| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TKL | RIPK2 | RIPK2_HUMAN | 5W5OA | O43353 | 5 | 310 | 540.0 | 9XA:401 | Type1 | Inactive | DFGin | 6.1363 | 13.9064 | BLAminus | -125.19, -174.64 | 59.09, 81.1 | -106.86, 24.62 | 291.19, 85.74 | -72.37, -32.43 | in-none | in | 7.781 | Saltbr-none | 999.0 | HRD-in | -58.73, -48.93 | 54.24, 22.59 | none-in-out | SNCnio | in-out | ActLoopNT-in | 2.7789 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_nnno | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 52.01 | APE8-dihe-in | -88.74, 126.44 | APE8-rot-out | 182.28 | APE67-dihe-in | -69.67, -13.84 | -102.91, 3.97 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-out | 10.7802 | None | None | None | XRAY | 2.89 | 0.219 | 0.252 | A | 310.0 | 275.0 | 31 | 33 | 18 | 15 | [[18, 292]] | 1.0 | 5w5o | TKL_RIPK2_HUMAN | TKL | 4.4e-73 | 252.0 | 4.0 | 266.0 | 263.0 | 163 | 164 | 165 | 167 | 169 | 47 | 66 | 70 | 143 | 145 | 144 | 146.0 | 211 | 196 | 191 | 190 | 189 | 188 | 187 | 186 | 185 | 96 | Receptor-interacting serine/threonine-protein kinase 2 |
| TKL | RIPK2 | RIPK2_HUMAN | 5W5OB | O43353 | 5 | 310 | 540.0 | 9XA:401 | Type1 | Inactive | DFGin | 6.075 | 13.8552 | BLAminus | -124.69, -174.05 | 60.01, 82.18 | -107.5, 25.35 | 291.09, 85.35 | -69.3, -34.49 | in-none | in | 7.852 | Saltbr-none | 999.0 | HRD-in | -59.53, -49.22 | 54.97, 22.29 | none-in-out | SNCnio | in-out | ActLoopNT-in | 2.7955 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_nnno | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 65.07 | APE8-dihe-in | -82.18, 127.67 | APE8-rot-out | 181.47 | APE67-dihe-in | -70.21, -14.17 | -102.49, 4.63 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-out | 10.7893 | None | None | None | XRAY | 2.89 | 0.219 | 0.252 | B | 310.0 | 275.0 | 31 | 33 | 18 | 15 | [[18, 292]] | 1.0 | 5w5o | TKL_RIPK2_HUMAN | TKL | 4.4e-73 | 252.0 | 4.0 | 266.0 | 263.0 | 163 | 164 | 165 | 167 | 169 | 47 | 66 | 70 | 143 | 145 | 144 | 146.0 | 211 | 196 | 191 | 190 | 189 | 188 | 187 | 186 | 185 | 96 | Receptor-interacting serine/threonine-protein kinase 2 |
| TKL | RIPK2 | RIPK2_HUMAN | 5W5OC | O43353 | 5 | 310 | 540.0 | 9XA:401 | Type1 | Inactive | DFGin | 5.9407 | 13.8497 | BLAminus | -124.15, -173.26 | 59.49, 81.39 | -107.32, 24.78 | 291.29, 84.01 | -68.0, -35.39 | in-none | in | 7.8877 | Saltbr-none | 999.0 | HRD-in | -61.12, -47.92 | 53.98, 21.23 | none-in-out | SNCnio | in-out | ActLoopNT-in | 2.7891 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_nnno | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 58.39 | APE8-dihe-in | -87.67, 127.44 | APE8-rot-out | 182.78 | APE67-dihe-in | -69.34, -14.96 | -102.25, 3.82 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-out | 10.4354 | None | None | None | XRAY | 2.89 | 0.219 | 0.252 | C | 310.0 | 275.0 | 31 | 33 | 18 | 15 | [[18, 292]] | 1.0 | 5w5o | TKL_RIPK2_HUMAN | TKL | 4.4e-73 | 252.0 | 4.0 | 266.0 | 263.0 | 163 | 164 | 165 | 167 | 169 | 47 | 66 | 70 | 143 | 145 | 144 | 146.0 | 211 | 196 | 191 | 190 | 189 | 188 | 187 | 186 | 185 | 96 | Receptor-interacting serine/threonine-protein kinase 2 |
| TKL | RIPK2 | RIPK2_HUMAN | 5W5OD | O43353 | 5 | 310 | 540.0 | 9XA:401 | Type1 | Inactive | DFGin | 6.1004 | 13.7601 | BLAminus | -124.11, -174.9 | 59.11, 83.61 | -107.83, 24.21 | 291.26, 84.74 | -71.93, -33.31 | in-none | in | 7.7124 | Saltbr-none | 999.0 | HRD-in | -58.77, -50.37 | 55.05, 21.57 | none-in-out | SNCnio | in-out | ActLoopNT-in | 2.7974 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_nnno | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 52.34 | APE8-dihe-in | -81.49, 128.95 | APE8-rot-out | 42.92 | APE67-dihe-in | -70.09, -15.04 | -103.55, 3.55 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-out | 10.6555 | None | None | None | XRAY | 2.89 | 0.219 | 0.252 | D | 310.0 | 275.0 | 31 | 33 | 18 | 15 | [[18, 292]] | 1.0 | 5w5o | TKL_RIPK2_HUMAN | TKL | 4.4e-73 | 252.0 | 4.0 | 266.0 | 263.0 | 163 | 164 | 165 | 167 | 169 | 47 | 66 | 70 | 143 | 145 | 144 | 146.0 | 211 | 196 | 191 | 190 | 189 | 188 | 187 | 186 | 185 | 96 | Receptor-interacting serine/threonine-protein kinase 2 |
