PDB: 5UIU — TKL IRAK4_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5UIUA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 5UIUA Q9NWZ3 165 458 460.0 8CG:4000 Type1 Inactive DFGin 7.0714 14.1912 BLAminus -128.0, 178.75 57.4, 86.68 -103.61, 15.12 305.49, 98.8 -59.8, -27.73 in-out in 9.029 Saltbr-out 3.9038 HRD-in -69.77, -50.91 79.77, -5.91 out-in-in SNCoii in-in ActLoopNT-in 2.7343 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -125.31, 159.24 APE9-dihe-na 132.22, -173.23 APE8-dihe-in -109.61, 111.77 APE8-rot-in 308.77 APE67-dihe-in -62.44, -17.23 -49.55, -40.12 APE12-dist-in 10.0557 APE11-dist-in 11.9469 APE10-dist-in 6.4345 APE9-dist-in 3.8865 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.02 0.186 0.204 A 323.0 289.0 5 30 25 5 [[183, 456]] 1.0 5uiu TKL_IRAK4_HUMAN TKL 5.2e-84 287.9 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5UIUB Q9NWZ3 164 458 460.0 8CG:4000 Type1 Inactive DFGin 7.0024 14.0448 BLAminus -130.9, 173.2 66.57, 85.65 -106.49, 15.18 305.82, 98.74 -60.25, -27.45 in-out in 9.0772 Saltbr-out 4.1991 HRD-in -69.82, -51.52 78.72, -3.57 out-in-in SNCoii in-in ActLoopNT-in 2.7287 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -122.42, 157.5 APE9-dihe-na 132.2, -173.12 APE8-dihe-in -109.05, 111.57 APE8-rot-in 309.25 APE67-dihe-in -61.49, -18.85 -44.37, -45.98 APE12-dist-in 10.1021 APE11-dist-in 11.9995 APE10-dist-in 6.4787 APE9-dist-in 3.9707 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.02 0.186 0.204 B 323.0 290.0 5 30 25 5 [[183, 456]] 1.0 5uiu TKL_IRAK4_HUMAN TKL 5.2e-84 287.9 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

PDB: 5UIU — TKL IRAK4_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5UIUA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 5UIUA Q9NWZ3 165 458 460.0 8CG:4000 Type1 Inactive DFGin 7.0714 14.1912 BLAminus -128.0, 178.75 57.4, 86.68 -103.61, 15.12 305.49, 98.8 -59.8, -27.73 in-out in 9.029 Saltbr-out 3.9038 HRD-in -69.77, -50.91 79.77, -5.91 out-in-in SNCoii in-in ActLoopNT-in 2.7343 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -125.31, 159.24 APE9-dihe-na 132.22, -173.23 APE8-dihe-in -109.61, 111.77 APE8-rot-in 308.77 APE67-dihe-in -62.44, -17.23 -49.55, -40.12 APE12-dist-in 10.0557 APE11-dist-in 11.9469 APE10-dist-in 6.4345 APE9-dist-in 3.8865 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.02 0.186 0.204 A 323.0 289.0 5 30 25 5 [[183, 456]] 1.0 5uiu Homo sapiens TKL_IRAK4_HUMAN TKL 5.2e-84 287.9 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5UIUB Q9NWZ3 164 458 460.0 8CG:4000 Type1 Inactive DFGin 7.0024 14.0448 BLAminus -130.9, 173.2 66.57, 85.65 -106.49, 15.18 305.82, 98.74 -60.25, -27.45 in-out in 9.0772 Saltbr-out 4.1991 HRD-in -69.82, -51.52 78.72, -3.57 out-in-in SNCoii in-in ActLoopNT-in 2.7287 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -122.42, 157.5 APE9-dihe-na 132.2, -173.12 APE8-dihe-in -109.05, 111.57 APE8-rot-in 309.25 APE67-dihe-in -61.49, -18.85 -44.37, -45.98 APE12-dist-in 10.1021 APE11-dist-in 11.9995 APE10-dist-in 6.4787 APE9-dist-in 3.9707 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.02 0.186 0.204 B 323.0 290.0 5 30 25 5 [[183, 456]] 1.0 5uiu Homo sapiens TKL_IRAK4_HUMAN TKL 5.2e-84 287.9 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

PDB: 5UIU — TKL IRAK4_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name