F3IA Q9NWZ3 165 458 460.0 CKN:501 Type1 Inactive DFGin 7.0541 14.3219 BLAminus -123.52, -179.8 60.09, 89.16 -112.89, 21.06 305.23, 95.52 -66.66, -30.45 in-out in 8.6589 Saltbr-out 8.1067 HRD-in -71.48, -51.41 77.44, -5.11 out-in-in SNCoii in-in ActLoopNT-in 2.7963 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -124.09, 147.59 APE9-dihe-na 131.67, -176.65 APE8-dihe-in -98.22, 114.27 APE8-rot-in 316.92 APE67-dihe-in -58.79, -21.5 -51.79, -39.53 APE12-dist-in 10.2249 APE11-dist-in 12.0072 APE10-dist-in 6.5371 APE9-dist-in 4.3271 None TPO345,SEP346 TPO345,SEP346 XRAY 2.14 0.237 0.27 A 322.0 260.0 34 30 23 7 [[183, 456]] 1.0 6f3i TKL_IRAK4_HUMAN TKL 5.2e-84 287.9 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6F3IB Q9NWZ3 164 458 460.0 CKN:502 Type1 Inactive DFGin 7.0734 14.7278 BLAminus -124.14, 177.7 62.74, 84.47 -108.24, 21.83 305.38, 94.82 -65.48, -30.96 in-out in 9.2285 Saltbr-out 6.0168 HRD-in -71.3, -51.64 77.0, -4.42 out-in-in SNCoii in-in ActLoopNT-in 2.8027 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -125.51, 147.67 APE9-dihe-na 131.82, -176.31 APE8-dihe-in -97.78, 113.9 APE8-rot-in 318.2 APE67-dihe-in -58.63, -21.1 -51.98, -39.95 APE12-dist-in 10.2485 APE11-dist-in 11.8868 APE10-dist-in 6.4604 APE9-dist-in 4.3589 None TPO345,SEP346 TPO345,SEP346 XRAY 2.14 0.237 0.27 B 322.0 281.0 14 30 23 7 [[183, 456]] 1.0 6f3i TKL_IRAK4_HUMAN TKL 5.2e-84 287.9 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

PDB: 6F3I — TKL IRAK4_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 6F3IB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 6F3IA Q9NWZ3 165 458 460.0 CKN:501 Type1 Inactive DFGin 7.0541 14.3219 BLAminus -123.52, -179.8 60.09, 89.16 -112.89, 21.06 305.23, 95.52 -66.66, -30.45 in-out in 8.6589 Saltbr-out 8.1067 HRD-in -71.48, -51.41 77.44, -5.11 out-in-in SNCoii in-in ActLoopNT-in 2.7963 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -124.09, 147.59 APE9-dihe-na 131.67, -176.65 APE8-dihe-in -98.22, 114.27 APE8-rot-in 316.92 APE67-dihe-in -58.79, -21.5 -51.79, -39.53 APE12-dist-in 10.2249 APE11-dist-in 12.0072 APE10-dist-in 6.5371 APE9-dist-in 4.3271 None TPO345,SEP346 TPO345,SEP346 XRAY 2.14 0.237 0.27 A 322.0 260.0 34 30 23 7 [[183, 456]] 1.0 6f3i Homo sapiens TKL_IRAK4_HUMAN TKL 5.2e-84 287.9 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6F3IB Q9NWZ3 164 458 460.0 CKN:502 Type1 Inactive DFGin 7.0734 14.7278 BLAminus -124.14, 177.7 62.74, 84.47 -108.24, 21.83 305.38, 94.82 -65.48, -30.96 in-out in 9.2285 Saltbr-out 6.0168 HRD-in -71.3, -51.64 77.0, -4.42 out-in-in SNCoii in-in ActLoopNT-in 2.8027 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -125.51, 147.67 APE9-dihe-na 131.82, -176.31 APE8-dihe-in -97.78, 113.9 APE8-rot-in 318.2 APE67-dihe-in -58.63, -21.1 -51.98, -39.95 APE12-dist-in 10.2485 APE11-dist-in 11.8868 APE10-dist-in 6.4604 APE9-dist-in 4.3589 None TPO345,SEP346 TPO345,SEP346 XRAY 2.14 0.237 0.27 B 322.0 281.0 14 30 23 7 [[183, 456]] 1.0 6f3i Homo sapiens TKL_IRAK4_HUMAN TKL 5.2e-84 287.9 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

PDB: 6F3I — TKL IRAK4_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name