| TKL | RIPK2 | RIPK2_HUMAN | 5W5OE | O43353 | 5 | 310 | 540.0 | 9XA:401 | Type1 | Inactive | DFGin | 6.1549 | 13.9143 | BLAminus | -125.32, -175.39 | 59.04, 81.44 | -106.24, 24.21 | 291.63, 86.05 | -73.47, -30.79 | in-in | in | 7.8417 | Saltbr-in | 2.7712 | HRD-in | -59.5, -48.44 | 53.52, 22.49 | in-in-out | SNCiio | in-out | ActLoopNT-in | 2.7698 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_nnno | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 63.28 | APE8-dihe-in | -87.25, 127.57 | APE8-rot-out | 182.11 | APE67-dihe-in | -69.71, -14.84 | -102.46, 3.55 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-out | 10.9221 | None | None | None | XRAY | 2.89 | 0.219 | 0.252 | E | 310.0 | 275.0 | 31 | 33 | 18 | 15 | [[18, 292]] | 1.0 | 5w5o | TKL_RIPK2_HUMAN | TKL | 4.4e-73 | 252.0 | 4.0 | 266.0 | 263.0 | 163 | 164 | 165 | 167 | 169 | 47 | 66 | 70 | 143 | 145 | 144 | 146.0 | 211 | 196 | 191 | 190 | 189 | 188 | 187 | 186 | 185 | 96 | Receptor-interacting serine/threonine-protein kinase 2 |
| TKL | RIPK2 | RIPK2_HUMAN | 5W5OF | O43353 | 5 | 310 | 540.0 | 9XA:401 | Type1 | Inactive | DFGin | 6.1021 | 13.7845 | BLAminus | -125.28, -174.81 | 60.87, 81.57 | -107.6, 24.8 | 291.53, 85.38 | -69.89, -33.64 | in-none | in | 7.7824 | Saltbr-none | 999.0 | HRD-in | -59.66, -48.54 | 55.22, 21.96 | none-in-out | SNCnio | in-out | ActLoopNT-in | 2.7916 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_nnno | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 60.19 | APE8-dihe-in | -79.96, 131.01 | APE8-rot-out | 181.63 | APE67-dihe-in | -71.08, -14.3 | -102.18, 4.63 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-out | 10.6497 | None | None | None | XRAY | 2.89 | 0.219 | 0.252 | F | 310.0 | 275.0 | 31 | 33 | 18 | 15 | [[18, 292]] | 1.0 | 5w5o | TKL_RIPK2_HUMAN | TKL | 4.4e-73 | 252.0 | 4.0 | 266.0 | 263.0 | 163 | 164 | 165 | 167 | 169 | 47 | 66 | 70 | 143 | 145 | 144 | 146.0 | 211 | 196 | 191 | 190 | 189 | 188 | 187 | 186 | 185 | 96 | Receptor-interacting serine/threonine-protein kinase 2 |
| TKL | RIPK2 | RIPK2_HUMAN | 5W5OG | O43353 | 5 | 310 | 540.0 | 9XA:401 | Type1 | Inactive | DFGin | 6.0863 | 13.8448 | BLAminus | -124.86, -174.91 | 60.12, 81.59 | -107.81, 23.84 | 291.29, 84.93 | -68.89, -36.67 | in-none | in | 7.7335 | Saltbr-none | 999.0 | HRD-in | -64.82, -49.86 | 54.77, 20.73 | none-in-out | SNCnio | in-out | ActLoopNT-in | 2.7872 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_nnno | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 60.09 | APE8-dihe-in | -78.03, 125.79 | APE8-rot-out | 184.52 | APE67-dihe-in | -69.81, -14.62 | -102.95, 4.75 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-out | 10.7849 | None | None | None | XRAY | 2.89 | 0.219 | 0.252 | G | 310.0 | 275.0 | 31 | 33 | 18 | 15 | [[18, 292]] | 1.0 | 5w5o | TKL_RIPK2_HUMAN | TKL | 4.4e-73 | 252.0 | 4.0 | 266.0 | 263.0 | 163 | 164 | 165 | 167 | 169 | 47 | 66 | 70 | 143 | 145 | 144 | 146.0 | 211 | 196 | 191 | 190 | 189 | 188 | 187 | 186 | 185 | 96 | Receptor-interacting serine/threonine-protein kinase 2 |
| TKL | RIPK2 | RIPK2_HUMAN | 5W5OH | O43353 | 5 | 310 | 540.0 | 9XA:401 | Type1 | Inactive | DFGin | 6.0893 | 13.938 | BLAminus | -123.39, -173.38 | 58.61, 81.33 | -105.97, 24.15 | 291.79, 83.79 | -68.5, -35.98 | in-in | in | 7.8994 | Saltbr-in | 2.7036 | HRD-in | -60.4, -48.42 | 54.87, 21.93 | in-in-out | SNCiio | in-out | ActLoopNT-in | 2.7873 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_nnno | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, -55.03 | APE8-dihe-in | -80.95, 128.93 | APE8-rot-out | 42.89 | APE67-dihe-in | -69.91, -14.59 | -102.1, 3.1 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-out | 10.4271 | None | None | None | XRAY | 2.89 | 0.219 | 0.252 | H | 310.0 | 275.0 | 31 | 33 | 18 | 15 | [[18, 292]] | 1.0 | 5w5o | TKL_RIPK2_HUMAN | TKL | 4.4e-73 | 252.0 | 4.0 | 266.0 | 263.0 | 163 | 164 | 165 | 167 | 169 | 47 | 66 | 70 | 143 | 145 | 144 | 146.0 | 211 | 196 | 191 | 190 | 189 | 188 | 187 | 186 | 185 | 96 | Receptor-interacting serine/threonine-protein kinase 2 |
