PDB: 6DUK — TYR EGFR_HUMAN

Total number of chains: 6
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 6 100.0% 6DUKA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 6DUKA P00533 701 1006 1210.0 ANP:1102,JBJ:1103 ATPlike,Type3 Inactive DFGin 4.416 14.801 BLBplus -133.89, 165.03 66.94, 37.08 -93.36, 166.29 58.42, 86.37 91.91, 6.11 out-out out 13.918 Saltbr-out 14.179 HRD-in -76.73, -64.87 85.37, -18.97 out-out-out SNCooo out-out ActLoopNT-out 7.438 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -100.39, -10.84 APE9-dihe-in -125.5, 116.79 APE8-dihe-in -80.16, 76.04 APE8-rot-na 31.69 APE67-dihe-in -76.14, -1.34 -58.18, -44.83 APE12-dist-na 17.364 APE11-dist-na 15.202 APE10-dist-na 11.776 APE9-dist-in 7.311 T790M,V948R None None XRAY 2.2 0.191 0.223 A 331 306 0 0 0 0 [[712, 970]] 1.0 6duk TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6DUKB P00533 699 1007 1210.0 ANP:1102,JBJ:1103 ATPlike,Type3 Inactive DFGin 4.681 14.65 BLBplus -136.44, 165.42 61.83, 36.22 -89.54, 161.73 53.44, 89.67 90.48, 19.39 out-out out 13.812 Saltbr-out 14.733 HRD-in -68.48, -61.78 82.94, -15.18 out-out-none SNCoon out-none ActLoopNT-out 7.292 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 128.53 APE8-dihe-in -76.17, 63.91 APE8-rot-na 26.99 APE67-dihe-in -79.83, -2.27 -51.77, -41.31 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.922 T790M,V948R None None XRAY 2.2 0.191 0.223 B 331 296 13 0 0 13 [[712, 970]] 1.0 6duk TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6DUKC P00533 699 1007 1210.0 ANP:1102,JBJ:1103 ATPlike,Type3 Inactive DFGin 4.661 14.391 BLBplus -137.36, 170.05 61.14, 32.95 -87.42, 165.36 52.89, 84.68 86.51, 15.0 out-out out 13.749 Saltbr-out 12.387 HRD-in -66.04, -61.2 80.35, -9.27 out-out-none SNCoon out-none ActLoopNT-out 8.286 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 116.92 APE8-dihe-in -77.64, 67.39 APE8-rot-na 32.93 APE67-dihe-in -71.69, -8.16 -55.72, -42.95 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.823 T790M,V948R None None XRAY 2.2 0.191 0.223 C 331 295 14 0 0 14 [[712, 970]] 1.0 6duk TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6DUKD P00533 701 1007 1210.0 ANP:1102,JBJ:1103 ATPlike,Type3 Inactive DFGin 4.605 14.634 BLBplus -137.83, 165.45 65.63, 29.61 -82.3, 167.28 56.12, 84.13 94.16, 13.47 out-out out 14.053 Saltbr-out 14.886 HRD-in -74.03, -57.71 81.46, -18.53 out-out-out SNCooo out-out ActLoopNT-out 7.321 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -76.03, 11.31 APE9-dihe-in -134.89, 121.24 APE8-dihe-in -86.59, 77.19 APE8-rot-na 34.21 APE67-dihe-in -72.84, -7.51 -59.65, -43.13 APE12-dist-na 17.747 APE11-dist-na 15.555 APE10-dist-na 11.903 APE9-dist-in 7.539 T790M,V948R None None XRAY 2.2 0.191 0.223 D 331 307 0 0 0 0 [[712, 970]] 1.0 6duk TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6DUKE P00533 698 1007 1210.0 ANP:1102,JBJ:1103 ATPlike,Type3 Inactive DFGin 4.706 14.387 BLBplus -132.31, 167.27 63.11, 42.82 -102.17, 159.55 52.62, 85.09 88.84, 16.78 out-out out 13.768 Saltbr-out 14.361 HRD-in -70.33, -59.21 85.76, -23.74 out-out-none SNCoon out-none ActLoopNT-out 7.686 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 1.83 APE9-dihe-in -127.74, 112.92 APE8-dihe-in -68.38, 64.27 APE8-rot-na 21.48 APE67-dihe-in -73.72, -8.33 -52.7, -41.98 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 13.291 APE9-dist-in 7.941 T790M,V948R None None XRAY 2.2 0.191 0.223 E 331 298 12 0 0 12 [[712, 970]] 1.0 6duk TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6DUKF P00533 701 1009 1210.0 ANP:1102,JBJ:1103 ATPlike,Type3 Inactive DFGin 4.653 14.612 BLBplus -133.82, 164.75 63.96, 32.85 -83.32, 163.7 53.83, 93.49 88.31, 19.42 out-out out 14.108 Saltbr-out 15.144 HRD-in -67.38, -62.37 88.35, -19.9 out-out-none SNCoon out-none ActLoopNT-out 7.319 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 115.72 APE8-dihe-in -80.72, 70.63 APE8-rot-na 32.98 APE67-dihe-in -75.6, -2.87 -62.49, -36.24 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.841 T790M,V948R None None XRAY 2.2 0.191 0.223 F 331 298 11 0 0 11 [[712, 970]] 1.0 6duk TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 6DUK — TYR EGFR_HUMAN

