PDB: 6F3E — TKL IRAK4_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 6F3EB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 6F3EA Q9NWZ3 164 458 460.0 CJQ:502 Type1 Inactive DFGin 6.9195 14.2196 BLAminus -136.23, 176.33 63.94, 83.09 -106.72, 21.4 311.25, 94.04 -69.13, -19.86 in-out in 8.6751 Saltbr-out 6.7089 HRD-in -63.75, -48.88 78.04, -8.73 out-none-in SNConi none-in ActLoopNT-none 999.0 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.08, 140.42 APE9-dihe-na 140.98, -176.61 APE8-dihe-in -92.66, 119.69 APE8-rot-in 314.49 APE67-dihe-in -63.0, -18.03 -56.97, -37.35 APE12-dist-in 10.5652 APE11-dist-in 11.8395 APE10-dist-in 6.6189 APE9-dist-in 4.1748 None TPO342,TPO345 TPO342,TPO345 XRAY 2.67 0.201 0.254 A 295.0 272.0 23 30 22 8 [[183, 456]] 1.0 6f3e TKL_IRAK4_HUMAN TKL 3.8e-84 288.3 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6F3EB Q9NWZ3 164 458 460.0 CJQ:501 Type1 Inactive DFGin 6.9236 14.146 BLAminus -136.52, 172.28 70.33, 84.0 -110.15, 21.49 311.14, 94.15 -69.02, -20.02 in-out in 8.6523 Saltbr-out 5.4897 HRD-in -63.87, -48.98 77.6, -8.2 out-in-in SNCoii in-in ActLoopNT-in 2.7351 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.45, 141.04 APE9-dihe-na 142.02, -175.79 APE8-dihe-in -93.38, 119.46 APE8-rot-in 315.35 APE67-dihe-in -63.37, -18.21 -57.51, -36.62 APE12-dist-in 10.4116 APE11-dist-in 11.628 APE10-dist-in 6.5015 APE9-dist-in 4.2208 None TPO342,TPO345 TPO342,TPO345 XRAY 2.67 0.201 0.254 B 295.0 284.0 11 30 25 5 [[183, 456]] 1.0 6f3e TKL_IRAK4_HUMAN TKL 3.8e-84 288.3 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

PDB: 6F3E — TKL IRAK4_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 6F3EB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 6F3EA Q9NWZ3 164 458 460.0 CJQ:502 Type1 Inactive DFGin 6.9195 14.2196 BLAminus -136.23, 176.33 63.94, 83.09 -106.72, 21.4 311.25, 94.04 -69.13, -19.86 in-out in 8.6751 Saltbr-out 6.7089 HRD-in -63.75, -48.88 78.04, -8.73 out-none-in SNConi none-in ActLoopNT-none 999.0 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.08, 140.42 APE9-dihe-na 140.98, -176.61 APE8-dihe-in -92.66, 119.69 APE8-rot-in 314.49 APE67-dihe-in -63.0, -18.03 -56.97, -37.35 APE12-dist-in 10.5652 APE11-dist-in 11.8395 APE10-dist-in 6.6189 APE9-dist-in 4.1748 None TPO342,TPO345 TPO342,TPO345 XRAY 2.67 0.201 0.254 A 295.0 272.0 23 30 22 8 [[183, 456]] 1.0 6f3e Homo sapiens TKL_IRAK4_HUMAN TKL 3.8e-84 288.3 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 6F3EB Q9NWZ3 164 458 460.0 CJQ:501 Type1 Inactive DFGin 6.9236 14.146 BLAminus -136.52, 172.28 70.33, 84.0 -110.15, 21.49 311.14, 94.15 -69.02, -20.02 in-out in 8.6523 Saltbr-out 5.4897 HRD-in -63.87, -48.98 77.6, -8.2 out-in-in SNCoii in-in ActLoopNT-in 2.7351 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.45, 141.04 APE9-dihe-na 142.02, -175.79 APE8-dihe-in -93.38, 119.46 APE8-rot-in 315.35 APE67-dihe-in -63.37, -18.21 -57.51, -36.62 APE12-dist-in 10.4116 APE11-dist-in 11.628 APE10-dist-in 6.5015 APE9-dist-in 4.2208 None TPO342,TPO345 TPO342,TPO345 XRAY 2.67 0.201 0.254 B 295.0 284.0 11 30 25 5 [[183, 456]] 1.0 6f3e Homo sapiens TKL_IRAK4_HUMAN TKL 3.8e-84 288.3 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

PDB: 6F3E — TKL IRAK4_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name