| TKL | RIPK2 | RIPK2_HUMAN | 5W5OI | O43353 | 5 | 310 | 540.0 | 9XA:401 | Type1 | Inactive | DFGin | 5.9459 | 13.8868 | BLAminus | -123.53, -172.96 | 57.44, 81.36 | -106.55, 24.49 | 290.99, 84.39 | -68.01, -35.42 | in-none | in | 7.8441 | Saltbr-none | 999.0 | HRD-in | -60.65, -52.84 | 62.49, 6.67 | none-in-out | SNCnio | in-out | ActLoopNT-in | 2.7926 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_nnno | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, -155.66 | APE8-dihe-in | -115.79, 147.83 | APE8-rot-out | 226.21 | APE67-dihe-in | -65.02, -15.65 | -101.34, 1.94 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-out | 9.4171 | None | None | None | XRAY | 2.89 | 0.219 | 0.252 | I | 310.0 | 275.0 | 31 | 33 | 18 | 15 | [[18, 292]] | 1.0 | 5w5o | TKL_RIPK2_HUMAN | TKL | 4.4e-73 | 252.0 | 4.0 | 266.0 | 263.0 | 163 | 164 | 165 | 167 | 169 | 47 | 66 | 70 | 143 | 145 | 144 | 146.0 | 211 | 196 | 191 | 190 | 189 | 188 | 187 | 186 | 185 | 96 | Receptor-interacting serine/threonine-protein kinase 2 |
| TKL | RIPK2 | RIPK2_HUMAN | 5W5OJ | O43353 | 5 | 310 | 540.0 | 9XA:401 | Type1 | Inactive | DFGin | 6.1261 | 13.8532 | BLAminus | -125.49, -173.66 | 60.26, 80.69 | -107.0, 24.2 | 291.57, 84.27 | -70.16, -35.59 | in-in | in | 7.7874 | Saltbr-in | 2.7609 | HRD-in | -59.56, -49.0 | 54.34, 21.8 | in-in-out | SNCiio | in-out | ActLoopNT-in | 2.8093 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_nnno | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 62.31 | APE8-dihe-in | -78.64, 127.4 | APE8-rot-out | 183.39 | APE67-dihe-in | -70.3, -14.88 | -101.54, 2.76 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-out | 10.595 | None | None | None | XRAY | 2.89 | 0.219 | 0.252 | J | 310.0 | 275.0 | 31 | 33 | 18 | 15 | [[18, 292]] | 1.0 | 5w5o | TKL_RIPK2_HUMAN | TKL | 4.4e-73 | 252.0 | 4.0 | 266.0 | 263.0 | 163 | 164 | 165 | 167 | 169 | 47 | 66 | 70 | 143 | 145 | 144 | 146.0 | 211 | 196 | 191 | 190 | 189 | 188 | 187 | 186 | 185 | 96 | Receptor-interacting serine/threonine-protein kinase 2 |
| TKL | RIPK2 | RIPK2_HUMAN | 5W5OK | O43353 | 5 | 310 | 540.0 | 9XA:401 | Type1 | Inactive | DFGin | 6.1293 | 13.8059 | BLAminus | -123.47, -174.04 | 59.2, 82.79 | -107.55, 23.57 | 291.68, 84.11 | -72.29, -31.81 | in-in | in | 7.7765 | Saltbr-in | 2.8227 | HRD-in | -59.03, -50.17 | 55.62, 20.99 | in-in-out | SNCiio | in-out | ActLoopNT-in | 2.7932 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_nnno | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 54.61 | APE8-dihe-in | -86.36, 126.77 | APE8-rot-out | 185.25 | APE67-dihe-in | -70.21, -14.67 | -104.03, 4.86 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-out | 10.9333 | None | None | None | XRAY | 2.89 | 0.219 | 0.252 | K | 310.0 | 275.0 | 31 | 33 | 18 | 15 | [[18, 292]] | 1.0 | 5w5o | TKL_RIPK2_HUMAN | TKL | 4.4e-73 | 252.0 | 4.0 | 266.0 | 263.0 | 163 | 164 | 165 | 167 | 169 | 47 | 66 | 70 | 143 | 145 | 144 | 146.0 | 211 | 196 | 191 | 190 | 189 | 188 | 187 | 186 | 185 | 96 | Receptor-interacting serine/threonine-protein kinase 2 |
| TKL | RIPK2 | RIPK2_HUMAN | 5W5OL | O43353 | 5 | 310 | 540.0 | 9XA:401 | Type1 | Inactive | DFGin | 5.9768 | 13.8724 | BLAminus | -123.97, -173.69 | 59.22, 81.96 | -107.43, 24.71 | 291.89, 82.85 | -67.15, -36.07 | in-in | in | 7.9099 | Saltbr-in | 2.7447 | HRD-in | -60.31, -48.17 | 54.61, 21.38 | in-in-out | SNCiio | in-out | ActLoopNT-in | 2.7921 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_nnno | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 61.72 | APE8-dihe-in | -85.16, 131.31 | APE8-rot-out | 40.96 | APE67-dihe-in | -60.1, -15.62 | -98.81, -9.03 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-out | 10.3911 | None | None | None | XRAY | 2.89 | 0.219 | 0.252 | L | 310.0 | 275.0 | 31 | 33 | 18 | 15 | [[18, 292]] | 1.0 | 5w5o | TKL_RIPK2_HUMAN | TKL | 4.4e-73 | 252.0 | 4.0 | 266.0 | 263.0 | 163 | 164 | 165 | 167 | 169 | 47 | 66 | 70 | 143 | 145 | 144 | 146.0 | 211 | 196 | 191 | 190 | 189 | 188 | 187 | 186 | 185 | 96 | Receptor-interacting serine/threonine-protein kinase 2 |