Total number of chains: 6
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 6 100.0% 6DUKA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 6DUKA P00533 701 1006 1210.0 ANP:1102,JBJ:1103 ATPlike,Type3 Inactive DFGin 4.416 14.801 BLBplus -133.89, 165.03 66.94, 37.08 -93.36, 166.29 58.42, 86.37 91.91, 6.11 out-out out 13.918 Saltbr-out 14.179 HRD-in -76.73, -64.87 85.37, -18.97 out-out-out SNCooo out-out ActLoopNT-out 7.438 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -100.39, -10.84 APE9-dihe-in -125.5, 116.79 APE8-dihe-in -80.16, 76.04 APE8-rot-na 31.69 APE67-dihe-in -76.14, -1.34 -58.18, -44.83 APE12-dist-na 17.364 APE11-dist-na 15.202 APE10-dist-na 11.776 APE9-dist-in 7.311 T790M,V948R None None XRAY 2.2 0.191 0.223 A 331 306 0 0 0 0 [[712, 970]] 1.0 6duk Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6DUKB P00533 699 1007 1210.0 ANP:1102,JBJ:1103 ATPlike,Type3 Inactive DFGin 4.681 14.65 BLBplus -136.44, 165.42 61.83, 36.22 -89.54, 161.73 53.44, 89.67 90.48, 19.39 out-out out 13.812 Saltbr-out 14.733 HRD-in -68.48, -61.78 82.94, -15.18 out-out-none SNCoon out-none ActLoopNT-out 7.292 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 128.53 APE8-dihe-in -76.17, 63.91 APE8-rot-na 26.99 APE67-dihe-in -79.83, -2.27 -51.77, -41.31 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.922 T790M,V948R None None XRAY 2.2 0.191 0.223 B 331 296 13 0 0 13 [[712, 970]] 1.0 6duk Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6DUKC P00533 699 1007 1210.0 ANP:1102,JBJ:1103 ATPlike,Type3 Inactive DFGin 4.661 14.391 BLBplus -137.36, 170.05 61.14, 32.95 -87.42, 165.36 52.89, 84.68 86.51, 15.0 out-out out 13.749 Saltbr-out 12.387 HRD-in -66.04, -61.2 80.35, -9.27 out-out-none SNCoon out-none ActLoopNT-out 8.286 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 116.92 APE8-dihe-in -77.64, 67.39 APE8-rot-na 32.93 APE67-dihe-in -71.69, -8.16 -55.72, -42.95 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.823 T790M,V948R None None XRAY 2.2 0.191 0.223 C 331 295 14 0 0 14 [[712, 970]] 1.0 6duk Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6DUKD P00533 701 1007 1210.0 ANP:1102,JBJ:1103 ATPlike,Type3 Inactive DFGin 4.605 14.634 BLBplus -137.83, 165.45 65.63, 29.61 -82.3, 167.28 56.12, 84.13 94.16, 13.47 out-out out 14.053 Saltbr-out 14.886 HRD-in -74.03, -57.71 81.46, -18.53 out-out-out SNCooo out-out ActLoopNT-out 7.321 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -76.03, 11.31 APE9-dihe-in -134.89, 121.24 APE8-dihe-in -86.59, 77.19 APE8-rot-na 34.21 APE67-dihe-in -72.84, -7.51 -59.65, -43.13 APE12-dist-na 17.747 APE11-dist-na 15.555 APE10-dist-na 11.903 APE9-dist-in 7.539 T790M,V948R None None XRAY 2.2 0.191 0.223 D 331 307 0 0 0 0 [[712, 970]] 1.0 6duk Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6DUKE P00533 698 1007 1210.0 ANP:1102,JBJ:1103 ATPlike,Type3 Inactive DFGin 4.706 14.387 BLBplus -132.31, 167.27 63.11, 42.82 -102.17, 159.55 52.62, 85.09 88.84, 16.78 out-out out 13.768 Saltbr-out 14.361 HRD-in -70.33, -59.21 85.76, -23.74 out-out-none SNCoon out-none ActLoopNT-out 7.686 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 1.83 APE9-dihe-in -127.74, 112.92 APE8-dihe-in -68.38, 64.27 APE8-rot-na 21.48 APE67-dihe-in -73.72, -8.33 -52.7, -41.98 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 13.291 APE9-dist-in 7.941 T790M,V948R None None XRAY 2.2 0.191 0.223 E 331 298 12 0 0 12 [[712, 970]] 1.0 6duk Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6DUKF P00533 701 1009 1210.0 ANP:1102,JBJ:1103 ATPlike,Type3 Inactive DFGin 4.653 14.612 BLBplus -133.82, 164.75 63.96, 32.85 -83.32, 163.7 53.83, 93.49 88.31, 19.42 out-out out 14.108 Saltbr-out 15.144 HRD-in -67.38, -62.37 88.35, -19.9 out-out-none SNCoon out-none ActLoopNT-out 7.319 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 115.72 APE8-dihe-in -80.72, 70.63 APE8-rot-na 32.98 APE67-dihe-in -75.6, -2.87 -62.49, -36.24 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.841 T790M,V948R None None XRAY 2.2 0.191 0.223 F 331 298 11 0 0 11 [[712, 970]] 1.0 6duk Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 6DUK — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name