| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | MERTK | MERTK_HUMAN | 5TD2B | Q12866 | 577 | 861 | 999.0 | No_ligand | No_ligand | Inactive | DFGin | 6.7934 | 13.1159 | None | -144.11, 174.62 | 61.92, 63.15 | -77.51, 999.0 | 303.45, 94.64 | 999.0, 999.0 | out-out | out | 13.3511 | Saltbr-out | 12.416 | HRD-in | -68.4, -50.94 | 72.94, 5.34 | out-none-none | SNConn | none-none | ActLoopNT-none | 999.0 | ActLoopCT-none | TYR | APEdihe_nnnai | APEdist_aaan | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 999.0 | APE8-dihe-none | 999.0, 75.34 | APE8-rot-na | 32.97 | APE67-dihe-in | -69.61, -9.75 | -67.34, -19.4 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-none | 999.0 | None | None | None | XRAY | 2.68 | 0.251 | 0.3 | B | 285.0 | 242.0 | 43 | 30 | 10 | 20 | [[587, 856]] | 1.0 | 5td2 | TYR_MERTK_HUMAN | TYR | 2.9e-92 | 314.6 | 2.0 | 261.0 | 260.0 | 740 | 741 | 742 | 744 | 746 | 619 | 637 | 641 | 720 | 722 | 721 | 723.0 | 782 | 770 | 765 | 764 | 763 | 762 | 761 | 760 | 759 | 672 | Tyrosine-protein kinase Mer |
| TYR | MERTK | MERTK_HUMAN | 5TD2A | Q12866 | 577 | 861 | 999.0 | 7AE:1000 | Type1 | Inactive | DFGin | 6.1343 | 13.6506 | None | -143.3, 174.43 | 65.95, 82.51 | -104.11, 999.0 | 312.2, 105.07 | 999.0, 999.0 | none-none | none | 999.0 | Saltbr-none | 999.0 | HRD-in | -68.96, -51.07 | 72.28, 6.41 | none-none-none | SNCnnn | none-none | ActLoopNT-none | 999.0 | ActLoopCT-none | TYR | APEdihe_nnnai | APEdist_aaan | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 999.0 | APE8-dihe-none | 999.0, 97.89 | APE8-rot-na | 25.82 | APE67-dihe-in | -75.54, -1.44 | -65.62, -42.27 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-none | 999.0 | None | None | None | XRAY | 2.68 | 0.251 | 0.3 | A | 285.0 | 240.0 | 45 | 30 | 10 | 20 | [[587, 856]] | 1.0 | 5td2 | TYR_MERTK_HUMAN | TYR | 2.9e-92 | 314.6 | 2.0 | 261.0 | 260.0 | 740 | 741 | 742 | 744 | 746 | 619 | 637 | 641 | 720 | 722 | 721 | 723.0 | 782 | 770 | 765 | 764 | 763 | 762 | 761 | 760 | 759 | 672 | Tyrosine-protein kinase Mer |
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | MERTK | MERTK_HUMAN | 5TD2B | Q12866 | 577 | 861 | 999.0 | No_ligand | No_ligand | Inactive | DFGin | 6.7934 | 13.1159 | None | -144.11, 174.62 | 61.92, 63.15 | -77.51, 999.0 | 303.45, 94.64 | 999.0, 999.0 | out-out | out | 13.3511 | Saltbr-out | 12.416 | HRD-in | -68.4, -50.94 | 72.94, 5.34 | out-none-none | SNConn | none-none | ActLoopNT-none | 999.0 | ActLoopCT-none | TYR | APEdihe_nnnai | APEdist_aaan | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 999.0 | APE8-dihe-none | 999.0, 75.34 | APE8-rot-na | 32.97 | APE67-dihe-in | -69.61, -9.75 | -67.34, -19.4 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-none | 999.0 | None | None | None | XRAY | 2.68 | 0.251 | 0.3 | B | 285.0 | 242.0 | 43 | 30 | 10 | 20 | [[587, 856]] | 1.0 | 5td2 | Homo sapiens | TYR_MERTK_HUMAN | TYR | 2.9e-92 | 314.6 | 2.0 | 261.0 | 260.0 | 740 | 741 | 742 | 744 | 746 | 619 | 637 | 641 | 720 | 722 | 721 | 723.0 | 782 | 770 | 765 | 764 | 763 | 762 | 761 | 760 | 759 | 672 | Tyrosine-protein kinase Mer |
| TYR | MERTK | MERTK_HUMAN | 5TD2A | Q12866 | 577 | 861 | 999.0 | 7AE:1000 | Type1 | Inactive | DFGin | 6.1343 | 13.6506 | None | -143.3, 174.43 | 65.95, 82.51 | -104.11, 999.0 | 312.2, 105.07 | 999.0, 999.0 | none-none | none | 999.0 | Saltbr-none | 999.0 | HRD-in | -68.96, -51.07 | 72.28, 6.41 | none-none-none | SNCnnn | none-none | ActLoopNT-none | 999.0 | ActLoopCT-none | TYR | APEdihe_nnnai | APEdist_aaan | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 999.0 | APE8-dihe-none | 999.0, 97.89 | APE8-rot-na | 25.82 | APE67-dihe-in | -75.54, -1.44 | -65.62, -42.27 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-none | 999.0 | None | None | None | XRAY | 2.68 | 0.251 | 0.3 | A | 285.0 | 240.0 | 45 | 30 | 10 | 20 | [[587, 856]] | 1.0 | 5td2 | Homo sapiens | TYR_MERTK_HUMAN | TYR | 2.9e-92 | 314.6 | 2.0 | 261.0 | 260.0 | 740 | 741 | 742 | 744 | 746 | 619 | 637 | 641 | 720 | 722 | 721 | 723.0 | 782 | 770 | 765 | 764 | 763 | 762 | 761 | 760 | 759 | 672 | Tyrosine-protein kinase Mer |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|