| TKL | RIPK2 | RIPK2_HUMAN | 5W5OM | O43353 | 5 | 310 | 540.0 | 9XA:401 | Type1 | Inactive | DFGin | 6.1064 | 13.8754 | BLAminus | -124.12, -175.41 | 59.62, 81.55 | -107.4, 24.65 | 291.81, 83.79 | -71.72, -32.48 | in-none | in | 7.7974 | Saltbr-none | 999.0 | HRD-in | -58.16, -49.42 | 54.05, 21.71 | none-in-out | SNCnio | in-out | ActLoopNT-in | 2.7926 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_nnno | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 41.26 | APE8-dihe-in | -78.53, 134.02 | APE8-rot-out | 36.01 | APE67-dihe-in | -69.76, -14.56 | -101.27, 4.16 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-out | 10.0598 | None | None | None | XRAY | 2.89 | 0.219 | 0.252 | M | 310.0 | 276.0 | 30 | 33 | 18 | 15 | [[18, 292]] | 1.0 | 5w5o | TKL_RIPK2_HUMAN | TKL | 4.4e-73 | 252.0 | 4.0 | 266.0 | 263.0 | 163 | 164 | 165 | 167 | 169 | 47 | 66 | 70 | 143 | 145 | 144 | 146.0 | 211 | 196 | 191 | 190 | 189 | 188 | 187 | 186 | 185 | 96 | Receptor-interacting serine/threonine-protein kinase 2 |
| TKL | RIPK2 | RIPK2_HUMAN | 5W5ON | O43353 | 5 | 310 | 540.0 | 9XA:401 | Type1 | Inactive | DFGin | 6.0791 | 13.9277 | BLAminus | -124.88, -172.7 | 59.14, 81.77 | -106.98, 23.8 | 291.97, 82.42 | -69.42, -34.18 | in-none | in | 7.9469 | Saltbr-none | 999.0 | HRD-in | -59.84, -48.61 | 54.69, 21.04 | none-in-out | SNCnio | in-out | ActLoopNT-in | 2.7885 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_nnno | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 57.95 | APE8-dihe-in | -84.02, 128.93 | APE8-rot-out | 182.08 | APE67-dihe-in | -69.96, -13.84 | -103.42, 3.58 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-out | 10.6515 | None | None | None | XRAY | 2.89 | 0.219 | 0.252 | N | 310.0 | 272.0 | 34 | 33 | 18 | 15 | [[18, 292]] | 1.0 | 5w5o | TKL_RIPK2_HUMAN | TKL | 4.4e-73 | 252.0 | 4.0 | 266.0 | 263.0 | 163 | 164 | 165 | 167 | 169 | 47 | 66 | 70 | 143 | 145 | 144 | 146.0 | 211 | 196 | 191 | 190 | 189 | 188 | 187 | 186 | 185 | 96 | Receptor-interacting serine/threonine-protein kinase 2 |
| TKL | RIPK2 | RIPK2_HUMAN | 5W5OO | O43353 | 5 | 310 | 540.0 | 9XA:401 | Type1 | Inactive | DFGin | 6.1838 | 13.8237 | BLAminus | -123.94, -174.15 | 58.85, 81.43 | -106.41, 23.33 | 291.99, 84.7 | -71.56, -32.06 | in-in | in | 7.7913 | Saltbr-in | 2.7914 | HRD-in | -58.13, -49.83 | 54.51, 21.43 | in-in-out | SNCiio | in-out | ActLoopNT-in | 2.7873 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_nnno | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 64.54 | APE8-dihe-in | -77.78, 132.07 | APE8-rot-out | 38.52 | APE67-dihe-in | -70.42, -14.07 | -103.31, 4.58 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-out | 10.3895 | None | None | None | XRAY | 2.89 | 0.219 | 0.252 | O | 310.0 | 276.0 | 30 | 33 | 18 | 15 | [[18, 292]] | 1.0 | 5w5o | TKL_RIPK2_HUMAN | TKL | 4.4e-73 | 252.0 | 4.0 | 266.0 | 263.0 | 163 | 164 | 165 | 167 | 169 | 47 | 66 | 70 | 143 | 145 | 144 | 146.0 | 211 | 196 | 191 | 190 | 189 | 188 | 187 | 186 | 185 | 96 | Receptor-interacting serine/threonine-protein kinase 2 |
| TKL | RIPK2 | RIPK2_HUMAN | 5W5OP | O43353 | 5 | 310 | 540.0 | 9XA:401 | Type1 | Inactive | DFGin | 6.0245 | 13.8318 | BLAminus | -124.74, -174.78 | 59.93, 81.7 | -106.98, 23.2 | 291.86, 82.87 | -68.58, -34.35 | in-none | in | 7.9853 | Saltbr-none | 999.0 | HRD-in | -60.06, -48.48 | 54.27, 16.98 | none-in-out | SNCnio | in-out | ActLoopNT-in | 2.7918 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_nnno | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 52.76 | APE8-dihe-in | -83.36, 127.8 | APE8-rot-out | 182.51 | APE67-dihe-in | -70.3, -14.79 | -101.64, 2.54 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-out | 10.7436 | None | None | None | XRAY | 2.89 | 0.219 | 0.252 | P | 310.0 | 275.0 | 31 | 33 | 18 | 15 | [[18, 292]] | 1.0 | 5w5o | TKL_RIPK2_HUMAN | TKL | 4.4e-73 | 252.0 | 4.0 | 266.0 | 263.0 | 163 | 164 | 165 | 167 | 169 | 47 | 66 | 70 | 143 | 145 | 144 | 146.0 | 211 | 196 | 191 | 190 | 189 | 188 | 187 | 186 | 185 | 96 | Receptor-interacting serine/threonine-protein kinase 2 |
