PDB: 5S7E — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S7EB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S7EB Q04771 205 499 509.0 LU8:501,XEA:505 Type1,Allosteric Inactive DFGin 7.0009 13.4563 BLAminus -126.91, 163.64 73.07, 91.25 -103.42, 21.63 301.95, 174.37 -67.85, -18.9 in-out in 8.8128 Saltbr-out 4.7223 HRD-in -77.73, -53.3 79.65, -3.06 out-in-out SNCoio in-out ActLoopNT-in 2.929 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -117.66, 166.82 APE9-dihe-na -61.55, 164.95 APE8-dihe-in -59.98, 129.55 APE8-rot-in 299.19 APE67-dihe-in -58.01, -29.13 -63.05, -41.4 APE12-dist-in 10.2582 APE11-dist-out 6.2149 APE10-dist-out 9.0083 APE9-dist-in 3.801 Q207D None None XRAY 1.32 0.168 0.189 B 301.0 293.0 2 32 32 0 [[207, 497]] 1.0 5s7e TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7EA Q04771 202 499 509.0 LU8:501,LU8:508,LU8:509 Type1,Allosteric,Allosteric Inactive DFGin 8.3788 13.303 BLAminus -121.44, 162.36 74.46, 91.44 -103.29, 27.05 299.26, 176.52 -69.12, -17.65 in-out in 9.1784 Saltbr-out 6.1061 HRD-in -79.8, -52.73 76.32, 0.43 out-in-out SNCoio in-out ActLoopNT-in 2.8856 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -122.76, 172.59 APE9-dihe-na -57.54, 160.03 APE8-dihe-in -61.32, 126.08 APE8-rot-in 304.6 APE67-dihe-in -53.51, -32.05 -63.31, -40.67 APE12-dist-none 999.0 APE11-dist-out 6.3076 APE10-dist-out 8.8411 APE9-dist-in 3.7139 Q207D None None XRAY 1.32 0.168 0.189 A 301.0 283.0 15 32 19 13 [[207, 497]] 1.0 5s7e TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S7E — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S7EB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S7EB Q04771 205 499 509.0 LU8:501,XEA:505 Type1,Allosteric Inactive DFGin 7.0009 13.4563 BLAminus -126.91, 163.64 73.07, 91.25 -103.42, 21.63 301.95, 174.37 -67.85, -18.9 in-out in 8.8128 Saltbr-out 4.7223 HRD-in -77.73, -53.3 79.65, -3.06 out-in-out SNCoio in-out ActLoopNT-in 2.929 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -117.66, 166.82 APE9-dihe-na -61.55, 164.95 APE8-dihe-in -59.98, 129.55 APE8-rot-in 299.19 APE67-dihe-in -58.01, -29.13 -63.05, -41.4 APE12-dist-in 10.2582 APE11-dist-out 6.2149 APE10-dist-out 9.0083 APE9-dist-in 3.801 Q207D None None XRAY 1.32 0.168 0.189 B 301.0 293.0 2 32 32 0 [[207, 497]] 1.0 5s7e Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7EA Q04771 202 499 509.0 LU8:501,LU8:508,LU8:509 Type1,Allosteric,Allosteric Inactive DFGin 8.3788 13.303 BLAminus -121.44, 162.36 74.46, 91.44 -103.29, 27.05 299.26, 176.52 -69.12, -17.65 in-out in 9.1784 Saltbr-out 6.1061 HRD-in -79.8, -52.73 76.32, 0.43 out-in-out SNCoio in-out ActLoopNT-in 2.8856 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -122.76, 172.59 APE9-dihe-na -57.54, 160.03 APE8-dihe-in -61.32, 126.08 APE8-rot-in 304.6 APE67-dihe-in -53.51, -32.05 -63.31, -40.67 APE12-dist-none 999.0 APE11-dist-out 6.3076 APE10-dist-out 8.8411 APE9-dist-in 3.7139 Q207D None None XRAY 1.32 0.168 0.189 A 301.0 283.0 15 32 19 13 [[207, 497]] 1.0 5s7e Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S7E — TKL ACVR1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name