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TKL | RIPK2 | RIPK2_HUMAN | 5W5OA | O43353 | 5 | 310 | 540.0 | 9XA:401 | Type1 | Inactive | DFGin | 6.1363 | 13.9064 | BLAminus | -125.19, -174.64 | 59.09, 81.1 | -106.86, 24.62 | 291.19, 85.74 | -72.37, -32.43 | in-none | in | 7.781 | Saltbr-none | 999.0 | HRD-in | -58.73, -48.93 | 54.24, 22.59 | none-in-out | SNCnio | in-out | ActLoopNT-in | 2.7789 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_nnno | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 52.01 | APE8-dihe-in | -88.74, 126.44 | APE8-rot-out | 182.28 | APE67-dihe-in | -69.67, -13.84 | -102.91, 3.97 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-out | 10.7802 | None | None | None | XRAY | 2.89 | 0.219 | 0.252 | A | 310.0 | 275.0 | 31 | 33 | 18 | 15 | [[18, 292]] | 1.0 | 5w5o | Homo sapiens | TKL_RIPK2_HUMAN | TKL | 4.4e-73 | 252.0 | 4.0 | 266.0 | 263.0 | 163 | 164 | 165 | 167 | 169 | 47 | 66 | 70 | 143 | 145 | 144 | 146.0 | 211 | 196 | 191 | 190 | 189 | 188 | 187 | 186 | 185 | 96 | Receptor-interacting serine/threonine-protein kinase 2 |
| TKL | RIPK2 | RIPK2_HUMAN | 5W5OB | O43353 | 5 | 310 | 540.0 | 9XA:401 | Type1 | Inactive | DFGin | 6.075 | 13.8552 | BLAminus | -124.69, -174.05 | 60.01, 82.18 | -107.5, 25.35 | 291.09, 85.35 | -69.3, -34.49 | in-none | in | 7.852 | Saltbr-none | 999.0 | HRD-in | -59.53, -49.22 | 54.97, 22.29 | none-in-out | SNCnio | in-out | ActLoopNT-in | 2.7955 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_nnno | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 65.07 | APE8-dihe-in | -82.18, 127.67 | APE8-rot-out | 181.47 | APE67-dihe-in | -70.21, -14.17 | -102.49, 4.63 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-out | 10.7893 | None | None | None | XRAY | 2.89 | 0.219 | 0.252 | B | 310.0 | 275.0 | 31 | 33 | 18 | 15 | [[18, 292]] | 1.0 | 5w5o | Homo sapiens | TKL_RIPK2_HUMAN | TKL | 4.4e-73 | 252.0 | 4.0 | 266.0 | 263.0 | 163 | 164 | 165 | 167 | 169 | 47 | 66 | 70 | 143 | 145 | 144 | 146.0 | 211 | 196 | 191 | 190 | 189 | 188 | 187 | 186 | 185 | 96 | Receptor-interacting serine/threonine-protein kinase 2 |
| TKL | RIPK2 | RIPK2_HUMAN | 5W5OC | O43353 | 5 | 310 | 540.0 | 9XA:401 | Type1 | Inactive | DFGin | 5.9407 | 13.8497 | BLAminus | -124.15, -173.26 | 59.49, 81.39 | -107.32, 24.78 | 291.29, 84.01 | -68.0, -35.39 | in-none | in | 7.8877 | Saltbr-none | 999.0 | HRD-in | -61.12, -47.92 | 53.98, 21.23 | none-in-out | SNCnio | in-out | ActLoopNT-in | 2.7891 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_nnno | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 58.39 | APE8-dihe-in | -87.67, 127.44 | APE8-rot-out | 182.78 | APE67-dihe-in | -69.34, -14.96 | -102.25, 3.82 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-out | 10.4354 | None | None | None | XRAY | 2.89 | 0.219 | 0.252 | C | 310.0 | 275.0 | 31 | 33 | 18 | 15 | [[18, 292]] | 1.0 | 5w5o | Homo sapiens | TKL_RIPK2_HUMAN | TKL | 4.4e-73 | 252.0 | 4.0 | 266.0 | 263.0 | 163 | 164 | 165 | 167 | 169 | 47 | 66 | 70 | 143 | 145 | 144 | 146.0 | 211 | 196 | 191 | 190 | 189 | 188 | 187 | 186 | 185 | 96 | Receptor-interacting serine/threonine-protein kinase 2 |
| TKL | RIPK2 | RIPK2_HUMAN | 5W5OD | O43353 | 5 | 310 | 540.0 | 9XA:401 | Type1 | Inactive | DFGin | 6.1004 | 13.7601 | BLAminus | -124.11, -174.9 | 59.11, 83.61 | -107.83, 24.21 | 291.26, 84.74 | -71.93, -33.31 | in-none | in | 7.7124 | Saltbr-none | 999.0 | HRD-in | -58.77, -50.37 | 55.05, 21.57 | none-in-out | SNCnio | in-out | ActLoopNT-in | 2.7974 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_nnno | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 52.34 | APE8-dihe-in | -81.49, 128.95 | APE8-rot-out | 42.92 | APE67-dihe-in | -70.09, -15.04 | -103.55, 3.55 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-out | 10.6555 | None | None | None | XRAY | 2.89 | 0.219 | 0.252 | D | 310.0 | 275.0 | 31 | 33 | 18 | 15 | [[18, 292]] | 1.0 | 5w5o | Homo sapiens | TKL_RIPK2_HUMAN | TKL | 4.4e-73 | 252.0 | 4.0 | 266.0 | 263.0 | 163 | 164 | 165 | 167 | 169 | 47 | 66 | 70 | 143 | 145 | 144 | 146.0 | 211 | 196 | 191 | 190 | 189 | 188 | 187 | 186 | 185 | 96 | Receptor-interacting serine/threonine-protein kinase 2 |
| TKL | RIPK2 | RIPK2_HUMAN | 5W5OE | O43353 | 5 | 310 | 540.0 | 9XA:401 | Type1 | Inactive | DFGin | 6.1549 | 13.9143 | BLAminus | -125.32, -175.39 | 59.04, 81.44 | -106.24, 24.21 | 291.63, 86.05 | -73.47, -30.79 | in-in | in | 7.8417 | Saltbr-in | 2.7712 | HRD-in | -59.5, -48.44 | 53.52, 22.49 | in-in-out | SNCiio | in-out | ActLoopNT-in | 2.7698 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_nnno | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 63.28 | APE8-dihe-in | -87.25, 127.57 | APE8-rot-out | 182.11 | APE67-dihe-in | -69.71, -14.84 | -102.46, 3.55 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-out | 10.9221 | None | None | None | XRAY | 2.89 | 0.219 | 0.252 | E | 310.0 | 275.0 | 31 | 33 | 18 | 15 | [[18, 292]] | 1.0 | 5w5o | Homo sapiens | TKL_RIPK2_HUMAN | TKL | 4.4e-73 | 252.0 | 4.0 | 266.0 | 263.0 | 163 | 164 | 165 | 167 | 169 | 47 | 66 | 70 | 143 | 145 | 144 | 146.0 | 211 | 196 | 191 | 190 | 189 | 188 | 187 | 186 | 185 | 96 | Receptor-interacting serine/threonine-protein kinase 2 |
| TKL | RIPK2 | RIPK2_HUMAN | 5W5OF | O43353 | 5 | 310 | 540.0 | 9XA:401 | Type1 | Inactive | DFGin | 6.1021 | 13.7845 | BLAminus | -125.28, -174.81 | 60.87, 81.57 | -107.6, 24.8 | 291.53, 85.38 | -69.89, -33.64 | in-none | in | 7.7824 | Saltbr-none | 999.0 | HRD-in | -59.66, -48.54 | 55.22, 21.96 | none-in-out | SNCnio | in-out | ActLoopNT-in | 2.7916 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_nnno | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 60.19 | APE8-dihe-in | -79.96, 131.01 | APE8-rot-out | 181.63 | APE67-dihe-in | -71.08, -14.3 | -102.18, 4.63 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-out | 10.6497 | None | None | None | XRAY | 2.89 | 0.219 | 0.252 | F | 310.0 | 275.0 | 31 | 33 | 18 | 15 | [[18, 292]] | 1.0 | 5w5o | Homo sapiens | TKL_RIPK2_HUMAN | TKL | 4.4e-73 | 252.0 | 4.0 | 266.0 | 263.0 | 163 | 164 | 165 | 167 | 169 | 47 | 66 | 70 | 143 | 145 | 144 | 146.0 | 211 | 196 | 191 | 190 | 189 | 188 | 187 | 186 | 185 | 96 | Receptor-interacting serine/threonine-protein kinase 2 |
| TKL | RIPK2 | RIPK2_HUMAN | 5W5OG | O43353 | 5 | 310 | 540.0 | 9XA:401 | Type1 | Inactive | DFGin | 6.0863 | 13.8448 | BLAminus | -124.86, -174.91 | 60.12, 81.59 | -107.81, 23.84 | 291.29, 84.93 | -68.89, -36.67 | in-none | in | 7.7335 | Saltbr-none | 999.0 | HRD-in | -64.82, -49.86 | 54.77, 20.73 | none-in-out | SNCnio | in-out | ActLoopNT-in | 2.7872 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_nnno | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 60.09 | APE8-dihe-in | -78.03, 125.79 | APE8-rot-out | 184.52 | APE67-dihe-in | -69.81, -14.62 | -102.95, 4.75 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-out | 10.7849 | None | None | None | XRAY | 2.89 | 0.219 | 0.252 | G | 310.0 | 275.0 | 31 | 33 | 18 | 15 | [[18, 292]] | 1.0 | 5w5o | Homo sapiens | TKL_RIPK2_HUMAN | TKL | 4.4e-73 | 252.0 | 4.0 | 266.0 | 263.0 | 163 | 164 | 165 | 167 | 169 | 47 | 66 | 70 | 143 | 145 | 144 | 146.0 | 211 | 196 | 191 | 190 | 189 | 188 | 187 | 186 | 185 | 96 | Receptor-interacting serine/threonine-protein kinase 2 |
| TKL | RIPK2 | RIPK2_HUMAN | 5W5OH | O43353 | 5 | 310 | 540.0 | 9XA:401 | Type1 | Inactive | DFGin | 6.0893 | 13.938 | BLAminus | -123.39, -173.38 | 58.61, 81.33 | -105.97, 24.15 | 291.79, 83.79 | -68.5, -35.98 | in-in | in | 7.8994 | Saltbr-in | 2.7036 | HRD-in | -60.4, -48.42 | 54.87, 21.93 | in-in-out | SNCiio | in-out | ActLoopNT-in | 2.7873 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_nnno | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, -55.03 | APE8-dihe-in | -80.95, 128.93 | APE8-rot-out | 42.89 | APE67-dihe-in | -69.91, -14.59 | -102.1, 3.1 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-out | 10.4271 | None | None | None | XRAY | 2.89 | 0.219 | 0.252 | H | 310.0 | 275.0 | 31 | 33 | 18 | 15 | [[18, 292]] | 1.0 | 5w5o | Homo sapiens | TKL_RIPK2_HUMAN | TKL | 4.4e-73 | 252.0 | 4.0 | 266.0 | 263.0 | 163 | 164 | 165 | 167 | 169 | 47 | 66 | 70 | 143 | 145 | 144 | 146.0 | 211 | 196 | 191 | 190 | 189 | 188 | 187 | 186 | 185 | 96 | Receptor-interacting serine/threonine-protein kinase 2 |
| TKL | RIPK2 | RIPK2_HUMAN | 5W5OI | O43353 | 5 | 310 | 540.0 | 9XA:401 | Type1 | Inactive | DFGin | 5.9459 | 13.8868 | BLAminus | -123.53, -172.96 | 57.44, 81.36 | -106.55, 24.49 | 290.99, 84.39 | -68.01, -35.42 | in-none | in | 7.8441 | Saltbr-none | 999.0 | HRD-in | -60.65, -52.84 | 62.49, 6.67 | none-in-out | SNCnio | in-out | ActLoopNT-in | 2.7926 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_nnno | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, -155.66 | APE8-dihe-in | -115.79, 147.83 | APE8-rot-out | 226.21 | APE67-dihe-in | -65.02, -15.65 | -101.34, 1.94 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-out | 9.4171 | None | None | None | XRAY | 2.89 | 0.219 | 0.252 | I | 310.0 | 275.0 | 31 | 33 | 18 | 15 | [[18, 292]] | 1.0 | 5w5o | Homo sapiens | TKL_RIPK2_HUMAN | TKL | 4.4e-73 | 252.0 | 4.0 | 266.0 | 263.0 | 163 | 164 | 165 | 167 | 169 | 47 | 66 | 70 | 143 | 145 | 144 | 146.0 | 211 | 196 | 191 | 190 | 189 | 188 | 187 | 186 | 185 | 96 | Receptor-interacting serine/threonine-protein kinase 2 |
| TKL | RIPK2 | RIPK2_HUMAN | 5W5OJ | O43353 | 5 | 310 | 540.0 | 9XA:401 | Type1 | Inactive | DFGin | 6.1261 | 13.8532 | BLAminus | -125.49, -173.66 | 60.26, 80.69 | -107.0, 24.2 | 291.57, 84.27 | -70.16, -35.59 | in-in | in | 7.7874 | Saltbr-in | 2.7609 | HRD-in | -59.56, -49.0 | 54.34, 21.8 | in-in-out | SNCiio | in-out | ActLoopNT-in | 2.8093 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_nnno | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 62.31 | APE8-dihe-in | -78.64, 127.4 | APE8-rot-out | 183.39 | APE67-dihe-in | -70.3, -14.88 | -101.54, 2.76 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-out | 10.595 | None | None | None | XRAY | 2.89 | 0.219 | 0.252 | J | 310.0 | 275.0 | 31 | 33 | 18 | 15 | [[18, 292]] | 1.0 | 5w5o | Homo sapiens | TKL_RIPK2_HUMAN | TKL | 4.4e-73 | 252.0 | 4.0 | 266.0 | 263.0 | 163 | 164 | 165 | 167 | 169 | 47 | 66 | 70 | 143 | 145 | 144 | 146.0 | 211 | 196 | 191 | 190 | 189 | 188 | 187 | 186 | 185 | 96 | Receptor-interacting serine/threonine-protein kinase 2 |
| TKL | RIPK2 | RIPK2_HUMAN | 5W5OK | O43353 | 5 | 310 | 540.0 | 9XA:401 | Type1 | Inactive | DFGin | 6.1293 | 13.8059 | BLAminus | -123.47, -174.04 | 59.2, 82.79 | -107.55, 23.57 | 291.68, 84.11 | -72.29, -31.81 | in-in | in | 7.7765 | Saltbr-in | 2.8227 | HRD-in | -59.03, -50.17 | 55.62, 20.99 | in-in-out | SNCiio | in-out | ActLoopNT-in | 2.7932 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_nnno | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 54.61 | APE8-dihe-in | -86.36, 126.77 | APE8-rot-out | 185.25 | APE67-dihe-in | -70.21, -14.67 | -104.03, 4.86 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-out | 10.9333 | None | None | None | XRAY | 2.89 | 0.219 | 0.252 | K | 310.0 | 275.0 | 31 | 33 | 18 | 15 | [[18, 292]] | 1.0 | 5w5o | Homo sapiens | TKL_RIPK2_HUMAN | TKL | 4.4e-73 | 252.0 | 4.0 | 266.0 | 263.0 | 163 | 164 | 165 | 167 | 169 | 47 | 66 | 70 | 143 | 145 | 144 | 146.0 | 211 | 196 | 191 | 190 | 189 | 188 | 187 | 186 | 185 | 96 | Receptor-interacting serine/threonine-protein kinase 2 |
| TKL | RIPK2 | RIPK2_HUMAN | 5W5OL | O43353 | 5 | 310 | 540.0 | 9XA:401 | Type1 | Inactive | DFGin | 5.9768 | 13.8724 | BLAminus | -123.97, -173.69 | 59.22, 81.96 | -107.43, 24.71 | 291.89, 82.85 | -67.15, -36.07 | in-in | in | 7.9099 | Saltbr-in | 2.7447 | HRD-in | -60.31, -48.17 | 54.61, 21.38 | in-in-out | SNCiio | in-out | ActLoopNT-in | 2.7921 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_nnno | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 61.72 | APE8-dihe-in | -85.16, 131.31 | APE8-rot-out | 40.96 | APE67-dihe-in | -60.1, -15.62 | -98.81, -9.03 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-out | 10.3911 | None | None | None | XRAY | 2.89 | 0.219 | 0.252 | L | 310.0 | 275.0 | 31 | 33 | 18 | 15 | [[18, 292]] | 1.0 | 5w5o | Homo sapiens | TKL_RIPK2_HUMAN | TKL | 4.4e-73 | 252.0 | 4.0 | 266.0 | 263.0 | 163 | 164 | 165 | 167 | 169 | 47 | 66 | 70 | 143 | 145 | 144 | 146.0 | 211 | 196 | 191 | 190 | 189 | 188 | 187 | 186 | 185 | 96 | Receptor-interacting serine/threonine-protein kinase 2 |
| TKL | RIPK2 | RIPK2_HUMAN | 5W5OM | O43353 | 5 | 310 | 540.0 | 9XA:401 | Type1 | Inactive | DFGin | 6.1064 | 13.8754 | BLAminus | -124.12, -175.41 | 59.62, 81.55 | -107.4, 24.65 | 291.81, 83.79 | -71.72, -32.48 | in-none | in | 7.7974 | Saltbr-none | 999.0 | HRD-in | -58.16, -49.42 | 54.05, 21.71 | none-in-out | SNCnio | in-out | ActLoopNT-in | 2.7926 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_nnno | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 41.26 | APE8-dihe-in | -78.53, 134.02 | APE8-rot-out | 36.01 | APE67-dihe-in | -69.76, -14.56 | -101.27, 4.16 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-out | 10.0598 | None | None | None | XRAY | 2.89 | 0.219 | 0.252 | M | 310.0 | 276.0 | 30 | 33 | 18 | 15 | [[18, 292]] | 1.0 | 5w5o | Homo sapiens | TKL_RIPK2_HUMAN | TKL | 4.4e-73 | 252.0 | 4.0 | 266.0 | 263.0 | 163 | 164 | 165 | 167 | 169 | 47 | 66 | 70 | 143 | 145 | 144 | 146.0 | 211 | 196 | 191 | 190 | 189 | 188 | 187 | 186 | 185 | 96 | Receptor-interacting serine/threonine-protein kinase 2 |
| TKL | RIPK2 | RIPK2_HUMAN | 5W5ON | O43353 | 5 | 310 | 540.0 | 9XA:401 | Type1 | Inactive | DFGin | 6.0791 | 13.9277 | BLAminus | -124.88, -172.7 | 59.14, 81.77 | -106.98, 23.8 | 291.97, 82.42 | -69.42, -34.18 | in-none | in | 7.9469 | Saltbr-none | 999.0 | HRD-in | -59.84, -48.61 | 54.69, 21.04 | none-in-out | SNCnio | in-out | ActLoopNT-in | 2.7885 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_nnno | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 57.95 | APE8-dihe-in | -84.02, 128.93 | APE8-rot-out | 182.08 | APE67-dihe-in | -69.96, -13.84 | -103.42, 3.58 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-out | 10.6515 | None | None | None | XRAY | 2.89 | 0.219 | 0.252 | N | 310.0 | 272.0 | 34 | 33 | 18 | 15 | [[18, 292]] | 1.0 | 5w5o | Homo sapiens | TKL_RIPK2_HUMAN | TKL | 4.4e-73 | 252.0 | 4.0 | 266.0 | 263.0 | 163 | 164 | 165 | 167 | 169 | 47 | 66 | 70 | 143 | 145 | 144 | 146.0 | 211 | 196 | 191 | 190 | 189 | 188 | 187 | 186 | 185 | 96 | Receptor-interacting serine/threonine-protein kinase 2 |
| TKL | RIPK2 | RIPK2_HUMAN | 5W5OO | O43353 | 5 | 310 | 540.0 | 9XA:401 | Type1 | Inactive | DFGin | 6.1838 | 13.8237 | BLAminus | -123.94, -174.15 | 58.85, 81.43 | -106.41, 23.33 | 291.99, 84.7 | -71.56, -32.06 | in-in | in | 7.7913 | Saltbr-in | 2.7914 | HRD-in | -58.13, -49.83 | 54.51, 21.43 | in-in-out | SNCiio | in-out | ActLoopNT-in | 2.7873 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_nnno | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 64.54 | APE8-dihe-in | -77.78, 132.07 | APE8-rot-out | 38.52 | APE67-dihe-in | -70.42, -14.07 | -103.31, 4.58 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-out | 10.3895 | None | None | None | XRAY | 2.89 | 0.219 | 0.252 | O | 310.0 | 276.0 | 30 | 33 | 18 | 15 | [[18, 292]] | 1.0 | 5w5o | Homo sapiens | TKL_RIPK2_HUMAN | TKL | 4.4e-73 | 252.0 | 4.0 | 266.0 | 263.0 | 163 | 164 | 165 | 167 | 169 | 47 | 66 | 70 | 143 | 145 | 144 | 146.0 | 211 | 196 | 191 | 190 | 189 | 188 | 187 | 186 | 185 | 96 | Receptor-interacting serine/threonine-protein kinase 2 |
| TKL | RIPK2 | RIPK2_HUMAN | 5W5OP | O43353 | 5 | 310 | 540.0 | 9XA:401 | Type1 | Inactive | DFGin | 6.0245 | 13.8318 | BLAminus | -124.74, -174.78 | 59.93, 81.7 | -106.98, 23.2 | 291.86, 82.87 | -68.58, -34.35 | in-none | in | 7.9853 | Saltbr-none | 999.0 | HRD-in | -60.06, -48.48 | 54.27, 16.98 | none-in-out | SNCnio | in-out | ActLoopNT-in | 2.7918 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_nnno | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 52.76 | APE8-dihe-in | -83.36, 127.8 | APE8-rot-out | 182.51 | APE67-dihe-in | -70.3, -14.79 | -101.64, 2.54 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-out | 10.7436 | None | None | None | XRAY | 2.89 | 0.219 | 0.252 | P | 310.0 | 275.0 | 31 | 33 | 18 | 15 | [[18, 292]] | 1.0 | 5w5o | Homo sapiens | TKL_RIPK2_HUMAN | TKL | 4.4e-73 | 252.0 | 4.0 | 266.0 | 263.0 | 163 | 164 | 165 | 167 | 169 | 47 | 66 | 70 | 143 | 145 | 144 | 146.0 | 211 | 196 | 191 | 190 | 189 | 188 | 187 | 186 | 185 | 96 | Receptor-interacting serine/threonine-protein kinase 2 |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|